GTPase-Activating Proteins
"GTPase-Activating Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that activate the GTPase of specific GTP-BINDING PROTEINS.
| Descriptor ID |
D020690
|
| MeSH Number(s) |
D12.644.360.325.150 D12.776.476.325.150
|
| Concept/Terms |
GTPase-Activating Proteins- GTPase-Activating Proteins
- GTPase Activating Proteins
- GAP Proteins
- GAP Protein
- GTPase-Activating Protein
- GTPase Activating Protein
|
Below are MeSH descriptors whose meaning is more general than "GTPase-Activating Proteins".
Below are MeSH descriptors whose meaning is more specific than "GTPase-Activating Proteins".
This graph shows the total number of publications written about "GTPase-Activating Proteins" by people in this website by year, and whether "GTPase-Activating Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTPase-Activating Proteins" by people in Profiles.
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Haber AO, Jain A, Mani C, Nevler A, Agostini LC, Golan T, Palle K, Yeo CJ, Gmeiner WH, Brody JR. AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition. Mol Cancer Res. 2021 04; 19(4):565-572.
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Agostini LC, Jain A, Shupp A, Nevler A, McCarthy G, Bussard KM, Yeo CJ, Brody JR. Combined Targeting of PARG and Wee1 Causes Decreased Cell Survival and DNA Damage in an S-Phase-Dependent Manner. Mol Cancer Res. 2021 02; 19(2):207-214.
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Nehlig A, Sperling M, Mathern G. An interview with Sarah Weckhuysen, 2017 Epilepsia Prize Winner for Clinical Research. Epilepsia. 2017 07; 58(7):1119-1120.
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Dong X, Tang W, Stopenski S, Brose MS, Korch C, Meinkoth JL. RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells. Endocr Relat Cancer. 2012 Aug; 19(4):575-88.
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Tsygankova OM, Ma C, Tang W, Korch C, Feldman MD, Lv Y, Brose MS, Meinkoth JL. Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol Cell Biol. 2010 Jul; 30(13):3262-74.
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Chahdi A, Sorokin A. The role of beta(1)Pix/caveolin-1 interaction in endothelin signaling through Galpha subunits. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1330-5.
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Nellore A, Paziana K, Ma C, Tsygankova OM, Wang Y, Puttaswamy K, Iqbal AU, Franks SR, Lv Y, Troxel AB, Feldman MD, Meinkoth JL, Brose MS. Loss of Rap1GAP in papillary thyroid cancer. J Clin Endocrinol Metab. 2009 Mar; 94(3):1026-32.
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Tsygankova OM, Prendergast GV, Puttaswamy K, Wang Y, Feldman MD, Wang H, Brose MS, Meinkoth JL. Downregulation of Rap1GAP contributes to Ras transformation. Mol Cell Biol. 2007 Oct; 27(19):6647-58.
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Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G. Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell. 2006 Apr; 9(4):261-72.
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Hosey MM, Pals-Rylaarsdam R, Lee KB, Roseberry AG, Benovic JL, Gurevich VV, B?nemann M. Molecular events associated with the regulation of signaling by M2 muscarinic receptors. Life Sci. 1999; 64(6-7):363-8.