Glenn Rall

Title	Volunteer Faculty
Institution	Thomas Jefferson University
Department	Faculty Records and Publicatio - Thomas Jefferson University
Address	833 Chestnut Street Philadelphia PA 19107
vCard	Download vCard

Research

research activities and funding

R29MH056951 (RALL, GLENN F)Apr 1, 1997 - Mar 31, 2003 NIH REPLICATION AND SPREAD OF NEUROTROPIC VIRUSES Role: Principal Investigator

R01NS040500 (RALL, GLENN F)Apr 1, 2002 - Mar 31, 2008 NIH Pathogenesis of Neurotropic RNA Virus Infections Role: Principal Investigator

R01NS060701 (RALL, GLENN F)Jul 1, 2008 - Jun 30, 2014 NIH Intra- and Inter-Neuronal Viral Trafficking Role: Principal Investigator

R21NS074006 (SCHNELL, MATTHIAS JOHANNES)Jul 1, 2011 - Jun 30, 2015 NIH Fate of neurons following immune-mediated viral clearance Role: Co-Principal Investigator

R03AI094164 (RALL, GLENN F)Mar 1, 2012 - Feb 28, 2015 NIH The Role of Host-Encoded microRNAs in Maintaining Measles Virus Persistence Role: Principal Investigator

R56NS094475 (RALL, GLENN F)Sep 30, 2016 - Sep 29, 2018 NIH Regulation and Relevance of Neuron-Specific Interferon Signaling Pathways Role: Principal Investigator

R21NS099788 (RALL, GLENN F)May 1, 2017 - Apr 30, 2019 NIH RNA Virus Persistence and Reactivation in the Brain Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Shulman RM, Weinberg DS, Ross EA, Ruth K, Rall GF, Olszanski AJ, Helstrom J, Hall MJ, Judd J, Chen DYT, Uzzo RG, Dougherty TP, Williams R, Geynisman DM, Fang CY, Fisher RI, Strother M, Huelsmann E, Adige S, Whooley PD, Zarrabi K, Gupta B, Iyer P, McShane M, Yankey H, Lee CT, Burbure N, Laderman LE, Giurintano J, Reiss S, Horwitz EM. Adverse Events Reported by Patients With Cancer After Administration of a 2-Dose mRNA COVID-19 Vaccine. J Natl Compr Canc Netw. 2022 02; 20(2):160-166. PMID: 35130494.

Citations:
Miller KD, Matullo C, Williams R, Jones CB, Rall GF. Murine BST2/tetherin promotes measles virus infection of neurons. Virology. 2021 11; 563:38-43. PMID: 34416448.

Citations:
Poelaert KCK, Williams RM, Matullo CM, Rall GF. Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes. mBio. 2021 03 23; 12(2). PMID: 33758092.

Citations:
Pearson VR, Bosse JB, Koyuncu OO, Scherer J, Toruno C, Robinson R, Abegglen LM, Schiffman JD, Enquist LW, Rall GF. Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells. PLoS One. 2021; 16(2):e0244334. PMID: 33544724.

Citations:
Balachandran S, Rall GF. Benefits and Perils of Necroptosis in Influenza Virus Infection. J Virol. 2020 04 16; 94(9). PMID: 32051270.

Citations:
Miller KD, Matullo CM, Milora KA, Williams RM, O'Regan KJ, Rall GF. Immune-Mediated Control of a Dormant Neurotropic RNA Virus Infection. J Virol. 2019 09 15; 93(18). PMID: 31270232.

Citations:
Milora KA, Rall GF. Interferon Control of Neurotropic Viral Infections. Trends Immunol. 2019 09; 40(9):842-856. PMID: 31439415.

Citations:
Ingram JP, Thapa RJ, Fisher A, Tummers B, Zhang T, Yin C, Rodriguez DA, Guo H, Lane R, Williams R, Slifker MJ, Basagoudanavar SH, Rall GF, Dillon CP, Green DR, Kaiser WJ, Balachandran S. ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1. J Immunol. 2019 09 01; 203(5):1348-1355. PMID: 31358656.

Citations:
Duong-Ly KC, Kuo YM, Johnson MC, Cote JM, Kollman JM, Soboloff J, Rall GF, Andrews AJ, Peterson JR. T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly. J Cell Sci. 2018 09 05; 131(17). PMID: 30154209.

Citations:
Naaman H, Rabinski T, Yizhak A, Mizrahi S, Avni YS, Taube R, Rager B, Weinstein Y, Rall G, Gopas J, Ofir R. Measles Virus Persistent Infection of Human Induced Pluripotent Stem Cells. Cell Reprogram. 2018 02; 20(1):17-26. PMID: 29412740.

Citations:
Naaman H, Rall G, Matullo C, Veksler-Lublinsky I, Shemer-Avni Y, Gopas J. MiRNA-124 is a link between measles virus persistent infection and cell division of human neuroblastoma cells. PLoS One. 2017; 12(10):e0187077. PMID: 29073265.

Citations:
Miller KD, Rall GF. What Kaplan-Meier survival curves don't tell us about CNS disease. J Neuroimmunol. 2017 07 15; 308:25-29. PMID: 28187911.

Citations:
Miller KD, Schnell MJ, Rall GF. Keeping it in check: chronic viral infection and antiviral immunity in the brain. Nat Rev Neurosci. 2016 12; 17(12):766-776. PMID: 27811921.

Citations:
Solomos AC, O'Regan KJ, Rall GF. CD4+ T cells require either B cells or CD8+ T cells to control spread and pathogenesis of a neurotropic infection. Virology. 2016 12; 499:196-202. PMID: 27677156.

Citations:
Rall G, Knoll LJ. Development of Complex Models to Study Co- and Polymicrobial Infections and Diseases. PLoS Pathog. 2016 Sep; 12(9):e1005858. PMID: 27607188.

Citations:
Solomos AC, Rall GF. Get It through Your Thick Head: Emerging Principles in Neuroimmunology and Neurovirology Redefine Central Nervous System "Immune Privilege". ACS Chem Neurosci. 2016 Apr 20; 7(4):435-41. PMID: 26854733.

Citations:
Rall G. Here I Am, Despite Myself. PLoS Pathog. 2015 Sep; 11(9):e1005106. PMID: 26356415.

Citations:
O'Donnell LA, Henkins KM, Kulkarni A, Matullo CM, Balachandran S, Pattisapu AK, Rall GF. Interferon gamma induces protective non-canonical signaling pathways in primary neurons. J Neurochem. 2015 Oct; 135(2):309-22. PMID: 26190522.

Citations:
Holmgren AM, Miller KD, Cavanaugh SE, Rall GF. Bst2/Tetherin Is Induced in Neurons by Type I Interferon and Viral Infection but Is Dispensable for Protection against Neurotropic Viral Challenge. J Virol. 2015 Nov; 89(21):11011-8. PMID: 26311886.

Citations:
Davis BM, Rall GF, Schnell MJ. Everything You Always Wanted to Know About Rabies Virus (But Were Afraid to Ask). Annu Rev Virol. 2015 Nov; 2(1):451-71. PMID: 26958924.

Citations:
Cavanaugh SE, Holmgren AM, Rall GF. Homeostatic interferon expression in neurons is sufficient for early control of viral infection. J Neuroimmunol. 2015 Feb 15; 279:11-9. PMID: 25669994.

Citations:
Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S. Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):E3109-18. PMID: 23898178.

Citations:
Gomme EA, Wirblich C, Addya S, Rall GF, Schnell MJ. Immune clearance of attenuated rabies virus results in neuronal survival with altered gene expression. PLoS Pathog. 2012; 8(10):e1002971. PMID: 23071441.

Citations:
Podolsky MA, Solomos AC, Durso LC, Evans SM, Rall GF, Rose RW. Extended JAK activation and delayed STAT1 dephosphorylation contribute to the distinct signaling profile of CNS neurons exposed to interferon-gamma. J Neuroimmunol. 2012 Oct 15; 251(1-2):33-8. PMID: 22769061.

Citations:
O'Donnell LA, Conway S, Rose RW, Nicolas E, Slifker M, Balachandran S, Rall GF. STAT1-independent control of a neurotropic measles virus challenge in primary neurons and infected mice. J Immunol. 2012 Feb 15; 188(4):1915-23. PMID: 22246627.

Citations:
Matullo CM, O'Regan KJ, Curtis M, Rall GF. CNS recruitment of CD8+ T lymphocytes specific for a peripheral virus infection triggers neuropathogenesis during polymicrobial challenge. PLoS Pathog. 2011 Dec; 7(12):e1002462. PMID: 22216008.

Citations:
O'Donnell LA, Rall GF. Blue moon neurovirology: the merits of studying rare CNS diseases of viral origin. J Neuroimmune Pharmacol. 2010 Sep; 5(3):443-55. PMID: 20419352.

Citations:
Matullo CM, O'Regan KJ, Hensley H, Curtis M, Rall GF. Lymphocytic choriomeningitis virus-induced mortality in mice is triggered by edema and brain herniation. J Virol. 2010 Jan; 84(1):312-20. PMID: 19828618.

Citations:
Young VA, Rall GF. Making it to the synapse: measles virus spread in and among neurons. Curr Top Microbiol Immunol. 2009; 330:3-30. PMID: 19203102.

Citations:
Rose RW, Vorobyeva AG, Skipworth JD, Nicolas E, Rall GF. Altered levels of STAT1 and STAT3 influence the neuronal response to interferon gamma. J Neuroimmunol. 2007 Dec; 192(1-2):145-56. PMID: 18006082.

Citations:
Makhortova NR, Askovich P, Patterson CE, Gechman LA, Gerard NP, Rall GF. Neurokinin-1 enables measles virus trans-synaptic spread in neurons. Virology. 2007 May 25; 362(1):235-44. PMID: 17434199.

Citations:
Makhortova NR, Rall GF, Prasolov VS. [Receptor-independent spread of measles virus is unique to neurons, and involves fusion of synaptic membranes]. Mol Biol (Mosk). 2007 Jan-Feb; 41(1):186-8. PMID: 17380905.

Citations:
Gussow AM, Giordani NV, Tran RK, Imai Y, Kwiatkowski DL, Rall GF, Margolis TP, Bloom DC. Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic mice. J Virol. 2006 Oct; 80(19):9414-23. PMID: 16973547.

Citations:
Daley JK, Gechman LA, Skipworth J, Rall GF. Poliovirus replication and spread in primary neuron cultures. Virology. 2005 Sep 15; 340(1):10-20. PMID: 16009390.

Citations:
Greger JG, Katz RA, Taganov K, Rall GF, Skalka AM. Transduction of terminally differentiated neurons by avian sarcoma virus. J Virol. 2004 May; 78(9):4902-6. PMID: 15078971.

Citations:
Patterson CE, Daley JK, Echols LA, Lane TE, Rall GF. Measles virus infection induces chemokine synthesis by neurons. J Immunol. 2003 Sep 15; 171(6):3102-9. PMID: 12960336.

Citations:
Rall GF. Measles virus 1998-2002: progress and controversy. Annu Rev Microbiol. 2003; 57:343-67. PMID: 14527283.

Citations:
Patterson CE, Daley JK, Rall GF. Neuronal survival strategies in the face of RNA viral infection. J Infect Dis. 2002 Dec 01; 186 Suppl 2:S215-9. PMID: 12424700.

Citations:
Phillips JJ, Chua MM, Rall GF, Weiss SR. Murine coronavirus spike glycoprotein mediates degree of viral spread, inflammation, and virus-induced immunopathology in the central nervous system. Virology. 2002 Sep 15; 301(1):109-20. PMID: 12359451.

Citations:
Katz RA, Greger JG, Darby K, Boimel P, Rall GF, Skalka AM. Transduction of interphase cells by avian sarcoma virus. J Virol. 2002 Jun; 76(11):5422-34. PMID: 11991971.

Citations:
Patterson CE, Lawrence DM, Echols LA, Rall GF. Immune-mediated protection from measles virus-induced central nervous system disease is noncytolytic and gamma interferon dependent. J Virol. 2002 May; 76(9):4497-506. PMID: 11932415.

Citations:
Evans CF, Redwine JM, Patterson CE, Askovic S, Rall GF. LCMV and the central nervous system: uncovering basic principles of CNS physiology and virus-induced disease. Curr Top Microbiol Immunol. 2002; 263:177-95. PMID: 11987814.

Citations:
Manchester M, Rall GF. Model Systems: transgenic mouse models for measles pathogenesis. Trends Microbiol. 2001 Jan; 9(1):19-23. PMID: 11166238.

Citations:
Rall GF, Lawrence DM, Patterson CE. The application of transgenic and knockout mouse technology for the study of viral pathogenesis. Virology. 2000 Jun 05; 271(2):220-6. PMID: 10860874.

Citations:
Kappes DJ, Lawrence DM, Vaughn MM, Dav? VP, Belman AR, Rall GF. Protection of CD3 delta knockout mice from lymphocytic choriomeningitis virus-induced immunopathology: implications for viral neuroinvasion. Virology. 2000 Apr 10; 269(2):248-56. PMID: 10753703.

Citations:
Lawrence DM, Patterson CE, Gales TL, D'Orazio JL, Vaughn MM, Rall GF. Measles virus spread between neurons requires cell contact but not CD46 expression, syncytium formation, or extracellular virus production. J Virol. 2000 Feb; 74(4):1908-18. PMID: 10644364.

Citations:
Lawrence DM, Vaughn MM, Belman AR, Cole JS, Rall GF. Immune response-mediated protection of adult but not neonatal mice from neuron-restricted measles virus infection and central nervous system disease. J Virol. 1999 Mar; 73(3):1795-801. PMID: 9971756.

Citations:
Pugh JC, Guo JT, Aldrich C, Rall G, Kajino K, Tennant B, England JM, Mason WS. Aberrant expression of a cytokeratin in a subset of hepatocytes during chronic WHV infection. Virology. 1998 Sep 15; 249(1):68-79. PMID: 9740778.

Citations:
Rall GF. CNS neurons: the basis and benefits of low class I major histocompatibility complex expression. Curr Top Microbiol Immunol. 1998; 232:115-34. PMID: 9557396.

Citations:
Brot MD, Rall GF, Oldstone MB, Koob GF, Gold LH. Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice. J Neurovirol. 1997 Aug; 3(4):265-73. PMID: 9291234.

Citations:
Rall GF, Manchester M, Daniels LR, Callahan EM, Belman AR, Oldstone MB. A transgenic mouse model for measles virus infection of the brain. Proc Natl Acad Sci U S A. 1997 Apr 29; 94(9):4659-63. PMID: 9114047.

Citations:
Rall GF, Mucke L, Oldstone MB. Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo. J Exp Med. 1995 Nov 01; 182(5):1201-12. PMID: 7595191.

Citations:
Race RE, Priola SA, Bessen RA, Ernst D, Dockter J, Rall GF, Mucke L, Chesebro B, Oldstone MB. Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent. Neuron. 1995 Nov; 15(5):1183-91. PMID: 7576660.

Citations:
Tishon A, Lewicki H, Rall G, Von Herrath M, Oldstone MB. An essential role for type 1 interferon-gamma in terminating persistent viral infection. Virology. 1995 Sep 10; 212(1):244-50. PMID: 7676639.

Citations:
Rall GF, Oldstone MB. Virus-neuron-cytotoxic T lymphocyte interactions. Curr Top Microbiol Immunol. 1995; 202:261-73. PMID: 7587367.

Citations:
Rall GF, Mucke L, Nerenberg M, Oldstone MB. A transgenic mouse model to assess the interaction of cytotoxic T lymphocytes with virally infected, class I MHC-expressing astrocytes. J Neuroimmunol. 1994 Jun; 52(1):61-8. PMID: 8207120.

Citations:
Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L. Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature. 1994 Jan 13; 367(6459):188-93. PMID: 8114918.

Citations:
Evans CF, Rall GF, Killeen N, Littman D, Oldstone MB. CD2-deficient mice generate virus-specific cytotoxic T lymphocytes upon infection with lymphocytic choriomeningitis virus. J Immunol. 1993 Dec 01; 151(11):6259-64. PMID: 7902375.

Citations:
de la Torre JC, Rall G, Oldstone C, Sanna PP, Borrow P, Oldstone MB. Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons. J Virol. 1993 Dec; 67(12):7350-9. PMID: 8230458.

Citations:
Oldstone MB, Rall GF. Mechanism and consequence of viral persistence in cells of the immune system and neurons. Intervirology. 1993; 35(1-4):116-21. PMID: 8407238.

Citations:
Rall GF, Kupershmidt S, Sugg N, Veach RA, Ben-Porat T. Functions of the sequences at the ends of the inverted repeats of pseudorabies virus. J Virol. 1992 Mar; 66(3):1506-19. PMID: 1310762.

Citations:
Kupershmidt S, Rall GF, Lu ZQ, Ben-Porat T. Cleavage of concatemeric DNA at the internal junction of "translocation" mutants of pseudorabies virus and inversion of their L component appear to be linked. Virology. 1992 Mar; 187(1):223-32. PMID: 1310557.

Citations:
Rall GF, Lu ZQ, Sugg N, Veach RA, Ben-Porat T. Acquisition of an additional internal cleavage site differentially affects the ability of pseudorabies virus to multiply in different host cells. J Virol. 1991 Dec; 65(12):6604-11. PMID: 1658364.

Citations:
Rall GF, Kupershmidt S, Lu XQ, Mettenleiter TC, Ben-Porat T. Low-level inversion of the L component of pseudorabies virus is not dependent on sequence homology. J Virol. 1991 Dec; 65(12):7016-9. PMID: 1658393.

Citations:
Reilly LM, Rall G, Lomniczi B, Mettenleiter TC, Kuperschmidt S, Ben-Porat T. The ability of pseudorabies virus to grow in different hosts is affected by the duplication and translocation of sequences from the left end of the genome to the UL-US junction. J Virol. 1991 Nov; 65(11):5839-47. PMID: 1656073.

Citations:
DeMarchi JM, Lu ZQ, Rall G, Kupershmidt S, Ben-Porat T. Structural organization of the termini of the L and S components of the genome of pseudorabies virus. J Virol. 1990 Oct; 64(10):4968-77. PMID: 2168980.

Citations:
Lu ZQ, DeMarchi JM, Harper L, Rall GF, Ben-Porat T. Nucleotide sequences at recombinational junctions present in pseudorabies virus variants with an invertible L component. J Virol. 1989 Jun; 63(6):2690-8. PMID: 2542582.

Citations:

Year	Publications
1997	2
1998	2
1999	1
2000	3
2001	1
2002	5
2003	2
2004	1
2005	1
2006	1
2007	3
2009	1
2010	2
2011	1
2012	3
2013	1
2014	1
2015	4
2016	4
2017	2
2018	2
2019	3
2020	1
2021	3
2022	1

Rall's Networks

Click the

Explore

buttons for more information and interactive visualizations!

Concepts (327)

Explore

Co-Authors (3)

Explore

Similar People (60)

Explore

Same Department

Explore

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement