Leptin

"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.

Descriptor ID	D020738
MeSH Number(s)	D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
Concept/Terms	Leptin Leptin Obese Protein Obese Gene Product Gene Product, Obese Ob Gene Product Gene Product, Ob Ob Protein

Below are MeSH descriptors whose meaning is more general than "Leptin".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Adipokines [D06.472.699.042]
Leptin [D06.472.699.042.500]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Adipokines [D12.644.276.024]
Leptin [D12.644.276.024.500]
Peptide Hormones [D12.644.548]
Adipokines [D12.644.548.011]
Leptin [D12.644.548.011.500]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Adipokines [D12.776.467.024]
Leptin [D12.776.467.024.500]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Adipokines [D23.529.024]
Leptin [D23.529.024.500]

Below are MeSH descriptors whose meaning is related to "Leptin".

Below are MeSH descriptors whose meaning is more specific than "Leptin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.

Bar chart showing 29 publications over 17 distinct years, with a maximum of 4 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
2000	0	1	1
2001	3	0	3
2002	3	1	4
2003	1	0	1
2005	0	1	1
2006	2	0	2
2008	1	1	2
2009	1	0	1
2010	1	0	1
2011	2	1	3
2013	0	2	2
2016	1	1	2
2017	1	0	1
2018	0	1	1
2021	0	2	2

Below are the most recent publications written about "Leptin" by people in Profiles.

Fitzpatrick AM, Mutic AD, Mohammad AF, Stephenson ST, Grunwell JR. Obesity Is Associated with Sustained Symptomatology and Unique Inflammatory Features in Children with Asthma. J Allergy Clin Immunol Pract. 2022 03; 10(3):815-826.e2.

View in: PubMed
Conte M, Santoro A, Collura S, Martucci M, Battista G, Bazzocchi A, Morsiani C, Sevini F, Capri M, Monti D, Franceschi C, Salvioli S. Circulating perilipin 2 levels are associated with fat mass, inflammatory and metabolic markers and are higher in women than men. Aging (Albany NY). 2021 03 17; 13(6):7931-7942.

View in: PubMed
Hossain MJ, Levinson A, George D, Canas J, Kumar S, Balagopal PB. Vitamin D Status and Cardiovascular Risk in Obesity: Effect of Physical Activity in Nonvitamin D Supplemented Adolescents. Metab Syndr Relat Disord. 2018 05; 16(4):197-203.

View in: PubMed
Bouhlal S, Ellefsen KN, Sheskier MB, Singley E, Pirard S, Gorelick DA, Huestis MA, Leggio L. Acute effects of intravenous cocaine administration on serum concentrations of ghrelin, amylin, glucagon-like peptide-1, insulin, leptin and peptide YY and relationships with cardiorespiratory and subjective responses. Drug Alcohol Depend. 2017 11 01; 180:68-75.

View in: PubMed
Qasem RJ, Li J, Tang HM, Pontiggia L, D'mello AP. Maternal protein restriction during pregnancy and lactation alters central leptin signalling, increases food intake, and decreases bone mass in 1 year old rat offspring. Clin Exp Pharmacol Physiol. 2016 Apr; 43(4):494-502.

View in: PubMed
Klein KO, Newfield RS, Hassink SG. Bone maturation along the spectrum from normal weight to obesity: a complex interplay of sex, growth factors and weight gain. J Pediatr Endocrinol Metab. 2016 Mar; 29(3):311-8.

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Saraswathi V, Ramnanan CJ, Wilks AW, Desouza CV, Eller AA, Murali G, Ramalingam R, Milne GL, Coate KC, Edgerton DS. Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice. Metabolism. 2013 Nov; 62(11):1673-85.

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Battula VL, Chen Y, Cabreira Mda G, Ruvolo V, Wang Z, Ma W, Konoplev S, Shpall E, Lyons K, Strunk D, Bueso-Ramos C, Davis RE, Konopleva M, Andreeff M. Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment. Blood. 2013 Jul 18; 122(3):357-66.

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Qasem RJ, Yablonski E, Li J, Tang HM, Pontiggia L, D'mello AP. Elucidation of thrifty features in adult rats exposed to protein restriction during gestation and lactation. Physiol Behav. 2012 Mar 20; 105(5):1182-93.

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Valentino MA, Lin JE, Snook AE, Li P, Kim GW, Marszalowicz G, Magee MS, Hyslop T, Schulz S, Waldman SA. A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. J Clin Invest. 2011 Sep; 121(9):3578-88.

View in: PubMed

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