Thomas Jefferson University

Edward Filippone

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address833 Chestnut Street
Philadelphia PA 19107
Phone215-467-8955
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rodriguez BC, Secemsky EA, Swaminathan RV, Feldman DN, Schlaich M, Battaglia Y, Filippone EJ, Krittanawong C. The Reply. Am J Med. 2024 Nov; 137(11):e221-e222. PMID: 39461803.
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    2. Filippone EJ, Gulati R, Farber JL. Contemporary review of IgA nephropathy. Front Immunol. 2024; 15:1436923. PMID: 39188719.
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    3. Ravindranath MH, Ravindranath NM, Amato-Menker CJ, Hilali FE, Filippone EJ. Conformational Alterations of the Cell Surface of Monomeric and Dimeric ?2m-Free HLA-I (Proto-HLA) May Enable Novel Immune Functions in Health and Disease. Curr Issues Mol Biol. 2024 Jul 04; 46(7):6961-6985. PMID: 39057057.
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    4. Rodriguez BC, Secemsky EA, Swaminathan RV, Feldman DN, Schlaich M, Battaglia Y, Filippone E, Krittanawong C. Opportunities and Limitations of Renal Denervation: Where Do We Stand? Am J Med. 2024 Apr 06. PMID: 38588936.
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    5. Ravindranath MH, Ravindranath NM, Amato-Menker CJ, El Hilali F, Filippone EJ. Diversity in the HLA-I Recognition of HLA-F Monoclonal Antibodies: HLA-F or HLA-Ib Monospecific, HLA-E or HLA-G Bispecific Antibodies with or without HLA-Ia Reactivity. Antibodies (Basel). 2024 Jan 31; 13(1). PMID: 38390869.
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    6. Filippone EJ, Naccarelli GV, Foy AJ. Controversies in Hypertension V: Resistant and Refractory Hypertension. Am J Med. 2023 Oct 11. PMID: 37832756.
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    7. Ravindranath MH, Ravindranath NM, Selvan SR, Hilali FE, Amato-Menker CJ, Filippone EJ. Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA? Biomolecules. 2023 07 28; 13(8). PMID: 37627243.
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    8. Filippone EJ, Naccarelli GV, Foy AJ. Controversies in Hypertension IV: Renal Denervation. Am J Med. 2023 May 23. PMID: 37230403.
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    9. Ahmed M, Nudy M, Bussa R, Filippone EJ, Foy AJ. A systematic review and meta-analysis of all sham and placebo controlled trials for resistant hypertension. Eur J Intern Med. 2023 May 05. PMID: 37150718.
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    10. Ravindranath MH, Ravindranath NM, Amato-Menker CJ, El Hilali F, Selvan SR, Filippone EJ, Morales-Buenrostro LE. Antibodies for ?2-Microglobulin and the Heavy Chains of HLA-E, HLA-F, and HLA-G Reflect the HLA-Variants on Activated Immune Cells and Phases of Disease Progression in Rheumatoid Arthritis Patients under Treatment. Antibodies (Basel). 2023 Mar 31; 12(2). PMID: 37092447.
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    11. Filippone EJ, Foy AJ, Naccarelli GV. Controversies in Hypertension III: Dipping, Nocturnal Hypertension, and the Morning Surge. Am J Med. 2023 Mar 07. PMID: 36893831.
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    12. Ahmed M, Nudy M, Bussa R, Naccarelli GV, Filippone EJ, Foy AJ. A Subgroup Meta-Analysis Comparing the Renal Denervation Sham-Controlled Randomized Trials Among Those With Resistant and Nonresistant Hypertension. Am J Cardiol. 2023 Mar 15; 191:119-124. PMID: 36669381.
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    13. Filippone EJ, Farber JL. The Histological Spectrum and Clinical Significance of T Cell-mediated Rejection of Kidney Allografts. Transplantation. 2022 Dec 19. PMID: 36584369.
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    14. Ravindranath MH, El Hilali F, Amato-Menker CJ, El Hilali H, Selvan SR, Filippone EJ. Role of HLA-I Structural Variants and the Polyreactive Antibodies They Generate in Immune Homeostasis. Antibodies (Basel). 2022 Sep 08; 11(3). PMID: 36134954.
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    15. Ahmed M, Nudy M, Bussa R, Hajduczok A, Naccarelli GV, Filippone EJ, Foy AJ. A systematic review, meta-analysis, and meta regression of the sham controlled renal denervation randomized controlled trials. Trends Cardiovasc Med. 2022 Jun 03. PMID: 35667638.
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    16. Filippone EJ, Foy AJ, Naccarelli GV. Controversies in Hypertension II: The Optimal Target Blood Pressure. Am J Med. 2022 10; 135(10):1168-1177.e3. PMID: 35636475.
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    17. Filippone EJ, Foy AJ, Naccarelli GV. Controversies in Hypertension I: The Optimal Assessment of Blood Pressure Load and Implications for Treatment. Am J Med. 2022 09; 135(9):1043-1050. PMID: 35636476.
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    18. Ravindranath MH, Ravindranath NM, El Hilali F, Selvan SR, Filippone EJ. Ramifications of the HLA-I Allelic Reactivity of Anti-HLA-E*01:01 and Anti-HLA-E*01:03 Heavy Chain Monoclonal Antibodies in Comparison with Anti-HLA-I IgG Reactivity in Non-Alloimmunized Males, Melanoma-Vaccine Recipients, and End-Stage Renal Disease Patients. Antibodies (Basel). 2022 Mar 02; 11(1). PMID: 35323192.
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    19. Ravindranath MH, Ravindranath NM, Selvan SR, Filippone EJ, Amato-Menker CJ, El Hilali F. Four Faces of Cell-Surface HLA Class-I: Their Antigenic and Immunogenic Divergence Generating Novel Targets for Vaccines. Vaccines (Basel). 2022 Feb 21; 10(2). PMID: 35214796.
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    20. Ravindranath MH, El Hilali F, Filippone EJ. The Impact of Inflammation on the Immune Responses to Transplantation: Tolerance or Rejection? Front Immunol. 2021; 12:667834. PMID: 34880853.
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    21. Filippone EJ, Newman ED, Li L, Gulati R, Farber JL. Thrombotic Microangiopathy, an Unusual Form of Monoclonal Gammopathy of Renal Significance: Report of 3 Cases and Literature Review. Front Immunol. 2021; 12:780107. PMID: 34858436.
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    22. Filippone EJ, Gulati R, Farber JL. Noninvasive Assessment of the Alloimmune Response in Kidney Transplantation. Adv Chronic Kidney Dis. 2021 11; 28(6):548-560. PMID: 35367023.
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    23. Filippone EJ, Foy AJ, Naccarelli GV. The diastolic blood pressure J-curve revisited: An update. Am Heart J Plus. 2021 Dec; 12:100065. PMID: 38559601.
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    24. Ravindranath MH, Filippone EJ, Amato-Menker CJ, Arosa FA, Das B, Ou Y, Norin AJ. Antibodies to cryptic epitopes on HLA class I and class II heavy chains bound to single antigen beads: Clinically relevant? Transpl Immunol. 2021 12; 69:101482. PMID: 34656784.
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    25. Foy AJ, Filippone EJ, Schaefer E, Nudy M, Ruzieh M, Dyer AM, Chinchilli VM, Naccarelli GV. Association Between Baseline Diastolic Blood Pressure and the Efficacy of Intensive vs Standard Blood Pressure-Lowering Therapy. JAMA Netw Open. 2021 10 01; 4(10):e2128980. PMID: 34668944.
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    26. Ravindranath MH, Hilali FE, Filippone EJ. Therapeutic Potential of HLA-I Polyreactive mAbs Mimicking the HLA-I Polyreactivity and Immunoregulatory Functions of IVIg. Vaccines (Basel). 2021 Jun 21; 9(6). PMID: 34205517.
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    27. Naccarelli GV, Filippone EJ, Foy A. Do Mineralocorticoid Receptor Antagonists Suppress Atrial?Fibrillation/Flutter? J Am Coll Cardiol. 2021 07 13; 78(2):153-155. PMID: 34015479.
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    28. Filippone EJ, Farber JL. Histologic Antibody-Mediated Kidney Allograft Rejection in the Absence of Donor Specific HLA Antibodies. Transplantation. 2021 Apr 23. PMID: 33901113.
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    29. Filippone EJ, Farber JL. The Problem of Subclinical Antibody-mediated Rejection in Kidney Transplantation. Transplantation. 2020 Nov 13. PMID: 33196628.
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    30. Filippone EJ, Farber JL. The Monitoring of Donor-Derived Cell-Free DNA (ddcfDNA) in Kidney Transplantation. Transplantation. 2020 Jul 20. PMID: 32732615.
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    31. Filippone EJ, Das B, Norin AJ, Ravindranath MH. Optimizing the assessment of pathogenic anti-HLA antibodies. Am J Transplant. 2021 01; 21(1):431-432. PMID: 32515088.
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    32. Filippone EJ, Farber JL. The Implications of B-lineage Cells in Kidney Allografts. Transplantation. 2020 Feb 07. PMID: 32039967.
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    33. Filippone EJ, Ruzieh M, Foy A. Thiazide-Associated Hyponatremia: Clinical Manifestations and Pathophysiology. Am J Kidney Dis. 2020 02; 75(2):256-264. PMID: 31606239.
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    34. Filippone EJ, Ravindranath MH. Optimizing HLA-antibody Determination. Transplantation. 2019 07; 103(7):e208. PMID: 31241557.
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    35. Ravindranath MH, Filippone EJ, Devarajan A, Asgharzadeh S. Enhancing Natural Killer and CD8+ T Cell-Mediated Anticancer Cytotoxicity and Proliferation of CD8+ T Cells with HLA-E Monospecific Monoclonal Antibodies. Monoclon Antib Immunodiagn Immunother. 2019 Apr; 38(2):38-59. PMID: 31009335.
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    36. Filippone EJ, Yadav A. Acute kidney injury after hip or knee replacement: Can we lower the risk? Cleve Clin J Med. 2019 Apr; 86(4):263-276. PMID: 30951452.
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    37. Ravindranath MH, Filippone EJ, Mahowald G, Callender C, Babu A, Saidman S, Ferrone S. Significance of the intraindividual variability of HLA IgG antibodies in renal disease patients observed with different beadsets monitored with two different secondary antibodies on a Luminex platform. Immunol Res. 2018 10; 66(5):584-604. PMID: 30324227.
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    38. Yadav A, Alijanipour P, Ackerman CT, Karanth S, Hozack WJ, Filippone EJ. Acute Kidney Injury Following Failed Total Hip and Knee Arthroplasty. J Arthroplasty. 2018 Oct; 33(10):3297-3303. PMID: 30006109.
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    39. Filippone EJ, McCue PA, Farber JL. Transplant glomerulopathy. Mod Pathol. 2018 Feb; 31(2):235-252. PMID: 29027535.
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    40. Filippone EJ, Foy AJ. Starting a Fixed-Dose Combination Pill versus a Single Agent for Patients with Hypertension. J Gen Intern Med. 2017 06; 32(6):597-598. PMID: 28275947.
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    41. Filippone EJ, Farber JL. The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies. J Immunol Res. 2016; 2016:5197396. PMID: 28070526.
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    42. Filippone EJ, Farber JL. Membranous nephropathy in the kidney allograft. Clin Transplant. 2016 Sep 20. PMID: 27646575.
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    43. Filippone EJ, Dopson SJ, Rivers DM, Monk RD, Udani SM, Jafari G, Huang SC, Melhem A, Assioun B, Schmitz PG. Adrenocorticotropic hormone analog use for podocytopathies. Int Med Case Rep J. 2016; 9:125-33. PMID: 27418857.
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    44. Filippone EJ, Farber JL. Hemophagocytic lymphohistiocytosis: an update for nephrologists. Int Urol Nephrol. 2016 Aug; 48(8):1291-304. PMID: 27098410.
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    45. Tan TL, Kheir MM, Tan DD, Filippone EJ, Tischler EH, Chen AF. Chronic Kidney Disease Linearly Predicts Outcomes After Elective Total Joint Arthroplasty. J Arthroplasty. 2016 09; 31(9 Suppl):175-179.e2. PMID: 27067757.
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    46. Cesarine J, Filippone LM, Filippone EJ. Hemophagocytic lymphohistiocytosis in the ED. Am J Emerg Med. 2016 Oct; 34(10):2057.e5-2057.e8. PMID: 27066745.
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    47. Filippone EJ, Foy AJ. Blood pressure management in the wake of SPRINT. Cleve Clin J Med. 2016 Mar; 83(3):196-8. PMID: 26974990.
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    48. Singh P, Filippone EJ, Colombe BW, Shah AP, Zhan T, Harach M, Gorn C, Frank AM. Sensitization trends after renal allograft failure: the role of DQ eplet mismatches in becoming highly sensitized. Clin Transplant. 2016 Jan; 30(1):71-80. PMID: 26529289.
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    49. Filippone EJ, Farber JL. Humoral Immune Response and Allograft Function in Kidney Transplantation. Am J Kidney Dis. 2015 Aug; 66(2):337-47. PMID: 25987262.
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    50. Filippone EJ, Farber JL. Humoral immunity in renal transplantation: epitopes, Cw and DP, and complement-activating capability - an update. Clin Transplant. 2015 Apr; 29(4):279-87. PMID: 25645090.
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    51. Filippone EJ. Idiopathic membranous nephropathy and IgG4: an interesting relationship. Clin Nephrol. 2014 Jul; 82(1):7-15. PMID: 23380389.
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    52. Filippone EJ, Gupta A, Farber JL. Normoglycemic diabetic nephropathy: the role of insulin resistance. Case Rep Nephrol Urol. 2014 May; 4(2):137-43. PMID: 25076962.
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    53. Filippone EJ, Farber JL. The specificity of acute and chronic microvascular alterations in renal allografts. Clin Transplant. 2013 Nov; 27(6):790-8. PMID: 24118527.
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    54. Foy AJ, Filippone EJ. The case for intervention bias in the practice of medicine. Yale J Biol Med. 2013 Jun; 86(2):271-80. PMID: 23766747.
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    55. Filippone EJ, Chmielewski C, Gulati R, Newman E, Farber JL. De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C. Case Rep Transplant. 2013; 2013:978481. PMID: 23844313.
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    56. Filippone EJ, Kanzaria M, Bell R, Newman E, L Farber J. Secondary membranous nephropathy associated with guillain-barr? syndrome. Case Rep Nephrol Urol. 2013 Jan; 3(1):34-9. PMID: 23626596.
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    57. Filippone EJ. Immunosuppressive treatment of idiopathic membranous nephropathy: the dilemma continues. Clin Nephrol. 2013 Feb; 79(2):143-53. PMID: 23211341.
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    58. Filippone EJ, Foy A. The J-curve revisited: a therapeutic dilemma. Cardiol Rev. 2012 Sep-Oct; 20(5):253-8. PMID: 22447043.
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    59. Foy A, Ruggiero NJ, Filippone EJ. Revascularization in renal artery stenosis. Cardiol Rev. 2012 Jul-Aug; 20(4):189-93. PMID: 22314144.
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    60. Carson JM, Newman ED, Farber JL, Filippone EJ. Tacrolimus-induced thrombotic microangiopathy: natural history of a severe, acute vasculopathy. Clin Nephrol. 2012 Jan; 77(1):79-84. PMID: 22185974.
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    61. Filippone EJ, Foy A, Galanis T, Pokuah M, Newman E, Lallas CD, Gonsalves CF, Farber JL. Segmental arterial mediolysis: report of 2 cases and review of the literature. Am J Kidney Dis. 2011 Dec; 58(6):981-7. PMID: 21872379.
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    62. Filippone EJ, Foy A, Newman E. Goal-directed antihypertensive therapy: lower may not always be better. Cleve Clin J Med. 2011 Feb; 78(2):123-33. PMID: 21285345.
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