Barbara Schick

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address1025 Walnut Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Schick BP. Serglycin proteoglycan deletion in mouse platelets: physiological effects and their implications for platelet contributions to thrombosis, inflammation, atherosclerosis, and metastasis. Prog Mol Biol Transl Sci. 2010; 93:235-87. PMID: 20807648.
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    2. Woulfe DS, Lilliendahl JK, August S, Rauova L, Kowalska MA, Abrink M, Pejler G, White JG, Schick BP. Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice. Blood. 2008 Apr 01; 111(7):3458-67. PMID: 18094327.
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    3. Schick BP, Maslow D, Moshinski A, San Antonio JD. Novel concatameric heparin-binding peptides reverse heparin and low-molecular-weight heparin anticoagulant activities in patient plasma in vitro and in rats in vivo. Blood. 2004 Feb 15; 103(4):1356-63. PMID: 14576044.
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    4. Castronuevo P, Thornton MA, McCarthy LE, Klimas J, Schick BP. DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial cells. J Biol Chem. 2003 Dec 05; 278(49):48704-12. PMID: 14506241.
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    5. Schick BP, Ho HC, Brodbeck KC, Wrigley CW, Klimas J. Serglycin proteoglycan expression and synthesis in embryonic stem cells. Biochim Biophys Acta. 2003 Feb 17; 1593(2-3):259-67. PMID: 12581870.
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    6. Keith Ho HC, McGrath KE, Brodbeck KC, Palis J, Schick BP. Serglycin proteoglycan synthesis in the murine uterine decidua and early embryo. Biol Reprod. 2001 Jun; 64(6):1667-76. PMID: 11369593.
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    7. Schick BP, Petrushina I, Brodbeck KC, Castronuevo P. Promoter regulatory elements and DNase I-hypersensitive sites involved in serglycin proteoglycan gene expression in human erythroleukemia, CHRF 288-11, and HL-60 cells. J Biol Chem. 2001 Jul 06; 276(27):24726-35. PMID: 11333275.
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    8. Schick BP, Gradowski JF, San Antonio JD, Martinez J. Novel design of peptides to reverse the anticoagulant activities of heparin and other glycosaminoglycans. Thromb Haemost. 2001 Mar; 85(3):482-7. PMID: 11307819.
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    9. Schick BP, Gradowski JF, San Antonio JD. Synthesis, secretion, and subcellular localization of serglycin proteoglycan in human endothelial cells. Blood. 2001 Jan 15; 97(2):449-58. PMID: 11154222.
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    10. Verrecchio A, Germann MW, Schick BP, Kung B, Twardowski T, San Antonio JD. Design of peptides with high affinities for heparin and endothelial cell proteoglycans. J Biol Chem. 2000 Mar 17; 275(11):7701-7. PMID: 10713081.
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    11. Schick BP, Pestina TI, San Antonio JD, Stenberg PE, Jackson CW. Decreased serglycin proteoglycan size is associated with the platelet alpha granule storage defect in Wistar Furth hereditary macrothrombocytopenic rats. Serglycin binding affinity to type I collagen is unaltered. J Cell Physiol. 1997 Jul; 172(1):87-93. PMID: 9207929.
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    12. Ludlow LB, Schick BP, Budarf ML, Driscoll DA, Zackai EH, Cohen A, Konkle BA. Identification of a mutation in a GATA binding site of the platelet glycoprotein Ibbeta promoter resulting in the Bernard-Soulier syndrome. J Biol Chem. 1996 Sep 06; 271(36):22076-80. PMID: 8703016.
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    13. Schick BP. Regulation of expression of megakaryocyte and platelet proteoglycans. Stem Cells. 1996; 14 Suppl 1:220-31. PMID: 11012225.
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    14. Schick BP, Jacoby JA. Serglycin and betaglycan proteoglycans are expressed in the megakaryocytic cell line CHRF 288-11 and normal human megakaryocytes. J Cell Physiol. 1995 Oct; 165(1):96-106. PMID: 7559813.
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    15. Schick BP, Eras J. Proteoglycans partially co-purify with RNA in TRI Reagent and can be transferred to filters by northern blotting. Biotechniques. 1995 Apr; 18(4):574-6, 578. PMID: 7541213.
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    16. Schick BP, Tang RP, Jacoby JA. Changes in protein sulfation in human erythroleukemia (HEL), CHRF-288-11, and K562 cells following treatment with dimethyl sulfoxide or phorbol 12-myristate 13-acetate. Arch Biochem Biophys. 1995 Feb 20; 317(1):191-200. PMID: 7872784.
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    17. Schick BP, Eras JL, Mintz PS. Phosphorothioate oligonucleotides cause degradation of secretory but not intracellular serglycin proteoglycan core protein in a sequence-independent manner in human megakaryocytic tumor cells. Antisense Res Dev. 1995; 5(1):59-65. PMID: 7613073.
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    18. Schick BP. Hope for treatment of thrombocytopenia. N Engl J Med. 1994 Sep 29; 331(13):875-6. PMID: 8078536.
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    19. Schick BP, Jacoby JA. Sulfation of guinea pig megakaryocyte and platelet proteins. J Cell Physiol. 1994 May; 159(2):356-64. PMID: 8163574.
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    20. Schick BP, Thornton RD. Expression of mRNA for serglycin core protein and other platelet alpha granule proteins is increased in human erythroleukemia cells by phorbol myristate acetate. Leukemia. 1993 Dec; 7(12):1955-9. PMID: 7504770.
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    21. Schick BP, Senkowski-Richardson S. Proteoglycan synthesis in human erythroleukaemia (HEL) cells. Biochem J. 1992 Mar 15; 282 ( Pt 3):651-8. PMID: 1372801.
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    22. Schick BP. Effect of diet-induced hypercholesterolemia on proteoglycan metabolism in guinea pig megakaryocytes and platelets. Arterioscler Thromb. 1991 Jan-Feb; 11(1):191-7. PMID: 1987997.
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    23. Schick BP. Synthesis of proteins from [35S]methionine by guinea pig megakaryocytes in vivo and time course of appearance of newly synthesized proteins in platelets. Blood. 1990 Sep 01; 76(5):887-91. PMID: 2393715.
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    24. Schick BP. Proteoglycans in megakaryocyte development. Prog Clin Biol Res. 1990; 356:93-104. PMID: 2217453.
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    25. Schick PK, Schick BP, Williams-Gartner K. Characterization of guinea pig megakaryocyte subpopulations at different phases of maturation prepared with a Celsep separation system. Blood. 1989 May 15; 73(7):1801-8. PMID: 2713506.
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