Calcium Signaling

"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.

Descriptor ID	D020013
MeSH Number(s)	G02.111.820.800.100 G03.143.500.100 G04.835.800.100
Concept/Terms	Calcium Signaling Calcium Signaling Calcium Signalings Signaling, Calcium Signalings, Calcium Calcium Waves Calcium Waves Calcium Wave Wave, Calcium Waves, Calcium Calcium Oscillations Calcium Oscillation Oscillation, Calcium Oscillations, Calcium Calcium Spikes Calcium Spikes Calcium Spike Spike, Calcium Spikes, Calcium Calcium Puffs Calcium Puffs Calcium Puff Puff, Calcium Puffs, Calcium Calcium Sparks Calcium Sparks Calcium Spark Spark, Calcium Sparks, Calcium

Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Second Messenger Systems [G02.111.820.800]
Calcium Signaling [G02.111.820.800.100]
Metabolism [G03]
Biological Transport [G03.143]
Ion Transport [G03.143.500]
Calcium Signaling [G03.143.500.100]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Second Messenger Systems [G04.835.800]
Calcium Signaling [G04.835.800.100]

Below are MeSH descriptors whose meaning is related to "Calcium Signaling".

Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".

Calcium Signaling
Excitation Contraction Coupling

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.

Bar chart showing 155 publications over 27 distinct years, with a maximum of 12 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
1999	1	0	1
2000	2	2	4
2001	3	0	3
2002	2	2	4
2003	3	4	7
2004	7	5	12
2005	4	5	9
2006	1	6	7
2007	4	3	7
2008	2	2	4
2009	2	5	7
2010	5	5	10
2011	2	4	6
2012	1	3	4
2013	2	4	6
2014	8	2	10
2015	5	3	8
2016	5	4	9
2017	4	1	5
2018	1	3	4
2019	4	3	7
2020	1	1	2
2021	3	5	8
2022	0	3	3
2023	2	1	3
2024	3	1	4

Below are the most recent publications written about "Calcium Signaling" by people in Profiles.

De Pascali F, Inoue A, Benovic JL. Diverse pathways in GPCR-mediated activation of Ca2+ mobilization in HEK293 cells. J Biol Chem. 2024 11; 300(11):107882.

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Hasan P, Berezhnaya E, Rodr?guez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, Birch E, Beyer AM, Santos JH, Seifert EL, Elrod JW, Hajn?czky G. MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart. Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35):e2402491121.

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Dogan S, Walseth TF, Guvenc Tuna B, U?ar E, Kannan MS, Deshpande DA. CD38/cADPR-mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1. IUBMB Life. 2024 12; 76(12):1223-1233.

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Seitz A, Busch M, Kroemer J, Schneider A, Simon S, Jungmann A, Katus HA, Most P, Ritterhoff J. S100A1's single cysteine is an indispensable redox switch for the protection against diastolic calcium waves in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2024 07 01; 327(1):H000.

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Yuan Y, Arige V, Saito R, Mu Q, Brailoiu GC, Pereira GJS, Bolsover SR, Keller M, Bracher F, Grimm C, Brailoiu E, Marchant JS, Yule DI, Patel S. Two-pore channel-2 and inositol trisphosphate receptors coordinate Ca2+ signals between lysosomes and the endoplasmic reticulum. Cell Rep. 2024 01 23; 43(1):113628.

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Clements RT, Terentyeva R, Hamilton S, Janssen PML, Roder K, Martin BY, Perger F, Schneider T, Nichtova Z, Das AS, Veress R, Lee BS, Kim DG, Koren G, Stratton MS, Csordas G, Accornero F, Belevych AE, Gyorke S, Terentyev D. Sexual dimorphism in bidirectional SR-mitochondria crosstalk in ventricular cardiomyocytes. Basic Res Cardiol. 2023 05 03; 118(1):15.

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Nichtov? Z, Fernandez-Sanz C, De La Fuente S, Yuan Y, Hurst S, Lanvermann S, Tsai HY, Weaver D, Baggett A, Thompson C, Bouchet-Marquis C, V?rnai P, Seifert EL, Dorn GW, Sheu SS, Csord?s G. Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac Muscle Remodeling. Circ Res. 2023 05 26; 132(11):e171-e187.

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Carlson EJ, Francis R, Liu Y, Li P, Lyon M, Santi CM, Hook DJ, Hawkinson JE, Georg GI. Discovery and Characterization of Multiple Classes of Human CatSper Blockers. ChemMedChem. 2022 08 03; 17(15):e202000499.

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Gu?guinou M, Ibrahim S, Bourgeais J, Robert A, Pathak T, Zhang X, Crott?s D, Dupuy J, Ternant D, Monbet V, Guibon R, Flores-Romero H, Lef?vre A, Lerondel S, Le Pape A, Dumas JF, Frank PG, Girault A, Chautard R, Gu?raud F, Garc?a-S?ez AJ, Ouaissi M, Emond P, Sire O, H?rault O, Fromont-Hankard G, Vandier C, Tougeron D, Trebak M, Raoul W, Lecomte T. Curcumin and NCLX inhibitors share anti-tumoral mechanisms in microsatellite-instability-driven colorectal cancer. Cell Mol Life Sci. 2022 May 08; 79(6):284.

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Singh R, Bartok A, Paillard M, Tyburski A, Elliott M, Hajn?czky G. Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients. Sci Adv. 2022 03 18; 8(11):eabj4716.

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