Matrix Metalloproteinases

"Matrix Metalloproteinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of zinc-dependent metalloendopeptidases that is involved in the degradation of EXTRACELLULAR MATRIX components.

Descriptor ID	D020782
MeSH Number(s)	D08.811.277.656.300.480.525 D08.811.277.656.675.374.525
Concept/Terms	Matrix Metalloproteinases Matrix Metalloproteinases Metalloproteinases, Matrix MMPs

Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Metalloendopeptidases [D08.811.277.656.300.480]
Matrix Metalloproteinases [D08.811.277.656.300.480.525]
Metalloproteases [D08.811.277.656.675]
Metalloendopeptidases [D08.811.277.656.675.374]
Matrix Metalloproteinases [D08.811.277.656.675.374.525]

Below are MeSH descriptors whose meaning is related to "Matrix Metalloproteinases".

Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinases".

Matrix Metalloproteinases
Matrix Metalloproteinases, Membrane-Associated
Matrix Metalloproteinases, Secreted

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Matrix Metalloproteinases" by people in this website by year, and whether "Matrix Metalloproteinases" was a major or minor topic of these publications.

Bar chart showing 35 publications over 20 distinct years, with a maximum of 4 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	0	1	1
2003	0	3	3
2004	0	1	1
2005	0	3	3
2006	4	0	4
2007	2	0	2
2008	0	2	2
2009	2	0	2
2010	0	1	1
2011	1	1	2
2012	0	1	1
2013	0	1	1
2014	2	1	3
2016	1	0	1
2017	0	1	1
2018	0	1	1
2019	2	0	2
2020	1	1	2
2022	0	1	1

Below are the most recent publications written about "Matrix Metalloproteinases" by people in Profiles.

MacDonald WW, Swaminathan SS, Heo JY, Castillejos A, Hsueh J, Liu BJ, Jo D, Du A, Lee H, Kang MH, Rhee DJ. Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2022 06 01; 63(6):8.

View in: PubMed
Gelbard MK, Rosenbloom J. Fibroproliferative disorders and diabetes: Understanding the pathophysiologic relationship between Peyronie's disease, Dupuytren disease and diabetes. Endocrinol Diabetes Metab. 2021 04; 4(2):e00195.

View in: PubMed
Heo JY, Ooi YH, Rhee DJ. Effect of prostaglandin analogs: Latanoprost, bimatoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human trabecular meshwork endothelial cells. Exp Eye Res. 2020 05; 194:108019.

View in: PubMed
Summer R, Krishna R, Schriner D, Cuevas-Mora K, Sales D, Para R, Roman J, Nieweld C, Gochuico BR, Romero F. Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome. Orphanet J Rare Dis. 2019 07 04; 14(1):162.

View in: PubMed
Cecen B, Keles D, Oktay G, Kozaci LD. Effects of simvastatin on matrix metalloproteinase regulation in IL-1?-induced SW1353 cells. Chem Biol Interact. 2019 Sep 01; 310:108730.

View in: PubMed
Bouris P, Manou D, Sopaki-Valalaki A, Kolokotroni A, Moustakas A, Kapoor A, Iozzo RV, Karamanos NK, Theocharis AD. Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling. Matrix Biol. 2018 12; 74:35-51.

View in: PubMed
Sharma P, Yi R, Nayak AP, Wang N, Tang F, Knight MJ, Pan S, Oliver B, Deshpande DA. Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice. Sci Rep. 2017 04 11; 7:46166.

View in: PubMed
Garro A, Chodobski A, Szmydynger-Chodobska J, Shan R, Bialo SR, Bennett J, Quayle K, Rewers A, Schunk JE, Casper TC, Kuppermann N, Glaser N. Circulating matrix metalloproteinases in children with diabetic ketoacidosis. Pediatr Diabetes. 2017 03; 18(2):95-102.

View in: PubMed
Theocharis AD, Gialeli C, Bouris P, Giannopoulou E, Skandalis SS, Aletras AJ, Iozzo RV, Karamanos NK. Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer. FEBS J. 2014 Nov; 281(22):5023-42.

View in: PubMed
Ahmed FZ, Khattar RS, Zaidi AM, Neyses L, Oceandy D, Mamas M. Pacing-induced cardiomyopathy: pathophysiological insights through matrix metalloproteinases. Heart Fail Rev. 2014 Sep; 19(5):669-80.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement