rap1 GTP-Binding Proteins
"rap1 GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetically related subfamily of RAP GTP-BINDING PROTEINS that share homology with RAS PROTEINS. They bind to Ras effectors but do not activate them, therefore they may antagonize the effects of RAS PROTEINS. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020827
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.475.100 D12.644.360.525.475.100 D12.776.157.325.515.475.100 D12.776.476.525.475.100
|
| Concept/Terms |
rap1 GTP-Binding Protein- rap1 GTP-Binding Protein
- GTP-Binding Protein, rap1
- rap1 GTP Binding Protein
- rap1A Protein
- smg p21 GTP-Binding Protein
- smg p21 GTP Binding Protein
- smg p21A Protein
- p21A Protein, smg
- rap1A GTP-Binding Protein
- GTP-Binding Protein, rap1A
- rap1A GTP Binding Protein
- Krev-1 GTP-Binding Protein
- GTP-Binding Protein, Krev-1
- Krev 1 GTP Binding Protein
- SMG p21A GTP-Binding Protein
- SMG p21A GTP Binding Protein
- Krev-1 Protein
- Krev 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "rap1 GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "rap1 GTP-Binding Proteins".
This graph shows the total number of publications written about "rap1 GTP-Binding Proteins" by people in this website by year, and whether "rap1 GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "rap1 GTP-Binding Proteins" by people in Profiles.
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Dong X, Tang W, Stopenski S, Brose MS, Korch C, Meinkoth JL. RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells. Endocr Relat Cancer. 2012 Aug; 19(4):575-88.
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Stefanini L, Boulaftali Y, Ouellette TD, Holinstat M, Désiré L, Leblond B, Andre P, Conley PB, Bergmeier W. Rap1-Rac1 circuits potentiate platelet activation. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):434-41.
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Holinstat M, Preininger AM, Milne SB, Hudson WJ, Brown HA, Hamm HE. Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates. Mol Pharmacol. 2009 Aug; 76(2):301-13.
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Goldfinger LE, Ptak C, Jeffery ED, Shabanowitz J, Han J, Haling JR, Sherman NE, Fox JW, Hunt DF, Ginsberg MH. An experimentally derived database of candidate Ras-interacting proteins. J Proteome Res. 2007 May; 6(5):1806-11.
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Holinstat M, Voss B, Bilodeau ML, Hamm HE. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway. Mol Pharmacol. 2007 Mar; 71(3):686-94.
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Lobell RB, Liu D, Buser CA, Davide JP, DePuy E, Hamilton K, Koblan KS, Lee Y, Mosser S, Motzel SL, Abbruzzese JL, Fuchs CS, Rowinsky EK, Rubin EH, Sharma S, Deutsch PJ, Mazina KE, Morrison BW, Wildonger L, Yao SL, Kohl NE. Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I. Mol Cancer Ther. 2002 Jul; 1(9):747-58.