Thomas Jefferson University

Yedy Israel

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address1025 Walnut St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Quintanilla ME, Israel Y. Role of Metabolism on?Alcohol Preference, Addiction, and Treatment. Curr Top Behav Neurosci. 2025; 71:193-216. PMID: 37221350.
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    2. Quintanilla ME, Santapau D, Diaz E, Valenzuela Martinez I, Medina N, Landskron G, Dominguez A, Morales P, Ram?rez D, Hermoso M, Olivares B, Berr?os-C?rcamo P, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Intragastric administration of short chain fatty acids greatly reduces voluntary ethanol intake in rats. Sci Rep. 2024 11 26; 14(1):29260. PMID: 39587197.
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    3. Quintanilla ME, Morales P, Santapau D, Gallardo J, Rebolledo R, Riveras G, Acu?a T, Herrera-Marschitz M, Israel Y, Ezquer F. Morphine self-administration is inhibited by the antioxidant N-acetylcysteine and the anti-inflammatory ibudilast; an effect enhanced by their co-administration. PLoS One. 2024; 19(10):e0312828. PMID: 39471200.
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    4. Quintanilla ME, Morales P, Santapau D, ?vila A, Ponce C, Berrios-C?rcamo P, Olivares B, Gallardo J, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Chronic Voluntary Morphine Intake Is Associated with Changes in Brain Structures Involved in Drug Dependence in a Rat Model of Polydrug Use. Int J Mol Sci. 2023 Dec 03; 24(23). PMID: 38069404.
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    5. Quezada M, Ponce C, Berr?os-C?rcamo P, Santapau D, Gallardo J, De Gregorio C, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M, Israel Y, Andr?s-Herrera P, Hip?lito L, Ezquer F. Amelioration of morphine withdrawal syndrome by systemic and intranasal administration of mesenchymal stem cell-derived secretome in preclinical models of morphine dependence. CNS Neurosci Ther. 2024 04; 30(4):e14517. PMID: 37927136.
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    6. Quintanilla ME, Quezada M, Morales P, Berr?os-C?rcamo P, Santapau D, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Effect of human mesenchymal stem cell secretome administration on morphine self-administration and relapse in two animal models of opioid dependence. Transl Psychiatry. 2022 11 04; 12(1):462. PMID: 36333316.
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    7. Ezquer F, Quintanilla ME, Morales P, Santapau D, Munita JM, Moya-Flores F, Ezquer M, Herrera-Marschitz M, Israel Y. A dual treatment blocks alcohol binge-drinking relapse: Microbiota as a new player. Drug Alcohol Depend. 2022 07 01; 236:109466. PMID: 35489181.
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    8. Berr?os-C?rcamo P, Quezada M, Santapau D, Morales P, Olivares B, Ponce C, ?vila A, De Gregorio C, Ezquer M, Quintanilla ME, Herrera-Marschitz M, Israel Y, Ezquer F. A Novel Morphine Drinking Model of Opioid Dependence in Rats. Int J Mol Sci. 2022 Mar 31; 23(7). PMID: 35409269.
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    9. Quintanilla ME, Ezquer F, Morales P, Santapau D, Ezquer M, Herrera-Marschitz M, Israel Y. A dual mechanism fully blocks ethanol relapse: Role of vagal innervation. Addict Biol. 2022 03; 27(2):e13140. PMID: 35229957.
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    10. Lespay-Rebolledo C, Tapia-Bustos A, Perez-Lobos R, Vio V, Casanova-Ortiz E, Farfan-Troncoso N, Zamorano-Cataldo M, Redel-Villarroel M, Ezquer F, Quintanilla ME, Israel Y, Morales P, Herrera-Marschitz M. Sustained Energy Deficit Following Perinatal Asphyxia: A Shift towards the Fructose-2,6-bisphosphatase (TIGAR)-Dependent Pentose Phosphate Pathway and Postnatal Development. Antioxidants (Basel). 2021 Dec 29; 11(1). PMID: 35052577.
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    11. Quintanilla ME, Morales P, Ezquer F, Ezquer M, Herrera-Marschitz M, Israel Y. Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats. Front Behav Neurosci. 2020; 14:617418. PMID: 33633548.
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    12. Ezquer F, Quintanilla ME, Moya-Flores F, Morales P, Munita JM, Olivares B, Landskron G, Hermoso MA, Ezquer M, Herrera-Marschitz M, Israel Y. Innate gut microbiota predisposes to high alcohol consumption. Addict Biol. 2021 07; 26(4):e13018. PMID: 33508889.
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    13. Farf?n N, Carril J, Redel M, Zamorano M, Araya M, Monz?n E, Alvarado R, Contreras N, Tapia-Bustos A, Quintanilla ME, Ezquer F, Vald?s JL, Israel Y, Herrera-Marschitz M, Morales P. Intranasal Administration of Mesenchymal Stem Cell Secretome Reduces Hippocampal Oxidative Stress, Neuroinflammation and Cell Death, Improving the Behavioral Outcome Following Perinatal Asphyxia. Int J Mol Sci. 2020 Oct 21; 21(20). PMID: 33096871.
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    14. Berr?os-C?rcamo P, Quezada M, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M, Israel Y, Ezquer F. Oxidative Stress and Neuroinflammation as a Pivot in Drug Abuse. A Focus on the Therapeutic Potential of Antioxidant and Anti-Inflammatory Agents and Biomolecules. Antioxidants (Basel). 2020 Sep 04; 9(9). PMID: 32899889.
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    15. Quintanilla ME, Ezquer F, Morales P, Ezquer M, Olivares B, Santapau D, Herrera-Marschitz M, Israel Y. N-Acetylcysteine and Acetylsalicylic Acid Inhibit Alcohol Consumption by Different Mechanisms: Combined Protection. Front Behav Neurosci. 2020; 14:122. PMID: 32848653.
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    16. Israel Y, Quintanilla ME, Ezquer F, Morales P, Santapau D, Berr?os-C?rcamo P, Ezquer M, Olivares B, Herrera-Marschitz M. Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation. Addict Biol. 2021 01; 26(1):e12853. PMID: 31733014.
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    17. Quintanilla ME, Ezquer F, Morales P, Santapau D, Berr?os-C?rcamo P, Ezquer M, Herrera-Marschitz M, Israel Y. Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options. Stem Cell Res Ther. 2019 07 08; 10(1):205. PMID: 31286996.
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    18. Rivera-Meza M, V?squez D, Quintanilla ME, Lagos D, Rojas B, Herrera-Marschitz M, Israel Y. Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats: A dual mechanism? Neuropharmacology. 2019 03 01; 146:175-183. PMID: 30521820.
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    19. Ezquer F, Quintanilla ME, Morales P, Santapau D, Ezquer M, Kogan MJ, Salas-Huenuleo E, Herrera-Marschitz M, Israel Y. Intranasal delivery of mesenchymal stem cell-derived exosomes reduces oxidative stress and markedly inhibits ethanol consumption and post-deprivation relapse drinking. Addict Biol. 2019 09; 24(5):994-1007. PMID: 30239077.
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    20. Quintanilla ME, Morales P, Ezquer F, Ezquer M, Herrera-Marschitz M, Israel Y. Commonality of Ethanol and Nicotine Reinforcement and Relapse in Wistar-Derived UChB Rats: Inhibition by N-Acetylcysteine. Alcohol Clin Exp Res. 2018 10; 42(10):1988-1999. PMID: 30035805.
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    21. Ezquer F, Morales P, Quintanilla ME, Santapau D, Lespay-Rebolledo C, Ezquer M, Herrera-Marschitz M, Israel Y. Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes binge-drinking. Sci Rep. 2018 03 22; 8(1):4325. PMID: 29567966.
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    22. Ezquer F, Quintanilla ME, Morales P, Ezquer M, Lespay-Rebolledo C, Herrera-Marschitz M, Israel Y. Activated mesenchymal stem cell administration inhibits chronic alcohol drinking and suppresses relapse-like drinking in high-alcohol drinker rats. Addict Biol. 2019 01; 24(1):17-27. PMID: 29044813.
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    23. Israel Y, Karahanian E, Ezquer F, Morales P, Ezquer M, Rivera-Meza M, Herrera-Marschitz M, Quintanilla ME. Acquisition, Maintenance and Relapse-Like Alcohol Drinking: Lessons from the UChB Rat Line. Front Behav Neurosci. 2017; 11:57. PMID: 28420969.
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    24. Israel Y, Ezquer F, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M. Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats. Alcohol Alcohol. 2017 Jan; 52(1):1-4. PMID: 27651282.
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    25. Quintanilla ME, Rivera-Meza M, Berr?os-C?rcamo P, Salinas-Luypaert C, Herrera-Marschitz M, Israel Y. Beyond the "First Hit": Marked Inhibition by N-Acetyl Cysteine of Chronic Ethanol Intake But Not of Early Ethanol Intake. Parallel Effects on Ethanol-Induced Saccharin Motivation. Alcohol Clin Exp Res. 2016 05; 40(5):1044-51. PMID: 27062046.
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    26. Saba LM, Flink SC, Vanderlinden LA, Israel Y, Tampier L, Colombo G, Kiianmaa K, Bell RL, Printz MP, Flodman P, Koob G, Richardson HN, Lombardo J, Hoffman PL, Tabakoff B. The sequenced rat brain transcriptome--its use in identifying networks predisposing alcohol consumption. FEBS J. 2015 Sep; 282(18):3556-78. PMID: 26183165.
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    27. Karahanian E, Rivera-Meza M, Quintanilla ME, Mu?oz D, Fern?ndez K, Israel Y. PPARa Agonists Reduce Alcohol Drinking: Do They Act in the Brain or in the Liver? Alcohol Alcohol. 2015 Nov; 50(6):717-8. PMID: 26041608.
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    28. Quintanilla ME, Rivera-Meza M, Berr?os-C?rcamo P, Cassels BK, Herrera-Marschitz M, Israel Y. (R)-Salsolinol, a product of ethanol metabolism, stereospecifically induces behavioral sensitization and leads to excessive alcohol intake. Addict Biol. 2016 11; 21(6):1063-1071. PMID: 26032572.
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    29. Israel Y, Quintanilla ME, Karahanian E, Rivera-Meza M, Herrera-Marschitz M. The "first hit" toward alcohol reinforcement: role of ethanol metabolites. Alcohol Clin Exp Res. 2015 May; 39(5):776-86. PMID: 25828063.
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    30. Karahanian E, Quintanilla ME, Fernandez K, Israel Y. Fenofibrate--a lipid-lowering drug--reduces voluntary alcohol drinking in rats. Alcohol. 2014 Nov; 48(7):665-70. PMID: 25241056.
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    31. Quintanilla ME, Rivera-Meza M, Berrios-C?rcamo PA, Bustamante D, Buscaglia M, Morales P, Karahanian E, Herrera-Marschitz M, Israel Y. Salsolinol, free of isosalsolinol, exerts ethanol-like motivational/sensitization effects leading to increases in ethanol intake. Alcohol. 2014 Sep; 48(6):551-9. PMID: 25086835.
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    32. Karahanian E, Rivera-Meza M, Tampier L, Quintanilla ME, Herrera-Marschitz M, Israel Y. Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats. Addict Biol. 2015 Mar; 20(2):336-44. PMID: 24571199.
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    33. Israel Y, Rivera-Meza M, Karahanian E, Quintanilla ME, Tampier L, Morales P, Herrera-Marschitz M. Gene specific modifications unravel ethanol and acetaldehyde actions. Front Behav Neurosci. 2013; 7:80. PMID: 23847486.
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    34. Tampier L, Quintanilla ME, Karahanian E, Rivera-Meza M, Herrera-Marschitz M, Israel Y. The alcohol deprivation effect: marked inhibition by anticatalase gene administration into the ventral tegmental area in rats. Alcohol Clin Exp Res. 2013 Aug; 37(8):1278-85. PMID: 23527889.
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    35. Juricic MA, Berr?os-C?rcamo PA, Acevedo ML, Israel Y, Almod?var I, Cassels BK. Salsolinol and isosalsolinol: condensation products of acetaldehyde and dopamine. Separation of their enantiomers in the presence of a large excess of dopamine. J Pharm Biomed Anal. 2012 Apr 07; 63:170-4. PMID: 22370127.
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    36. Encina G, Ezquer F, Conget P, Israel Y. Insulin is secreted upon glucose stimulation by both gastrointestinal enteroendocrine K-cells and L-cells engineered with the preproinsulin gene. Biol Res. 2011; 44(3):301-5. PMID: 22688918.
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    37. Quintanilla ME, Tampier L, Karahanian E, Rivera-Meza M, Herrera-Marschitz M, Israel Y. Reward and relapse: complete gene-induced dissociation in an animal model of alcohol dependence. Alcohol Clin Exp Res. 2012 Mar; 36(3):517-22. PMID: 21895710.
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    38. Karahanian E, Quintanilla ME, Tampier L, Rivera-Meza M, Bustamante D, Gonzalez-Lira V, Morales P, Herrera-Marschitz M, Israel Y. Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects. Alcohol Clin Exp Res. 2011 Apr; 35(4):606-12. PMID: 21332529.
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    39. Israel Y, Rivera-Meza M, Quintanilla ME, Sapag A, Tampier L. Acetaldehyde burst protection of ADH1B*2 against alcoholism: an additional hormesis protection against esophageal cancers following alcohol consumption? Alcohol Clin Exp Res. 2011 May; 35(5):806-10. PMID: 21284671.
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    40. Pautassi RM, Camarini R, Quadros IM, Miczek KA, Israel Y. Genetic and environmental influences on ethanol consumption: perspectives from preclinical research. Alcohol Clin Exp Res. 2010 Jun; 34(6):976-87. PMID: 20374217.
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    41. Rivera-Meza M, Quintanilla ME, Tampier L, Mura CV, Sapag A, Israel Y. Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model. FASEB J. 2010 Jan; 24(1):266-74. PMID: 19710201.
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    42. Sapag A, Gonz?lez-Mart?nez G, Lobos-Gonz?lez L, Encina G, Tampier L, Israel Y, Quintanilla ME. Polymorphisms in mitochondrial genes encoding complex I subunits are maternal factors of voluntary alcohol consumption in the rat. Pharmacogenet Genomics. 2009 Jul; 19(7):528-37. PMID: 19494790.
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    43. Cort?nez G, Sapag A, Israel Y. RNA interference against aldehyde dehydrogenase-2: development of tools for alcohol research. Alcohol. 2009 Mar; 43(2):97-104. PMID: 19251111.
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    44. Bustamante D, Quintanilla ME, Tampier L, Gonzalez-Lira V, Israel Y, Herrera-Marschitz M. Ethanol induces stronger dopamine release in nucleus accumbens (shell) of alcohol-preferring (bibulous) than in alcohol-avoiding (abstainer) rats. Eur J Pharmacol. 2008 Sep 04; 591(1-3):153-8. PMID: 18611399.
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    45. Tampier L, Quintanilla ME, Israel Y. Tolerance to disulfiram induced by chronic alcohol intake in the rat. Alcohol Clin Exp Res. 2008 Jun; 32(6):937-41. PMID: 18445101.
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    46. Ocaranza P, Quintanilla ME, Tampier L, Karahanian E, Sapag A, Israel Y. Gene therapy reduces ethanol intake in an animal model of alcohol dependence. Alcohol Clin Exp Res. 2008 Jan; 32(1):52-7. PMID: 18070247.
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    47. Quintanilla ME, Bustamante D, Tampier L, Israel Y, Herrera-Marschitz M. Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol. Eur J Pharmacol. 2007 Nov 14; 573(1-3):84-92. PMID: 17651729.
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    48. Quintanilla ME, Tampier L, Sapag A, Gerdtzen Z, Israel Y. Sex differences, alcohol dehydrogenase, acetaldehyde burst, and aversion to ethanol in the rat: a systems perspective. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E531-7. PMID: 17488809.
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    49. Quintanilla ME, Israel Y, Sapag A, Tampier L. The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake. Addict Biol. 2006 Sep; 11(3-4):310-23. PMID: 16961761.
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    50. Kandov Y, Israel Y, Kest A, Dostova I, Verasammy J, Bernal SY, Kasselman L, Bodnar RJ. GABA receptor subtype antagonists in the nucleus accumbens shell and ventral tegmental area differentially alter feeding responses induced by deprivation, glucoprivation and lipoprivation in rats. Brain Res. 2006 Apr 12; 1082(1):86-97. PMID: 16516868.
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    51. Ezquer F, N??ez MT, Rojas A, Asenjo J, Israel Y. Hereditary hemochromatosis: an opportunity for gene therapy. Biol Res. 2006; 39(1):113-24. PMID: 16629172.
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    52. Israel Y, Quintanilla ME, Sapag A, Tampier L. Combined effects of aldehyde dehydrogenase variants and maternal mitochondrial genes on alcohol consumption. Alcohol Res Health. 2006; 29(4):281-5. PMID: 17718407.
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    53. Karahanian E, Ocaranza P, Israel Y. Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA. Alcohol Clin Exp Res. 2005 Aug; 29(8):1384-9. PMID: 16131845.
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    54. Luo HR, Israel Y, Tu GC, Eriksson CJ, Zhang YP. Genetic polymorphism of aldehyde dehydrogenase 2 (ALDH2) in a Chinese population: gender, age, culture, and genotypes of ALDH2. Biochem Genet. 2005 Jun; 43(5-6):223-7. PMID: 16144299.
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    55. Quintanilla ME, Tampier L, Sapag A, Israel Y. Polymorphisms in the mitochondrial aldehyde dehydrogenase gene (Aldh2) determine peak blood acetaldehyde levels and voluntary ethanol consumption in rats. Pharmacogenet Genomics. 2005 Jun; 15(6):427-31. PMID: 15900217.
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    56. Ezquer F, N??ez MT, Israel Y. Antisense gene delivered by an adenoassociated viral vector inhibits iron uptake in human intestinal cells: potential application in hemochromatosis. Biochem Pharmacol. 2005 Jun 01; 69(11):1559-66. PMID: 15896335.
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    57. Israel Y, Kandov Y, Khaimova E, Kest A, Lewis SR, Pasternak GW, Pan YX, Rossi GC, Bodnar RJ. NPY-induced feeding: pharmacological characterization using selective opioid antagonists and antisense probes in rats. Peptides. 2005 Jul; 26(7):1167-75. PMID: 15949635.
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    58. Quintanilla ME, Tampier L, Valle-Prieto A, Sapag A, Israel Y. Complex I regulates mutant mitochondrial aldehyde dehydrogenase activity and voluntary ethanol consumption in rats. FASEB J. 2005 Jan; 19(1):36-42. PMID: 15629893.
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    59. Ponnappa BC, Israel Y, Aini M, Zhou F, Russ R, Cao QN, Hu Y, Rubin R. Inhibition of tumor necrosis factor alpha secretion and prevention of liver injury in ethanol-fed rats by antisense oligonucleotides. Biochem Pharmacol. 2005 Feb 15; 69(4):569-77. PMID: 15670576.
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    60. Hadjimarkou MM, Singh A, Kandov Y, Israel Y, Pan YX, Rossi GC, Pasternak GW, Bodnar RJ. Opioid receptor involvement in food deprivation-induced feeding: evaluation of selective antagonist and antisense oligodeoxynucleotide probe effects in mice and rats. J Pharmacol Exp Ther. 2004 Dec; 311(3):1188-202. PMID: 15333676.
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    61. Rodriguez DA, Moncada C, N??ez MT, Lavandero S, Ponnappa BC, Israel Y. Ethanol increases tumor necrosis factor-alpha receptor-1 (TNF-R1) levels in hepatic, intestinal, and cardiac cells. Alcohol. 2004 May; 33(1):9-15. PMID: 15353169.
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    62. Videla LA, Tapia G, Varela P, Cornejo P, Guerrero J, Israel Y, Fern?ndez V. Effects of acute gamma-hexachlorocyclohexane intoxication in relation to the redox regulation of nuclear factor-kappaB, cytokine gene expression, and liver injury in the rat. Antioxid Redox Signal. 2004 Apr; 6(2):471-80. PMID: 15025948.
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    63. Anni H, Pristatsky P, Israel Y. Binding of acetaldehyde to a glutathione metabolite: mass spectrometric characterization of an acetaldehyde-cysteinylglycine conjugate. Alcohol Clin Exp Res. 2003 Oct; 27(10):1613-21. PMID: 14574232.
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    64. Moncada C, Fuentes N, Lladser A, Encina G, Sapag A, Karahanian E, Israel Y. Use of an "acetaldehyde clamp" in the determination of low-KM aldehyde dehydrogenase activity in H4-II-E-C3 rat hepatoma cells. Alcohol. 2003 Aug-Oct; 31(1-2):19-24. PMID: 14615007.
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    65. Sapag A, Tampier L, Valle-Prieto A, Quintanilla ME, Moncada C, Israel Y. Mutations in mitochondrial aldehyde dehydrogenase (ALDH2) change cofactor affinity and segregate with voluntary alcohol consumption in rats. Pharmacogenetics. 2003 Aug; 13(8):509-15. PMID: 12893989.
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    66. Fernandez V, Videla LA, Tapia G, Israel Y. Increases in tumor necrosis factor-alpha in response to thyroid hormone-induced liver oxidative stress in the rat. Free Radic Res. 2002 Jul; 36(7):719-25. PMID: 12180121.
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    67. Ponnappa BC, Israel Y. Targeting Kupffer cells with antisense oligonucleotides. Front Biosci. 2002 May 01; 7:e223-33. PMID: 11991849.
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    68. Israel Y, Lieber CS. The Research Society on Alcoholism. Addiction. 2002 May; 97(5):483-6. PMID: 12033649.
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    69. Israel Y, Crews FT, Thurman RG, Tu GC, Garver E, Ponnappa B, Karahanian E, Rubin R, Hoplight B, Sethna M, Hanes R, Wilkie MB, Wheeler MD. Gene and antisense delivery in alcoholism research. Alcohol Clin Exp Res. 2002 Apr; 26(4):582-5. PMID: 11981136.
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    70. Anni H, Israel Y. Proteomics in alcohol research. Alcohol Res Health. 2002; 26(3):219-32. PMID: 12875051.
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    71. Moncada C, Israel Y. Protein binding of alpha-hydroxyethyl free radicals. Alcohol Clin Exp Res. 2001 Dec; 25(12):1723-8. PMID: 11781504.
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    72. L? AD, Israel Y, Juzytsch W, Quan B, Harding S. Genetic selection for high and low alcohol consumption in a limited-access paradigm. Alcohol Clin Exp Res. 2001 Nov; 25(11):1613-20. PMID: 11707636.
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    73. Anni H, Nikolaeva O, Israel Y. Selection of phage-display library peptides recognizing ethanol targets on proteins. Alcohol. 2001 Nov; 25(3):201-9. PMID: 11839467.
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    74. Garver E, Cao QN, Aini M, Zhou F, Israel Y. Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol. J Exp Med. 2001 Sep 03; 194(5):571-80. PMID: 11535626.
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    75. Ponnappa BC, Dey I, Tu GC, Zhou F, Aini M, Cao QN, Israel Y. In vivo delivery of antisense oligonucleotides in pH-sensitive liposomes inhibits lipopolysaccharide-induced production of tumor necrosis factor-alpha in rats. J Pharmacol Exp Ther. 2001 Jun; 297(3):1129-36. PMID: 11356938.
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    76. Lakshman R, Tsutsumi M, Ghosh P, Takase S, Anni H, Nikolaeva O, Israel Y, Anton RF, Lesch OM, Helender A, Eriksson G, Jeppson JO, Marmillot P, Rao MN. Alcohol biomarkers: clinical significance and biochemical basis. Alcohol Clin Exp Res. 2001 May; 25(5 Suppl ISBRA):67S-70S. PMID: 11391052.
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    77. Garver E, Ross AD, Tu GC, Cao QN, Zhou F, Israel Y. Paradigm to test a drug-induced aversion to ethanol. Alcohol Alcohol. 2000 Sep-Oct; 35(5):435-8. PMID: 11022016.
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    78. Viitala K, Makkonen K, Israel Y, Lehtim?ki T, Jaakkola O, Koivula T, Blake JE, Niemel? O. Autoimmune responses against oxidant stress and acetaldehyde-derived epitopes in human alcohol consumers. Alcohol Clin Exp Res. 2000 Jul; 24(7):1103-9. PMID: 10924016.
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    79. Spandorfer JM, Israel Y, Turner BJ. Primary care physicians' views on screening and management of alcohol abuse: inconsistencies with national guidelines. J Fam Pract. 1999 Nov; 48(11):899-902. PMID: 10907628.
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    80. Moncada C, Israel Y. Generation of acetate and production of ethyl-lysine in the reaction of acetaldehyde plus serum albumin. Alcohol. 1999 Jan; 17(1):87-91. PMID: 9895041.
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    81. Anni H, Israel Y. Characterization of adducts of ethanol metabolites with cytochrome c. Alcohol Clin Exp Res. 1999 Jan; 23(1):26-37. PMID: 10029200.
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    82. Tu GC, Cao QN, Zhou F, Israel Y. Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design. J Biol Chem. 1998 Sep 25; 273(39):25125-31. PMID: 9737971.
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    83. Ross AD, Dey I, Janes N, Israel Y. Effect of antithyroid drugs on hydroxyl radical formation and alpha-1-proteinase inhibitor inactivation by neutrophils: therapeutic implications. J Pharmacol Exp Ther. 1998 Jun; 285(3):1233-8. PMID: 9618427.
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    84. Ross AD, Saldivia V, Oporto B, Carmichael FJ, Cameron R, Israel Y. Circulating neutrophils and liver injury in rat models of experimental alcoholic liver disease. Alcohol Clin Exp Res. 1998 Feb; 22(1):197-201. PMID: 9514307.
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    85. Israel Y. Antibodies against ethanol-derived protein adducts: pathogenic implications. Gastroenterology. 1997 Jul; 113(1):353-5. PMID: 9207300.
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    86. Viitala K, Israel Y, Blake JE, Niemel? O. Serum IgA, IgG, and IgM antibodies directed against acetaldehyde-derived epitopes: relationship to liver disease severity and alcohol consumption. Hepatology. 1997 Jun; 25(6):1418-24. PMID: 9185762.
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    87. Israel Y, Hollander O, Sanchez-Craig M, Booker S, Miller V, Gingrich R, Rankin JG. Screening for problem drinking and counseling by the primary care physician-nurse team. Alcohol Clin Exp Res. 1996 Nov; 20(8):1443-50. PMID: 8947323.
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    88. Clot P, Albano E, Eliasson E, Tabone M, Aric? S, Israel Y, Moncada C, Ingelman-Sundberg M. Cytochrome P4502E1 hydroxyethyl radical adducts as the major antigen in autoantibody formation among alcoholics. Gastroenterology. 1996 Jul; 111(1):206-16. PMID: 8698201.
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    89. Sorvaj?rvi K, Blake JE, Israel Y, Niemel? O. Sensitivity and specificity of carbohydrate-deficient transferrin as a marker of alcohol abuse are significantly influenced by alterations in serum transferrin: comparison of two methods. Alcohol Clin Exp Res. 1996 May; 20(3):449-54. PMID: 8727236.
      Citations:    
    90. Tu GC, Cao QN, Israel Y. Inhibition of gene expression by triple helix formation in hepatoma cells. J Biol Chem. 1995 Nov 24; 270(47):28402-7. PMID: 7499344.
      Citations:    
    91. Niemel? O, Sorvaj?rvi K, Blake JE, Israel Y. Carbohydrate-deficient transferrin as a marker of alcohol abuse: relationship to alcohol consumption, severity of liver disease, and fibrogenesis. Alcohol Clin Exp Res. 1995 Oct; 19(5):1203-8. PMID: 8561291.
      Citations:    
    92. Ross AD, Varghese G, Oporto B, Carmichael FJ, Israel Y. Effect of propylthiouracil treatment on NADPH-cytochrome P450 reductase levels, oxygen consumption and hydroxyl radical formation in liver microsomes from rats fed ethanol or acetone chronically. Biochem Pharmacol. 1995 Mar 30; 49(7):979-89. PMID: 7741770.
      Citations:    
    93. Tu GC, Israel Y. Alcohol consumption by orientals in North America is predicted largely by a single gene. Behav Genet. 1995 Jan; 25(1):59-65. PMID: 7755519.
      Citations:    
    94. Moncada C, Torres V, Varghese G, Albano E, Israel Y. Ethanol-derived immunoreactive species formed by free radical mechanisms. Mol Pharmacol. 1994 Oct; 46(4):786-91. PMID: 7969061.
      Citations:    
    95. L? AD, Israel Y. A simple technique for quantifying intoxication-induced by low doses of ethanol. Pharmacol Biochem Behav. 1994 May; 48(1):229-34. PMID: 8029294.
      Citations:    
    96. Niemel? O, Parkkila S, Yl?-Herttuala S, Halsted C, Witztum JL, Lanca A, Israel Y. Covalent protein adducts in the liver as a result of ethanol metabolism and lipid peroxidation. Lab Invest. 1994 Apr; 70(4):537-46. PMID: 8176892.
      Citations:    
    97. Israel Y, Orrego H, Carmichael FJ. Acetate-mediated effects of ethanol. Alcohol Clin Exp Res. 1994 Feb; 18(1):144-8. PMID: 8198211.
      Citations:    
    98. Lan?a AJ, Grupp LA, Israel Y. Reduction of voluntary alcohol consumption in the rat by transplantation of hypothalamic grafts. Brain Res. 1993 Dec 31; 632(1-2):287-95. PMID: 8149234.
      Citations:    
    99. George SR, Cheng R, Nguyen T, Israel Y, O'Dowd BF. Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism. Biochem Biophys Res Commun. 1993 Oct 15; 196(1):107-14. PMID: 8216280.
      Citations:    
    100. Tu GC, Israel Y. A new approach for the rapid detection of common and atypical aldehyde dehydrogenase alleles. Eur J Clin Chem Clin Biochem. 1993 Sep; 31(9):591-4. PMID: 8260531.
      Citations:    
    101. Carmichael FJ, Orrego H, Saldivia V, Israel Y. Effect of propylthiouracil on the ethanol-induced increase in liver oxygen consumption in awake rats. Hepatology. 1993 Aug; 18(2):415-21. PMID: 8340071.
      Citations:    
    102. Moncada C, Torres V, Israel Y. Simple method for the preparation of antigen emulsions for immunization. J Immunol Methods. 1993 Jun 04; 162(1):133-40. PMID: 8509648.
      Citations:    
    103. Carmichael FJ, Orrego H, Israel Y. Acetate-induced adenosine mediated effects of ethanol. Alcohol Alcohol Suppl. 1993; 2:411-8. PMID: 7748331.
      Citations:    
    104. Lu Y, O'Dowd BF, Orrego H, Israel Y. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase. Biochem Biophys Res Commun. 1992 Dec 15; 189(2):749-58. PMID: 1339280.
      Citations:    
    105. Israel Y, MacDonald A, Niemel? O, Zamel D, Shami E, Zywulko M, Klajner F, Borgono C. Hypersensitivity to acetaldehyde-protein adducts. Mol Pharmacol. 1992 Oct; 42(4):711-7. PMID: 1435747.
      Citations:    
    106. Niemel? O, Israel Y. Hemoglobin-acetaldehyde adducts in human alcohol abusers. Lab Invest. 1992 Aug; 67(2):246-52. PMID: 1380106.
      Citations:    
    107. Sillanaukee P, Seppa K, Koivula T, Israel Y, Niemela O. Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods. J Lab Clin Med. 1992 Jul; 120(1):42-7. PMID: 1613327.
      Citations:    
    108. Tu GC, Kapur B, Israel Y. Characteristics of a new urine, serum, and saliva alcohol reagent strip. Alcohol Clin Exp Res. 1992 Apr; 16(2):222-7. PMID: 1590543.
      Citations:    
    109. Lan?a AJ, Israel Y. Histochemical demonstration of sinusoidal gamma-glutamyltransferase activity by substrate protection fixation: comparative studies in rat and guinea pig liver. Hepatology. 1991 Nov; 14(5):857-63. PMID: 1718834.
      Citations:    
    110. Carmichael FJ, Israel Y, Crawford M, Minhas K, Saldivia V, Sandrin S, Campisi P, Orrego H. Central nervous system effects of acetate: contribution to the central effects of ethanol. J Pharmacol Exp Ther. 1991 Oct; 259(1):403-8. PMID: 1920128.
      Citations:    
    111. Israel Y, Orrego H, Schmidt W, Popham RE, Escartin P, Ishii H, Kelly D, Long JP, Malizia G, Mezey E, et al. Trauma in cirrhosis: an indicator of the pattern of alcohol abuse in different societies. Alcohol Clin Exp Res. 1991 Jun; 15(3):433-7. PMID: 1877730.
      Citations:    
    112. Niemel? O, Israel Y, Mizoi Y, Fukunaga T, Eriksson CJ. Hemoglobin-acetaldehyde adducts in human volunteers following acute ethanol ingestion. Alcohol Clin Exp Res. 1990 Dec; 14(6):838-41. PMID: 2088118.
      Citations:    
    113. Sunahara RK, Niznik HB, Weiner DM, Stormann TM, Brann MR, Kennedy JL, Gelernter JE, Rozmahel R, Yang YL, Israel Y, et al. Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature. 1990 Sep 06; 347(6288):80-3. PMID: 1975640.
      Citations:    
    114. O'Dowd BF, Rothhammer F, Israel Y. Genotyping of mitochondrial aldehyde dehydrogenase locus of Native American Indians. Alcohol Clin Exp Res. 1990 Aug; 14(4):531-3. PMID: 2221278.
      Citations:    
    115. Speisky H, Israel Y. Gamma-glutamyl transferase ectoactivity in the intact rat liver: effect of chronic alcohol consumption. Alcohol. 1990 Jul-Aug; 7(4):339-47. PMID: 1975183.
      Citations:    
    116. Speisky H, Shackel N, Varghese G, Wade D, Israel Y. Role of hepatic gamma-glutamyltransferase in the degradation of circulating glutathione: studies in the intact guinea pig perfused liver. Hepatology. 1990 May; 11(5):843-9. PMID: 1971805.
      Citations:    
    117. O'Dowd BF, Nguyen T, Tirpak A, Jarvie KR, Israel Y, Seeman P, Niznik HB. Cloning of two additional catecholamine receptors from rat brain. FEBS Lett. 1990 Mar 12; 262(1):8-12. PMID: 2138567.
      Citations:    
    118. Kawasaki T, Carmichael FJ, Giles G, Saldivia V, Israel Y, Orrego H. Effects of propylthiouracil and methimazole on splanchnic hemodynamics in awake and unrestrained rats. Hepatology. 1989 Sep; 10(3):273-8. PMID: 2759545.
      Citations:    
    119. Israel Y. Covalent binding of acetaldehyde to liver tubulin: a step in the right direction. Hepatology. 1989 Jan; 9(1):161-2. PMID: 2642293.
      Citations:    
    120. Carmichael FJ, Saldivia V, Varghese GA, Israel Y, Orrego H. Ethanol-induced increase in portal blood flow: role of acetate and A1- and A2-adenosine receptors. Am J Physiol. 1988 Oct; 255(4 Pt 1):G417-23. PMID: 3177642.
      Citations:    
    121. Israel Y, MacDonald A, Waks T, Niemel? O. Induction of an allergic reaction to alcohol metabolites by immunization. Arch Biol Med Exp. 1988 Jun; 21(1):71-3. PMID: 3154868.
      Citations:    
    122. Orrego H, Carmichael FJ, Saldivia V, Giles HG, Sandrin S, Israel Y. Ethanol-induced increase in portal blood flow: role of adenosine. Am J Physiol. 1988 Apr; 254(4 Pt 1):G495-501. PMID: 3354671.
      Citations:    
    123. Speisky H, Kera Y, Penttil? KE, Israel Y, Lindros KO. Depletion of hepatic glutathione by ethanol occurs independently of ethanol metabolism. Alcohol Clin Exp Res. 1988 Apr; 12(2):224-8. PMID: 3287984.
      Citations:    
    124. Giles HG, Sandrin S, Saldivia V, Israel Y. Noninvasive estimation of blood alcohol concentrations: ethanol vapor above the eye. Alcohol Clin Exp Res. 1988 Apr; 12(2):255-8. PMID: 3287989.
      Citations:    
    125. Teichert-Kuliszewska K, Israel Y, Cinader B. Alcohol dehydrogenase is not a major determinant of alcohol preference in mice. Alcohol. 1988 Jan-Feb; 5(1):45-7. PMID: 3355668.
      Citations:    
    126. Orrego H, Carmichael FJ, Israel Y. New insights on the mechanism of the alcohol-induced increase in portal blood flow. Can J Physiol Pharmacol. 1988 Jan; 66(1):1-9. PMID: 3285979.
      Citations:    
    127. Carmichael FJ, Israel Y, Saldivia V, Giles HG, Meggiorini S, Orrego H. Blood acetaldehyde and the ethanol-induced increase in splanchnic circulation. Biochem Pharmacol. 1987 Aug 15; 36(16):2673-8. PMID: 3606666.
      Citations:    
    128. Schmidt W, Popham RE, Israel Y. Dose-specific effects of alcohol on the lifespan of mice and the possible relevance to man. Br J Addict. 1987 Jul; 82(7):775-88. PMID: 3478068.
      Citations:    
    129. Giles HG, Meggiorini S, Renaud GE, Thiessen JJ, Vidins EI, Compton KV, Saldivia V, Orrego H, Israel Y. Ethanol vapor above skin: determination by a gas sensor instrument and relationship with plasma concentration. Alcohol Clin Exp Res. 1987 Jun; 11(3):249-53. PMID: 3307488.
      Citations:    
    130. Orrego H, Israel Y. Alcohol-induced hepatocyte enlargement: transfer of susceptibility to offspring. Alcohol Clin Exp Res. 1987 Jun; 11(3):321-2. PMID: 3307501.
      Citations:    
    131. Carmichael FJ, Saldivia V, Israel Y, McKaigney JP, Orrego H. Ethanol-induced increase in portal hepatic blood flow: interference by anesthetic agents. Hepatology. 1987 Jan-Feb; 7(1):89-94. PMID: 3804210.
      Citations:    
    132. Speisky H, Gunasekara A, Varghese G, Israel Y. Basolateral gamma-glutamyl transferase ectoactivity in rat liver: effects of chronic alcohol consumption. Alcohol Alcohol Suppl. 1987; 1:245-9. PMID: 2892497.
      Citations:    
    133. Tang BK, Devenyi P, Teller D, Israel Y. Detection of an alcohol specific product in urine of alcoholics. Biochem Biophys Res Commun. 1986 Nov 14; 140(3):924-7. PMID: 3778493.
      Citations:    
    134. Israel Y, Hurwitz E, Niemel? O, Arnon R. Monoclonal and polyclonal antibodies against acetaldehyde-containing epitopes in acetaldehyde-protein adducts. Proc Natl Acad Sci U S A. 1986 Oct; 83(20):7923-7. PMID: 2429322.
      Citations:    
    135. Giles HG, Renaud GE, Meggiorini S, Israel Y. New instrument using gas sensors for the quantitative analysis of ethanol in biological liquids. Alcohol Clin Exp Res. 1986 Oct; 10(5):521-5. PMID: 3541677.
      Citations:    
    136. Skinner HA, Holt S, Sheu WJ, Israel Y. Clinical versus laboratory detection of alcohol abuse: the alcohol clinical index. Br Med J (Clin Res Ed). 1986 Jun 28; 292(6537):1703-8. PMID: 3089362.
      Citations:    
    137. McKaigney JP, Carmichael FJ, Saldivia V, Israel Y, Orrego H. Role of ethanol metabolism in the ethanol-induced increase in splanchnic circulation. Am J Physiol. 1986 Apr; 250(4 Pt 1):G518-23. PMID: 3963196.
      Citations:    
    138. Rachamin G, Israel Y. Sex differences in hepatic alcohol dehydrogenase activity in animal species. Biochem Pharmacol. 1985 Jul 01; 34(13):2385-6. PMID: 3160354.
      Citations:    
    139. Rachamin G, Okuno F, Israel Y. Inhibitory effect of propylthiouracil on the development of metabolic tolerance to ethanol. Biochem Pharmacol. 1985 Jul 01; 34(13):2377-83. PMID: 3160353.
      Citations:    
    140. Vidins EI, Britton RS, Medline A, Blendis LM, Israel Y, Orrego H. Sinusoidal caliber in alcoholic and nonalcoholic liver disease: diagnostic and pathogenic implications. Hepatology. 1985 May-Jun; 5(3):408-14. PMID: 3997070.
      Citations:    
    141. Speisky H, Bunout D, Orrego H, Giles HG, Gunasekara A, Israel Y. Lack of changes in diene conjugate levels following ethanol induced glutathione depletion or hepatic necrosis. Res Commun Chem Pathol Pharmacol. 1985 Apr; 48(1):77-90. PMID: 3992031.
      Citations:    
    142. Sanchez-Craig M, Israel Y. Pattern of alcohol use associated with self-identified problem drinking. Am J Public Health. 1985 Feb; 75(2):178-80. PMID: 3966626.
      Citations:    
    143. Speisky H, MacDonald A, Giles G, Orrego H, Israel Y. Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies. Biochem J. 1985 Feb 01; 225(3):565-72. PMID: 3977847.
      Citations:    
    144. Orrego H, Blake JE, Israel Y. Relationship between gamma-glutamyl transpeptidase and mean urinary alcohol levels in alcoholics while drinking and after alcohol withdrawal. Alcohol Clin Exp Res. 1985 Jan-Feb; 9(1):10-3. PMID: 2859812.
      Citations:    
    145. Israel Y, Tang BK, Tedesco JL, Macdonald J, Macdonald A. Alcohol abuse: detection of acetaldehyde adducts in rat urine following administration of erythrocytes labelled with radioactive acetaldehyde. Prog Clin Biol Res. 1985; 183:31-7. PMID: 3901022.
      Citations:    
    146. Skinner HA, Holt S, Schuller R, Roy J, Israel Y. Identification of alcohol abuse using laboratory tests and a history of trauma. Ann Intern Med. 1984 Dec; 101(6):847-51. PMID: 6149716.
      Citations:    
    147. Britton RS, Videla LA, Rachamin G, Okuno F, Israel Y. Effect of age on metabolic tolerance and hepatomegaly following chronic ethanol administration. Alcohol Clin Exp Res. 1984 Nov-Dec; 8(6):528-34. PMID: 6393802.
      Citations:    
    148. Israel Y, Oporto B, Macdonald AD. Simultaneous pair-feeding system for the administration of alcohol-containing liquid diets. Alcohol Clin Exp Res. 1984 Sep-Oct; 8(5):505-8. PMID: 6391266.
      Citations:    
    149. Rachamin G, Britton RS, Macdonald JA, Israel Y. The inhibitory effect of testosterone on the development of metabolic tolerance to ethanol. Alcohol. 1984 Jul-Aug; 1(4):283-91. PMID: 6399210.
      Citations:    
    150. Israel Y, Orrego H. Hypermetabolic state and hypoxic liver damage. Recent Dev Alcohol. 1984; 2:119-33. PMID: 6328588.
      Citations:    
    151. Orrego H, Israel Y, Blake JE, Medline A. Assessment of prognostic factors in alcoholic liver disease: toward a global quantitative expression of severity. Hepatology. 1983 Nov-Dec; 3(6):896-905. PMID: 6629318.
      Citations:    
    152. Colman JC, Britton RS, Orrego H, Saldivia V, Medline A, Israel Y. Relation between osmotically induced hepatocyte enlargement and portal hypertension. Am J Physiol. 1983 Sep; 245(3):G382-7. PMID: 6614181.
      Citations:    
    153. Okuno F, Orrego H, Israel Y. Calcium requirement for anoxic liver cell injury. Res Commun Chem Pathol Pharmacol. 1983 Mar; 39(3):437-44. PMID: 6856948.
      Citations:    
    154. Israel Y, Orrego H. On the characteristics of alcohol-induced liver enlargement and its possible hemodynamic consequences. Pharmacol Biochem Behav. 1983; 18 Suppl 1:433-7. PMID: 6634854.
      Citations:    
    155. Khanna JM, Israel Y, Kalant H, Mayer JM. Metabolic tolerance as related to initial rates of ethanol metabolism. Biochem Pharmacol. 1982 Oct 01; 31(19):3140-1. PMID: 7150341.
      Citations:    
    156. Yuki T, Israel Y, Thurman RG. The swift increase in alcohol metabolism. Inhibition by propylthiouracil. Biochem Pharmacol. 1982 Jul 15; 31(14):2403-7. PMID: 7126252.
      Citations:    
    157. Israel Y, Orrego H, Colman JC, Britton RS. Alcohol-induced hepatomegaly: pathogenesis and role in the production of portal hypertension. Fed Proc. 1982 Jun; 41(8):2472-7. PMID: 7084488.
      Citations:    
    158. Robinson GM, Orrego H, Israel Y, Devenyi P, Kapur BM. Low-molecular-weight polyethylene glycol as a probe of gastrointestinal permeability after alcohol ingestion. Dig Dis Sci. 1981 Nov; 26(11):971-7. PMID: 7297377.
      Citations:    
    159. Orrego H, Israel Y, Crossley IR, Mahmoud AA, Peters PA, Varghese G, Wanless IR. Effect of chronic alcohol intake on hepatic fibrosis and granulomas in murine schistosomiasis mansoni. Hepatology. 1981 Sep-Oct; 1(5):416-8. PMID: 7308986.
      Citations:    
    160. Wahid S, Khanna JM, Carmichael FJ, Lindros KO, Rachamin G, Israel Y. Alcohol-induced redox changes in the liver of the spontaneously hypertensive rat: effect of chronic ethanol treatment. Biochem Pharmacol. 1981 Jun 01; 30(11):1277-82. PMID: 7023484.
      Citations:    
    161. Holt S, Skinner HA, Israel Y. Early identification of alcohol abuse: 2: Clinical and laboratory indicators. Can Med Assoc J. 1981 May 15; 124(10):1279-94, 1299. PMID: 7016289.
      Citations:    
    162. Orrego H, Israel Y, Blendis LM. Alcoholic liver disease: information in search of knowledge? Hepatology. 1981 May-Jun; 1(3):267-83. PMID: 6169616.
      Citations:    
    163. Orrego H, Blendis LM, Crossley IR, Medline A, Macdonald A, Ritchie S, Israel Y. Correlation of intrahepatic pressure with collagen in the Disse space and hepatomegaly in humans and in the rat. Gastroenterology. 1981 Mar; 80(3):546-56. PMID: 7450445.
      Citations:    
    164. Orrego H, Crossley IR, Saldivia V, Medline A, Varghese G, Israel Y. Long-term ethanol administration and short- and long-term liver regeneration after partial hepatectomy. J Lab Clin Med. 1981 Feb; 97(2):221-30. PMID: 7452093.
      Citations:    
    165. Iturriaga H, Bunout D, Petermann M, Ugarte G, Israel Y. Effects of ethanol on hepatic blood flow in the rat. Alcohol Clin Exp Res. 1981; 5(2):221-4. PMID: 7018301.
      Citations:    
    166. Wahid S, Khanna JM, Carmichael FJ, Israel Y. Mitochondrial function following chronic ethanol treatment: effect of diet. Res Commun Chem Pathol Pharmacol. 1980 Dec; 30(3):477-91. PMID: 7196064.
      Citations:    
    167. Britton RS, Israel Y. Effect of 6-n-propyl-2-thiouracil on the rate of ethanol metabolism in rats treated chronically with ethanol. Biochem Pharmacol. 1980 Nov 01; 29(21):2951-5. PMID: 7192984.
      Citations:    
    168. Israel Y, Orrego H, Holt S, Macdonald DW, Meema HE. Identification of alcohol abuse: thoracic fractures on routine chest X-rays as indicators of alcoholism. Alcohol Clin Exp Res. 1980 Oct; 4(4):420-2. PMID: 7004243.
      Citations:    
    169. Iturriaga H, Ugarte G, Israel Y. Hepatic vein oxygenation, liver blood flow, and the rate of ethanol metabolism in recently abstinent alcoholic patients. Eur J Clin Invest. 1980 Jun; 10(3):211-8. PMID: 6783417.
      Citations:    
    170. Rachamin G, MacDonald JA, Wahid S, Clapp JJ, Khanna JM, Israel Y. Modulation of alcohol dehydrogenase and ethanol metabolism by sex hormones in the spontaneously hypertensive rat. Effect of chronic ethanol administration. Biochem J. 1980 Feb 15; 186(2):483-90. PMID: 6990919.
      Citations:    
    171. Talesnik J, Belo S, Israel Y. Enhancement of noradrenaline-induced metabolic coronary dilatation by ethanol. Eur J Pharmacol. 1980 Feb 08; 61(3):279-86. PMID: 7363939.
      Citations:    
    172. Khanna JM, Israel Y. Ethanol metabolism. Int Rev Physiol. 1980; 21:275-315. PMID: 6993397.
      Citations:    
    173. Orrego H, Blake JE, Blendis LM, Kapur BM, Israel Y. Reliability of assessment of alcohol intake based on personal interviews in a liver clinic. Lancet. 1979 Dec 22-29; 2(8156-8157):1354-6. PMID: 92689.
      Citations:    
    174. Israel Y. Researching the biology of alcoholism; one way of seeing it. J Stud Alcohol Suppl. 1979 Nov; 8:182-203. PMID: 293417.
      Citations:    
    175. Britton RS, Koves G, Orrego H, Kalant H, Phillips MJ, Khanna JM, Israel Y. Suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. Effect on thyroid gland or on peripheral deiodination? Toxicol Appl Pharmacol. 1979 Oct; 51(1):145-55. PMID: 93320.
      Citations:    
    176. Orrego H, Israel Y, Tiefenbach H, Saldivia V, Varghese G, Medline A. Experimental fibrogenesis: enhancement by chronic ethanol administration. Alcohol Clin Exp Res. 1979 Jul; 3(3):213-8. PMID: 384829.
      Citations:    
    177. Khanna JM, Mayer J, Orrego H, Israel Y. Effect of alpha- and beta-blockers on ethanol metabolism. Drug Alcohol Depend. 1979 Jan-Mar; 4(1-2):131-5. PMID: 510162.
      Citations:    
    178. Israel Y, Khanna JM, Orrego H, Rachamin G, Wahid S, Britton R, Macdonald A, Kalant H. Studies on metabolic tolerance to alcohol, hepatomegaly and alcoholic liver disease. Drug Alcohol Depend. 1979 Jan-Mar; 4(1-2):109-18. PMID: 510160.
      Citations:    
    179. Orrego H, Kalant H, Israel Y, Blake J, Medline A, Rankin JG, Armstrong A, Kapur B. Effect of short-term therapy with propylthiouracil in patients with alcoholic liver disease. Gastroenterology. 1979 Jan; 76(1):105-15. PMID: 758131.
      Citations:    
    180. Orrego H, Israel Y, Carmichael FJ, Khanna JM, Phillips MJ, Kalant H. Effect of dietary proteins and amino acids on liver damage induced by hypoxia. Lab Invest. 1978 Jun; 38(6):633-9. PMID: 661218.
      Citations:    
    181. Israel Y, Kalant H, Khanna JM, Orrego H, Phillips MJ, Stewart DJ. Ethanol metabolism, oxygen availability and alcohol induced liver damage. Adv Exp Med Biol. 1977; 85A:343-58. PMID: 920490.
      Citations:    
    182. Israel Y, Khanna JM, Kalant H, Stewart DJ, Macdonald JA, Rachamim G, Wahid S, Orrego H. The spontaneously hypertensive rat as a model for studies on metabolic tolerance to ethanol. Alcohol Clin Exp Res. 1977 Jan; 1(1):39-42. PMID: 337822.
      Citations:    
    183. Orrego H, Carmichael FJ, Phillips MJ, Kalant H, Khanna J, Israel Y. Protection by propylthiouracil against carbon tetrachloride-induced liver damage. Gastroenterology. 1976 Nov; 71(5):821-6. PMID: 184009.
      Citations:    
    184. Israel Y, Videla L, Bernstein J. Liver hypermetabolic state after chronic ethanol consumption: hormonal interrelations and pathogenic implications. Fed Proc. 1975 Oct; 34(11):2052-9. PMID: 1100436.
      Citations:    
    185. Carmichael FJ, Israel Y. Effects of ethanol on neurotransmitter release by rat brain cortical. J Pharmacol Exp Ther. 1975 Jun; 193(3):824-34. PMID: 239216.
      Citations:    
    186. Israel Y, Videla L, Fernandez-Videla V, Bernstein J. Effects of chronic ethanol treatment and thyroxine administration on ethanol metabolism and liver oxidative capacity. J Pharmacol Exp Ther. 1975 Mar; 192(3):565-74. PMID: 1120957.
      Citations:    
    187. Videla L, Flattery KV, Sellers EA, Israel Y. Ethanol metabolism and liver oxidative capacity in cold acclimation. J Pharmacol Exp Ther. 1975 Mar; 192(3):575-82. PMID: 123585.
      Citations:    
    188. Israel Y, Kalant H, Orrego H, Khanna JM, Videla L, Phillips JM. Experimental alcohol-induced hepatic necrosis: suppression by propylthiouracil. Proc Natl Acad Sci U S A. 1975 Mar; 72(3):1137-41. PMID: 1055371.
      Citations:    
    189. Bernstein J, Videla L, Israel Y. Hormonal influences in the development of the hypermetabolic state of the liver produced by chronic administration of ethanol. J Pharmacol Exp Ther. 1975 Mar; 192(3):583-91. PMID: 164532.
      Citations:    
    190. Israel Y, Carmichael FJ, Macdonald JA. Effects of ethanol on electrolyte metabolism and neurotransmitter release in the CNS. Adv Exp Med Biol. 1975; 59:55-64. PMID: 241216.
      Citations:    
    191. Seiden H, Israel Y, Kalant H. Activation of ethanol metabolism by 2,4-dinitrophenol in the isolated perfused rat liver. Biochem Pharmacol. 1974 Aug 15; 23(16):2234-7. PMID: 4850402.
      Citations:    
    192. Bernstein J, Videla L, Israel Y. Role of the sodium pump in the regulation of liver metabolism in experimental alcoholism. Ann N Y Acad Sci. 1974; 242(0):560-72. PMID: 4279606.
      Citations:    
    193. Carmichael FJ, Israel Y. In vitro inhibitory effects of narcotic analgesics and other psychotropic drugs on the active uptake of norepinephrine in mouse brain tissue. J Pharmacol Exp Ther. 1973 Aug; 186(2):253-60. PMID: 4719779.
      Citations:    
    194. Bernstein J, Videla L, Israel Y. Metabolic alterations produced in the liver by chronic ethanol administration. Changes related to energetic parameters of the cell. Biochem J. 1973 Jun; 134(2):515-21. PMID: 16742812.
      Citations:    
    195. Videla L, Bernstein J, Israel Y. Metabolic alterations produced in the liver by chronic ethanol administration. Increased oxidative capacity. Biochem J. 1973 Jun; 134(2):507-14. PMID: 16742811.
      Citations:    
    196. Israel Y, Videla L, Macdonald A, Bernstein J. Metabolic alterations produced in the liver by chronic ethanol administration. Comparison between the effects produced by ethanol and by thyroid hormones. Biochem J. 1973 Jun; 134(2):523-9. PMID: 16742813.
      Citations:    
    197. Israel Y, Khanna JM, Lin R. Effect of 2,4-dinitrophenol on the rate of ethanol elimination in the rat in vivo. Biochem J. 1970 Nov; 120(2):447-8. PMID: 4321897.
      Citations:    
    198. Israel Y, Kalant H, LeBlanc E, Bernstein JC, Salazar I. Changes in cation transport and (Na + K)-activated adenosine triphosphatase produced by chronic administration of ethanol. J Pharmacol Exp Ther. 1970 Aug; 174(2):330-6. PMID: 4247519.
      Citations:    
    199. Bernstein JC, Israel Y. Active transport of Rb86 in human red cells and rat brain slices. J Pharmacol Exp Ther. 1970 Aug; 174(2):323-9. PMID: 5451367.
      Citations:    
    200. Videla L, Israel Y. Factors that modify the metabolism of ethanol in rat liver and adaptive changes produced by its chronic administration. Biochem J. 1970 Jun; 118(2):275-81. PMID: 5484675.
      Citations:    
    201. Israel Y, Salazar I, Rosenmann E. Inhibitory effects of alcohol on intestinal amino acid transport in vivo and in vitro. J Nutr. 1968 Dec; 96(4):499-504. PMID: 5699991.
      Citations:    
    202. Kalant H, Israel Y, Mahon MA. The effect of ethanol on acetylcholine synthesis, release, and degradation in brain. Can J Physiol Pharmacol. 1967 Jan; 45(1):172-6. PMID: 6030395.
      Citations:    
    203. Israel Y, Kalant H, Laufer I. Effects of ethanol on na, K, mg-stimulated microsomal ATPase activity. Biochem Pharmacol. 1965 Dec; 14(12):1803-14. PMID: 4222535.
      Citations:    
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