"Locus Control Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate GENETIC TRANSCRIPTION by opening and remodeling CHROMATIN structure. It may also have enhancer activity.
Descriptor ID |
D019901
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MeSH Number(s) |
G02.111.570.080.689.450 G05.360.080.689.450 G05.360.340.024.380.249
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Concept/Terms |
Locus Control Region- Locus Control Region
- Control Region, Locus
- Control Regions, Locus
- Locus Control Regions
- Region, Locus Control
- Regions, Locus Control
|
Below are MeSH descriptors whose meaning is more general than "Locus Control Region".
Below are MeSH descriptors whose meaning is more specific than "Locus Control Region".
This graph shows the total number of publications written about "Locus Control Region" by people in this website by year, and whether "Locus Control Region" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Locus Control Region" by people in Profiles.
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Isoda T, Moore AJ, He Z, Chandra V, Aida M, Denholtz M, Piet van Hamburg J, Fisch KM, Chang AN, Fahl SP, Wiest DL, Murre C. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017 Sep 21; 171(1):103-119.e18.
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Rosson D, Keshgegian AA. Frequent mutations in the mitochondrial control region DNA in breast tissue. Cancer Lett. 2004 Nov 08; 215(1):89-94.