Thomas Jefferson University

Francis Cuss

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tollman P, Panier V, Dosik D, Biondi P, Cuss F. Organizational effectiveness: a key to R&D productivity. Nat Rev Drug Discov. 2016 07; 15(7):441-2. PMID: 27312725.
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    2. Cuss F, Mullard A. Francis Cuss. Nat Rev Drug Discov. 2015 Oct; 14(10):672-3. PMID: 26361350.
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    3. Holgate ST, Bousquet J, Chung KF, Bisgaard H, Pauwels R, Fabbri L, Rabe K, Doherty M, Snell NJ, Cuss F, D'Amato M, Reginster JY. Summary of recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma. Respir Med. 2004 Jun; 98(6):479-87. PMID: 15191031.
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    4. Losco PE, Evans EW, Barat SA, Blackshear PE, Reyderman L, Fine JS, Bober LA, Anthes JC, Mirro EJ, Cuss FM. The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys. Toxicol Pathol. 2004 May-Jun; 32(3):295-308. PMID: 15204971.
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    5. Kips JC, O'Connor BJ, Langley SJ, Woodcock A, Kerstjens HA, Postma DS, Danzig M, Cuss F, Pauwels RA. Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am J Respir Crit Care Med. 2003 Jun 15; 167(12):1655-9. PMID: 12649124.
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    6. Anthes JC, Chapman RW, Richard C, Eckel S, Corboz M, Hey JA, Fernandez X, Greenfeder S, McLeod R, Sehring S, Rizzo C, Crawley Y, Shih NY, Piwinski J, Reichard G, Ting P, Carruthers N, Cuss FM, Billah M, Kreutner W, Egan RW. SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist. Eur J Pharmacol. 2002 Aug 23; 450(2):191-202. PMID: 12206858.
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    7. Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Braunschweiger K, Walsh A, Liu Z, Hayward B, Folz C, Manning SP, Bawa A, Saracino L, Thackston M, Benchekroun Y, Capparell N, Wang M, Adair R, Feng Y, Dubois J, FitzGerald MG, Huang H, Gibson R, Allen KM, Pedan A, Danzig MR, Umland SP, Egan RW, Cuss FM, Rorke S, Clough JB, Holloway JW, Holgate ST, Keith TP. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature. 2002 Jul 25; 418(6896):426-30. PMID: 12110844.
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    8. Billah MM, Cooper N, Minnicozzi M, Warneck J, Wang P, Hey JA, Kreutner W, Rizzo CA, Smith SR, Young S, Chapman RW, Dyke H, Shih NY, Piwinski JJ, Cuss FM, Montana J, Ganguly AK, Egan RW. Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor. J Pharmacol Exp Ther. 2002 Jul; 302(1):127-37. PMID: 12065709.
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    9. Billah M, Cooper N, Cuss F, Davenport RJ, Dyke HJ, Egan R, Ganguly A, Gowers L, Hannah DR, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Naylor R, Oxford J, Peake JC, Piwinski JJ, Runcie KA, Sabin V, Sharpe A, Shih NY, Warneck JB. Synthesis and profile of SCH351591, a novel PDE4 inhibitor. Bioorg Med Chem Lett. 2002 Jun 17; 12(12):1621-3. PMID: 12039576.
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    10. Ruck LM, Rizzo CA, Anthes JC, Eckel S, Egan RW, Cuss FM, Hey JA. Synergistic antiallergic activity of combined histamine H1- and cysteinyl leukotriene1-receptor blockade in human bronchus. Life Sci. 2001 May 11; 68(25):2825-34. PMID: 11432448.
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    11. Greenfeder S, Umland SP, Cuss FM, Chapman RW, Egan RW. Th2 cytokines and asthma. The role of interleukin-5 in allergic eosinophilic disease. Respir Res. 2001; 2(2):71-9. PMID: 11686868.
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    12. McLeod RL, Parra LE, Mutter JC, Erickson CH, Carey GJ, Tulshian DB, Fawzi AB, Smith-Torhan A, Egan RW, Cuss FM, Hey JA. Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors. Br J Pharmacol. 2001 Mar; 132(6):1175-8. PMID: 11250866.
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    13. Affrime MB, Cuss F, Padhi D, Wirth M, Pai S, Clement RP, Lim J, Kantesaria B, Alton K, Cayen MN. Bioavailability and metabolism of mometasone furoate following administration by metered-dose and dry-powder inhalers in healthy human volunteers. J Clin Pharmacol. 2000 Nov; 40(11):1227-36. PMID: 11075308.
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    14. Bernstein DI, Berkowitz RB, Chervinsky P, Dvorin DJ, Finn AF, Gross GN, Karetzky M, Kemp JP, Laforce C, Lumry W, Mendelson LM, Nelson H, Pearlman D, Rachelefsky G, Ratner P, Repsher L, Segal AT, Selner JC, Settipane GA, Wanderer A, Cuss FM, Nolop KB, Harrison JE. Dose-ranging study of a new steroid for asthma: mometasone furoate dry powder inhaler. Respir Med. 1999 Sep; 93(9):603-12. PMID: 10542973.
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    15. Cuss FM. Beyond the histamine receptor: effect of antihistamines on mast cells. Clin Exp Allergy. 1999 Jul; 29 Suppl 3:54-9. PMID: 10444213.
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    16. Hey JA, Affrime M, Cobert B, Kreutner W, Cuss FM. Cardiovascular profile of loratadine. Clin Exp Allergy. 1999 Jul; 29 Suppl 3:197-9. PMID: 10444237.
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    17. Cuss FM. Therapeutic effects of antibodies to interleukin-5. Allergy. 1998; 53(45 Suppl):89-92. PMID: 9788715.
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    18. Danzig M, Cuss F. Inhibition of interleukin-5 with a monoclonal antibody attenuates allergic inflammation. Allergy. 1997 Aug; 52(8):787-94. PMID: 9284977.
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    19. Nathan RA, Nolop KB, Cuss FM, Lorber RR. A comparison of double-strength beclomethasone dipropionate (84 microg) MDI with beclomethasone dipropionate (42 microg) MDI in the treatment of asthma. Chest. 1997 Jul; 112(1):34-9. PMID: 9228354.
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    20. Bronsky EA, Aaronson DW, Berkowitz RB, Chervinsky P, Graft D, Kaiser HB, Moss B, Nathan RA, Pearlman DS, Ratner PH, Adelglass JM, Southern DL, van Bavel J, Hampel F, Stricker WE, Fourr? JA, Cuss FM, Nolop KB. Dose ranging study of mometasone furoate (Nasonex) in seasonal allergic rhinitis. Ann Allergy Asthma Immunol. 1997 Jul; 79(1):51-6. PMID: 9236500.
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    21. Egan RW, Umland SP, Cuss FM, Chapman RW. Biology of interleukin-5 and its relevance to allergic disease. Allergy. 1996 Feb; 51(2):71-81. PMID: 8738511.
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    22. Hey JA, Del Prado M, Cuss FM, Egan RW, Sherwood J, Lin CC, Kreutner W. Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Clin Exp Allergy. 1995 Oct; 25(10):974-84. PMID: 8556569.
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    23. Zangrilli JG, Shaver JR, Cirelli RA, Cho SK, Garlisi CG, Falcone A, Cuss FM, Fish JE, Peters SP. sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response. Am J Respir Crit Care Med. 1995 May; 151(5):1346-53. PMID: 7537586.
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    24. Ciprandi G, Buscaglia S, Marchesi E, Danzig M, Cuss F, Canonica GW. Protective effect of loratadine on late phase reaction induced by conjunctival provocation test. Int Arch Allergy Immunol. 1993; 100(2):185-9. PMID: 8267692.
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    25. Monroe EW, Bernstein DI, Fox RW, Grabiec SV, Honsinger RW, Kalivas JT, Katz HI, Cuss F, Danzig MR, Garvin PR, et al. Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria. Arzneimittelforschung. 1992 Sep; 42(9):1119-21. PMID: 1445478.
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    26. Maxwell DL, Fuller RW, Dixon CM, Cuss FM, Barnes PJ. Ventilatory effects of substance P, vasoactive intestinal peptide, and nitroprusside in humans. J Appl Physiol (1985). 1990 Jan; 68(1):295-301. PMID: 1690202.
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    27. Chung KF, Cuss FM, Barnes PJ. Platelet activating factor: effects on bronchomotor tone and bronchial responsiveness in human beings. Allergy Proc. 1989 Sep-Oct; 10(5):333-7. PMID: 2684754.
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    28. Cuss FM. Is choice of drug delivery as important as choice of drug in childhood asthma? Agents Actions Suppl. 1988; 23:277-83. PMID: 3262994.
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    29. Cuss FM, Barnes PJ. Airway smooth muscle and disease workshop: epithelial mediators. Am Rev Respir Dis. 1987 Oct; 136(4 Pt 2):S32-5. PMID: 3310780.
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    30. Grandordy BM, Cuss FM, Barnes PJ. Breakdown of phosphoinositides in airway smooth muscle: lack of influence of anti-asthmatic drugs. Life Sci. 1987 Sep 28; 41(13):1621-7. PMID: 3041148.
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    31. Palmer JB, Cuss FM, Mulderry PK, Ghatei MA, Springall DR, Cadieux A, Bloom SR, Polak JM, Barnes PJ. Calcitonin gene-related peptide is localised to human airway nerves and potently constricts human airway smooth muscle. Br J Pharmacol. 1987 May; 91(1):95-101. PMID: 3496139.
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    32. Fuller RW, Dixon CM, Cuss FM, Barnes PJ. Bradykinin-induced bronchoconstriction in humans. Mode of action. Am Rev Respir Dis. 1987 Jan; 135(1):176-80. PMID: 3541715.
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    33. Palmer JB, Cuss FM, Barnes PJ. VIP and PHM and their role in nonadrenergic inhibitory responses in isolated human airways. J Appl Physiol (1985). 1986 Oct; 61(4):1322-8. PMID: 3781947.
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    34. Palmer JB, Cuss FM, Warren JB, Blank M, Bloom SR, Barnes PJ. Effect of infused vasoactive intestinal peptide on airway function in normal subjects. Thorax. 1986 Sep; 41(9):663-6. PMID: 3787552.
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    35. Maxwell DL, Cuss FM. Comprehensive bibliography database using a microcomputer. Br Med J (Clin Res Ed). 1986 Aug 16; 293(6544):453-4. PMID: 3091158.
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    36. Cuss FM, Dixon CM, Barnes PJ. Effects of inhaled platelet activating factor on pulmonary function and bronchial responsiveness in man. Lancet. 1986 Jul 26; 2(8500):189-92. PMID: 2873440.
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    37. Grandordy BM, Cuss FM, Sampson AS, Palmer JB, Barnes PJ. Phosphatidylinositol response to cholinergic agonists in airway smooth muscle: relationship to contraction and muscarinic receptor occupancy. J Pharmacol Exp Ther. 1986 Jul; 238(1):273-9. PMID: 3014119.
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    38. Cuss FM, Carmichael DJ, Linington A, Hulme B. Tuberculosis in renal failure: a high incidence in patients born in the Third World. Clin Nephrol. 1986 Mar; 25(3):129-33. PMID: 3955914.
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    39. Barnes P, Cuss FM. Biochemistry of airway smooth muscle. Bull Eur Physiopathol Respir. 1986; 22 Suppl 7:191-200. PMID: 3955266.
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    40. Cuss FM, Barnes PJ. The effect of inhaled nifedipine on bronchial reactivity to histamine in man. J Allergy Clin Immunol. 1985 Nov; 76(5):718-23. PMID: 4056256.
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    41. Barnes PJ, Cuss FM, Palmer JB. The effect of airway epithelium on smooth muscle contractility in bovine trachea. Br J Pharmacol. 1985 Nov; 86(3):685-91. PMID: 4063586.
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    42. Gupta S, Cuss FM, Crofton ME, Baron JH, Hodgson HJ. Budd-Chiari syndrome and alpha-1 antitrypsin deficiency. Hepatogastroenterology. 1985 Oct; 32(5):253-4. PMID: 3878321.
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    43. Cuss FM, Palmer JB, Barnes PJ. Rapid estimation of plasma theophylline concentrations. Br Med J (Clin Res Ed). 1985 Aug 10; 291(6492):384. PMID: 3926204.
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    44. Warren JB, Cuss F, Barnes PJ. Posture and theophylline kinetics. Br J Clin Pharmacol. 1985 May; 19(5):707-9. PMID: 4005108.
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    45. Cuss FM, Cola?o CB, Baron JH. Cardiac arrest after reversal of effects of opiates with naloxone. Br Med J (Clin Res Ed). 1984 Feb 04; 288(6414):363-4. PMID: 6419929.
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