Iron Overload

"Iron Overload" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)

Descriptor ID	D019190
MeSH Number(s)	C18.452.565.500
Concept/Terms	Iron Overload Iron Overload Overload, Iron

Below are MeSH descriptors whose meaning is more general than "Iron Overload".

Diseases [C]
Nutritional and Metabolic Diseases [C18]
Metabolic Diseases [C18.452]
Iron Metabolism Disorders [C18.452.565]
Iron Overload [C18.452.565.500]

Below are MeSH descriptors whose meaning is related to "Iron Overload".

Below are MeSH descriptors whose meaning is more specific than "Iron Overload".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Iron Overload" by people in this website by year, and whether "Iron Overload" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2009 and 2012 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2006	1	0	1
2008	0	1	1
2009	2	0	2
2012	1	1	2
2021	1	0	1
2022	2	0	2
2023	1	0	1

Below are the most recent publications written about "Iron Overload" by people in Profiles.

Guglielmo FF, Barr RG, Yokoo T, Ferraioli G, Lee JT, Dillman JR, Horowitz JM, Jhaveri KS, Miller FH, Modi RY, Mojtahed A, Ohliger MA, Pirasteh A, Reeder SB, Shanbhogue K, Silva AC, Smith EN, Surabhi VR, Taouli B, Welle CL, Yeh BM, Venkatesh SK. Liver Fibrosis, Fat, and Iron Evaluation with MRI and Fibrosis and Fat Evaluation with US: A Practical Guide for Radiologists. Radiographics. 2023 06; 43(6):e220181.

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Hernando D, Zhao R, Yuan Q, Aliyari Ghasabeh M, Ruschke S, Miao X, Karampinos DC, Mao L, Harris DT, Mattison RJ, Jeng MR, Pedrosa I, Kamel IR, Vasanawala S, Yokoo T, Reeder SB. Multicenter Reproducibility of Liver Iron Quantification with 1.5-T and 3.0-T MRI. Radiology. 2023 Feb; 306(2):e213256.

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Armstrong A, Mandala A, Malhotra M, Gnana-Prakasam JP. Canonical Wnt Signaling in the Pathology of Iron Overload-Induced Oxidative Stress and Age-Related Diseases. Oxid Med Cell Longev. 2022; 2022:7163326.

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Wilson SR, Sears M, Williams E, Drapekin J, Sivakumar I, Padrino S, Desai PC, Hager W, Manwani D, Clay LJ, Field JJ, Kanter J, Cohen AJ, Saif Ur Rehman S, Lanzkron S, Little JA. Gaps in the diagnosis and management of iron overload in sickle cell disease: a 'real-world' report from the GRNDaD registry. Br J Haematol. 2021 12; 195(5):e157-e160.

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Parrow NL, Gardenghi S, Ramos P, Casu C, Grady RW, Anderson ER, Shah YM, Li H, Ginzburg YZ, Fleming RE, Rivella S. Decreased hepcidin expression in murine ß-thalassemia is associated with suppression of Bmp/Smad signaling. Blood. 2012 Mar 29; 119(13):3187-9.

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Fleming RE, Ponka P. Iron overload in human disease. N Engl J Med. 2012 Jan 26; 366(4):348-59.

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Greenberg PL, Rigsby CK, Stone RM, Deeg HJ, Gore SD, Millenson MM, Nimer SD, O'Donnell MR, Shami PJ, Kumar R. NCCN Task Force: Transfusion and iron overload in patients with myelodysplastic syndromes. J Natl Compr Canc Netw. 2009 Dec 29; 7 Suppl 9:S1-16.

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Rodriguez A, Luukkaala T, Fleming RE, Britton RS, Bacon BR, Parkkila S. Global transcriptional response to Hfe deficiency and dietary iron overload in mouse liver and duodenum. PLoS One. 2009 Sep 29; 4(9):e7212.

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Greenberg PL, Attar E, Battiwalla M, Bennett JM, Bloomfield CD, DeCastro CM, Deeg HJ, Erba HP, Foran JM, Garcia-Manero G, Gore SD, Head D, Maness LJ, Millenson M, Nimer SD, O'Donnell MR, Saba HI, Shami PJ, Spiers K, Stone RM, Tallman MS, Westervelt P. Myelodysplastic syndromes. J Natl Compr Canc Netw. 2008 Oct; 6(9):902-26.

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Schilsky ML, Fink S. Inherited metabolic liver disease. Curr Opin Gastroenterol. 2006 May; 22(3):215-22.

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