Amino Acid Motifs

"Amino Acid Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Three-dimensional protein structural elements that are composed of a combination of secondary structures. They include HELIX-LOOP-HELIX MOTIFS and ZINC FINGERS. Motifs are typically the most conserved regions of PROTEIN DOMAINS and are critical for domain function. However, the same motif may occur in proteins or enzymes with different functions.

Descriptor ID	D020816
MeSH Number(s)	G02.111.570.820.709.275.500 G02.111.570.820.709.600.500
Concept/Terms	Amino Acid Motifs Amino Acid Motifs Amino Acid Motif Motif, Amino Acid Motifs, Amino Acid Protein Motifs Motif, Protein Motifs, Protein Protein Motif Protein Structure, Supersecondary Protein Structure, Supersecondary Protein Structures, Supersecondary Supersecondary Protein Structures Supersecondary Protein Structure

Below are MeSH descriptors whose meaning is more general than "Amino Acid Motifs".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Amino Acid Motifs [G02.111.570.820.709.275.500]
Protein Structure, Secondary [G02.111.570.820.709.600]
Amino Acid Motifs [G02.111.570.820.709.600.500]

Below are MeSH descriptors whose meaning is related to "Amino Acid Motifs".

Below are MeSH descriptors whose meaning is more specific than "Amino Acid Motifs".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Amino Acid Motifs" by people in this website by year, and whether "Amino Acid Motifs" was a major or minor topic of these publications.

Bar chart showing 119 publications over 20 distinct years, with a maximum of 16 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	2	0	2
2000	0	4	4
2001	0	9	9
2002	0	6	6
2003	0	10	10
2004	2	14	16
2005	0	9	9
2006	0	7	7
2007	0	8	8
2008	0	6	6
2009	0	6	6
2010	1	6	7
2011	0	3	3
2012	0	5	5
2013	0	4	4
2014	0	6	6
2015	1	2	3
2016	0	2	2
2019	0	4	4
2020	0	2	2

Below are the most recent publications written about "Amino Acid Motifs" by people in Profiles.

Koirala S, Klein J, Zheng Y, Glenn NO, Eisemann T, Fon Tacer K, Miller DJ, Kulak O, Lu M, Finkelstein DB, Neale G, Tillman H, Vogel P, Strand DW, Lum L, Brautigam CA, Pascal JM, Clements WK, Potts PR. Tissue-Specific Regulation of the Wnt/?-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020 07 21; 32(3):107922.

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Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation. J Biol Chem. 2020 03 06; 295(10):3316-3329.

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Eisemann T, Langelier MF, Pascal JM. Structural and functional analysis of parameters governing tankyrase-1 interaction with telomeric repeat-binding factor 1 and GDP-mannose 4,6-dehydratase. J Biol Chem. 2019 10 04; 294(40):14574-14590.

View in: PubMed
Haseeb A, Lefebvre V. The SOXE transcription factors-SOX8, SOX9?and SOX10-share a bi-partite transactivation mechanism. Nucleic Acids Res. 2019 07 26; 47(13):6917-6931.

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Velagapudi UK, Langelier MF, Delgado-Martin C, Diolaiti ME, Bakker S, Ashworth A, Patel BA, Shao X, Pascal JM, Talele TT. Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J Med Chem. 2019 06 13; 62(11):5330-5357.

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Mercier R, Wolmarans A, Schubert J, Neuweiler H, Johnson JL, LaPointe P. The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation. Nat Commun. 2019 03 20; 10(1):1273.

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Park JM, Ponder CM, Sewell BT, Benedik MJ. Residue Y70 of the Nitrilase Cyanide Dihydratase from Bacillus pumilus Is Critical for Formation and Activity of the Spiral Oligomer. J Microbiol Biotechnol. 2016 Dec 28; 26(12):2179-2183.

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Deng W, Wang C, Zhang Y, Xu Y, Zhang S, Liu Z, Xue Y. GPS-PAIL: prediction of lysine acetyltransferase-specific modification sites from protein sequences. Sci Rep. 2016 12 22; 6:39787.

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Thomas LR, Foshage AM, Weissmiller AM, Popay TM, Grieb BC, Qualls SJ, Ng V, Carboneau B, Lorey S, Eischen CM, Tansey WP. Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif. Oncogene. 2016 07 07; 35(27):3613-8.

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Naghdi S, V?rnai P, Hajn?czky G. Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis. Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41):E5590-9.

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