Pick Disease of the Brain

"Pick Disease of the Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)

Descriptor ID	D020774
MeSH Number(s)	C10.228.140.380.266.299.500 F03.615.400.380.299.500
Concept/Terms	Pick Disease of the Brain Pick Disease of the Brain Brain Atrophy, Circumscribed Lobar Pick Disease Disease, Pick Picks Disease of Brain Lobar Atrophy Of Brain Pick's Disease Disease, Pick's Picks Disease Lobar Atrophy of the Brain Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions Pick Disease Of Brain Lobar Atrophy (Brain) Atrophies, Lobar (Brain) Atrophy, Lobar (Brain) Lobar Atrophies (Brain) Circumscribed Lobar Atrophy of the Brain

Below are MeSH descriptors whose meaning is more general than "Pick Disease of the Brain".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Dementia [C10.228.140.380]
Frontotemporal Lobar Degeneration [C10.228.140.380.266]
Frontotemporal Dementia [C10.228.140.380.266.299]
Pick Disease of the Brain [C10.228.140.380.266.299.500]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Dementia [F03.615.400]
Frontotemporal Lobar Degeneration [F03.615.400.380]
Frontotemporal Dementia [F03.615.400.380.299]
Pick Disease of the Brain [F03.615.400.380.299.500]

Below are MeSH descriptors whose meaning is related to "Pick Disease of the Brain".

Below are MeSH descriptors whose meaning is more specific than "Pick Disease of the Brain".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Pick Disease of the Brain" by people in this website by year, and whether "Pick Disease of the Brain" was a major or minor topic of these publications.

Bar chart showing 10 publications over 7 distinct years, with a maximum of 3 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	2	0	2
2005	0	1	1
2006	3	0	3
2008	0	1	1
2009	0	1	1
2013	1	0	1
2018	0	1	1

Below are the most recent publications written about "Pick Disease of the Brain" by people in Profiles.

Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, Duda JE, Irwin DJ, Wolk D, Elman L, McCluskey L, Chen-Plotkin A, Weintraub D, Arnold SE, Brettschneider J, Lee VM, Trojanowski JQ. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain. 2018 07 01; 141(7):2181-2193.

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Ghosh S, Lippa CF. Clinical Subtypes of Frontotemporal Dementia. Am J Alzheimers Dis Other Demen. 2015 Nov; 30(7):653-61.

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Xie SX, Libon DJ, Wang X, Massimo L, Moore P, Vesely L, Khan A, Chatterjee A, Coslett HB, Hurtig HI, Liang TW, Grossman M. Longitudinal patterns of semantic and episodic memory in frontotemporal lobar degeneration and Alzheimer's disease. J Int Neuropsychol Soc. 2010 Mar; 16(2):278-86.

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Grossman M, Anderson C, Khan A, Avants B, Elman L, McCluskey L. Impaired action knowledge in amyotrophic lateral sclerosis. Neurology. 2008 Oct 28; 71(18):1396-401.

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Shiarli AM, Jennings R, Shi J, Bailey K, Davidson Y, Tian J, Bigio EH, Ghetti B, Murrell JR, Delisle MB, Mirra S, Crain B, Zolo P, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, Halliday G, Mackenzie J, Khan N, Ravid R, Dickson D, Wszolek Z, Iwatsubo T, Pickering-Brown SM, Mann DM. Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease. Neuropathol Appl Neurobiol. 2006 Aug; 32(4):374-87.

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Nagarsheth MH, Viehman A, Lippa SM, Lippa CF. Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease. J Neurol Sci. 2006 May 15; 244(1-2):111-6.

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Murray C, Viehman A, Lippa CF. The corpus callosum in Pick's disease, Alzheimer's disease, and amyotrophic lateral sclerosis: gliosis implies possible clinical consequence. Am J Alzheimers Dis Other Demen. 2006 Jan-Feb; 21(1):37-43.

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Newberg AB, Alavi A. The role of PET imaging in the management of patients with central nervous system disorders. Radiol Clin North Am. 2005 Jan; 43(1):49-65.

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Lippa CF. Synaptophysin immunoreactivity in Pick's disease: comparison with Alzheimer's disease and dementia with Lewy bodies. Am J Alzheimers Dis Other Demen. 2004 Nov-Dec; 19(6):341-4.

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Nee LE, Tierney MC, Lippa CF. Genetic aspects of Alzheimer's disease, Pick's disease, and other dementias. Am J Alzheimers Dis Other Demen. 2004 Jul-Aug; 19(4):219-25.

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