Marc Spirn

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19107
Phone2152334300
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Safran JP, Momenaei B, Martin J, Crain B, Richards C, Kaiser R, Garg SJ, Sivalingam A, Spirn M, Hsu J. Rhegmatogenous Retinal Detachment Following Vitrectomy and Subretinal Tissue Plasminogen Activator for Submacular Hemorrhage. Retina. 2025 Jan 29. PMID: 39903912.
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    2. Durrani AF, Momenaei B, Soni V, Tennant M, Hsu J, Vander J, Spirn M, Kang EY, Hwang YS, Kaushal G, Garg SJ. Long-Term Stability, Sterility, And Cost-Effectiveness of 0.05% Chlorhexidine Gluconate as Antisepsis for Intravitreal Injection. J Ocul Pharmacol Ther. 2024 Aug 22. PMID: 39169875.
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    3. Kazan AS, Mahmoudzadeh R, Salabati M, Sharpe J, Fineman MS, Hsu J, Yonekawa Y, Spirn MJ. Indications and Outcomes of Laser Retinopexy in Eyes With High-Risk Lattice Degeneration. J Vitreoretin Dis. 2024 Jul-Aug; 8(4):381-387. PMID: 39148566.
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    4. Durrani AF, Momenaei B, Wakabayashi T, Vemula S, Pandit SA, Hsu J, Ho AC, Spirn MJ, Klufas MA, Garg SJ, Vander JF, Regillo CD, Chiang A, Kuriyan AE, Yonekawa Y. Conversion to faricimab after prior anti-vascular endothelial growth factor therapy for persistent diabetic macular oedema. Br J Ophthalmol. 2024 Feb 12. PMID: 38346854.
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    5. Park JG, Adrean SD, Begaj T, Capone A, Charles S, Chen SN, Chou HD, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Lai CC, Mahgoub MM, Mansoor M, Matoba R, Morizane Y, Nehemy MB, Raphaelian PV, Regillo CD, Ruby AJ, Runner MM, Sneed SR, Sohn EH, Spirn MJ, Vander JF, Wakabayashi T, Wolfe JD, Wykoff CC, Yonekawa Y, Yoon YH, Mahmoud TH. Surgical Management of Full Thickness Macular Holes in Macular Telangiectasia Type 2.A Global Multicenter Study. Ophthalmology. 2023 Sep 01. PMID: 37661066.
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    6. Israilevich RN, Syed ZA, Xu D, Kaiser RS, Garg SJ, Spirn MJ, Mehta S, Gupta OP, Ho AC, Kuriyan AE, Yonekawa Y, Starr MR. Neurotrophic keratopathy following rhegmatogenous retinal detachment surgery. Can J Ophthalmol. 2023 Jun 14. PMID: 37330215.
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    7. Wakabayashi T, Patel N, Bough M, Nahar A, Sheng Y, Momenaei B, Salabati M, Mahmoudzadeh R, Kuriyan AE, Spirn MJ, Chiang A, Hsu J, Fineman MS, Regillo CD, Sivalingam A, Ho AC, Gupta OP, Yonekawa Y. Vitrectomy for Vitreous Hemorrhage Associated with Retinal Vein Occlusion: Visual Outcomes, Prognostic Factors, and Sequelae. Retina. 2023 Jun 05. PMID: 37294906.
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    8. Swaminathan VB, Salabati M, Israilevich R, Cehelyk E, Mahmoudzadeh R, Uhr JH, Spirn MJ, Klufas MA, Garg SJ, Hsu J. Outcomes following repair of early-onset versus delayed-onset rhegmatogenous retinal detachments after acute posterior vitreous detachment. Br J Ophthalmol. 2023 Mar 14. PMID: 36918274.
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    9. Cobbs LV, Soares RR, Spirn M, Mehta S. Premature Emulsification of Silicone Oil After Retinal Detachment Repair in the Setting of High-Intensity Exercise. Retin Cases Brief Rep. 2023 Mar 09. PMID: 36913668.
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    10. Massenzio E, Xu D, Abishek R, Wibbelsman TD, Sheng Y, Obeid A, Bhatt S, Zhang Q, Sharpe J, Park CH, Spirn MJ, Gupta OP, Chiang A, Shukla A, Shalaby WS, Myers JS, Hsu J. Risk Factors for Surgery or Blindness in Neovascular Glaucoma Eyes Treated with Anti-VEGF Injections by a Retina Specialist. Retina. 2023 Mar 09. PMID: 36913629.
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    11. Starr MR, Boucher N, Sharma C, Wakabayashi T, Sivalingam M, Klufas MA, Spirn M, Yonekawa Y. The State of Pediatric Retinal Detachment Surgery in the United States: a Nationwide Aggregated Health Record Analysis. Retina. 2023 Jan 10. PMID: 36728195.
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    12. Wakabayashi T, Liu CK, Anderson HE, Mahmoudzadeh R, Nguyen MK, Salabati M, Chiang A, Hsu J, Garg SJ, Spirn MJ. A Comparison of Ocular Complications after 0.7 mg Dexamethasone Implant versus 2 mg of Intravitreal Triamcinolone in Vitrectomized Eyes. Ophthalmol Retina. 2022 Dec 23. PMID: 36572383.
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    13. Wakabayashi T, Mahmoudzadeh R, Salabati M, Garg SJ, Ho AC, Spirn MJ. Utility of Removal of Vitreous Cortex Remnants during Vitrectomy for Primary Rhegmatogenous Retinal Detachment Repair. Curr Eye Res. 2022 10; 47(10):1444-1449. PMID: 35838170.
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    14. Salabati M, Obeid A, Mahmoudzadeh R, Gupta O, Chiang A, Spirn M, Klufas MA, Hsu J. Outcomes after switching eyes that were stable on aflibercept to ranibizumab versus continuing aflibercept in neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2022 Aug; 260(8):2509-2516. PMID: 35230472.
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    15. Uhr JH, Storey PP, Kuley B, Patel SN, Wibbelsman TD, Pancholy M, Spirn MJ. THE EFFECT OF ENDOPHTHALMITIS ON RECURRENCE OF MACULAR EDEMA IN EYES RECEIVING INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR. Retina. 2021 Jul 01; 41(7):1470-1477. PMID: 33252583.
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    16. Starr MR, Huang D, Israilevich RN, Ammar MJ, Patel LG, Gupta OP, Fineman MS, Hsu J, Kaiser RS, Kuriyan AE, Mehta S, Park CH, Spirn MJ, Martin SD, Chatterjee A, Lee D, Pro MJ, Moster MR, Garg SJ, Yonekawa Y. Endophthalmitis after Minimally Invasive Glaucoma Surgery. Ophthalmology. 2021 12; 128(12):1777-1779. PMID: 34102231.
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    17. Pancholy M, Storey PP, Levin HJ, Obeid A, Patel SN, Kuley B, Hsu J, Spirn MJ, Fineman M, Klufas MA, Gupta O, Ho AC, Garg SJ. Endophthalmitis following Intravitreal Anti-Vascular Endothelial Growth Factor Therapy: Changes in Incidence and Outcomes over a 9-Year Period. Curr Eye Res. 2021 09; 46(9):1370-1377. PMID: 33522314.
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    18. Kuley B, Storey PP, Wibbelsman TD, Pancholy M, Zhang QE, Sharpe J, Bello N, Obeid A, Regillo C, Kaiser RS, Chiang A, Fineman MS, Vander JF, Gupta OP, Spirn MJ, Dunn JP, Mehta S, Park CH, Maguire JI, Garg S. Resolution of Pseudophakic Cystoid Macular Edema: 2 mg Intravitreal Triamcinolone Acetonide versus 40 mg Posterior Sub-Tenon Triamcinolone Acetonide. Curr Eye Res. 2021 06; 46(6):824-830. PMID: 33522311.
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    19. Mellen PL, Obeid A, Wibbelsman TD, Hsu J, Konkoly MA, Velez MR, Calem DB, Sioufi K, Jenkins TL, Xu D, Chiang A, Gupta OP, Spirn M, Regillo CD, Ho AC, Klufas MA. Clinical Outcomes of Eyes With Diabetic Macular Edema Switched From Aflibercept to Ranibizumab Therapy. Ophthalmic Surg Lasers Imaging Retina. 2020 12 01; 51(12):691-697. PMID: 33339050.
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    20. Hsu J, Patel SN, Wolfe JD, Shah CP, Chen E, Jenkins TL, Wibbelsman TD, Obeid A, Mikhail M, Garg SJ, Ho AC, Chiang A, Spirn MJ, Vander JF. Effect of Adjuvant Topical Dorzolamide-Timolol vs Placebo in Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial. JAMA Ophthalmol. 2020 05 01; 138(5):560-567. PMID: 32239190.
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    21. Uhr JH, Obeid A, Wibbelsman TD, Wu CM, Levin HJ, Garrigan H, Spirn MJ, Chiang A, Sivalingam A, Hsu J. Delayed Retinal Breaks and Detachments after Acute Posterior Vitreous Detachment. Ophthalmology. 2020 Apr; 127(4):516-522. PMID: 31767432.
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    22. Thau A, Tsukikawa M, Wangtiraumnuay N, Capasso J, Affel E, Alnabi WA, Adam M, Alsulaiman SM, Spirn M, Levin AV. Optical Coherence Tomography in Knobloch Syndrome. Ophthalmic Surg Lasers Imaging Retina. 2019 08 01; 50(8):e203-e210. PMID: 31415705.
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    23. Sioufi K, Talcott KE, Spirn MJ. Unilateral macular drusen in a young female. Indian J Ophthalmol. 2018 Nov; 66(11):1531. PMID: 30355856.
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    24. London NJS, Kaiser RS, Khan MA, Alshareef RA, Khuthaila M, Shahlaee A, Obeid A, London VA, DeCroos FC, Gupta OP, Hsu J, Vander JF, Spirn MJ, Regillo CD. Determining the effect of low-dose isotretinoin on proliferative vitreoretinopathy: the DELIVER trial. Br J Ophthalmol. 2019 09; 103(9):1306-1313. PMID: 30381390.
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    25. Sridhar J, Kasi S, Paul J, Shahlaee A, Rahimy E, Chiang A, Spirn MJ, Hsu J, Garg SJ. A PROSPECTIVE, RANDOMIZED TRIAL COMPARING PLAIN GUT TO POLYGLACTIN 910 (VICRYL) SUTURES FOR SCLEROTOMY CLOSURE AFTER 23-GAUGE PARS PLANA VITRECTOMY. Retina. 2018 Jun; 38(6):1216-1219. PMID: 28492428.
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    26. Rahimy E, Pitcher JD, Hsu J, Adam MK, Shahlaee A, Samara WA, Vander JF, Kaiser RS, Chiang A, Spirn MJ, Fineman MS. A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROL PILOT STUDY OF EPLERENONE FOR THE TREATMENT OF CENTRAL SEROUS CHORIORETINOPATHY (ECSELSIOR). Retina. 2018 May; 38(5):962-969. PMID: 28426624.
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    27. Tam EK, Golchet P, Yung M, DeCroos FC, Spirn M, Lehmann-Clarke L, Ambresin A, Tsui I. ISCHEMIC CENTRAL RETINAL VEIN OCCLUSION IN THE ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ERA. Retina. 2018 Feb; 38(2):292-298. PMID: 28207609.
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    28. Khan MA, Ho AC, Spirn MJ. COTTON-WOOL SPOTS AFTER USE OF MACITENTAN FOR PULMONARY ARTERIAL HYPERTENSION. Retin Cases Brief Rep. 2017 Winter; 11(1):4-6. PMID: 26829448.
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    29. Gensure RH, Hsu J, Federman J, Park C, Spirn MJ. COAGULASE-NEGATIVE STAPHYLOCOCCUS-INDUCED FROSTED BRANCH ANGIITIS AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION. Retin Cases Brief Rep. 2017 Winter; 11(1):60-62. PMID: 26954782.
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    30. Sridhar J, Hsu J, Shahlaee A, Garg SJ, Spirn MJ, Fineman MS, Vander J. Topical Dorzolamide-Timolol With Intravitreous Anti-Vascular Endothelial Growth Factor for Neovascular Age-Related Macular Degeneration. JAMA Ophthalmol. 2016 Apr; 134(4):437-43. PMID: 26914218.
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    31. Khan MA, Gupta OP, Smith RG, Ayres BD, Raber IM, Bailey RS, Hsu J, Spirn MJ. Scleral fixation of intraocular lenses using Gore-Tex suture: clinical outcomes and safety profile. Br J Ophthalmol. 2016 May; 100(5):638-43. PMID: 26319945.
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    32. Adam MK, Vahedi S, Nichols MM, Fintelmann RE, Keenan JD, Garg SJ, Hsu J, Maguire JI, Spirn MJ. Inpatient Ophthalmology Consultation for Fungemia: Prevalence of Ocular Involvement and Necessity of Funduscopic Screening. Am J Ophthalmol. 2015 Nov; 160(5):1078-1083.e2. PMID: 26235339.
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    33. Adam MK, Brady CJ, Flowers AM, Juhn AT, Hsu J, Garg SJ, Murchison AP, Spirn MJ. Quality and Diagnostic Utility of Mydriatic Smartphone Photography: The Smartphone Ophthalmoscopy Reliability Trial. Ophthalmic Surg Lasers Imaging Retina. 2015 Jun; 46(6):631-7. PMID: 26114843.
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    34. Rayess N, Rahimy E, Vander JF, Spirn MJ, Chiang A, Garg SJ, Hsu J. Spectral-Domain Optical Coherence Tomography in Acute Posterior Vitreous Detachment. Ophthalmology. 2015 Sep; 122(9):1946-7. PMID: 25935788.
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    35. Salz DA, Pitcher JD, Hsu J, Regillo CD, Fineman MS, Elliott KS, Vander JF, Fischer DH, Spirn MJ. Oral eplerenone for treatment of chronic central serous chorioretinopathy: a case series. Ophthalmic Surg Lasers Imaging Retina. 2015 Apr; 46(4):439-44. PMID: 25970864.
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    36. Rahimy E, Fineman MS, Regillo CD, Spirn MJ, Hsu J, Kaiser RS, Maguire JI, Brown GC, Chiang A. Speculum versus Bimanual Lid Retraction during Intravitreal Injection. Ophthalmology. 2015 Aug; 122(8):1729-30. PMID: 25726752.
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    37. Adam MK, Rahimy E, Brady CJ, Aronsky M, Hsu J, Spirn M. Endophthalmitis after penetrating ocular injury in the dentist's chair. Can J Ophthalmol. 2014 Dec; 49(6):e154-6. PMID: 25433754.
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    38. Hsu J, Gerstenblith AT, London NJ, Garg SJ, Spirn MJ, Maguire JI, Park C, Sivalingam A. Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment. Retina. 2014 Dec; 34(12):2458-61. PMID: 25072647.
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    39. Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ, Hubschman JP, Davis JL, Heilwell G, Spirn M, Maguire J, Gay R, Bateman J, Ostrick RM, Morris D, Vincent M, Anglade E, Del Priore LV, Lanza R. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies. Lancet. 2015 Feb 07; 385(9967):509-16. PMID: 25458728.
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    40. DeCroos FC, Todorich B, Alshareef R, Khuthaila M, Fekrat S, Ho AC, Regillo CD, Spirn MJ. Neovascular events in eyes with central retinal vein occlusion undergoing serial bevacizumab or ranibizumab intravitreal injections: a retrospective review. J Ophthalmic Vis Res. 2014 Oct-Dec; 9(4):461-8. PMID: 25709772.
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    41. Khan MA, Gerstenblith AT, Dollin ML, Gupta OP, Spirn MJ. Scleral fixation of posterior chamber intraocular lenses using gore-tex suture with concurrent 23-gauge pars plana vitrectomy. Retina. 2014 Jul; 34(7):1477-80. PMID: 24949717.
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    42. Alshareef RA, Garg SJ, Hsu J, Vander J, Park C, Spirn MJ. Intravitreal triamcinolone acetonide injection for macular edema due to central retinal vein occlusion persisting despite multiple intravitreal bevacizumab injections. J Ocul Pharmacol Ther. 2014 Aug; 30(6):512-6. PMID: 24828198.
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    43. Fineman MS, Hsu J, Spirn MJ, Kaiser RS. Reply: To PMID 23609121. Retina. 2014 Apr; 34(4):e13. PMID: 24796006.
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    44. Rasouli M, Khuthaila M, Spirn MJ, Garg SJ, Greve MD, Hsu J. Outcomes of scleral buckle removal with and without concurrent prophylactic laser retinopexy. Can J Ophthalmol. 2014 Feb; 49(1):30-4. PMID: 24513353.
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    45. Fineman MS, Hsu J, Spirn MJ, Kaiser RS. Bimanual assisted eyelid retraction technique for intravitreal injections. Retina. 2013 Oct; 33(9):1968-70. PMID: 23609121.
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    46. Khuthaila MK, Hsu J, Chiang A, DeCroos FC, Milder EA, Setlur V, Garg SJ, Spirn MJ. Postoperative vitreous hemorrhage after diabetic 23-gauge pars plana vitrectomy. Am J Ophthalmol. 2013 Apr; 155(4):757-63, 763.e1-2. PMID: 23317651.
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    47. Chiang A, Garg SJ, Alshareef RA, Pitcher JD, Hu AY, Spirn MJ, Hsu J, Lane RG, Regillo CD, Ho AC, Schwartz SD. Removal of posterior segment retained lens material using the OZil phacoemulsification handpiece versus Fragmatome during pars plana vitrectomy. Retina. 2012 Nov-Dec; 32(10):2119-26. PMID: 22718151.
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    48. Witkin AJ, Fineman M, Ho AC, Spirn M. A novel method of draining intraoperative choroidal detachments during 23-gauge pars plana vitrectomy. Arch Ophthalmol. 2012 Aug; 130(8):1048-50. PMID: 22893075.
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    49. Shah CP, Hsu J, Spirn MJ, Donoso L, Garg SJ. Topical aqueous suppression does not significantly affect duration of intraocular gas tamponade after vitrectomy. Retina. 2012 Jan; 32(1):168-71. PMID: 21878847.
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    50. Rezeq SS, Vander JF, Hsu J, Regillo CD, Ho AC, Garg SJ, Spirn MJ. Iatrogrenic retinal breaks. Ophthalmology. 2011 Aug; 118(8):1696, 1696.e1; author reply 1697. PMID: 21813104.
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    51. Baker PS, Spirn MJ, Chiang A, Regillo CD, Ho AC, Vander JF, Kaiser RS. 23-Gauge transconjunctival pars plana vitrectomy for removal of retained lens fragments. Am J Ophthalmol. 2011 Oct; 152(4):624-7. PMID: 21726843.
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    52. Rabinowitz M, Khator P, Shah CP, Ichhpujani P, Spirn MJ, Moster MR. Direct cyclopexy with a posterior infusion cannula. Ophthalmic Surg Lasers Imaging. 2011 Mar-Apr; 42(2):175-6. PMID: 21410110.
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    53. Roe RH, Boyer DS, Spirn MJ, Bakri SJ. Diagnostic and therapeutic challenges. Retina. 2010 Jul-Aug; 30(7):1155-8. PMID: 20616690.
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    54. Ehlers JP, Spirn MJ, Shah CP, Fenton GL, Baker PS, Regillo CD, Ho AC. Ranibizumab for exudative age-related macular degeneration in eyes previously treated with alternative vascular endothelial growth factor inhibitors. Ophthalmic Surg Lasers Imaging. 2010 Mar-Apr; 41(2):182-9. PMID: 20307035.
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    55. Spirn MJ. Comparison of 25, 23 and 20-gauge vitrectomy. Curr Opin Ophthalmol. 2009 May; 20(3):195-9. PMID: 19390437.
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    56. Baker PS, Ho AC, Spirn MJ. Optical coherence tomography of west african crystalline maculopathy. Retin Cases Brief Rep. 2009; 3(1):31-2. PMID: 25390833.
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    57. Ehlers JP, Spirn MJ, Lam A, Sivalingam A, Samuel MA, Tasman W. Combination intravitreal bevacizumab/panretinal photocoagulation versus panretinal photocoagulation alone in the treatment of neovascular glaucoma. Retina. 2008 May; 28(5):696-702. PMID: 18463512.
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    58. Shah CP, McKey J, Spirn MJ, Maguire J. Ocular candidiasis: a review. Br J Ophthalmol. 2008 Apr; 92(4):466-8. PMID: 18369061.
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    59. Lam A, Garg SJ, Spirn MJ, Fineman MS, Sivalingam A. Sterile endophthalmitis following intravitreal injection of preservative-free triamcinolone acetonide. Retin Cases Brief Rep. 2008; 2(3):228-30. PMID: 25390094.
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    60. Spirn MJ, Hubbard GB, Bergstrom C, Harris L, Aaron MM, Broocker G. Ophthalmomyiasis associated with Fuchs heterochromic iridocyclitis. Retina. 2006 Oct; 26(8):973-4. PMID: 17031305.
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    61. Spirn MJ, Lynn MJ, Hubbard GB. Vitreous hemorrhage in children. Ophthalmology. 2006 May; 113(5):848-52. PMID: 16650682.
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    62. Spirn MJ, Dawson DG, Rubinfeld RS, Burris C, Talamo J, Edelhauser HF, Grossniklaus HE. Histopathological analysis of post-laser-assisted in situ keratomileusis corneal ectasia with intrastromal corneal ring segments. Arch Ophthalmol. 2005 Nov; 123(11):1604-7. PMID: 16286627.
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    63. Spirn MJ, Biousse V. Retinal fat emboli. J Emerg Med. 2005 Oct; 29(3):339-40. PMID: 16183457.
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    64. Spaide RF, Spirn MJ. Saccular aneurysms in a case of choroidal melanoma. Retina. 2003 Oct; 23(5):726-8. PMID: 14574270.
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    65. Roth DB, Chieh J, Spirn MJ, Green SN, Yarian DL, Chaudhry NA. Noninfectious endophthalmitis associated with intravitreal triamcinolone injection. Arch Ophthalmol. 2003 Sep; 121(9):1279-82. PMID: 12963610.
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    66. Spirn MJ, Warren FA, Guyer DR, Klancnik JM, Spaide RF. Optical coherence tomography findings in nicotinic acid maculopathy. Am J Ophthalmol. 2003 Jun; 135(6):913-4. PMID: 12788145.
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    67. Spirn MJ, Roth DB, Yarian DL, Green SN. Postoperative fungal endophthalmitis caused by Trichosporon beigelii resistant to amphotericin B. Retina. 2003 Jun; 23(3):404-5. PMID: 12824845.
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    68. Spivey MJ, Spirn MJ. Selective visual attention modulates the direct tilt aftereffect. Percept Psychophys. 2000 Nov; 62(8):1525-33. PMID: 11140176.
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