GTPase-Activating Proteins
"GTPase-Activating Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that activate the GTPase of specific GTP-BINDING PROTEINS.
| Descriptor ID |
D020690
|
| MeSH Number(s) |
D12.644.360.325.150 D12.776.476.325.150
|
| Concept/Terms |
GTPase-Activating Proteins- GTPase-Activating Proteins
- GTPase Activating Proteins
- GAP Proteins
- GAP Protein
- GTPase-Activating Protein
- GTPase Activating Protein
|
Below are MeSH descriptors whose meaning is more general than "GTPase-Activating Proteins".
Below are MeSH descriptors whose meaning is more specific than "GTPase-Activating Proteins".
This graph shows the total number of publications written about "GTPase-Activating Proteins" by people in this website by year, and whether "GTPase-Activating Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "GTPase-Activating Proteins" by people in Profiles.
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Nehlig A, Sperling M, Mathern G. An interview with Sarah Weckhuysen, 2017 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2017 07; 58(7):1119-1120.
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Vareechon C, Zmina SE, Karmakar M, Pearlman E, Rietsch A. Pseudomonas aeruginosa Effector ExoS Inhibits ROS Production in Human Neutrophils. . 2017 May 10; 21(5):611-618.e5.
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Wurtzel JG, Lee S, Singhal SS, Awasthi S, Ginsberg MH, Goldfinger LE. RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes. Biochem Biophys Res Commun. 2015 Nov 27; 467(4):785-91.
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Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, Ostrow LW, Matunis MJ, Wang J, Sattler R, Lloyd TE, Rothstein JD. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport. Nature. 2015 Sep 03; 525(7567):56-61.
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Lee S, Wurtzel JG, Goldfinger LE. The RLIP76 N-terminus binds ARNO to regulate PI 3-kinase, Arf6 and Rac signaling, cell spreading and migration. Biochem Biophys Res Commun. 2014 11 28; 454(4):560-5.
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Lee S, Goldfinger LE. RLIP76 regulates HIF-1 activity, VEGF expression and secretion in tumor cells, and secretome transactivation of endothelial cells. FASEB J. 2014 Sep; 28(9):4158-68.
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Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S. Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):E3109-18.
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Lee S, Wurtzel JG, Singhal SS, Awasthi S, Goldfinger LE. RALBP1/RLIP76 depletion in mice suppresses tumor growth by inhibiting tumor neovascularization. Cancer Res. 2012 Oct 15; 72(20):5165-73.
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Dong X, Tang W, Stopenski S, Brose MS, Korch C, Meinkoth JL. RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells. Endocr Relat Cancer. 2012 Aug; 19(4):575-88.
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Tsygankova OM, Ma C, Tang W, Korch C, Feldman MD, Lv Y, Brose MS, Meinkoth JL. Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol Cell Biol. 2010 Jul; 30(13):3262-74.