Small Ubiquitin-Related Modifier Proteins
"Small Ubiquitin-Related Modifier Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of structurally related proteins of 12-20 kDa in size. They covalently modify specific proteins in a manner analogous to UBIQUITIN.
Descriptor ID |
D025841
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MeSH Number(s) |
D12.776.947.249
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Concept/Terms |
Small Ubiquitin-Related Modifier Proteins- Small Ubiquitin-Related Modifier Proteins
- Small Ubiquitin Related Modifier Proteins
- Ubiquitin-Related Modifier Protein, Small
- Ubiquitin Related Modifier Protein, Small
- Sentrins
- Sentrin Proteins
- SUMO Proteins
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Below are MeSH descriptors whose meaning is more general than "Small Ubiquitin-Related Modifier Proteins".
Below are MeSH descriptors whose meaning is more specific than "Small Ubiquitin-Related Modifier Proteins".
This graph shows the total number of publications written about "Small Ubiquitin-Related Modifier Proteins" by people in this website by year, and whether "Small Ubiquitin-Related Modifier Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
2007 | 2 | 0 | 2 |
2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Small Ubiquitin-Related Modifier Proteins" by people in Profiles.
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Xiong L, Chen XL, Silver HR, Ahmed NT, Johnson ES. Deficient SUMO attachment to Flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 microm circle plasmid. Mol Biol Cell. 2009 Feb; 20(4):1241-51.
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Ivanov AV, Peng H, Yurchenko V, Yap KL, Negorev DG, Schultz DC, Psulkowski E, Fredericks WJ, White DE, Maul GG, Sadofsky MJ, Zhou MM, Rauscher FJ. PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. Mol Cell. 2007 Dec 14; 28(5):823-37.
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Huang RY, Kowalski D, Minderman H, Gandhi N, Johnson ES. Small ubiquitin-related modifier pathway is a major determinant of doxorubicin cytotoxicity in Saccharomyces cerevisiae. Cancer Res. 2007 Jan 15; 67(2):765-72.
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Reindle A, Belichenko I, Bylebyl GR, Chen XL, Gandhi N, Johnson ES. Multiple domains in Siz SUMO ligases contribute to substrate selectivity. J Cell Sci. 2006 Nov 15; 119(Pt 22):4749-57.
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Johnson ES. Protein modification by SUMO. Annu Rev Biochem. 2004; 73:355-82.
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Chan HY, Warrick JM, Andriola I, Merry D, Bonini NM. Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Hum Mol Genet. 2002 Nov 1; 11(23):2895-904.