Alok Bhushan

TitleChair Dept Pharmaceutical Sci
InstitutionThomas Jefferson University
DepartmentJSP - Pharmaceutical Science
Address901 Walnut Street
Philadelphia PA 19107
Phone215-503-5039
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sharma N, Bhushan A, He J, Kaushal G, Bhardwaj V. Metabolic plasticity imparts erlotinib-resistance in pancreatic cancer by upregulating glucose-6-phosphate dehydrogenase. Cancer Metab. 2020; 8:19. PMID: 32974013.
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    2. Terai M, Londin E, Rochani A, Link E, Lam B, Kaushal G, Bhushan A, Orloff M, Sato T. Expression of Tryptophan 2,3-Dioxygenase in Metastatic Uveal Melanoma. Cancers (Basel). 2020 Feb 10; 12(2). PMID: 32050636.
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    3. He J, Liu W, Ge X, Wang GC, Desai V, Wang S, Mu W, Bhardwaj V, Seifert E, Liu LZ, Bhushan A, Peiper SC, Jiang BH. Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation. Toxicol Appl Pharmacol. 2019 Sep 01; 378:114606. PMID: 31170415.
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    4. Summer R, Shaghaghi H, Schriner D, Roque W, Sales D, Cuevas-Mora K, Desai V, Bhushan A, Ramirez MI, Romero F. Activation of mTORC1/PGC1 axis promotes mitochondrial biogenesis and induces cellular senescence in the lung epithelium. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20. PMID: 30892080.
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    5. Desai V, Jain A, Shaghaghi H, Summer R, Lai JCK, Bhushan A. Combination of Biochanin A and Temozolomide Impairs Tumor Growth by Modulating Cell Metabolism in Glioblastoma Multiforme. Anticancer Res. 2019 Jan; 39(1):57-66. PMID: 30591440.
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    6. Shin Y, Kokate R, Desai V, Bhushan A, Kaushal G. D-cycloserine nasal formulation development for anxiety disorders by using polymeric gels. Drug Discov Ther. 2018; 12(3):142-153. PMID: 29998995.
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    7. Desai V, Bhushan A. Natural Bioactive Compounds: Alternative Approach to the Treatment of Glioblastoma Multiforme. Biomed Res Int. 2017; 2017:9363040. PMID: 29359162.
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    8. Jain A, Lai JC, Bhushan A. Biochanin A inhibits endothelial cell functions and proangiogenic pathways: implications in glioma therapy. Anticancer Drugs. 2015 Mar; 26(3):323-30. PMID: 25501542.
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    9. Liu T, Singh R, Rios Z, Bhushan A, Li M, Sheridan PP, Bearden SE, Lai JCK, Agbenowu S, Cao S, Daniels CK. Tyrosine phosphorylation of HSC70 and its interaction with RFC mediates methotrexate resistance in murine L1210 leukemia cells. Cancer Lett. 2015 Feb 01; 357(1):231-241. PMID: 25444929.
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    10. Bhardwaj V, Tadinada SM, Jain A, Sehdev V, Daniels CK, Lai JC, Bhushan A. Biochanin A reduces pancreatic cancer survival and progression. Anticancer Drugs. 2014 Mar; 25(3):296-302. PMID: 24201306.
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    11. Liu T, Fei Z, Gangavarapu KJ, Agbenowu S, Bhushan A, Lai JC, Daniels CK, Cao S. Interleukin-6 and JAK2/STAT3 signaling mediate the reversion of dexamethasone resistance after dexamethasone withdrawal in 7TD1 multiple myeloma cells. Leuk Res. 2013 Oct; 37(10):1322-8. PMID: 23871159.
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    12. Liu T, Dean A, Ashwini S, Sheridan PP, Bhushan A, Lai JC, Cao S, Daniels CK. Identification and characterization of a 66-68-kDa protein as a methotrexate-binding protein in murine leukemia L1210 cells. Cell Stress Chaperones. 2013 Mar; 18(2):223-34. PMID: 23090015.
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    13. Lai JC, Ananthakrishnan G, Jandhyam S, Dukhande VV, Bhushan A, Gokhale M, Daniels CK, Leung SW. Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins. Int J Nanomedicine. 2010 Oct 05; 5:715-23. PMID: 21042417.
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    14. Bhardwaj V, Rizvi N, Lai MB, Lai JC, Bhushan A. Glycolytic enzyme inhibitors affect pancreatic cancer survival by modulating its signaling and energetics. Anticancer Res. 2010 Mar; 30(3):743-9. PMID: 20392992.
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    15. Puli S, Jain A, Lai JC, Bhushan A. Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. Neurochem Res. 2010 Jul; 35(7):986-93. PMID: 20177775.
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    16. Sehdev V, Lai JC, Bhushan A. Biochanin A Modulates Cell Viability, Invasion, and Growth Promoting Signaling Pathways in HER-2-Positive Breast Cancer Cells. J Oncol. 2009; 2009:121458. PMID: 20169097.
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    17. Gangavarapu KJ, Olbertz JL, Bhushan A, Lai JC, Daniels CK. Apoptotic resistance exhibited by dexamethasone-resistant murine 7TD1 cells is controlled independently of interleukin-6 triggered signaling. Apoptosis. 2008 Nov; 13(11):1394-400. PMID: 18819004.
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    18. Johnson TL, Lai MB, Lai JC, Bhushan A. Inhibition of Cell Proliferation and MAP Kinase and Akt Pathways in Oral Squamous cell Carcinoma by Genistein and Biochanin A. Evid Based Complement Alternat Med. 2010 Sep; 7(3):351-8. PMID: 18955325.
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    19. Lai JC, Lai MB, Jandhyam S, Dukhande VV, Bhushan A, Daniels CK, Leung SW. Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts. Int J Nanomedicine. 2008; 3(4):533-45. PMID: 19337421.
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    20. Puli S, Lai JC, Edgley KL, Daniels CK, Bhushan A. Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87). Neurochem Res. 2006 Oct; 31(10):1211-8. PMID: 17043766.
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    21. Puli S, Lai JC, Bhushan A. Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. J Neurooncol. 2006 Sep; 79(2):135-42. PMID: 16598420.
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    22. Rhodes RS, Kuykendall JR, Heyneman CA, May MP, Bhushan A. Stability of phenytoin sodium suspensions for the treatment of open wounds. Int J Pharm Compd. 2006 Jan-Feb; 10:74-8. PMID: 23974120.
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    23. Malthankar GV, White BK, Bhushan A, Daniels CK, Rodnick KJ, Lai JC. Differential lowering by manganese treatment of activities of glycolytic and tricarboxylic acid (TCA) cycle enzymes investigated in neuroblastoma and astrocytoma cells is associated with manganese-induced cell death. Neurochem Res. 2004 Apr; 29(4):709-17. PMID: 15098932.
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