Demyelinating Autoimmune Diseases, CNS
"Demyelinating Autoimmune Diseases, CNS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.
| Descriptor ID |
D020278
|
| MeSH Number(s) |
C10.114.375 C10.228.140.695.562 C10.314.350 C20.111.258.250
|
| Concept/Terms |
Demyelinating Autoimmune Diseases, CNS- Demyelinating Autoimmune Diseases, CNS
- Demyelinating Autoimmune Disorders, CNS
- Demyelinating Disease, Autoimmune, CNS
- CNS Demyelinating Autoimmune Diseases
- Autoimmune Demyelinating Diseases, CNS
- Autoimmune Demyelinating Disorders, CNS
- CNS Autoimmune Demyelinating Disorders
- Demyelinating Autoimmune Diseases, Central Nervous System
- Autoimmune Demyelinating Diseases, Central Nervous System
|
Below are MeSH descriptors whose meaning is more general than "Demyelinating Autoimmune Diseases, CNS".
Below are MeSH descriptors whose meaning is more specific than "Demyelinating Autoimmune Diseases, CNS".
This graph shows the total number of publications written about "Demyelinating Autoimmune Diseases, CNS" by people in this website by year, and whether "Demyelinating Autoimmune Diseases, CNS" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 3 | 0 | 3 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Demyelinating Autoimmune Diseases, CNS" by people in Profiles.
-
Cristofanilli M, Rosenthal H, Cymring B, Gratch D, Pagano B, Xie B, Sadiq SA. Progressive multiple sclerosis cerebrospinal fluid induces inflammatory demyelination, axonal loss, and astrogliosis in mice. Exp Neurol. 2014 Nov; 261:620-32.
-
Khan RS, Dine K, Das Sarma J, Shindler KS. SIRT1 activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease. Acta Neuropathol Commun. 2014 Jan 02; 2:3.
-
O'Brien K, Fitzgerald DC, Naiken K, Alugupalli KR, Rostami AM, Gran B. Role of the innate immune system in autoimmune inflammatory demyelination. Curr Med Chem. 2008; 15(11):1105-15.
-
Dalakas MC. Inhibiting leukocyte recruitment to the brain by IVIg: is it relevant to the treatment of demyelinating CNS disorders? Brain. 2004 Dec; 127(Pt 12):2569-71.
-
Pirko I, Johnson A, Ciric B, Gamez J, Macura SI, Pease LR, Rodriguez M. In vivo magnetic resonance imaging of immune cells in the central nervous system with superparamagnetic antibodies. FASEB J. 2004 Jan; 18(1):179-82.
-
Zhang GX, Gran B, Yu S, Li J, Siglienti I, Chen X, Kamoun M, Rostami A. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J Immunol. 2003 Feb 15; 170(4):2153-60.
-
Gran B, Zhang GX, Yu S, Li J, Chen XH, Ventura ES, Kamoun M, Rostami A. IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J Immunol. 2002 Dec 15; 169(12):7104-10.
-
Mitsunaga Y, Ciric B, Van Keulen V, Warrington AE, Paz Soldan M, Bieber AJ, Rodriguez M, Pease LR. Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB J. 2002 Aug; 16(10):1325-7.
-
Bieber AJ, Warrington A, Asakura K, Ciric B, Kaveri SV, Pease LR, Rodriguez M. Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice. Glia. 2002 Mar 1; 37(3):241-9.