"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
|
| MeSH Number(s) |
G02.111.820.800.100 G03.143.500.100 G04.835.800.100
|
| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 2 | 3 |
| 2003 | 3 | 2 | 5 |
| 2004 | 6 | 5 | 11 |
| 2005 | 4 | 4 | 8 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 3 | 5 |
| 2010 | 4 | 4 | 8 |
| 2011 | 2 | 3 | 5 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 3 | 4 |
| 2016 | 0 | 2 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2021 | 0 | 3 | 3 |
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click here.
Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Cao M, Luo X, Wu K, He X. Targeting lysosomes in human disease: from basic research to clinical applications. Signal Transduct Target Ther. 2021 11 08; 6(1):379.
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Booth DM, Várnai P, Joseph SK, Hajnóczky G. Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER. Mol Cell. 2021 09 16; 81(18):3866-3876.e2.
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Kitazawa T, Matsui T, Katsuki S, Goto A, Akagi K, Hatano N, Tokumitsu H, Takeya K, Eto M. A temporal Ca2+ desensitization of myosin light chain kinase in phasic smooth muscles induced by CaMKKß/PP2A pathways. Am J Physiol Cell Physiol. 2021 09 01; 321(3):C549-C558.
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Leo LM, Familusi B, Hoang M, Smith R, Lindenau K, Sporici KT, Brailoiu E, Abood ME, Brailoiu GC. GPR55-mediated effects on brain microvascular endothelial cells and the blood-brain barrier. Neuroscience. 2019 08 21; 414:88-98.
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Brailoiu E, Chakraborty S, Brailoiu GC, Zhao P, Barr JL, Ilies MA, Unterwald EM, Abood ME, Taylor CW. Choline Is an Intracellular Messenger Linking Extracellular Stimuli to IP3-Evoked Ca2+ Signals through Sigma-1 Receptors. Cell Rep. 2019 01 08; 26(2):330-337.e4.
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Brailoiu E, Barlow CL, Ramirez SH, Abood ME, Brailoiu GC. Effects of Platelet-Activating Factor on Brain Microvascular Endothelial Cells. Neuroscience. 2018 05 01; 377:105-113.
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Ren T, Wang J, Zhang H, Yuan P, Zhu J, Wu Y, Huang Q, Guo X, Zhang J, Ji L, Li J, Zhang H, Yang H, Xing J. MCUR1-Mediated Mitochondrial Calcium Signaling Facilitates Cell Survival of Hepatocellular Carcinoma via Reactive Oxygen Species-Dependent P53 Degradation. Antioxid Redox Signal. 2018 04 20; 28(12):1120-1136.
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Eisner V, Cupo RR, Gao E, Csordás G, Slovinsky WS, Paillard M, Cheng L, Ibetti J, Chen SR, Chuprun JK, Hoek JB, Koch WJ, Hajnóczky G. Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):E859-E868.
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Gherghina FL, Tica AA, Deliu E, Abood ME, Brailoiu GC, Brailoiu E. Effects of VPAC1 activation in nucleus ambiguus neurons. Brain Res. 2017 02 15; 1657:297-303.
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Brailoiu E, Shipsky MM, Yan G, Abood ME, Brailoiu GC. Mechanisms of modulation of brain microvascular endothelial cells function by thrombin. Brain Res. 2017 02 15; 1657:167-175.