"Diacylglycerol Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol to a phosphatidate. EC 2.7.1.107.
| Descriptor ID |
D019852
|
| MeSH Number(s) |
D08.811.913.696.620.200
|
| Concept/Terms |
Diacylglycerol Kinase- Diacylglycerol Kinase
- Kinase, Diacylglycerol
- 1,2-Diacylglycerol Kinase
- 1,2 Diacylglycerol Kinase
- Kinase, 1,2-Diacylglycerol
- DAG Kinase
- Kinase, DAG
- Diglyceride Kinase
- Kinase, Diglyceride
|
Below are MeSH descriptors whose meaning is more general than "Diacylglycerol Kinase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol Kinase".
This graph shows the total number of publications written about "Diacylglycerol Kinase" by people in this website by year, and whether "Diacylglycerol Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diacylglycerol Kinase" by people in Profiles.
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Hernandez-Lara MA, Richard J, Deshpande DA. Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma. Am J Physiol Lung Cell Mol Physiol. 2024 Jul 01; 327(1):L3-L18.
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Singh BK, Yokoyama Y, Tanaka Y, Laczk? D, Deshpande DA, Kambayashi T. Diacylglycerol kinase zeta deficiency attenuates papain-induced type 2 airway inflammation. Cell Immunol. 2023 Nov-Dec; 393-394:104780.
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Hernandez-Lara MA, Yadav SK, Conaway S, Shah SD, Penn RB, Deshpande DA. Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation. Respir Res. 2023 Jun 10; 24(1):155.
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Hernandez-Lara MA, Yadav SK, Shah SD, Okumura M, Yokoyama Y, Penn RB, Kambayashi T, Deshpande DA. Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma. Int J Mol Sci. 2022 Oct 06; 23(19).
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Sharma P, Yadav SK, Shah SD, Javed E, Lim JM, Pan S, Nayak AP, Panettieri RA, Penn RB, Kambayashi T, Deshpande DA. Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-Signaling. Am J Respir Cell Mol Biol. 2021 12; 65(6):658-671.
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Yadav SK, Sharma P, Shah SD, Panettieri RA, Kambayashi T, Penn RB, Deshpande DA. Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase. J Cell Physiol. 2022 01; 237(1):603-616.
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Kambayashi T, Deshpande DA. The role of diacylglycerol kinases in allergic airway disease. Curr Opin Pharmacol. 2020 04; 51:50-58.
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Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA, Haczku A, Kambayashi T. Diacylglycerol kinase ? promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms. Sci Signal. 2019 09 03; 12(597).
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Epand RM, Shulga YV, Timmons HC, Perri AL, Belani JD, Perinpanathan K, Johnson-McIntire LB, Bajjalieh S, Dicu AO, Elias C, Rychnovsky SD, Topham MK. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry. 2007 Dec 11; 46(49):14225-31.