Thomas Jefferson University

Satoshi Kubota

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address1025 Walnut Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fujita H, Habuta M, Hattori T, Kubota S, Kumon H, Ohuchi H. UCP1 expression in the mouse adrenal gland is not upregulated by thermogenic conditions. Biochem Biophys Res Commun. 2021 08 20; 566:184-189. PMID: 34129966.
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    2. Elseoudi A, Nishida T, Mizukawa T, Hattori T, Kawata K, Taha EA, Takigawa M, Kubota S. Bipartite regulation of cellular communication network factor 2 and fibroblast growth factor 1 genes by fibroblast growth factor 1 through histone deacetylase 1 and fork head box protein A1. J Cell Commun Signal. 2021 Mar; 15(1):81-91. PMID: 33398720.
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    3. Hoshijima M, Hattori T, Aoyama E, Nishida T, Kubota S, Kamioka H, Takigawa M. Roles of Interaction between CCN2 and Rab14 in Aggrecan Production by Chondrocytes. Int J Mol Sci. 2020 Apr 16; 21(8). PMID: 32316324.
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    4. Kubota S, Tanaka M, Endo H, Ito Y, Onuma K, Ueda Y, Kamiura S, Yoshino K, Kimura T, Kondo J, Inoue M. Dedifferentiation of neuroendocrine carcinoma of the uterine cervix in hypoxia. Biochem Biophys Res Commun. 2020 04 02; 524(2):398-404. PMID: 32007268.
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    5. Kubota S, Takigawa M. Preparation of Module-Specific Antibodies Against CCN Family Members. Methods Mol Biol. 2017; 1489:115-126. PMID: 27734371.
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    6. Nishida T, Kubota S, Takigawa M. Production of Recombinant CCN2 Protein by Mammalian Cells. Methods Mol Biol. 2017; 1489:95-105. PMID: 27734369.
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    7. Eguchi T, Calderwood SK, Takigawa M, Kubota S, Kozaki KI. Intracellular MMP3 Promotes HSP Gene Expression in Collaboration With Chromobox Proteins. J Cell Biochem. 2017 01; 118(1):43-51. PMID: 27206651.
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    8. Murase Y, Hattori T, Aoyama E, Nishida T, Maeda-Uematsu A, Kawaki H, Lyons KM, Sasaki A, Takigawa M, Kubota S. Role of CCN2 in Amino Acid Metabolism of Chondrocytes. J Cell Biochem. 2016 Apr; 117(4):927-37. PMID: 26364758.
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    9. Miyake Y, Furumatsu T, Kubota S, Kawata K, Ozaki T, Takigawa M. Mechanical stretch increases CCN2/CTGF expression in anterior cruciate ligament-derived cells. Biochem Biophys Res Commun. 2011 Jun 03; 409(2):247-52. PMID: 21569762.
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    10. Kondo S, Kubota S, Mukudai Y, Nishida T, Yoshihama Y, Shirota T, Shintani S, Takigawa M. Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA. Biochem Biophys Res Commun. 2011 Feb 18; 405(3):382-7. PMID: 21236242.
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    11. Sumiyoshi K, Kubota S, Ohgawara T, Kawata K, Nishida T, Shimo T, Yamashiro T, Takigawa M. Identification of miR-1 as a micro RNA that supports late-stage differentiation of growth cartilage cells. Biochem Biophys Res Commun. 2010 Nov 12; 402(2):286-90. PMID: 20937250.
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    12. Sumiyoshi K, Kubota S, Furuta RA, Yasui K, Aoyama E, Kawaki H, Kawata K, Ohgawara T, Yamashiro T, Takigawa M. Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2. J Cell Commun Signal. 2010 Mar; 4(1):5-14. PMID: 19798594.
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    13. Aoyama E, Hattori T, Hoshijima M, Araki D, Nishida T, Kubota S, Takigawa M. N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan. Biochem J. 2009 May 27; 420(3):413-20. PMID: 19298220.
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    14. Nishida T, Kondo S, Maeda A, Kubota S, Lyons KM, Takigawa M. CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition. Bone. 2009 Jan; 44(1):24-31. PMID: 18835464.
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    15. Kuroda C, Kubota S, Kawata K, Aoyama E, Sumiyoshi K, Oka M, Inoue M, Minagi S, Takigawa M. Distribution, gene expression, and functional role of EphA4 during ossification. Biochem Biophys Res Commun. 2008 Sep 12; 374(1):22-7. PMID: 18601903.
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    16. Eguchi T, Kubota S, Kawata K, Mukudai Y, Uehara J, Ohgawara T, Ibaragi S, Sasaki A, Kuboki T, Takigawa M. Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene. Mol Cell Biol. 2008 Apr; 28(7):2391-413. PMID: 18172013.
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    17. Kawaki H, Kubota S, Suzuki A, Yamada T, Matsumura T, Mandai T, Yao M, Maeda T, Lyons KM, Takigawa M. Functional requirement of CCN2 for intramembranous bone formation in embryonic mice. Biochem Biophys Res Commun. 2008 Feb 08; 366(2):450-6. PMID: 18067859.
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    18. Matsumoto Y, Motoki T, Kubota S, Takigawa M, Tsubouchi H, Gohda E. Inhibition of tumor-stromal interaction through HGF/Met signaling by valproic acid. Biochem Biophys Res Commun. 2008 Feb 01; 366(1):110-6. PMID: 18053801.
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    19. Yanagita T, Kubota S, Kawaki H, Kawata K, Kondo S, Takano-Yamamoto T, Tanaka S, Takigawa M. Expression and physiological role of CCN4/Wnt-induced secreted protein 1 mRNA splicing variants in chondrocytes. FEBS J. 2007 Apr; 274(7):1655-65. PMID: 17381509.
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    20. Ono M, Kubota S, Fujisawa T, Sonoyama W, Kawaki H, Akiyama K, Oshima M, Nishida T, Yoshida Y, Suzuki K, Takigawa M, Kuboki T. Promotion of attachment of human bone marrow stromal cells by CCN2. Biochem Biophys Res Commun. 2007 May 25; 357(1):20-5. PMID: 17399683.
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    21. Eguchi T, Kubota S, Kawata K, Mukudai Y, Ohgawara T, Miyazono K, Nakao K, Kondo S, Takigawa M. Different transcriptional strategies for ccn2/ctgf gene induction between human chondrocytic and breast cancer cell lines. Biochimie. 2007 Mar; 89(3):278-88. PMID: 17291666.
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    22. Kawata K, Eguchi T, Kubota S, Kawaki H, Oka M, Minagi S, Takigawa M. Possible role of LRP1, a CCN2 receptor, in chondrocytes. Biochem Biophys Res Commun. 2006 Jun 30; 345(2):552-9. PMID: 16690029.
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    23. Kubota S, Mukudai Y, Moritani NH, Nakao K, Kawata K, Takigawa M. Translational repression by the cis-acting element of structure-anchored repression (CAESAR) of human ctgf/ccn2 mRNA. FEBS Lett. 2005 Jul 04; 579(17):3751-8. PMID: 16044512.
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    24. Nakao K, Kubota S, Doi H, Eguchi T, Oka M, Fujisawa T, Nishida T, Takigawa M. Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism. Bone. 2005 May; 36(5):884-92. PMID: 15820145.
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    25. Fang J, Kubota S, Yang B, Zhou N, Zhang H, Godbout R, Pomerantz RJ. A DEAD box protein facilitates HIV-1 replication as a cellular co-factor of Rev. Virology. 2004 Dec 20; 330(2):471-80. PMID: 15567440.
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    26. Mukudai Y, Kubota S, Eguchi T, Kondo S, Nakao K, Takigawa M. Regulation of chicken ccn2 gene by interaction between RNA cis-element and putative trans-factor during differentiation of chondrocytes. J Biol Chem. 2005 Feb 04; 280(5):3166-77. PMID: 15550387.
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    27. Minato M, Kubota S, Kawaki H, Nishida T, Miyauchi A, Hanagata H, Nakanishi T, Takano-Yamamoto T, Takigawa M. Module-specific antibodies against human connective tissue growth factor: utility for structural and functional analysis of the factor as related to chondrocytes. J Biochem. 2004 Mar; 135(3):347-54. PMID: 15113833.
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    28. Kawaki H, Kubota S, Minato M, Moritani NH, Hattori T, Hanagata H, Kubota M, Miyauchi A, Nakanishi T, Takigawa M. Novel enzyme-linked immunosorbent assay systems for the quantitative analysis of connective tissue growth factor (CTGF/Hcs24/CCN2): detection of HTLV-I tax-induced CTGF from a human carcinoma cell line. DNA Cell Biol. 2003 Oct; 22(10):641-8. PMID: 14611685.
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    29. Mukudai Y, Kubota S, Takigawa M. Conserved repressive regulation of connective tissue growth factor/hypertrophic chondrocyte-specific gene 24 (ctgf/hcs24) enabled by different elements and factors among vertebrate species. Biol Chem. 2003 Jan; 384(1):1-9. PMID: 12674494.
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    30. Yosimichi G, Kubota S, Hattori T, Nishida T, Nawachi K, Nakanishi T, Kamada M, Takano-Yamamoto T, Takigawa M. CTGF/Hcs24 interacts with the cytoskeletal protein actin in chondrocytes. Biochem Biophys Res Commun. 2002 Dec 20; 299(5):755-61. PMID: 12470643.
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    31. Nawachi K, Inoue M, Kubota S, Nishida T, Yosimichi G, Nakanishi T, Kanyama M, Kuboki T, Yatani H, Yamaai T, Takigawa M. Tyrosine kinase-type receptor ErbB4 in chondrocytes: interaction with connective tissue growth factor and distribution in cartilage. FEBS Lett. 2002 Sep 25; 528(1-3):109-13. PMID: 12297288.
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    32. Eguchi T, Kubota S, Kondo S, Kuboki T, Yatani H, Takigawa M. A novel cis-element that enhances connective tissue growth factor gene expression in chondrocytic cells. Biochem Biophys Res Commun. 2002 Jul 12; 295(2):445-51. PMID: 12150969.
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    33. Fang J, Kubota S, Pomerantz RJ. A trans-dominant negative HIV type 1 Rev with intact domains of NLS/NOS and NES. AIDS Res Hum Retroviruses. 2002 Jul 01; 18(10):705-9. PMID: 12167277.
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    34. Kubota S. The extinction program for Homo sapiens and cloning humans: trinucleotide expansion as a one-way track to extinction. Med Hypotheses. 2001 Mar; 56(3):296-301. PMID: 11359350.
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    35. Kubota S, Pomerantz RJ. The nuclear function of the nuclear diffusion inhibitory signal of human immunodeficiency virus type 1: critical roles in dominant nuclear localization and intracellular stability. J Hum Virol. 2000 Jul-Aug; 3(4):173-81. PMID: 10990165.
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    36. Kubota S, Zhang H, Kitahara S, Pomerantz RJ. Role of lentiviral lytic polypeptide I (LLP-I) in the selective cytotoxicity of gamma-glutamylcysteine ethyl ester against human immunodeficiency virus type 1-producing cells. Antivir Chem Chemother. 1999 May; 10(3):121-7. PMID: 10431611.
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    37. Kubota S, Copeland TD, Pomerantz RJ. Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins. Oncogene. 1999 Feb 18; 18(7):1503-14. PMID: 10050887.
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    38. Kubota S, Shetty S, Zhang H, Kitahara S, Pomerantz RJ. Novel inhibitory effects of gamma-glutamylcysteine ethyl ester against human immunodeficiency virus type 1 production and propagation. Antimicrob Agents Chemother. 1998 May; 42(5):1200-6. PMID: 9593150.
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    39. Kubota S, Pomerantz RJ. A cis-acting peptide signal in human immunodeficiency virus type I Rev which inhibits nuclear entry of small proteins. Oncogene. 1998 Apr 09; 16(14):1851-61. PMID: 9583682.
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    40. Kubota S, Furuta RA, Hatanaka M, Pomerantz RJ. Modulation of HTLV-I gene expression by HIV-1 Rev through an alternative RxRE-independent pathway mediated by the RU5 portion of the 5'-LTR. Biochem Biophys Res Commun. 1998 Feb 04; 243(1):79-85. PMID: 9473483.
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    41. Kubota S, Hatanaka M, Pomerantz RJ. Nucleo-cytoplasmic redistribution of the HTLV-I Rex protein: alterations by coexpression of the HTLV-I p21x protein. Virology. 1996 Jun 15; 220(2):502-7. PMID: 8661402.
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    42. Wu Y, Duan L, Zhu M, Hu B, Kubota S, Bagasra O, Pomerantz RJ. Binding of intracellular anti-Rev single chain variable fragments to different epitopes of human immunodeficiency virus type 1 rev: variations in viral inhibition. J Virol. 1996 May; 70(5):3290-7. PMID: 8627813.
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    43. Kubota S, Siomi H, Hatanaka M, Pomerantz RJ. Cis/trans-activation of the interleukin-9 receptor gene in an HTLV-I-transformed human lymphocytic cell. Oncogene. 1996 Apr 04; 12(7):1441-7. PMID: 8622860.
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    44. Kubota S, Duan L, Furuta RA, Hatanaka M, Pomerantz RJ. Nuclear preservation and cytoplasmic degradation of human immunodeficiency virus type 1 Rev protein. J Virol. 1996 Feb; 70(2):1282-7. PMID: 8551596.
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