"Serum Response Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.
| Descriptor ID |
D026362
|
| MeSH Number(s) |
D12.776.260.400.249.875 D12.776.930.397.875
|
| Concept/Terms |
Serum Response Factor- Serum Response Factor
- Response Factor, Serum
- Transcription Factor SRF
- c-fos Serum Response Factor
- c fos Serum Response Factor
|
Below are MeSH descriptors whose meaning is more general than "Serum Response Factor".
Below are MeSH descriptors whose meaning is more specific than "Serum Response Factor".
This graph shows the total number of publications written about "Serum Response Factor" by people in this website by year, and whether "Serum Response Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serum Response Factor" by people in Profiles.
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Bhattacharyya R, Wedegaertner PB. Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding. J Biol Chem. 2000 May 19; 275(20):14992-9.
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Westwick JK, Lee RJ, Lambert QT, Symons M, Pestell RG, Der CJ, Whitehead IP. Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun. J Biol Chem. 1998 Jul 3; 273(27):16739-47.
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Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG, Der CJ. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol Cell Biol. 1997 Mar; 17(3):1324-35.