"Alu Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
| Descriptor ID |
D020087
|
| MeSH Number(s) |
G02.111.570.080.708.330.800.800.050 G05.360.080.708.330.800.800.050 G05.360.340.024.425.800.800.050
|
| Concept/Terms |
Alu Elements- Alu Elements
- Alu Element
- Element, Alu
- Elements, Alu
- Alu Family
- Alu Families
- Families, Alu
- Family, Alu
- Alu Repetitive Sequences
- Alu Repetitive Sequence
- Repetitive Sequence, Alu
- Repetitive Sequences, Alu
- Sequence, Alu Repetitive
- Sequences, Alu Repetitive
|
Below are MeSH descriptors whose meaning is more general than "Alu Elements".
Below are MeSH descriptors whose meaning is more specific than "Alu Elements".
This graph shows the total number of publications written about "Alu Elements" by people in this website by year, and whether "Alu Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Alu Elements" by people in Profiles.
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Tsirigos A, Rigoutsos I. Alu and b1 repeats have been selectively retained in the upstream and intronic regions of genes of specific functional classes. PLoS Comput Biol. 2009 Dec; 5(12):e1000610.
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Zilberman DE, Safran M, Paz N, Amariglio N, Simon A, Fridman E, Kleinmann N, Ramon J, Rechavi G. Does RNA editing play a role in the development of urinary bladder cancer? Urol Oncol. 2011 Jan-Feb; 29(1):21-6.
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Has C, Wessagowit V, Pascucci M, Baer C, Didona B, Wilhelm C, Pedicelli C, Locatelli A, Kohlhase J, Ashton GH, Tadini G, Zambruno G, Bruckner-Tuderman L, McGrath JA, Castiglia D. Molecular basis of Kindler syndrome in Italy: novel and recurrent Alu/Alu recombination, splice site, nonsense, and frameshift mutations in the KIND1 gene. J Invest Dermatol. 2006 Aug; 126(8):1776-83.
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Tomatsu S, Orii KO, Islam MR, Shah GN, Grubb JH, Sukegawa K, Suzuki Y, Orii T, Kondo N, Sly WS. Methylation patterns of the human beta-glucuronidase gene locus: boundaries of methylation and general implications for frequent point mutations at CpG dinucleotides. Genomics. 2002 Mar; 79(3):363-75.