Thomas Jefferson University

David Harris

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address833 Chestnut Street
Philadelphia PA 19107
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    R01CA048085     (HARRIS, DAVID T)Jul 15, 1988 - Jun 30, 1994
    NIH
    ANALYSIS OF A NATURAL KILLER CELL TARGET CELL ANTIGEN
    Role: Principal Investigator
    R01AG038021     (HARRIS, DAVID THOMAS)Sep 1, 2010 - Aug 31, 2015
    NIH
    Role of Extrinsic and Intrinsic Factors Responsible for Aging of Immune System
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Choudhery MS, Arif T, Mahmood R, Harris DT. Stem Cell-Based Acellular Therapy: Insight into Biogenesis, Bioengineering and Therapeutic Applications of Exosomes. Biomolecules. 2024 Jul 03; 14(7). PMID: 39062506.
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    2. Choudhery MS, Arif T, Mahmood R, Harris DT. CAR-T-Cell-Based Cancer Immunotherapies: Potentials, Limitations, and Future Prospects. J Clin Med. 2024 May 29; 13(11). PMID: 38892913.
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    3. Simchick G, Zhao R, Yuan Q, Ghasabeh MA, Ruschke S, Karampinos DC, Harris DT, do Vale Souza R, Mattison RJ, Jeng MR, Pedrosa I, Kamel IR, Vasanawala S, Yokoo T, Reeder SB, Hernando D. Practical Application of Multivendor MRI-Based R2* Mapping for Liver Iron Quantification at 1.5?T and 3.0?T. J Magn Reson Imaging. 2024 Apr 25. PMID: 38662618.
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    4. Harris DT, Ingraham N, Badowski M. Comparison of Manual versus Automated SARS-CoV-2 Rapid Antigen Testing in Asymptomatic Individuals. J Clin Med. 2023 Nov 17; 12(22). PMID: 38002757.
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    5. Shamim AMKM, Panagiotopoulos N, Spahic A, Harris DT, Rold?n-Alzate A, Wieben O, Reeder SB, Oechtering TH, Johnson KM. Fat mitigation strategies to improve image quality of radial 4D flow MRI in obese subjects. Magn Reson Med. 2023 Apr 10. PMID: 37036023.
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    6. Hernando D, Zhao R, Yuan Q, Aliyari Ghasabeh M, Ruschke S, Miao X, Karampinos DC, Mao L, Harris DT, Mattison RJ, Jeng MR, Pedrosa I, Kamel IR, Vasanawala S, Yokoo T, Reeder SB. Multicenter Reproducibility of Liver Iron Quantification with 1.5-T and 3.0-T MRI. Radiology. 2023 Feb; 306(2):e213256. PMID: 36194113.
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    7. Choudhery MS, Mahmood R, Harris DT, Ahmad FJ. Minimum criteria for defining induced mesenchymal stem cells. Cell Biol Int. 2022 Jun; 46(6):986-989. PMID: 35293653.
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    8. Muise A, White L, Badowski M, Harris DT. Analysis of High-Throughput Processing Methods for Peripheral Blood Cell Isolation. Biopreserv Biobank. 2022 06; 20(3):302-305. PMID: 35085446.
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    9. Zhao R, Hernando D, Harris DT, Hinshaw LA, Li K, Ananthakrishnan L, Bashir MR, Duan X, Ghasabeh MA, Kamel IR, Lowry C, Mahesh M, Marin D, Miller J, Pickhardt PJ, Shaffer J, Yokoo T, Brittain JH, Reeder SB. Multisite multivendor validation of a quantitative MRI and CT compatible fat phantom. Med Phys. 2021 Aug; 48(8):4375-4386. PMID: 34105167.
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    10. Harris DT, Badowski M, Jernigan B, Sprissler R, Edwards T, Cohen R, Paul S, Merchant N, Weinkauf CC, Bime C, Erickson HE, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, El Aini T, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Knox K, Mosier J, Spier C, Dake MD. SARS-CoV-2 Rapid Antigen Testing of Symptomatic and Asymptomatic Individuals on the University of Arizona Campus. Biomedicines. 2021 May 12; 9(5). PMID: 34066047.
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    11. Betancourt WQ, Schmitz BW, Innes GK, Prasek SM, Pogreba Brown KM, Stark ER, Foster AR, Sprissler RS, Harris DT, Sherchan SP, Gerba CP, Pepper IL. COVID-19 containment on a college campus via wastewater-based epidemiology, targeted clinical testing and an intervention. Sci Total Environ. 2021 Jul 20; 779:146408. PMID: 33743467.
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    12. Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, Erickson HL, Knox K, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, El Aini T, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Capaldi AP, Spier CM, Dake MD, Edwards T, Kaplan ME, Scott SJ, Hypes C, Mosier J, Harris DT, LaFleur BJ, Sprissler R, Nikolich-?ugich J, Bhattacharya D. Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity. Immunity. 2020 11 17; 53(5):925-933.e4. PMID: 33129373.
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    13. Choudhery MS, Harris DT. Stem cell therapy for COVID-19: Possibilities and challenges. Cell Biol Int. 2020 Nov; 44(11):2182-2191. PMID: 32767687.
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    14. Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, Erickson HL, Knox K, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, Aini TE, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Capaldi AP, Spier CM, Dake MD, Edwards T, Kaplan ME, Scott SJ, Hypes C, Mosier J, Harris DT, LaFleur BJ, Sprissler R, Nikolich-?ugich J, Bhattacharya D. Detection, prevalence, and duration of humoral responses to SARS-CoV-2 under conditions of limited population exposure. medRxiv. 2020 Aug 15. PMID: 32817969.
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    15. Valori V, Tus K, Laukaitis C, Harris DT, LeBeau L, Maggert KA. Human rDNA copy number is unstable in metastatic breast cancers. Epigenetics. 2020 Jan - Feb; 15(1-2):85-106. PMID: 31352858.
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    16. Badowski MS, Muise A, Harris DT. Long-Term Biobanking of Intact Tissue from Lipoaspirate. J Clin Med. 2019 Mar 08; 8(3). PMID: 30857129.
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    17. Harris DT, Israel S. What will Become of the Taxpayer Investment in Public Cord Blood Stem Cell Banking? Curr Stem Cell Res Ther. 2019; 14(4):367-372. PMID: 30806326.
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    18. Harris DT. Biobanking and Regenerative Medicine: An Overview. J Clin Med. 2018 May 31; 7(6). PMID: 29857481.
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    19. Pandey AC, Lancaster JJ, Harris DT, Goldman S, Juneman E. Cellular Therapeutics for Heart Failure: Focus on Mesenchymal Stem Cells. Stem Cells Int. 2017; 2017:9640108. PMID: 29391871.
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    20. Harris DT. Banking of Adipose- and Cord Tissue-Derived Stem Cells: Technical and Regulatory Issues. Adv Exp Med Biol. 2016; 951:147-154. PMID: 27837561.
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    21. Harris DT, Kallman BR, Mullaney BC, Scott K. Representations of Taste Modality in the Drosophila Brain. Neuron. 2015 Jun 17; 86(6):1449-60. PMID: 26051423.
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    22. Choudhery MS, Badowski M, Muise A, Pierce J, Harris DT. Subcutaneous Adipose Tissue-Derived Stem Cell Utility Is Independent of Anatomical Harvest Site. Biores Open Access. 2015; 4(1):131-45. PMID: 26309790.
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    23. Corenblum MJ, Flores AJ, Badowski M, Harris DT, Madhavan L. Systemic human CD34(+) cells populate the brain and activate host mechanisms to counteract nigrostriatal degeneration. Regen Med. 2015; 10(5):563-77. PMID: 26237701.
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    24. Choudhery MS, Badowski M, Muise A, Harris DT. Effect of mild heat stress on the proliferative and differentiative ability of human mesenchymal stromal cells. Cytotherapy. 2015 Apr; 17(4):359-68. PMID: 25536863.
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    25. Choudhery MS, Harris DT. Cryopreservation can be used as an anti-aging strategy. Cytotherapy. 2014 Dec; 16(12):1771-3. PMID: 25304665.
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    26. Badowski M, Muise A, Harris DT. Mixed effects of long-term frozen storage on cord tissue stem cells. Cytotherapy. 2014 Sep; 16(9):1313-21. PMID: 25108655.
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    27. Li H, Feng Z, Tsang TC, Tang T, Jia X, He X, Pennington ME, Badowski MS, Liu AK, Chen D, Harris DT, Martinez J, Meade-Tollin LC. Fusion of HepG2 cells with mesenchymal stem cells increases cancer-associated and malignant properties: an in vivo metastasis model. Oncol Rep. 2014 Aug; 32(2):539-47. PMID: 24926698.
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    28. Badowski M, Shultz C, Harris DT. WITHDRAWN: Effect of anti-coagulant choice on cord blood processing results. Cytotherapy. 2014 Jun 11. PMID: 24927714.
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    29. Badowski M, Shultz CL, Eason Y, Ahmad N, Harris DT. The influence of intrinsic and extrinsic factors on immune system aging. Immunobiology. 2014 Jun; 219(6):482-5. PMID: 24661721.
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    30. Harris DT. Stem Cell Banking for Regenerative and Personalized Medicine. Biomedicines. 2014 Feb 26; 2(1):50-79. PMID: 28548060.
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    31. Choudhery MS, Badowski M, Muise A, Pierce J, Harris DT. Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation. J Transl Med. 2014 Jan 07; 12:8. PMID: 24397850.
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    32. Choudhery MS, Badowski M, Muise A, Pierce J, Harris DT. Cryopreservation of whole adipose tissue for future use in regenerative medicine. J Surg Res. 2014 Mar; 187(1):24-35. PMID: 24268882.
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    33. Harris DT, Badowski M. Long term human reconstitution and immune aging in NOD-Rag (-)-? chain (-) mice. Immunobiology. 2014 Feb; 219(2):131-7. PMID: 24094417.
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    34. Choudhery MS, Badowski M, Muise A, Harris DT. Utility of cryopreserved umbilical cord tissue for regenerative medicine. Curr Stem Cell Res Ther. 2013 Sep; 8(5):370-80. PMID: 23755729.
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    35. Harris DT. Umbilical cord tissue mesenchymal stem cells: characterization and clinical applications. Curr Stem Cell Res Ther. 2013 Sep; 8(5):394-9. PMID: 23895058.
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    36. Choudhery MS, Badowski M, Muise A, Harris DT. Comparison of human mesenchymal stem cells derived from adipose and cord tissue. Cytotherapy. 2013 Mar; 15(3):330-43. PMID: 23318344.
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    37. Harris DT. Is volume the only factor that impacts cord blood processing efficiency? Cytotherapy. 2012 Sep; 14(8):1022-3. PMID: 22624698.
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    38. Harris DT, Hilgaertner J, Simonson C, Ablin RJ, Badowski M. Cell-based therapy for epithelial wounds. Cytotherapy. 2012 Aug; 14(7):802-10. PMID: 22458955.
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    39. Harris DT. Alterations in target cell membrane phospholipids alter T cell but not NK cell killing. Immunobiology. 2013 Jan; 218(1):21-7. PMID: 22349517.
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    40. Badowski MS, Harris DT. Collection, processing, and banking of umbilical cord blood stem cells for transplantation and regenerative medicine. Methods Mol Biol. 2012; 879:279-90. PMID: 22610565.
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    41. Harris DT. Optimizing cord blood sample cryopreservation. Cytotherapy. 2012 Mar; 14(3):359-65. PMID: 22175912.
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    42. Harris DT. Changes in plasma membrane phospholipids inhibit antibody-mediated lysis. Biochem Biophys Res Commun. 2012 Jan 06; 417(1):231-6. PMID: 22142842.
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    43. Harris DT, Horvitz HR. MAB-10/NAB acts with LIN-29/EGR to regulate terminal differentiation and the transition from larva to adult in C. elegans. Development. 2011 Sep; 138(18):4051-62. PMID: 21862562.
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    44. Hurschler BA, Harris DT, Grosshans H. The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans. Nucleic Acids Res. 2011 Jul; 39(13):5647-57. PMID: 21415013.
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    45. Hilgaertner JW, He X, Camacho D, Badowski M, Witten M, Harris DT. The influence of hydrocarbon composition and exposure conditions on jet fuel-induced immunotoxicity. Toxicol Ind Health. 2011 Nov; 27(10):887-98. PMID: 21402657.
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    46. Ahmad N, Mehta R, Harris DT. HIV-1 replication and gene expression occur at higher levels in neonatal blood naive and memory T-lymphocytes compared with adult blood cells. Virology. 2011 Apr 25; 413(1):39-46. PMID: 21353282.
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    47. Nietfeld JJ, Harris DT. Cost-effectiveness of private umbilical cord blood banking. Obstet Gynecol. 2010 May; 115(5):1090. PMID: 20410795.
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    48. Sundaravaradan V, Mehta R, Harris DT, Zack JA, Ahmad N. Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells. Virology. 2010 Apr 25; 400(1):32-43. PMID: 20138641.
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    49. Harris DT. Non-haematological uses of cord blood stem cells. Br J Haematol. 2009 Oct; 147(2):177-84. PMID: 19796266.
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    50. Badowski MS, Zhang T, Tsang TC, Harris DT. Chimeric antigen receptors for stem cell based immunotherapy. J Exp Ther Oncol. 2009; 8(1):53-63. PMID: 19827271.
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    51. Wellensiek BP, Ramakrishnan R, Sundaravaradan V, Mehta R, Harris DT, Ahmad N. Differential HIV-1 integration targets more actively transcribed host genes in neonatal than adult blood mononuclear cells. Virology. 2009 Mar 01; 385(1):28-38. PMID: 19100594.
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    52. Harris DT. Cord blood stem cells: worth the investment. Nat Rev Cancer. 2008 Oct; 8(10):823; author reply 823. PMID: 18813324.
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    53. Harris DT. Cord blood stem cells: a review of potential neurological applications. Stem Cell Rev. 2008 Dec; 4(4):269-74. PMID: 18679834.
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    54. Harris DT, Rogers I. Umbilical cord blood: a unique source of pluripotent stem cells for regenerative medicine. Curr Stem Cell Res Ther. 2007 Dec; 2(4):301-9. PMID: 18220914.
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    55. Andrus MB, Christiansen MA, Hicken EJ, Gainer MJ, Bedke DK, Harper KC, Mikkelson SR, Dodson DS, Harris DT. Phase-transfer-catalyzed asymmetric acylimidazole alkylation. Org Lett. 2007 Nov 08; 9(23):4865-8. PMID: 17944480.
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    56. Davis AH, Tsang TC, Harris DT. Direct sequencing is more accurate and feasible in detecting single nucleotide polymorphisms than RFLP: using human vascular endothelial growth factor gene as a model. Biol Res Nurs. 2007 Oct; 9(2):170-8. PMID: 17909169.
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    57. Harris DT, Badowski M, Ahmad N, Gaballa MA. The potential of cord blood stem cells for use in regenerative medicine. Expert Opin Biol Ther. 2007 Sep; 7(9):1311-22. PMID: 17727322.
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    58. Harris DT, Sakiestewa D, Titone D, Witten M. JP-8 jet fuel exposure rapidly induces high levels of IL-10 and PGE2 secretion and is correlated with loss of immune function. Toxicol Ind Health. 2007 May; 23(4):223-30. PMID: 18429382.
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    59. Cohen-Barak O, Erickson DT, Badowski MS, Fuchs DA, Klassen CL, Harris DT, Brilliant MH. Stem cell transplantation demonstrates that Sox6 represses epsilon y globin expression in definitive erythropoiesis of adult mice. Exp Hematol. 2007 Mar; 35(3):358-67. PMID: 17309816.
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    60. Lister J, Gryn JF, McQueen KL, Harris DT, Rossetti JM, Shadduck RK. Multiple unit HLA-unmatched sex-mismatched umbilical cord blood transplantation for advanced hematological malignancy. Stem Cells Dev. 2007 Feb; 16(1):177-86. PMID: 17348813.
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    61. Dammeyer P, Jaramillo MC, Pipes BL, Badowski MS, Tsang TC, Harris DT. Heat-inducible amplifier vector for high-level expression of granulocyte-macrophage colony-stimulating factor. Int J Hyperthermia. 2006 Aug; 22(5):407-19. PMID: 16891243.
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    62. Sundaravaradan V, Saxena SK, Ramakrishnan R, Yedavalli VR, Harris DT, Ahmad N. Differential HIV-1 replication in neonatal and adult blood mononuclear cells is influenced at the level of HIV-1 gene expression. Proc Natl Acad Sci U S A. 2006 Aug 01; 103(31):11701-6. PMID: 16868088.
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    63. Pipes BL, Tsang T, Peng SX, Fiederlein R, Graham M, Harris DT. Telomere length changes after umbilical cord blood transplant. Transfusion. 2006 Jun; 46(6):1038-43. PMID: 16734822.
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    64. He X, Gonzalez V, Tsang A, Thompson J, Tsang TC, Harris DT. Differential gene expression profiling of CD34+ CD133+ umbilical cord blood hematopoietic stem progenitor cells. Stem Cells Dev. 2005 Apr; 14(2):188-98. PMID: 15910245.
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    65. He X, Tsang TC, Zhang T, Luo P, Harris DT. Antigen epitope-expressing cytokines for DNA immunization. Vaccine. 2005 Mar 14; 23(16):1966-72. PMID: 15734069.
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    66. He X, Luo P, Tsang TC, Zhang T, Harris DT. Immuno-gene therapy of melanoma by tumor antigen epitope modified IFN-gamma. Cancer Immunol Immunother. 2005 Aug; 54(8):741-9. PMID: 15726359.
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    67. He X, Tsang TC, Pipes BL, Ablin RJ, Harris DT. A stem cell fusion model of carcinogenesis. J Exp Ther Oncol. 2005; 5(2):101-9. PMID: 16471036.
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    68. Lebsack TW, Kreulen C, Deever DB, Harris DT, Witten ML. Substance P effects on developing thymocytes in hindlimb unloaded rats. Aviat Space Environ Med. 2005 Jan; 76(1):11-8. PMID: 15672981.
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    69. Pipes BL, Vasanwala FH, Tsang TC, Zhang T, Luo P, Harris DT. Brief heat shock increases stable integration of lipid-mediated DNA transfections. Biotechniques. 2005 Jan; 38(1):48, 50, 52. PMID: 15679084.
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    70. Zhang T, He X, Tsang TC, Harris DT. Transgenic TCR expression: comparison of single chain with full-length receptor constructs for T-cell function. Cancer Gene Ther. 2004 Jul; 11(7):487-96. PMID: 15153936.
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    71. Laurencon A, Orme CM, Peters HK, Boulton CL, Vladar EK, Langley SA, Bakis EP, Harris DT, Harris NJ, Wayson SM, Hawley RS, Burtis KC. A large-scale screen for mutagen-sensitive loci in Drosophila. Genetics. 2004 May; 167(1):217-31. PMID: 15166149.
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    72. Luo P, He X, Tsang TC, Harris DT. A novel inducible amplifier expression vector for high and controlled gene expression. Int J Mol Med. 2004 Feb; 13(2):319-25. PMID: 14719141.
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    73. Zhang T, He X, Tsang TC, Harris DT. SING: a novel strategy for identifying tumor-specific, CTL-recognized tumor antigens. FASEB J. 2004 Mar; 18(3):600-2. PMID: 14734636.
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    74. He X, Tsang TC, Luo P, Zhang T, Harris DT. Enhanced tumor immunogenicity through coupling cytokine expression with antigen presentation. Cancer Gene Ther. 2003 Sep; 10(9):669-77. PMID: 12944986.
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    75. Birebent B, Mitchell E, Akis N, Li W, Somasundaram R, Purev E, Hoey D, Mastrangelo M, Maguire H, Harris DT, Nair S, Cai D, Zhang T, Herlyn DM. Monoclonal anti-idiotypic antibody mimicking the gastrointestinal carcinoma-associated epitope CO17-1A elicits antigen-specific humoral and cellular immune responses in colorectal cancer patients. Vaccine. 2003 Apr 2; 21(15):1601-12. PMID: 12639481.
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    76. Zhang T, Tsang TC, Harris DT. Efficient transduction of murine primary T cells requires a combination of high viral titer, preferred tropism, and proper timing of transduction. J Hematother Stem Cell Res. 2003 Feb; 12(1):123-30. PMID: 12662443.
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    77. Zhang T, Tsang TC, Harris DT. Comparison of cis and trans tat gene expression in HIV LTR-based amplifier vectors. Biotechniques. 2002 Nov; 33(5):1146-51. PMID: 12449396.
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    78. Harris DT, Sakiestewa D, Titone D, Young RS, Witten M. JP-8 jet fuel exposure results in immediate immunotoxicity, which is cumulative over time. Toxicol Ind Health. 2002 Mar; 18(2):77-83. PMID: 12868796.
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    79. Shibata A, Harris DT, Billings PR. Concentrations of estrogens and IGFs in umbilical cord blood plasma: a comparison among Caucasian, Hispanic, and Asian-American females. J Clin Endocrinol Metab. 2002 Feb; 87(2):810-5. PMID: 11836326.
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    80. Harris DT. Introduction: The evolution of early systemic therapy. Semin Oncol. 2001 Feb; 28(1):1-2. PMID: 11254862.
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