Robert Mason

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address833 Chestnut Street
Philadelphia PA 19107
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    R13GM048230     (MASON, ROBERT W)Sep 1, 1992 - Aug 31, 1993
    NIH
    CONFERENCE ON PROTEOLYSIS AND PROTEIN TURNOVER
    Role: Principal Investigator

    R01GM059183     (MASON, ROBERT W)Feb 1, 2000 - Jan 31, 2004
    NIH
    PROBING FOR PROTEASES IN CELLULAR COMPARTMENTS
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Halakos EG, Connell AJ, Glazewski L, Wei S, Mason RW. Bottom up proteomics identifies neuronal differentiation pathway networks activated by cathepsin inhibition treatment in neuroblastoma cells that are enhanced by concurrent 13-cis retinoic acid treatment. J Proteomics. 2021 02 10; 232:104068. PMID: 33278663.
      Citations:    
    2. Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Hum Mol Genet. 2020 07 29; 29(12):2076-2097. PMID: 32420594.
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    3. Arunkumar N, Langan TJ, Stapleton M, Kubaski F, Mason RW, Singh R, Kobayashi H, Yamaguchi S, Suzuki Y, Orii K, Orii T, Fukao T, Tomatsu S. Newborn screening of mucopolysaccharidoses: past, present, and future. J Hum Genet. 2020 Jul; 65(7):557-567. PMID: 32277174.
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    4. Khan SA, Mason RW, Kobayashi H, Yamaguchi S, Tomatsu S. Advances in glycosaminoglycan detection. Mol Genet Metab. 2020 06; 130(2):101-109. PMID: 32247585.
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    5. Stapleton M, Kubaski F, Mason RW, Shintaku H, Kobayashi H, Yamaguchi S, Taketani T, Suzuki Y, Orii K, Orii T, Fukao T, Tomatsu S. Newborn screening for mucopolysaccharidoses: Measurement of glycosaminoglycans by LC-MS/MS. Mol Genet Metab Rep. 2020 Mar; 22:100563. PMID: 31956510.
      Citations:    
    6. Halakos EG, Connell AJ, Glazewski L, Wei S, Mason RW. Bottom up proteomics reveals novel differentiation proteins in neuroblastoma cells treated with 13-cis retinoic acid. J Proteomics. 2019 10 30; 209:103491. PMID: 31472280.
      Citations:    
    7. Chen HH, Sawamoto K, Mason RW, Kobayashi H, Yamaguchi S, Suzuki Y, Orii K, Orii T, Tomatsu S. Enzyme replacement therapy for mucopolysaccharidoses; past, present, and future. J Hum Genet. 2019 Nov; 64(11):1153-1171. PMID: 31455839.
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    8. Doherty C, Stapleton M, Piechnik M, Mason RW, Mackenzie WG, Yamaguchi S, Kobayashi H, Suzuki Y, Tomatsu S. Effect of enzyme replacement therapy on the growth of patients with Morquio A. J Hum Genet. 2019 Jul; 64(7):625-635. PMID: 31019230.
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    9. Taylor M, Khan S, Stapleton M, Wang J, Chen J, Wynn R, Yabe H, Chinen Y, Boelens JJ, Mason RW, Kubaski F, Horovitz DDG, Barth AL, Serafini M, Bernardo ME, Kobayashi H, Orii KE, Suzuki Y, Orii T, Tomatsu S. Hematopoietic Stem Cell Transplantation for Mucopolysaccharidoses: Past, Present, and Future. Biol Blood Marrow Transplant. 2019 07; 25(7):e226-e246. PMID: 30772512.
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    10. Fujitsuka H, Sawamoto K, Peracha H, Mason RW, Mackenzie W, Kobayashi H, Yamaguchi S, Suzuki Y, Orii K, Orii T, Fukao T, Tomatsu S. Biomarkers in patients with mucopolysaccharidosis type II and IV. Mol Genet Metab Rep. 2019 Jun; 19:100455. PMID: 30775257.
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    11. Stapleton M, Hoshina H, Sawamoto K, Kubaski F, Mason RW, Mackenzie WG, Theroux M, Kobayashi H, Yamaguchi S, Suzuki Y, Fukao T, Tadao O, Ida H, Tomatsu S. Critical review of current MPS guidelines and management. Mol Genet Metab. 2019 03; 126(3):238-245. PMID: 30143438.
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    12. Khan SA, Mason RW, Giugliani R, Orii K, Fukao T, Suzuki Y, Yamaguchi S, Kobayashi H, Orii T, Tomatsu S. Glycosaminoglycans analysis in blood and urine of patients with mucopolysaccharidosis. Mol Genet Metab. 2018 09; 125(1-2):44-52. PMID: 29779903.
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    13. Melbouci M, Mason RW, Suzuki Y, Fukao T, Orii T, Tomatsu S. Growth impairment in mucopolysaccharidoses. Mol Genet Metab. 2018 05; 124(1):1-10. PMID: 29627275.
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    14. Nagao K, Morlet T, Haley E, Padilla J, Nemith J, Mason RW, Tomatsu S. Neurophysiology of hearing in patients with mucopolysaccharidosis type IV. Mol Genet Metab. 2018 04; 123(4):472-478. PMID: 29472067.
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    15. Stapleton M, Arunkumar N, Kubaski F, Mason RW, Tadao O, Tomatsu S. Clinical presentation and diagnosis of mucopolysaccharidoses. Mol Genet Metab. 2018 09; 125(1-2):4-17. PMID: 30057281.
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    16. Sawamoto K, Chen HH, Alm?ciga-D?az CJ, Mason RW, Tomatsu S. Gene therapy for Mucopolysaccharidoses. Mol Genet Metab. 2018 02; 123(2):59-68. PMID: 29295764.
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    17. Doherty C, Averill LW, Theroux M, Mackenzie WG, Pizarro C, Mason RW, Tomatsu S. Natural history of Morquio A patient with tracheal obstruction from birth to death. Mol Genet Metab Rep. 2018 Mar; 14:59-67. PMID: 29326877.
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    18. Kubaski F, Yabe H, Suzuki Y, Seto T, Hamazaki T, Mason RW, Xie L, Onsten TGH, Leistner-Segal S, Giugliani R, Dung VC, Ngoc CTB, Yamaguchi S, Monta?o AM, Orii KE, Fukao T, Shintaku H, Orii T, Tomatsu S. Hematopoietic Stem Cell Transplantation for Patients with Mucopolysaccharidosis II. Biol Blood Marrow Transplant. 2017 Oct; 23(10):1795-1803. PMID: 28673849.
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    19. Stapleton M, Sawamoto K, Alm?ciga-D?az CJ, Mackenzie WG, Mason RW, Orii T, Tomatsu S. Development of Bone Targeting Drugs. Int J Mol Sci. 2017 Jun 23; 18(7). PMID: 28644392.
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    20. Khan SA, Peracha H, Ballhausen D, Wiesbauer A, Rohrbach M, Gautschi M, Mason RW, Giugliani R, Suzuki Y, Orii KE, Orii T, Tomatsu S. Epidemiology of mucopolysaccharidoses. Mol Genet Metab. 2017 07; 121(3):227-240. PMID: 28595941.
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    21. Kubaski F, Brusius-Facchin AC, Mason RW, Patel P, Burin MG, Michelin-Tirelli K, Kessler RG, Bender F, Leistner-Segal S, Moreno CA, Cavalcanti DP, Giugliani R, Tomatsu S. Elevation of glycosaminoglycans in the amniotic fluid of a fetus with mucopolysaccharidosis VII. Prenat Diagn. 2017 May; 37(5):435-439. PMID: 28207930.
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    22. Stapleton M, Kubaski F, Mason RW, Yabe H, Suzuki Y, Orii KE, Orii T, Tomatsu S. Presentation and Treatments for Mucopolysaccharidosis Type II (MPS II; Hunter Syndrome). Expert Opin Orphan Drugs. 2017; 5(4):295-307. PMID: 29158997.
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    23. Sampson VB, Vetter NS, Zhang W, Patil PU, Mason RW, George E, Gorlick R, Kolb EA. Integrating mechanisms of response and resistance against the tubulin binding agent Eribulin in preclinical models of osteosarcoma. Oncotarget. 2016 Dec 27; 7(52):86594-86607. PMID: 27863409.
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    24. Kubaski F, Suzuki Y, Orii K, Giugliani R, Church HJ, Mason RW, Dung VC, Ngoc CT, Yamaguchi S, Kobayashi H, Girisha KM, Fukao T, Orii T, Tomatsu S. Glycosaminoglycan levels in dried blood spots of patients with mucopolysaccharidoses and mucolipidoses. Mol Genet Metab. 2017 03; 120(3):247-254. PMID: 28065440.
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    25. Khan S, Alm?ciga-D?az CJ, Sawamoto K, Mackenzie WG, Theroux MC, Pizarro C, Mason RW, Orii T, Tomatsu S. Mucopolysaccharidosis IVA and glycosaminoglycans. Mol Genet Metab. 2017 Jan - Feb; 120(1-2):78-95. PMID: 27979613.
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    26. Kubaski F, Mason RW, Nakatomi A, Shintaku H, Xie L, van Vlies NN, Church H, Giugliani R, Kobayashi H, Yamaguchi S, Suzuki Y, Orii T, Fukao T, Monta?o AM, Tomatsu S. Newborn screening for mucopolysaccharidoses: a pilot study of measurement of glycosaminoglycans by tandem mass spectrometry. J Inherit Metab Dis. 2017 01; 40(1):151-158. PMID: 27718145.
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    27. Kubaski F, Osago H, Mason RW, Yamaguchi S, Kobayashi H, Tsuchiya M, Orii T, Tomatsu S. Glycosaminoglycans detection methods: Applications of mass spectrometry. Mol Genet Metab. 2017 Jan - Feb; 120(1-2):67-77. PMID: 27746032.
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    28. Sawamoto K, Suzuki Y, Mackenzie WG, Theroux MC, Pizarro C, Yabe H, Orii KE, Mason RW, Orii T, Tomatsu S. Current therapies for Morquio A syndrome and their clinical outcomes. Expert Opin Orphan Drugs. 2016; 4(9):941-951. PMID: 28217429.
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    29. Gopalakrishnapillai A, Kolb EA, Dhanan P, Bojja AS, Mason RW, Corao D, Barwe SP. Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice. Front Oncol. 2016; 6:162. PMID: 27446808.
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    30. Yasuda E, Suzuki Y, Shimada T, Sawamoto K, Mackenzie WG, Theroux MC, Pizarro C, Xie L, Miller F, Rahman T, Kecskemethy HH, Nagao K, Morlet T, Shaffer TH, Chinen Y, Yabe H, Tanaka A, Shintaku H, Orii KE, Orii KO, Mason RW, Monta?o AM, Fukao T, Orii T, Tomatsu S. Activity of daily living for Morquio A syndrome. Mol Genet Metab. 2016 06; 118(2):111-22. PMID: 27161890.
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    31. Cies JJ, Moore WS, Chopra A, Lu G, Mason RW. Stability of furosemide and chlorothiazide stored in syringes. Am J Health Syst Pharm. 2015 Dec 15; 72(24):2182-8. PMID: 26637518.
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    32. Soori M, Lu G, Mason RW. Cathepsin Inhibition Prevents Autophagic Protein Turnover and Downregulates Insulin Growth Factor-1 Receptor-Mediated Signaling in Neuroblastoma. J Pharmacol Exp Ther. 2016 Feb; 356(2):375-86. PMID: 26660229.
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    33. Tomatsu S, Sawamoto K, Shimada T, Bober MB, Kubaski F, Yasuda E, Mason RW, Khan S, Alm?ciga-D?az CJ, Barrera LA, Mackenzie WG, Orii T. Enzyme replacement therapy for treating mucopolysaccharidosis type IVA (Morquio A syndrome): effect and limitations. Expert Opin Orphan Drugs. 2015 Nov 01; 3(11):1279-1290. PMID: 26973801.
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    34. Patil PU, D'Ambrosio J, Inge LJ, Mason RW, Rajasekaran AK. Carcinoma cells induce lumen filling and EMT in epithelial cells through soluble E-cadherin-mediated activation of EGFR. J Cell Sci. 2015 Dec 01; 128(23):4366-79. PMID: 26483386.
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    35. Gopalakrishnapillai A, Kolb EA, Dhanan P, Mason RW, Napper A, Barwe SP. Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy. PLoS One. 2015; 10(10):e0140564. PMID: 26465153.
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    36. Krishnan V, Xu X, Kelly D, Snook A, Waldman SA, Mason RW, Jia X, Rajasekaran AK. CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia. Mol Pharm. 2015 Jun 1; 12(6):2101-11. PMID: 25898125.
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    37. Tomatsu S, Sawamoto K, Alm?ciga-D?az CJ, Shimada T, Bober MB, Chinen Y, Yabe H, Monta?o AM, Giugliani R, Kubaski F, Yasuda E, Rodr?guez-L?pez A, Espejo-Mojica AJ, S?nchez OF, Mason RW, Barrera LA, Mackenzie WG, Orii T. Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome. Drug Des Devel Ther. 2015; 9:1937-53. PMID: 25897204.
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    38. Yasuda E, Mackenzie W, Ruhnke K, Shimada T, Mason RW, Zustin J, Martin PL, Thacker M, Orii T, Sai Y, Tomatsu S. Molecular Genetics and Metabolism Report Long-term follow-up of post hematopoietic stem cell transplantation for Hurler syndrome: clinical, biochemical, and pathological improvements. Mol Genet Metab Rep. 2015 Mar; 2:65-76. PMID: 25709894.
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    39. Shimada T, Tomatsu S, Mason RW, Yasuda E, Mackenzie WG, Hossain J, Shibata Y, Monta?o AM, Kubaski F, Giugliani R, Yamaguchi S, Suzuki Y, Orii KE, Fukao T, Orii T. Di-sulfated Keratan Sulfate as a Novel Biomarker for Mucopolysaccharidosis II, IVA, and IVB. JIMD Rep. 2015; 21:1-13. PMID: 25712379.
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    40. Tomatsu S, Alm?ciga-D?az CJ, Monta?o AM, Yabe H, Tanaka A, Dung VC, Giugliani R, Kubaski F, Mason RW, Yasuda E, Sawamoto K, Mackenzie W, Suzuki Y, Orii KE, Barrera LA, Sly WS, Orii T. Therapies for the bone in mucopolysaccharidoses. Mol Genet Metab. 2015 Feb; 114(2):94-109. PMID: 25537451.
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    41. Tanjuakio J, Suzuki Y, Patel P, Yasuda E, Kubaski F, Tanaka A, Yabe H, Mason RW, Monta?o AM, Orii KE, Orii KO, Fukao T, Orii T, Tomatsu S. Activities of daily living in patients with Hunter syndrome: impact of enzyme replacement therapy and hematopoietic stem cell transplantation. Mol Genet Metab. 2015 Feb; 114(2):161-9. PMID: 25468646.
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    42. Tomatsu S, Shimada T, Mason RW, Monta?o AM, Kelly J, LaMarr WA, Kubaski F, Giugliani R, Guha A, Yasuda E, Mackenzie W, Yamaguchi S, Suzuki Y, Orii T. Establishment of glycosaminoglycan assays for mucopolysaccharidoses. Metabolites. 2014 Aug 11; 4(3):655-79. PMID: 25116756.
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    43. Shimada T, Kelly J, LaMarr WA, van Vlies N, Yasuda E, Mason RW, Mackenzie W, Kubaski F, Giugliani R, Chinen Y, Yamaguchi S, Suzuki Y, Orii KE, Fukao T, Orii T, Tomatsu S. Novel heparan sulfate assay by using automated high-throughput mass spectrometry: Application to monitoring and screening for mucopolysaccharidoses. Mol Genet Metab. 2014 Sep-Oct; 113(1-2):92-9. PMID: 25092413.
      Citations:    
    44. Shimada T, Tomatsu S, Yasuda E, Mason RW, Mackenzie WG, Shibata Y, Kubaski F, Giugliani R, Yamaguchi S, Suzuki Y, Orii K, Orii T. Chondroitin 6-Sulfate as a Novel Biomarker for Mucopolysaccharidosis IVA and VII. JIMD Rep. 2014; 16:15-24. PMID: 24850234.
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    45. Tomatsu S, Shimada T, Mason RW, Kelly J, LaMarr WA, Yasuda E, Shibata Y, Futatsumori H, Monta?o AM, Yamaguchi S, Suzuki Y, Orii T. Assay for Glycosaminoglycans by Tandem Mass Spectrometry and its Applications. J Anal Bioanal Tech. 2014 Mar 01; 2014(Suppl 2):006. PMID: 25068074.
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    46. Patel P, Suzuki Y, Tanaka A, Yabe H, Kato S, Shimada T, Mason RW, Orii KE, Fukao T, Orii T, Tomatsu S. Impact of Enzyme Replacement Therapy and Hematopoietic Stem Cell Therapy on Growth in Patients with Hunter Syndrome. Mol Genet Metab Rep. 2014; 1:184-196. PMID: 25061571.
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    47. Tomatsu S, Kubaski F, Sawamoto K, Mason RW, Yasuda E, Shimada T, Monta?o AM, Yamaguchi S, Suzuki Y, Orii T. Newborn screening and diagnosis of mucopolysaccharidoses: application of tandem mass spectrometry. Nihon Masu Sukuriningu Gakkai Shi. 2014; 24:19-37. PMID: 25620850.
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    48. Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK. Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb; 131:86-110. PMID: 24161570.
      Citations:    
    49. Tomatsu S, Alm?ciga-D?az CJ, Barbosa H, Monta?o AM, Barrera LA, Shimada T, Yasuda E, Mackenzie WG, Mason RW, Suzuki Y, Orii KE, Orii T. Therapies of mucopolysaccharidosis IVA (Morquio A syndrome). Expert Opin Orphan Drugs. 2013 Oct 01; 1(10):805-818. PMID: 25419501.
      Citations:    
    50. Tomatsu S, Fujii T, Fukushi M, Oguma T, Shimada T, Maeda M, Kida K, Shibata Y, Futatsumori H, Monta?o AM, Mason RW, Yamaguchi S, Suzuki Y, Orii T. Newborn screening and diagnosis of mucopolysaccharidoses. Mol Genet Metab. 2013 Sep-Oct; 110(1-2):42-53. PMID: 23860310.
      Citations:    
    51. Tomatsu S, Mackenzie WG, Theroux MC, Mason RW, Thacker MM, Shaffer TH, Monta?o AM, Rowan D, Sly W, Alm?ciga-D?az CJ, Barrera LA, Chinen Y, Yasuda E, Ruhnke K, Suzuki Y, Orii T. Current and emerging treatments and surgical interventions for Morquio A syndrome: a review. Res Rep Endocr Disord. 2012 Dec; 2012(2):65-77. PMID: 24839594.
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    52. Krishnan V, Xu X, Barwe SP, Yang X, Czymmek K, Waldman SA, Mason RW, Jia X, Rajasekaran AK. Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine. Mol Pharm. 2013 Jun 3; 10(6):2199-210. PMID: 23194373.
      Citations:    
    53. Wu CY, Whye D, Mason RW, Wang W. Efficient differentiation of mouse embryonic stem cells into motor neurons. J Vis Exp. 2012 Jun 09; (64):e3813. PMID: 22711008.
      Citations:    
    54. Cartledge DM, Colella R, Glazewski L, Lu G, Mason RW. Inhibitors of cathepsins B and L induce autophagy and cell death in neuroblastoma cells. Invest New Drugs. 2013 Feb; 31(1):20-9. PMID: 22549440.
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    55. Wu CY, Curtis A, Choi YS, Maeda M, Xu MJ, Berg A, Joneja U, Mason RW, Lee KH, Wang W. Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A. Biochim Biophys Acta. 2011 Sep; 1814(9):1134-9. PMID: 21609790.
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    56. Wu CY, Whye D, Glazewski L, Choe L, Kerr D, Lee KH, Mason RW, Wang W. Proteomic assessment of a cell model of spinal muscular atrophy. BMC Neurosci. 2011; 12:25. PMID: 21385431.
      Citations:    
    57. Colella R, Lu G, Glazewski L, Korant B, Matlapudi A, England MR, Craft C, Frantz CN, Mason RW. Induction of cell death in neuroblastoma by inhibition of cathepsins B and L. Cancer Lett. 2010 Aug 28; 294(2):195-203. PMID: 20362389.
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    58. Hassanein M, Xue F, Seto CT, Mason RW. Development of a specific inhibitor for the placental protease, cathepsin P. Arch Biochem Biophys. 2007 Aug 15; 464(2):288-94. PMID: 17531191.
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    59. Puzer L, Barros NM, Oliveira V, Juliano MA, Lu G, Hassanein M, Juliano L, Mason RW, Carmona AK. Defining the substrate specificity of mouse cathepsin P. Arch Biochem Biophys. 2005 Mar 01; 435(1):190-6. PMID: 15680921.
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    60. Mason RW, Hopp L, Lloyd JB. Nitric oxide does not mediate promotion of cellular potassium release by phenolphthalein in COS-7 cells. Clin Exp Pharmacol Physiol. 2004 Apr; 31(4):271-3. PMID: 15053826.
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    61. Mason RW, Bergman CA, Lu G, Frenck Holbrook J, Sol-Church K. Expression and characterization of cathepsin P. Biochem J. 2004 Mar 01; 378(Pt 2):657-63. PMID: 14629193.
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    62. Mason RW, Simpson-Small T, Hopp L. Regulation of 86Rb+ ion transport across polarized human colonocytes by bis-phenolic compounds. Clin Exp Pharmacol Physiol. 2003 Sep; 30(9):623-6. PMID: 12940878.
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