Adenosine-5'-(N-ethylcarboxamide)
"Adenosine-5'-(N-ethylcarboxamide)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stable adenosine A1 and A2 receptor agonist. Experimentally, it inhibits cAMP and cGMP phosphodiesterase activity.
| Descriptor ID |
D019830
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| MeSH Number(s) |
D03.633.100.759.590.138.025 D13.570.583.138.025 D13.570.800.096.250
|
| Concept/Terms |
Adenosine-5'-(N-ethylcarboxamide)- Adenosine-5'-(N-ethylcarboxamide)
- N6-Ethyl-carboxamido Adenosine
- Adenosine, N6-Ethyl-carboxamido
- N6 Ethyl carboxamido Adenosine
- NECA
- Adenosine-5'-N-ethyluronamide
- Adenosine 5' N ethyluronamide
- 5'-N-Ethylcarboxamidoadenosine
- 5' N Ethylcarboxamidoadenosine
- N-Ethylcarboxamidoadenosine
- N Ethylcarboxamidoadenosine
|
Below are MeSH descriptors whose meaning is more general than "Adenosine-5'-(N-ethylcarboxamide)".
Below are MeSH descriptors whose meaning is more specific than "Adenosine-5'-(N-ethylcarboxamide)".
This graph shows the total number of publications written about "Adenosine-5'-(N-ethylcarboxamide)" by people in this website by year, and whether "Adenosine-5'-(N-ethylcarboxamide)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Adenosine-5'-(N-ethylcarboxamide)" by people in Profiles.
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Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, Tilley SL. Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. J Allergy Clin Immunol. 2008 Jul; 122(1):107-13, 113.e1-7.
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Hua X, Erikson CJ, Chason KD, Rosebrock CN, Deshpande DA, Penn RB, Tilley SL. Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L25-32.
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Penn RB, Pascual RM, Kim YM, Mundell SJ, Krymskaya VP, Panettieri RA, Benovic JL. Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. J Biol Chem. 2001 Aug 31; 276(35):32648-56.
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Mundell SJ, Olah ME, Panettieri RA, Benovic JL, Penn RB. Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine. Am J Respir Cell Mol Biol. 2001 Feb; 24(2):155-63.
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Mundell SJ, Matharu AL, Kelly E, Benovic JL. Arrestin isoforms dictate differential kinetics of A2B adenosine receptor trafficking. Biochemistry. 2000 Oct 24; 39(42):12828-36.
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Mundell SJ, Benovic JL, Kelly E. A dominant negative mutant of the G protein-coupled receptor kinase 2 selectively attenuates adenosine A2 receptor desensitization. Mol Pharmacol. 1997 Jun; 51(6):991-8.
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Parkinson SJ, Alekseev AE, Gomez LA, Wagner F, Terzic A, Waldman SA. Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine. J Biol Chem. 1997 Jan 10; 272(2):754-8.
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Palmer TM, Benovic JL, Stiles GL. Agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Evidence for a G-protein-coupled receptor kinase-mediated mechanism. J Biol Chem. 1995 Dec 08; 270(49):29607-13.
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D'Ancona S, Ragazzi E, Fassina G, Mazzo M, Gusella M, Berti T. Effect of dipyridamole, 5'-(N-ethyl)-carboxamidoadenosine and 1,3-dipropyl-8-(2-amino-4-chlorophenyl)-xanthine on LOVO cell growth and morphology. Anticancer Res. 1994 Jan-Feb; 14(1A):93-7.