Thomas Jefferson University

Nasser Semmo

TitleAcademic Specialist
InstitutionThomas Jefferson University
DepartmentResearch Services
Address132 S. 10th St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Manuel O, Laager M, Hirzel C, Neofytos D, Walti LN, Hoenger G, Binet I, Schnyder A, Stampf S, Koller M, Mombelli M, Kim MJ, Hoffmann M, Koenig K, Hess C, Burgener AV, Cipp? PE, H?bel K, Mueller TF, Sidler D, Dahdal S, Suter-Riniker F, Villard J, Zbinden A, Pantaleo G, Semmo N, Hadaya K, Enr?quez N, Meylan PR, Froissart M, Golshayan D, Fehr T, Huynh-Do U, Pascual M, Van Delden C, Hirsch HH, J?ni P, Mueller NJ. Immune monitoring-guided vs fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients. A Multicenter, Randomized Clinical Trial. Clin Infect Dis. 2023 Sep 22. PMID: 37738676.
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    2. Terziroli Beretta-Piccoli B, Buescher G, Dalekos G, Zachou K, Geerts A, Semmo N, Kolev M, De Martin E, Janik MK, Madaleno J, Lalosevic Stojkovic M, Dumortier J, Vanwolleghem T, Schregel I, Steinmann S, Lacaille F, Sebode M. Hepatic safety and efficacy of immunomodulatory drugs used in patients with autoimmune hepatitis. J Autoimmun. 2023 Sep 14; 140:103113. PMID: 37716078.
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    3. Kolev M, Sarbu AC, M?ller B, Maurer B, Kollert F, Semmo N. Belimumab treatment in autoimmune hepatitis and primary biliary cholangitis - a case series. J Transl Autoimmun. 2023; 6:100189. PMID: 36718275.
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    4. Beyoglu D, Schwalm S, Semmo N, Huwiler A, Idle JR. Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. Int J Mol Sci. 2023 01 11; 24(2). PMID: 36674922.
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    5. Kolev M, Diem S, Diem L, Rodrigues SG, Berzigotti A, Stirnimann G, Semmo N. Mycophenolate mofetil as second line treatment in autoimmune hepatitis - A retrospective single center analysis. J Transl Autoimmun. 2022; 5:100172. PMID: 36451933.
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    6. Codoni G, Kirchner T, Engel B, Villamil AM, Efe C, St?ttermayer AF, Weltzsch JP, Sebode M, Bernsmeier C, Lleo A, Gevers TJ, Kupcinskas L, Castiella A, Pinazo J, De Martin E, Bobis I, Sandahl TD, Pedica F, Invernizzi F, Del Poggio P, Bruns T, Kolev M, Semmo N, Bessone F, Giguet B, Poggi G, Ueno M, Jang H, Elpek G?, Soylu NK, Cerny A, Wedemeyer H, Vergani D, Mieli-Vergani G, Lucena MI, Andrade RJ, Zen Y, Taubert R, Terziroli Beretta-Piccoli B. Histological and serological features of acute liver injury after SARS-CoV-2 vaccination. JHEP Rep. 2023 Jan; 5(1):100605. PMID: 36440259.
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    7. Kolev M, Horn MP, Semmo N, Nagler M. Rational development and application of biomarkers in the field of autoimmunity: A conceptual framework guiding clinicians and researchers. J Transl Autoimmun. 2022; 5:100151. PMID: 35309737.
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    8. Bihl F, Bruggmann P, Castro Bat?njer E, Dufour JF, Lavanchy D, M?llhaupt B, Negro F, Razavi H, Scheidegger C, Semela D, Semmo N, Blach S. HCV disease burden and population segments in Switzerland. Liver Int. 2022 02; 42(2):330-339. PMID: 34839578.
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    9. Aghemo A, Horsmans Y, Bourgeois S, Bondin M, Gschwantler M, Hofer H, Semmo N, Negro F, Zhang Z, Marcinak J, Veitsman E, Hazzan R, Mimidis K, Goulis I, Marques N, Flisiak R, Mazur W, Roncero C, Marra F, Pageaux GP, Asselah T, Lampertico P. Correction to: Real-World Outcomes in Historically Underserved Patients with Chronic Hepatitis C Infection Treated with Glecaprevir/Pibrentasvir. Infect Dis Ther. 2021 Dec; 10(4):2223-2225. PMID: 34529256.
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    10. Diem S, Gottstein B, Beldi G, Semmo N, Diem LF. Accelerated Course of Alveolar Echinococcosis After Treatment With Steroids in a Patient With Autoimmune Encephalitis. Cureus. 2021 Oct; 13(10):e18831. PMID: 34820209.
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    11. Yilmaz B, Ruckstuhl L, M?llhaupt B, Magenta L, Kuster MH, Clerc O, Torgler R, Semmo N. Pilot Sub-Study of the Effect of Hepatitis C Cure by Glecaprevir/Pibrentasvir on the Gut Microbiome of Patients with Chronic Hepatitis C Genotypes 1 to 6 in the Mythen Study. Pharmaceuticals (Basel). 2021 Sep 16; 14(9). PMID: 34577631.
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    12. Vuille-Lessard ?, Montani M, Bosch J, Semmo N. Autoimmune hepatitis triggered by SARS-CoV-2 vaccination. J Autoimmun. 2021 09; 123:102710. PMID: 34332438.
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    13. Aghemo A, Horsmans Y, Bourgeois S, Bondin M, Gschwantler M, Hofer H, Semmo N, Negro F, Zhang Z, Marcinak J, Veitsman E, Hazzan R, Mimidis K, Goulis I, Marques N, Flisiak R, Mazur W, Roncero C, Marra F, Pageaux GP, Asselah T, Lampertico P. Real-World Outcomes in Historically Underserved Patients with Chronic Hepatitis?C Infection Treated with Glecaprevir/Pibrentasvir. Infect Dis Ther. 2021 Dec; 10(4):2203-2222. PMID: 34125405.
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    14. M?llhaupt B, Semela D, Ruckstuhl L, Magenta L, Clerc O, Torgler R, Negro F, Semmo N. Real-world effectiveness and safety of glecaprevir/pibrentasvir therapy in patients with chronic hepatitis C virus infection in Switzerland. Swiss Med Wkly. 2021 01 18; 151:w20399. PMID: 33516161.
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    15. Moullet B, Kolev M, Ebner L, Langer R, Gr?ni C, Obmann V, Maurer M, Semmo N, Christe A, Huber AT. Adult form of Langerhans cell histiocytosis with pulmonary and hepatic involvement mimicking malignancy in a patient with chronic hepatitis C infection. Radiol Case Rep. 2021 Feb; 16(2):327-333. PMID: 33318775.
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    16. Semmo N, M?llhaupt B, Ruckstuhl L, Magenta L, Clerc O, Torgler R, Semela D. A prospective, multicenter, post-marketing observational study to measure the quality of life of HCV genotype 1 infected, treatment na?ve patients suffering from fatigue and receiving 3D regimen: The HEMATITE study. PLoS One. 2020; 15(11):e0241267. PMID: 33147283.
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    17. Roelens M, Bertisch B, Moradpour D, Cerny A, Semmo N, Schmid P, M?llhaupt B, Clerc O, Semela D, Junker C, Negro F, Keiser O. All-Cause Mortality and Causes of Death in the Swiss Hepatitis C Cohort Study (SCCS). Open Forum Infect Dis. 2020 Aug; 7(8):ofaa308. PMID: 32855989.
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    18. Piccinni R, Rodrigues SG, Montani M, Murgia G, Delgado MG, Casu S, Stirnimann G, Semmo N, De Gottardi A, Dufour JF, Berzigotti A. Controlled attenuation parameter reflects steatosis in compensated advanced chronic liver disease. Liver Int. 2020 05; 40(5):1151-1158. PMID: 31823449.
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    19. About F, Bibert S, Jouanguy E, Nalpas B, Lorenzo L, Rattina V, Zarhrate M, Hanein S, Munteanu M, M?llhaupt B, Semela D, Semmo N, Casanova JL, Theodorou I, Sultanik P, Poynard T, Pol S, Bochud PY, Cobat A, Abel L. Identification of an Endoglin Variant Associated With HCV-Related Liver Fibrosis Progression by Next-Generation Sequencing. Front Genet. 2019; 10:1024. PMID: 31749832.
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    20. Riebensahm C, Ka D, Sow A, Semmo N, Wandeler G. A closer look at the spectrum of drug-induced liver injury in sub-Saharan Africa. Expert Rev Clin Pharmacol. 2019 Sep; 12(9):875-883. PMID: 31269818.
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    21. Brezzi M, Bertisch B, Roelens M, Moradpour D, Terziroli Beretta-Piccoli B, Semmo N, M?llhaupt B, Semela D, Negro F, Keiser O. Impact of geographic origin on access to therapy and therapy outcomes in the Swiss Hepatitis C Cohort Study. PLoS One. 2019; 14(6):e0218706. PMID: 31233524.
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    22. Terziroli Beretta-Piccoli B, Di Bartolomeo C, Deleonardi G, Grondona AG, Silvestri T, Tesei C, Melidona L, Cerny A, Mertens J, Semmo N, Semela D, Moradpour D, Mieli-Vergani G, Vergani D, Muratori L. Autoimmune liver serology before and after successful treatment of chronic hepatitis C by direct acting antiviral agents. J Autoimmun. 2019 08; 102:89-95. PMID: 31047768.
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    23. Asgari S, Chaturvedi N, Scepanovic P, Hammer C, Semmo N, Giostra E, M?llhaupt B, Angus P, Thompson AJ, Moradpour D, Fellay J. Human genomics of acute liver failure due to hepatitis B virus infection: An exome sequencing study in liver transplant recipients. J Viral Hepat. 2019 02; 26(2):271-277. PMID: 30315682.
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    24. Margini C, Murgia G, Stirnimann G, De Gottardi A, Semmo N, Casu S, Bosch J, Dufour JF, Berzigotti A. Prognostic Significance of Controlled Attenuation Parameter in Patients With Compensated Advanced Chronic Liver Disease. Hepatol Commun. 2018 Aug; 2(8):929-940. PMID: 30094404.
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    25. Weiss L, Wustmann K, Semmo M, Schwerzmann M, Semmo N. Elbasvir/Grazoprevir, an Alternative in Antiviral Hepatitis C Therapy in Patients under Amiodarone Treatment. Case Rep Gastroenterol. 2018 Jan-Apr; 12(1):92-98. PMID: 29606942.
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    26. Simillion C, Semmo N, Idle JR, Beyoglu D. Robust Regression Analysis of GCMS Data Reveals Differential Rewiring of Metabolic Networks in Hepatitis B and C Patients. Metabolites. 2017 Oct 08; 7(4). PMID: 28991180.
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    27. Patsenker E, Chicca A, Petrucci V, Moghadamrad S, de Gottardi A, Hampe J, Gertsch J, Semmo N, Stickel F. 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice. J Mol Med (Berl). 2017 10; 95(10):1077-1089. PMID: 28689299.
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    28. Simonetta F, Pradier A, Masouridi-Levrat S, van Delden C, Giostra E, Morard I, Mueller N, Muellhaupt B, Valli PV, Semmo N, Seebach J, Chalandon Y, Kaiser L, Roosnek E. Torque Teno Virus Load and Acute Rejection After Orthotopic Liver Transplantation. Transplantation. 2017 07; 101(7):e219-e221. PMID: 28263221.
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    29. Gauthiez E, Habfast-Robertson I, R?eger S, Kutalik Z, Aubert V, Berg T, Cerny A, Gorgievski M, George J, Heim MH, Malinverni R, Moradpour D, M?llhaupt B, Negro F, Semela D, Semmo N, Villard J, Bibert S, Bochud PY. A systematic review and meta-analysis of HCV clearance. Liver Int. 2017 10; 37(10):1431-1445. PMID: 28261910.
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    30. Wang Q, Klenerman P, Semmo N. Significance of anti-HBc alone serological status in clinical practice. Lancet Gastroenterol Hepatol. 2017 02; 2(2):123-134. PMID: 28403982.
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    31. Hirzel C, Wandeler G, Owczarek M, Gorgievski-Hrisoho M, Dufour JF, Semmo N, Z?rcher S. Molecular epidemiology of hepatitis B virus infection in Switzerland: a retrospective cohort study. BMC Infect Dis. 2015 Oct 30; 15:483. PMID: 26518625.
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    32. Buch S, Stickel F, Tr?po E, Way M, Herrmann A, Nischalke HD, Brosch M, Rosendahl J, Berg T, Ridinger M, Rietschel M, McQuillin A, Frank J, Kiefer F, Schreiber S, Lieb W, Soyka M, Semmo N, Aigner E, Datz C, Schmelz R, Br?ckner S, Zeissig S, Stephan AM, Wodarz N, Devi?re J, Clumeck N, Sarrazin C, Lammert F, Gustot T, Deltenre P, V?lzke H, Lerch MM, Mayerle J, Eyer F, Schafmayer C, Cichon S, N?then MM, Nothnagel M, Ellinghaus D, Huse K, Franke A, Zopf S, Hellerbrand C, Moreno C, Franchimont D, Morgan MY, Hampe J. A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis. Nat Genet. 2015 Dec; 47(12):1443-8. PMID: 26482880.
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    33. Terczynska-Dyla E, Bibert S, Duong FHT, Krol I, J?rgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, M?llhaupt B, Negro F, Santoro R, Semela D, Semmo N, Heim MH, Bochud PY, Hartmann R. Corrigendum: reduced IFN?4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nat Commun. 2015 Jun 29; 6:7280. PMID: 26118470.
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    34. Patsenker E, Sachse P, Chicca A, Gachet MS, Schneider V, Mattsson J, Lanz C, Worni M, de Gottardi A, Semmo M, Hampe J, Schafmayer C, Brenneisen R, Gertsch J, Stickel F, Semmo N. Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation. Int J Mol Sci. 2015 Mar 27; 16(4):7057-76. PMID: 25826533.
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    35. Lokhande MU, Thimme R, Klenerman P, Semmo N. Methodologies for the Analysis of HCV-Specific CD4(+) T Cells. Front Immunol. 2015; 6:57. PMID: 25767470.
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    36. Terczynska-Dyla E, Bibert S, Duong FH, Krol I, J?rgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, M?llhaupt B, Negro F, Santoro R, Semela D, Semmo N, Heim MH, Bochud PY, Hartmann R. Reduced IFN?4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes. Nat Commun. 2014 Dec 23; 5:5699. PMID: 25534433.
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    37. Gassanov N, Caglayan E, Semmo N, Massenkeil G, Er F. Cirrhotic cardiomyopathy: a cardiologist's perspective. World J Gastroenterol. 2014 Nov 14; 20(42):15492-8. PMID: 25400434.
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    38. Nischalke HD, Lutz P, Kr?mer B, S?hne J, M?ller T, Rosendahl J, Fischer J, Berg T, Hittatiya K, Fischer HP, Soyka M, Semmo N, Nattermann J, Sauerbruch T, Strassburg CP, Stickel F, Spengler U. A common polymorphism in the NCAN gene is associated with hepatocellular carcinoma in alcoholic liver disease. J Hepatol. 2014 Nov; 61(5):1073-9. PMID: 24946282.
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    39. Bibert S, Roger T, Calandra T, Bochud M, Cerny A, Semmo N, Duong FH, Gerlach T, Malinverni R, Moradpour D, Negro F, M?llhaupt B, Bochud PY. IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction. J Exp Med. 2013 Jun 03; 210(6):1109-16. PMID: 23712427.
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    40. Abdulazim A, H?drich M, Montani M, Semmo N. Acute Hepatitis Induced by Lyprinol, the Lipid Extract of the Green-Lipped Mussel (Perna canaliculus), in a Patient with Polyarthrosis. Case Reports Hepatol. 2012; 2012:135146. PMID: 25954550.
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    41. Witkowski M, Spangenberg HC, Neumann-Haefelin C, B?ttner N, Breous E, Kersting N, Drognitz O, Hopt UT, Blum HE, Semmo N, Thimme R. Lack of ex vivo peripheral and intrahepatic a-fetoprotein-specific CD4+ responses in hepatocellular carcinoma. Int J Cancer. 2011 Nov 01; 129(9):2171-82. PMID: 21170957.
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    42. Gassanov N, Semmo N, Semmo M, Nia AM, Fuhr U, Er F. Arginine vasopressin (AVP) and treatment with arginine vasopressin receptor antagonists (vaptans) in congestive heart failure, liver cirrhosis and syndrome of inappropriate antidiuretic hormone secretion (SIADH). Eur J Clin Pharmacol. 2011 Apr; 67(4):333-346. PMID: 21327910.
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    43. Er F, Ederer S, Nia AM, Caglayan E, Dahlem KM, Semmo N, Gassanov N. Accuracy of Doppler-echocardiographic mean pulmonary artery pressure for diagnosis of pulmonary hypertension. PLoS One. 2010 Dec 17; 5(12):e15670. PMID: 21179417.
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    44. Mueller M, Spangenberg HC, Kersting N, Altay T, Blum HE, Klenerman P, Thimme R, Semmo N. Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154. J Hepatol. 2010 Jun; 52(6):800-11. PMID: 20416967.
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    45. Barnes E, Gelderblom HC, Humphreys I, Semmo N, Reesink HW, Beld MG, van Lier RA, Klenerman P. Cellular immune responses during high-dose interferon-alpha induction therapy for hepatitis C virus infection. J Infect Dis. 2009 Mar 15; 199(6):819-28. PMID: 19434929.
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    46. Semmo N, Klenerman P. CD4+ T cell responses in hepatitis C virus infection. World J Gastroenterol. 2007 Sep 28; 13(36):4831-8. PMID: 17828814.
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    47. Lucas M, Ulsenheimer A, Pfafferot K, Heeg MH, Gaudieri S, Gr?ner N, Rauch A, Gerlach JT, Jung MC, Zachoval R, Pape GR, Schraut W, Santantonio T, Nitschko H, Obermeier M, Phillips R, Scriba TJ, Semmo N, Day C, Weber JN, Fidler S, Thimme R, Haberstroh A, Baumert TF, Klenerman P, Diepolder HM. Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection. PLoS One. 2007 Jul 25; 2(7):e649. PMID: 17653276.
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    48. Semmo N, Lucas M, Krashias G, Lauer G, Chapel H, Klenerman P. Maintenance of HCV-specific T-cell responses in antibody-deficient patients a decade after early therapy. Blood. 2006 Jun 01; 107(11):4570-1. PMID: 16717132.
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    49. Semmo N, Day CL, Ward SM, Lucas M, Harcourt G, Loughry A, Klenerman P. Preferential loss of IL-2-secreting CD4+ T helper cells in chronic HCV infection. Hepatology. 2005 May; 41(5):1019-28. PMID: 15841456.
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    50. Semmo N, Barnes E, Taylor C, Kurtz J, Harcourt G, Smith N, Klenerman P. T-cell responses and previous exposure to hepatitis C virus in indeterminate blood donors. Lancet. 2005 Jan 22-28; 365(9456):327-9. PMID: 15664228.
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    51. Lucas M, Vargas-Cuero AL, Lauer GM, Barnes E, Willberg CB, Semmo N, Walker BD, Phillips R, Klenerman P. Pervasive influence of hepatitis C virus on the phenotype of antiviral CD8+ T cells. J Immunol. 2004 Feb 01; 172(3):1744-53. PMID: 14734757.
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