Markku Miettinen

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address1025 Walnut St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kaczorowski M, Ylaya K, Chlopek M, Taniyama D, Pommier Y, Lasota J, Miettinen M. Immunohistochemical Evaluation of Schlafen 11 (SLFN11) Expression in Cancer in the Search of Biomarker-Informed Treatment Targets: A Study of 127 Entities Represented by 6658 Tumors. Am J Surg Pathol. 2024 Aug 26. PMID: 39185596.
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    2. Kaczorowski M, Lasota J, Halon A, Miettinen M. H3K27me3 Immunohistochemistry Reveals a Dotlike Expression Pattern Archetypal for Female Origin in Testicular Germ Cell Tumors. Arch Pathol Lab Med. 2024 Aug 23. PMID: 39175461.
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    3. Kato S, Koshino A, Lasota J, Komura M, Wang C, Ebi M, Ogasawara N, Kojima K, Tsuzuki T, Kasai K, Takahashi S, Miettinen M, Kasugai K, Inaguma S. Use of SATB2 and CDX2 Immunohistochemistry to Characterize and Diagnose Colorectal Cancer. Appl Immunohistochem Mol Morphol. 2024 Jul 30. PMID: 39076030.
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    4. Lasota J, Thompson LDR, Chlopek M, Kowalik A, Miettinen M. Unusual PEComa With PRCC::TFE3 Fusion Mimicking Sinonasal Tract Melanoma. Appl Immunohistochem Mol Morphol. 2024 Jul 08. PMID: 38975712.
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    5. Desai P, Takahashi N, Kumar R, Nichols S, Malin J, Hunt A, Schultz C, Cao Y, Tillo D, Nousome D, Chauhan L, Sciuto L, Jordan K, Rajapakse V, Tandon M, Lissa D, Zhang Y, Kumar S, Pongor L, Singh A, Schroder B, Sharma AK, Chang T, Vilimas R, Pinkiert D, Graham C, Butcher D, Warner A, Sebastian R, Mahon M, Baker K, Cheng J, Berger A, Lake R, Abel M, Krishnamurthy M, Chrisafis G, Fitzgerald P, Nirula M, Goyal S, Atkinson D, Bateman NW, Abulez T, Nair G, Apolo A, Guha U, Karim B, El Meskini R, Ohler ZW, Jolly MK, Schaffer A, Ruppin E, Kleiner D, Miettinen M, Brown GT, Hewitt S, Conrads T, Thomas A. Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities. Cell Rep Med. 2024 Jun 18; 5(6):101610. PMID: 38897168.
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    6. Raygada M, John L, Liu A, Schultz J, Thomas BJ, Bernstein D, Miettinen M, Raffeld M, Xi L, Tyagi M, Aldape K, Glod J, Reilly KM, Widemann BC, Wedekind MF. Germline findings in cancer predisposing genes from a small cohort of chordoma patients. J Cancer Res Clin Oncol. 2024 May 03; 150(5):227. PMID: 38700789.
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    7. Inaguma S, Wang C, Ito S, Ueki A, Lasota J, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okon K, Biernat W, Takiguchi S, Schrump DS, Miettinen M, Takahashi S. Characterization of pleural mesothelioma by hierarchical clustering analyses using immune cells within tumor microenvironment. Pathobiology. 2024 Mar 25. PMID: 38527431.
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    8. Kaczorowski M, Lasota J, Dudek K, Malkiewicz B, Miettinen M, Halon A. Expression of Immunotherapy Target PRAME in Cancer Correlates with Histone H3 Acetylation and Is Unrelated to Expression of Methylating (DMNT3A/3B) and Demethylating (TET1) Enzymes. J Clin Med. 2024 Mar 08; 13(6). PMID: 38541782.
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    9. Ahmed S, Wedekind MF, Del Rivero J, Raygada M, Lockridge R, Glod JW, Flowers C, Thomas BJ, Bernstein DB, Kapustina OB, Jain A, Miettinen M, Raffeld M, Xi L, Tyagi M, Kim J, Aldape K, Malayeri AA, Kaplan RN, Allen T, Vivelo CA, Sandler AB, Widemann BC, Reilly KM. Longitudinal Natural History Study of Children and Adults with Rare Solid Tumors: Initial Results for First 200 Participants. Cancer Res Commun. 2023 Nov 15. PMID: 37966258.
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    10. Mason JB, Ozdemirli M, Miettinen M, Gupta M. Case of NUTM::CIC fusion sarcoma surrounding inflatable penile prosthesis. Urol Case Rep. 2023 Nov; 51:102617. PMID: 38046259.
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    11. Miettinen M, Abdullaev Z, Turakulov R, Quezado M, Lui?a Contreras A, Curcio CA, Rys J, Chlopek M, Lasota J, Aldape KD. Assessment of The Utility of The Sarcoma DNA Methylation Classifier In Surgical Pathology. Am J Surg Pathol. 2023 Nov 03. PMID: 37921028.
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    12. Lasota J, Chlopek M, Kaczorowski M, Nat?lie K, Rys J, Kopczynski J, Sulaieva O, Michal M, Kruczak A, Harazin-Lechowska A, Szczepaniak M, Koshyk O, Halon A, Czapiewski P, Abdullaev Z, Kowalik A, Aldape KD, Michal M, Miettinen M. Utility of Immunohistochemistry With Antibodies to SS18-SSX Chimeric Proteins and C-Terminus of SSX Protein for Synovial Sarcoma Differential Diagnosis. Am J Surg Pathol. 2023 Oct 27. PMID: 37899499.
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    13. Green BL, Gamble LA, Diggs LP, Nousome D, Patterson JC, Joughin BA, Gasmi B, Lux SC, Samaranayake SG, Miettinen M, Quezado M, Hernandez JM, Yaffe MB, Davis JL. Early immune changes support signet ring cell dormancy in CDH1-driven hereditary diffuse gastric carcinogenesis. Mol Cancer Res. 2023 Sep 14. PMID: 37707375.
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    14. Akshintala S, Sundby RT, Bernstein D, Glod JW, Kaplan RN, Yohe ME, Gross AM, Derdak J, Lei H, Pan A, Dombi E, Palacio-Yance I, Herrera KR, Miettinen MM, Chen HX, Steinberg SM, Helman LJ, Mascarenhas L, Widemann BC, Navid F, Shern JF, Heske CM. Phase I trial of ganitumab plus dasatinib to cotarget the insulin-like growth factor 1 receptor and Src family kinase YES in rhabdomyosarcoma. Clin Cancer Res. 2023 Jul 03. PMID: 37398992.
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    15. John L, Smith H, Ilanchezhian M, Lockridge R, Reilly KM, Raygada M, Dombi E, Sandler A, Thomas BJ, Glod J, Miettinen M, Allen T, Sommer J, Levy J, Lozinsky S, Dix D, Bouffet E, MacDonald S, Mukherjee D, Snyderman CH, Rowan NR, Malyapa R, Park DM, Heery C, Gardner PA, Cote GM, Fuller S, Butman JA, Jackson S, Gulley JL, Widemann BC, Wedekind MF. The NIH pediatric/young adult chordoma clinic and natural history study: Making advances in a very rare tumor. Pediatr Blood Cancer. 2023 Jun 22; e30358. PMID: 37347686.
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    16. Gross JM, Perret R, Coindre JM, Le Loarer F, Michal M, Michal M, Miettinen M, McCabe CE, Nair AA, Swanson AA, Thangaiah JJ, Torres-Mora J, Bonadio A, Voltaggio L, Epstein JI, Gupta S, Folpe AL, Schoolmeester JK. Lipoblastoma-Like Tumor and Fibrosarcoma-Like Lipomatous Neoplasm Represent the Same Entity: A Clinicopathologic and Molecular Genetic Study of 23 Cases Occurring in Both Men and Women at Diverse Locations. Mod Pathol. 2023 Jun 10; 36(9):100246. PMID: 37307874.
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    17. Cole CB, Morelli MP, Fantini M, Miettinen M, Fetsch P, Peer C, Figg WD, Yin T, Houston N, McCoy A, Lipkowitz S, Zimmer A, Lee JM, Pavelova M, Villanueva EN, Trewhitt K, Solarz BB, Fergusson M, Mavroukakis SA, Zaki A, Tsang KY, Arlen PM, Annunziata CM. Correction: First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors. J Exp Clin Cancer Res. 2023 Apr 26; 42(1):102. PMID: 37101182.
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    18. Gubbiotti MA, Dhillon KS, Harris J, Kothari S, Ware JB, Desai A, Shabason J, Miettinen M, Quezado M, Aldape K, Judy K, Wang ZX, Curtis MT, Nasrallah MP. An unusual case of metastatic diffuse midline glioma in an adult. J Neuropathol Exp Neurol. 2023 Apr 19. PMID: 37075315.
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    19. Asif B, Sarvestani AL, Gamble LA, Samaranayake SG, Famiglietti AL, Fasaye GA, Quezado M, Miettinen M, Korman L, Koh C, Heller T, Davis JL. Cancer surveillance as an alternative to prophylactic total gastrectomy in hereditary diffuse gastric cancer: a prospective cohort study. Lancet Oncol. 2023 04; 24(4):383-391. PMID: 36990610.
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    20. Cole CB, Morelli MP, Fantini M, Miettinen M, Fetsch P, Peer C, Figg WD, Yin T, Houston N, McCoy A, Lipkowitz S, Zimmer A, Lee JM, Pavelova M, Villanueva EN, Trewhitt K, Solarz BB, Fergusson M, Mavroukakis SA, Zaki A, Tsang KY, Arlen PM, Annunziata CM. First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors. J Exp Clin Cancer Res. 2023 Mar 29; 42(1):76. PMID: 36991390.
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    21. Nair NU, Jiang Q, Wei JS, Misra VA, Morrow B, Kesserwan C, Hermida LC, Lee JS, Mian I, Zhang J, Lebensohn A, Miettinen M, Sengupta M, Khan J, Ruppin E, Hassan R. Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma. Cell Rep Med. 2023 Feb 21; 4(2):100938. PMID: 36773602.
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    22. Inaguma S, Ueki A, Lasota J, Komura M, Sheema AN, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okon K, Biernat W, Schrump DS, Hassan R, Miettinen M, Takahashi S. CD70 and PD-L1 (CD274) co-expression predicts poor clinical outcomes in patients with pleural mesothelioma. J Pathol Clin Res. 2023 Feb 08. PMID: 36754859.
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    23. Ligon JA, Sundby RT, Wedekind MF, Arnaldez FI, Del Rivero J, Wiener L, Srinivasan R, Spencer M, Carbonell A, Lei H, Shern J, Steinberg SM, Figg WD, Peer CJ, Zimmerman S, Moraly J, Xu X, Fox S, Chan K, Barbato MI, Andresson T, Taylor N, Pacak K, Killian JK, Dombi E, Linehan WM, Miettinen M, Piekarz R, Helman LJ, Meltzer P, Widemann B, Glod J. A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma. Clin Cancer Res. 2023 01 17; 29(2):341-348. PMID: 36302175.
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    24. Chen CG, Aldape K, Dhillon KS, Laske DW, Abdullaev Z, Marotta DA, Miettinen M, Curtis MT. DNA methylation profiling and histologic analysis of sellar TTF-1-positive papillary epithelial tumor supports a novel CNS entity. J Neuropathol Exp Neurol. 2022 12 19; 82(1):96-98. PMID: 36367825.
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    25. Passi M, Gamble LA, Samaranayake SG, Schueler SA, Curtin BF, Fasaye GA, Bowden C, Gurram S, Quezado M, Miettinen M, Koh C, Heller T, Davis JL. Association of CDH1 Germline Variants and Colon Polyp Phenotypes in Patients with Hereditary Diffuse Gastric Cancer. Gastro Hep Adv. 2023; 2(2):244-251. PMID: 36776716.
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    26. Lopez DC, Robbins YL, Kowalczyk JT, Lassoued W, Gulley JL, Miettinen MM, Gallia GL, Allen CT, Hodge JW, London NR. Multi-spectral immunofluorescence evaluation of the myeloid, T cell, and natural killer cell tumor immune microenvironment in chordoma may guide immunotherapeutic strategies. Front Oncol. 2022; 12:1012058. PMID: 36338744.
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    27. Hornick JL, Webster F, Dei Tos AP, Hemmings C, Miettinen M, Oda Y, Raut CP, Rubin BP, Von Mehren M, Wardelmann E, Fletcher CDM. Dataset for reporting of gastrointestinal stromal tumours: recommendations from the International Collaboration on Cancer Reporting (ICCR). Histopathology. 2023 Feb; 82(3):376-384. PMID: 36073677.
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    28. Chlopek M, Lasota J, Thompson LDR, Szczepaniak M, Kuzniacka A, Hincza K, Kubicka K, Kaczorowski M, Newford M, Liu Y, Agaimy A, Biernat W, Durzynska M, Dziuba I, Hartmann A, Inaguma S, Izycka-Swieszewska E, Kato H, Kopczynski J, Michal M, Michal M, Peksa R, Prochorec-Sobieszek M, Starzynska A, Takahashi S, Wasag B, Kowalik A, Miettinen M. Alterations in key signaling pathways in sinonasal tract melanoma. A molecular genetics and immunohistochemical study of 90 cases and comprehensive review of the literature. Mod Pathol. 2022 11; 35(11):1609-1617. PMID: 35978013.
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    29. Kaczorowski M, Chlopek M, Kruczak A, Rys J, Lasota J, Miettinen M. PRAME Expression in Cancer. A Systematic Immunohistochemical Study of >5800 Epithelial and Nonepithelial Tumors. Am J Surg Pathol. 2022 11 01; 46(11):1467-1476. PMID: 35973038.
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    30. Patel M, Jha A, Ling A, Chen CC, Millo C, Kuo MJM, Nazari MA, Talvacchio S, Charles K, Miettinen M, Del Rivero J, Chen AP, Nilubol N, Lin FI, Civelek AC, Ta?eb D, Carrasquillo JA, Pacak K. Performances of Functional and Anatomic Imaging Modalities in Succinate Dehydrogenase A-Related Metastatic Pheochromocytoma and Paraganglioma. Cancers (Basel). 2022 Aug 11; 14(16). PMID: 36010880.
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    31. Tomar S, Zhang J, Khanal M, Hong J, Venugopalan A, Jiang Q, Sengupta M, Miettinen M, Li N, Pastan I, Ho M, Hassan R. Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors. Mol Cancer Ther. 2022 07 05; 21(7):1195-1206. PMID: 35499461.
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    32. Cudrici CD, Newman KA, Ferrante EA, Huffstutler R, Carney K, Betancourt B, Miettinen M, Siegel R, Katz JD, Nesti LJ, St Hilaire C, Lakshmipathy D, Wen H, Bagheri MH, Boehm M, Brofferio A. Multifocal calcific periarthritis with distinctive clinical and radiological features in patients with CD73 deficiency. Rheumatology (Oxford). 2021 12 24; 61(1):163-173. PMID: 33744914.
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    33. Maeng HM, Moore BN, Bagheri H, Steinberg SM, Inglefield J, Dunham K, Wei WZ, Morris JC, Terabe M, England LC, Roberson B, Rosing D, Sachdev V, Pack SD, Miettinen MM, Barr FG, Weiner LM, Panch S, Stroncek DF, Wood LV, Berzofsky JA. Phase I Clinical Trial of an Autologous Dendritic Cell Vaccine Against HER2 Shows Safety and Preliminary Clinical Efficacy. Front Oncol. 2021; 11:789078. PMID: 34976830.
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    34. Luo W, Stevens TM, Stafford P, Miettinen M, Gatalica Z, Vranic S. NUTM1-Rearranged Neoplasms-A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations-An Updated Review. Curr Oncol. 2021 11 07; 28(6):4485-4503. PMID: 34898574.
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    35. Vit O, Patel M, Musil Z, Hartmann I, Frysak Z, Miettinen M, Pacak K, Petrak J. Deep Membrane Proteome Profiling Reveals Overexpression of Prostate-Specific Membrane Antigen (PSMA) in High-Risk Human Paraganglioma and Pheochromocytoma, Suggesting New Theranostic Opportunity. Molecules. 2021 Oct 29; 26(21). PMID: 34770976.
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    36. Hu ZI, Miettinen M, Quezado M, Lebensohn AP, Aldape K, Agra M, Wagner C, Mallory Y, Hassan R, Ghafoor A. Meningiomas in Patients With Malignant Pleural Mesothelioma Harboring Germline BAP1 Mutations. J Thorac Oncol. 2022 03; 17(3):461-466. PMID: 34628055.
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    37. Qu S, Fetsch P, Thomas A, Pommier Y, Schrump DS, Miettinen MM, Chen H. Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers. J Thorac Oncol. 2022 01; 17(1):141-153. PMID: 34534680.
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    38. Zhang M, Hong JA, Kunst TF, Bond CD, Kenney CM, Warga CL, Yeray J, Lee MJ, Yuno A, Lee S, Miettinen M, Ripley RT, Hoang CD, Gnjatic S, Trepel JB, Schrump DS. Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies. Transl Lung Cancer Res. 2021 Jul; 10(7):3079-3092. PMID: 34430349.
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    39. Schueler SA, Gamble LA, Curtin BF, Ruff SM, Connolly M, Hannah C, Quezado M, Miettinen M, George M, Blakely AM, Hernandez JM, Heller T, Koh C, Davis JL. Evaluation of confocal laser endomicroscopy for detection of occult gastric carcinoma in CDH1 variant carriers. J Gastrointest Oncol. 2021 Apr; 12(2):216-225. PMID: 34012620.
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    40. Golmard L, Vasta LM, Duflos V, Corsini C, Dubois d'Enghien C, McMaster ML, Harney LA, Carr AG, Ling A, Dijoud F, Gauthier A, Miettinen M, Cost NG, Gauthier-Villars M, Orbach D, Irtan S, Haouy S, Schultz KA, Stoppa-Lyonnet D, Coupier I, Stewart DR, Sirvent N. Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features of DICER1 syndrome. J Med Genet. 2022 04; 59(4):346-350. PMID: 33782093.
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    41. Torres MB, Diggs LP, Wei JS, Khan J, Miettinen M, Fasaye GA, Gillespie A, Widemann BC, Kaplan RN, Davis JL, Hernandez JM, Rivero JD. Ataxia telangiectasia mutated germline pathogenic variant in adrenocortical carcinoma. Cancer Genet. 2021 08; 256-257:21-25. PMID: 33836455.
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    42. Raygada M, Raffeld M, Bernstein A, Miettinen M, Glod J, Hughes MS, Reilly K, Widemann B, Del Rivero J. Case report of adrenocortical carcinoma associated with double germline mutations in MSH2 and RET. Am J Med Genet A. 2021 04; 185(4):1282-1287. PMID: 33615670.
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    43. Kruslin B, Gatalica Z, Hes O, Skenderi F, Miettinen M, Contreras E, Xiu J, Ellis M, Florento E, Vranic S, Swensen J. TERT Gene Fusions Characterize a Subset of Metastatic Leydig Cell Tumors. Clin Genitourin Cancer. 2021 08; 19(4):333-338. PMID: 33741265.
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    44. Chamberlin M, Khan S, Hernandez C, Miettinen M, Wei JS, Khan J, Glod J, Rowe L, Kaushal A. Aneurysmal Fibrous Histiocytoma: A Large Soft Tissue Tumor with Metastases Treated with Palliative Radiation Therapy and Targeted Therapy. Case Rep Oncol. 2021 Jan-Apr; 14(1):17-23. PMID: 38352276.
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    45. Curtin BF, Gamble LA, Schueler SA, Ruff SM, Quezado M, Miettinen M, Fasaye GA, Passi M, Hernandez JM, Heller T, Koh C, Davis JL. Enhanced endoscopic detection of occult gastric cancer in carriers of pathogenic CDH1 variants. J Gastroenterol. 2021 02; 56(2):139-146. PMID: 33206267.
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    46. Hassan R, Miettinen M. Response to Letter to Editor by Cornelissen et?al. J Thorac Oncol. 2020 10; 15(10):e169-e170. PMID: 32981607.
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    47. Reardon ES, Shukla V, Xi S, Gara SK, Liu Y, Straughan D, Zhang M, Hong JA, Payabyab EC, Kumari A, Richards WG, De Rienzo A, Hassan R, Miettinen M, Xi L, Raffeld M, Uechi LT, Li X, Wang R, Chen H, Hoang CD, Bueno R, Schrump DS. UHRF1 Is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma. J Thorac Oncol. 2021 01; 16(1):89-103. PMID: 32927122.
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    48. Lasota J, Chlopek M, Wasag B, Kowalik A, Christiansen J, Lamoureux J, Kuzniacka A, Felisiak-Golabek A, Liu Y, Reyes TAR, Saha R, Agaimy A, Behenska K, Biernat W, Cattaneo L, Centonze G, Daum O, Daumova M, Domagala P, Dziuba I, Geppert CE, G?zdz S, Nasierowska-Guttmejer A, Halon A, Hartmann A, Inaguma S, Izycka-Swieszewska E, Kaczorowski M, Kolos M, Kopczynski J, Michal M, Milione M, Okon K, Peksa R, Pyzlak M, Rys J, Waloszczyk P, Wejman J, Miettinen M. Colorectal Adenocarcinomas Harboring ALK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 12 Cases and Review of the Literature. Am J Surg Pathol. 2020 09; 44(9):1224-1234. PMID: 32804454.
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    49. Mamilla D, Manukyan I, Fetsch PA, Pacak K, Miettinen M. Immunohistochemical distinction of paragangliomas from epithelial neuroendocrine tumors-gangliocytic duodenal and cauda equina paragangliomas align with epithelial neuroendocrine tumors. Hum Pathol. 2020 09; 103:72-82. PMID: 32668278.
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    50. Vasta LM, Nichols A, Harney LA, Best AF, Carr AG, Harris AK, Miettinen M, Schultz KAP, Kim HJ, Stewart DR. Nasal chondromesenchymal hamartomas in a cohort with pathogenic germline variation in DICER1. Rhinol Online. 2020; 3:15-24. PMID: 34164613.
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    51. Rosenblum JS, Cappadona AJ, Argersinger DP, Pang Y, Wang H, Nazari MA, Munasinghe JP, Donahue DR, Jha A, Smirniotopoulos JG, Miettinen MM, Knutsen RH, Kozel BA, Zhuang Z, Pacak K, Heiss JD. Neuraxial dysraphism in EPAS1-associated syndrome due to improper mesenchymal transition. Neurol Genet. 2020 Jun; 6(3):e414. PMID: 32337341.
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    52. Lasota J, Chlopek M, Lamoureux J, Christiansen J, Kowalik A, Wasag B, Felisiak-Golabek A, Agaimy A, Biernat W, Canzonieri V, Centonze G, Chmielik E, Daum O, Dubov? M, Dziuba I, Goertz S, G?zdz S, Guttmejer-Nasierowska A, Haglund C, Halon A, Hartmann A, Inaguma S, Izycka-Swieszewska E, Kaczorowski M, Kita P, Kolos M, Kopczynski J, Michal M, Milione M, Okon K, Peksa R, Pyzlak M, Ristim?ki A, Rys J, Szostak B, Szpor J, Szumilo J, Teresinski L, Waloszczyk P, Wejman J, Wesolowski W, Miettinen M. Colonic Adenocarcinomas Harboring NTRK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 16 Cases and Review of the Literature. Am J Surg Pathol. 2020 02; 44(2):162-173. PMID: 31567189.
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    53. Inaguma S, Lasota J, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okon K, Biernat W, Schrump DS, Hassan R, Kasai K, Miettinen M, Ikeda H. CD70 expression correlates with a worse prognosis in malignant pleural mesothelioma patients via immune evasion and enhanced invasiveness. J Pathol. 2020 02; 250(2):205-216. PMID: 31639216.
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    54. Mian I, Abdullaev Z, Morrow B, Kaplan RN, Gao S, Miettinen M, Schrump DS, Zgonc V, Wei JS, Khan J, Pack S, Hassan R. Anaplastic Lymphoma Kinase Gene Rearrangement in Children and Young Adults With Mesothelioma. J Thorac Oncol. 2020 03; 15(3):457-461. PMID: 31783178.
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    55. Nelson CN, Dombi E, Rosenblum JS, Miettinen MM, Lehky TJ, Whitcomb PO, Hayes C, Scott G, Benzo S, Widemann BC, Chittiboina P. Safe marginal resection of atypical neurofibromas in neurofibromatosis type 1. J Neurosurg. 2019 Oct 25; 1-11. PMID: 31653805.
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    56. Glod J, Arnaldez FI, Wiener L, Spencer M, Killian JK, Meltzer P, Dombi E, Derse-Anthony C, Derdak J, Srinivasan R, Linehan WM, Miettinen M, Steinberg SM, Helman L, Widemann BC. A Phase II Trial of Vandetanib in Children and Adults with Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor. Clin Cancer Res. 2019 11 01; 25(21):6302-6308. PMID: 31439578.
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    57. Pemov A, Hansen NF, Sindiri S, Patidar R, Higham CS, Dombi E, Miettinen MM, Fetsch P, Brems H, Chandrasekharappa SC, Jones K, Zhu B, Wei JS, Mullikin JC, Wallace MR, Khan J, Legius E, Widemann BC, Stewart DR. Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1-associated atypical neurofibromas. Neuro Oncol. 2019 08 05; 21(8):981-992. PMID: 30722027.
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    58. Banerjee S, Corless CL, Miettinen MM, Noh S, Ustoy R, Davis JL, Tang CM, Yebra M, Burgoyne AM, Sicklick JK. Loss of the PTCH1 tumor suppressor defines a new subset of plexiform fibromyxoma. J Transl Med. 2019 07 30; 17(1):246. PMID: 31362756.
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    59. Kobayashi M, Inaguma S, Raffeld M, Kato H, Suzuki S, Wakasugi T, Mitsui A, Kuwabara Y, Lasota J, Ikeda H, Miettinen M, Takahashi S. Epithelioid variant of gastrointestinal stromal tumor harboring PDGFRA mutation and MLH1 gene alteration: A case report. Pathol Int. 2019 Sep; 69(9):541-546. PMID: 31273885.
      Citations:    
    60. Murai J, Thomas A, Miettinen M, Pommier Y. Schlafen 11 (SLFN11), a restriction factor for replicative stress induced by DNA-targeting anti-cancer therapies. Pharmacol Ther. 2019 09; 201:94-102. PMID: 31128155.
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    61. Caisova V, Li L, Gupta G, Jochmanova I, Jha A, Uher O, Huynh TT, Miettinen M, Pang Y, Abunimer L, Niu G, Chen X, Ghayee HK, Ta?eb D, Zhuang Z, Zenka J, Pacak K. The Significant Reduction or Complete Eradication of Subcutaneous and Metastatic Lesions in a Pheochromocytoma Mouse Model after Immunotherapy Using Mannan-BAM, TLR Ligands, and Anti-CD40. Cancers (Basel). 2019 May 11; 11(5). PMID: 31083581.
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    62. Andreasen S, Varma S, Barasch N, Thompson LDR, Miettinen M, Rooper L, Stelow EB, Agander TK, Seethala RR, Chiosea SI, Hom?e P, Wessel I, Larsen SR, Erentaite D, Bishop JA, Ulh?i BP, Kiss K, Melchior LC, Pollack JR, West RB. The HTN3-MSANTD3 Fusion Gene Defines a Subset of Acinic Cell Carcinoma of the Salivary Gland. Am J Surg Pathol. 2019 04; 43(4):489-496. PMID: 30520817.
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    63. Abdul Sater Z, Jha A, Mandl A, Mangelen SK, Carrasquillo JA, Ling A, Gonzales MK, Lopes Abath Neto O, Miettinen M, Adams KT, Nockel P, El Lakis M, Pacak K. Gallbladder Paraganglioma Associated with SDHD Mutation: a Potential Pitfall on 18F-FDOPA PET Imaging. Nucl Med Mol Imaging. 2019 Apr; 53(2):144-147. PMID: 31057686.
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    64. Lasota J, Kowalik A, Felisiak-Golabek A, Zieba S, Waloszczyk P, Masiuk M, Wejman J, Szumilo J, Miettinen M. Primary malignant melanoma of esophagus: clinicopathologic characterization of 20 cases including molecular genetic profiling of 15 tumors. Mod Pathol. 2019 07; 32(7):957-966. PMID: 30760858.
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    65. Lo W, Zhu B, Sabesan A, Wu HH, Powers A, Sorber RA, Ravichandran S, Chen I, McDuffie LA, Quadri HS, Beane JD, Calzone K, Miettinen MM, Hewitt SM, Koh C, Heller T, Wacholder S, Rudloff U. Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC). J Med Genet. 2019 06; 56(6):370-379. PMID: 30745422.
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    66. Stevens TM, Morlote D, Xiu J, Swensen J, Brandwein-Weber M, Miettinen MM, Gatalica Z, Bridge JA. NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum. Mod Pathol. 2019 06; 32(6):764-773. PMID: 30723300.
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    67. Miettinen M, Felisiak-Golabek A, Lui?a Contreras A, Glod J, Kaplan RN, Killian JK, Lasota J. New fusion sarcomas: histopathology and clinical significance of selected entities. Hum Pathol. 2019 04; 86:57-65. PMID: 30633925.
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    68. Lasota J, Kowalik A, Felisiak-Golabek A, Zieba S, Wang ZF, Miettinen M. New Mechanisms of mTOR Pathway Activation in KIT-mutant Malignant GISTs. Appl Immunohistochem Mol Morphol. 2019 01; 27(1):54-58. PMID: 28777148.
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    69. Leijon H, Remes S, Hagstr?m J, Louhimo J, M?enp?? H, Schalin-J?ntti C, Miettinen M, Haglund C, Arola J. Variable somatostatin receptor subtype expression in 151 primary pheochromocytomas and paragangliomas. Hum Pathol. 2019 04; 86:66-75. PMID: 30529752.
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    70. Jha S, Fratzl-Zelman N, Roschger P, Papadakis GZ, Cowen EW, Kang H, Lehky TJ, Alter K, Deng Z, Ivovic A, Flynn L, Reynolds JC, Dasgupta A, Miettinen M, Lange E, Katz J, Klaushofer K, Marini JC, Siegel RM, Bhattacharyya T. Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations. J Bone Miner Res. 2019 01; 34(1):145-156. PMID: 30138550.
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    71. Higham CS, Dombi E, Rogiers A, Bhaumik S, Pans S, Connor SEJ, Miettinen M, Sciot R, Tirabosco R, Brems H, Baldwin A, Legius E, Widemann BC, Ferner RE. The characteristics of 76 atypical neurofibromas as precursors to neurofibromatosis 1 associated malignant peripheral nerve sheath tumors. Neuro Oncol. 2018 05 18; 20(6):818-825. PMID: 29409029.
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    72. Kindler HL, Ismaila N, Armato SG, Bueno R, Hesdorffer M, Jahan T, Jones CM, Miettinen M, Pass H, Rimner A, Rusch V, Sterman D, Thomas A, Hassan R. Treatment of Malignant Pleural Mesothelioma: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol. 2018 05 01; 36(13):1343-1373. PMID: 29346042.
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    73. Felisiak-Golabek A, Inaguma S, Kowalik A, Wasag B, Wang ZF, Zieba S, Pieciak L, Rys J, Kopczynski J, Sarlomo-Rikala M, G?zdz S, Lasota J, Miettinen M. SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma. Appl Immunohistochem Mol Morphol. 2018 Jan; 26(1):40-45. PMID: 29206715.
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    74. Leijon H, Kaprio T, Heiskanen A, Satomaa T, Hiltunen JO, Miettinen MM, Arola J, Haglund C. N-Glycomic Profiling of Pheochromocytomas and Paragangliomas Separates Metastatic and Nonmetastatic Disease. J Clin Endocrinol Metab. 2017 11 01; 102(11):3990-4000. PMID: 28938401.
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    75. Inaguma S, Lasota J, Felisiak-Golabek A, Kowalik A, Wang Z, Zieba S, Kalisz J, Ikeda H, Miettinen M. Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD-L1 (CD274)-expression: Possible roles of tumour micro environmental factors for CD274 expression. J Pathol Clin Res. 2017 Oct; 3(4):268-278. PMID: 29085667.
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    76. Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson HS, Reardon ES, McLoughlin KC, Kaufman AS, Payabyab EC, Hong JA, Zhang M, Davis S, Edelman D, Chen G, Miettinen MM, Restifo NP, Ried T, Meltzer PA, Schrump DS. ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Res. 2017 11 15; 77(22):6267-6281. PMID: 28935813.
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    77. Murgai M, Ju W, Eason M, Kline J, Beury DW, Kaczanowska S, Miettinen MM, Kruhlak M, Lei H, Shern JF, Cherepanova OA, Owens GK, Kaplan RN. KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis. Nat Med. 2017 Oct; 23(10):1176-1190. PMID: 28920957.
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    78. Thompson LDR, Jo VY, Agaimy A, Llombart-Bosch A, Morales GN, Machado I, Flucke U, Wakely PE, Miettinen M, Bishop JA. Sinonasal Tract Alveolar Rhabdomyosarcoma in Adults: A Clinicopathologic and Immunophenotypic Study of Fifty-Two Cases with Emphasis on Epithelial Immunoreactivity. Head Neck Pathol. 2018 Jun; 12(2):181-192. PMID: 28875443.
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    79. Inaguma S, Lasota J, Wang Z, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okon K, Biernat W, Ikeda H, Schrump DS, Hassan R, Miettinen M. Expression of ALCAM (CD166) and PD-L1 (CD274) independently predicts shorter survival in malignant pleural mesothelioma. Hum Pathol. 2018 01; 71:1-7. PMID: 28811252.
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    80. Reilly KM, Kim A, Blakely J, Ferner RE, Gutmann DH, Legius E, Miettinen MM, Randall RL, Ratner N, Jumb? NL, Bakker A, Viskochil D, Widemann BC, Stewart DR. Neurofibromatosis Type 1-Associated MPNST State of the Science: Outlining a Research Agenda for the Future. J Natl Cancer Inst. 2017 08 01; 109(8). PMID: 29117388.
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    81. Quadri HS, Aiken TJ, Allgaeuer M, Moravec R, Altekruse S, Hussain SP, Miettinen MM, Hewitt SM, Rudloff U. Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer. BMC Cancer. 2017 Jul 21; 17(1):495. PMID: 28732488.
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    82. Miettinen MM, Antonescu CR, Fletcher CDM, Kim A, Lazar AJ, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A. Histopathologic evaluation of atypical neurofibromatous tumors and their transformation into malignant peripheral nerve sheath tumor in patients with neurofibromatosis 1-a consensus overview. Hum Pathol. 2017 09; 67:1-10. PMID: 28551330.
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    83. Kim A, Stewart DR, Reilly KM, Viskochil D, Miettinen MM, Widemann BC. Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies. Sarcoma. 2017; 2017:7429697. PMID: 28592921.
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    84. Miettinen M, Felisiak-Golabek A, Wang Z, Inaguma S, Lasota J. GIST Manifesting as a Retroperitoneal Tumor: Clinicopathologic Immunohistochemical, and Molecular Genetic Study of 112 Cases. Am J Surg Pathol. 2017 May; 41(5):577-585. PMID: 28288036.
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    85. Levy AD, Manning MA, Miettinen MM. Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 2-Uncommon Sarcomas. Radiographics. 2017 May-Jun; 37(3):797-812. PMID: 28493803.
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    86. Inaguma S, Wang Z, Lasota J, Onda M, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okon K, Biernat W, Ikeda H, Schrump DS, Hassan R, Pastan I, Miettinen M. Comprehensive immunohistochemical study of mesothelin (MSLN) using different monoclonal antibodies 5B2 and MN-1 in 1562 tumors with evaluation of its prognostic value in malignant pleural mesothelioma. Oncotarget. 2017 Apr 18; 8(16):26744-26754. PMID: 28460459.
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    87. Koczkowska M, Lipska-Zietkiewicz BS, Iliszko M, Rys J, Miettinen M, Lasota J, Biernat W, Harazin-Lechowska A, Kruczak A, Limon J. Application of high-resolution genomic profiling in the differential diagnosis of liposarcoma. Mol Cytogenet. 2017; 10:7. PMID: 28331547.
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    88. Levy AD, Manning MA, Al-Refaie WB, Miettinen MM. Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 1-Common Sarcomas: From the Radiologic Pathology Archives. Radiographics. 2017 Mar-Apr; 37(2):462-483. PMID: 28287938.
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    89. Pandey PR, Chatterjee B, Olanich ME, Khan J, Miettinen MM, Hewitt SM, Barr FG. PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma. J Pathol. 2017 04; 241(5):626-637. PMID: 28138962.
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    90. Lasota J, Kowalik A, Felisiak-Golabek A, Inaguma S, Wang ZF, Pieciak L, Zieba S, Peksa R, Kopczynski J, Okon K, Waloszczyk P, Gozdz S, Biernat W, Miettinen M. SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts With KRAS Q61R Mutant Protein in Colorectal Carcinoma. Arch Pathol Lab Med. 2017 Apr; 141(4):564-568. PMID: 28353383.
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    91. Miettinen M, Felisiak-Golabek A, Wasag B, Chmara M, Wang Z, Butzow R, Lasota J. Fumarase-deficient Uterine Leiomyomas: An Immunohistochemical, Molecular Genetic, and Clinicopathologic Study of 86 Cases. Am J Surg Pathol. 2016 12; 40(12):1661-1669. PMID: 27454940.
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    92. Inaguma S, Lasota J, Wang Z, Felisiak-Golabek A, Ikeda H, Miettinen M. Clinicopathologic profile, immunophenotype, and genotype of CD274 (PD-L1)-positive colorectal carcinomas. Mod Pathol. 2017 02; 30(2):278-285. PMID: 27813511.
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    93. Thomas A, Chen Y, Berman A, Schrump DS, Giaccone G, Pastan I, Venzon DJ, Liewehr DJ, Steinberg SM, Miettinen M, Hassan R, Rajan A. Expression of mesothelin in thymic carcinoma and its potential therapeutic significance. Lung Cancer. 2016 11; 101:104-110. PMID: 27794397.
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    94. Zhang J, Khanna S, Jiang Q, Alewine C, Miettinen M, Pastan I, Hassan R. Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response. Clin Cancer Res. 2017 Mar 15; 23(6):1564-1574. PMID: 27635089.
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    95. Inaguma S, Wang Z, Lasota JP, Miettinen MM. Expression of neural cell adhesion molecule L1 (CD171) in neuroectodermal and other tumors: An immunohistochemical study of 5155 tumors and critical evaluation of CD171 prognostic value in gastrointestinal stromal tumors. Oncotarget. 2016 08 23; 7(34):55276-55289. PMID: 27419370.
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    96. Inaguma S, Wang Z, Lasota J, Sarlomo-Rikala M, McCue PA, Ikeda H, Miettinen M. Comprehensive Immunohistochemical Study of Programmed Cell Death Ligand 1 (PD-L1): Analysis in 5536 Cases Revealed Consistent Expression in Trophoblastic Tumors. Am J Surg Pathol. 2016 08; 40(8):1133-42. PMID: 27158757.
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    97. Boikos SA, Pappo AS, Killian JK, LaQuaglia MP, Weldon CB, George S, Trent JC, von Mehren M, Wright JA, Schiffman JD, Raygada M, Pacak K, Meltzer PS, Miettinen MM, Stratakis C, Janeway KA, Helman LJ. Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic. JAMA Oncol. 2016 Jul 01; 2(7):922-8. PMID: 27011036.
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    98. Kerkar SP, Wang ZF, Lasota J, Park T, Patel K, Groh E, Rosenberg SA, Miettinen MM. MAGE-A is More Highly Expressed Than NY-ESO-1 in a Systematic Immunohistochemical Analysis of 3668 Cases. J Immunother. 2016 May; 39(4):181-7. PMID: 27070449.
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    99. Kopczynski J, Kowalik A, Chlopek M, Wang ZF, G?zdz S, Lasota J, Miettinen M. Oncogenic Activation of the Wnt/?-Catenin Signaling Pathway in Signet Ring Stromal Cell Tumor of the Ovary. Appl Immunohistochem Mol Morphol. 2016 May-Jun; 24(5):e28-33. PMID: 26509912.
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    100. Cowen EW, Pichard DC, Garabedian E, Miettinen M. Medallion-Like Dermal Dendrocytic Hamartoma, Dermatofibrosarcoma Protuberans, and Adenosine Deaminase-Deficient Severe Combined Immunodeficiency. Pediatr Dermatol. 2016 May; 33(3):359-60. PMID: 27176810.
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    101. Chang W, Brohl AS, Patidar R, Sindiri S, Shern JF, Wei JS, Song YK, Yohe ME, Gryder B, Zhang S, Calzone KA, Shivaprasad N, Wen X, Badgett TC, Miettinen M, Hartman KR, League-Pascual JC, Trahair TN, Widemann BC, Merchant MS, Kaplan RN, Lin JC, Khan J. MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research. Clin Cancer Res. 2016 08 01; 22(15):3810-20. PMID: 26994145.
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    102. Montgomery BK, Alimchandani M, Mehta GU, Dewan R, Nesvick CL, Miettinen M, Heiss JD, Asthagiri AR, Quezado M, Germanwala AV. Tumors displaying hybrid schwannoma and neurofibroma features in patients with neurofibromatosis type 2. Clin Neuropathol. 2016 Mar-Apr; 35(2):78-83. PMID: 26709712.
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    103. Lasota J, Felisiak-Golabek A, Wasag B, Kowalik A, Zieba S, Chlopek M, Wang ZF, Coates T, Kopczynski J, Gozdz S, Sarlomo-Rikala M, Miettinen M. Frequency and clinicopathologic profile of PIK3CA mutant GISTs: molecular genetic study of 529 cases. Mod Pathol. 2016 Mar; 29(3):275-82. PMID: 26796526.
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    104. Rao M, Atay SM, Shukla V, Hong Y, Upham T, Ripley RT, Hong JA, Zhang M, Reardon E, Fetsch P, Miettinen M, Li X, Peer CJ, Sissung T, Figg WD, De Rienzo A, Bueno R, Schrump DS. Mithramycin Depletes Specificity Protein 1 and Activates p53 to Mediate Senescence and Apoptosis of Malignant Pleural Mesothelioma Cells. Clin Cancer Res. 2016 Mar 01; 22(5):1197-210. PMID: 26459178.
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    105. Miettinen M, Wang Z, Lasota J, Heery C, Schlom J, Palena C. Nuclear Brachyury Expression Is Consistent in Chordoma, Common in Germ Cell Tumors and Small Cell Carcinomas, and Rare in Other Carcinomas and Sarcomas: An Immunohistochemical Study of 5229 Cases. Am J Surg Pathol. 2015 Oct; 39(10):1305-12. PMID: 26099010.
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    106. Boikos SA, Xekouki P, Fumagalli E, Faucz FR, Raygada M, Szarek E, Ball E, Kim SY, Miettinen M, Helman LJ, Carney JA, Pacak K, Stratakis CA. Carney triad can be (rarely) associated with germline succinate dehydrogenase defects. Eur J Hum Genet. 2016 Apr; 24(4):569-73. PMID: 26173966.
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    107. Miettinen M, McCue PA, Sarlomo-Rikala M, Biernat W, Czapiewski P, Kopczynski J, Thompson LD, Lasota J, Wang Z, Fetsch JF. Sox10--a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors. Am J Surg Pathol. 2015 Jun; 39(6):826-35. PMID: 25724000.
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    108. Thomas A, Chen Y, Steinberg SM, Luo J, Pack S, Raffeld M, Abdullaev Z, Alewine C, Rajan A, Giaccone G, Pastan I, Miettinen M, Hassan R. High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis. Oncotarget. 2015 May 10; 6(13):11694-703. PMID: 26028668.
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    109. Kalra N, Zhang J, Thomas A, Xi L, Cheung M, Talarchek J, Burkett S, Tsokos MG, Chen Y, Raffeld M, Miettinen M, Pastan I, Testa JR, Hassan R. Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma. BMC Cancer. 2015 May 08; 15:376. PMID: 25952750.
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    110. Liu-Chittenden Y, Jain M, Kumar P, Patel D, Aufforth R, Neychev V, Sadowski S, Gara SK, Joshi BH, Cottle-Delisle C, Merkel R, Yang L, Miettinen M, Puri RK, Kebebew E. Phase I trial of systemic intravenous infusion of interleukin-13-Pseudomonas exotoxin in patients with metastatic adrenocortical carcinoma. Cancer Med. 2015 Jul; 4(7):1060-8. PMID: 25767039.
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    111. Laskin WB, Lasota JP, Fetsch JF, Felisiak-Golabek A, Wang ZF, Miettinen M. Intranodal palisaded myofibroblastoma: another mesenchymal neoplasm with CTNNB1 (?-catenin gene) mutations: clinicopathologic, immunohistochemical, and molecular genetic study of 18 cases. Am J Surg Pathol. 2015 Feb; 39(2):197-205. PMID: 25025452.
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    112. Miettinen M. [Succinate dehydrogenase-deficient tumors--a novel mechanism of tumor formation]. Duodecim. 2015; 131(22):2149-56. PMID: 26749909.
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    113. Killian JK, Miettinen M, Walker RL, Wang Y, Zhu YJ, Waterfall JJ, Noyes N, Retnakumar P, Yang Z, Smith WI, Killian MS, Lau CC, Pineda M, Walling J, Stevenson H, Smith C, Wang Z, Lasota J, Kim SY, Boikos SA, Helman LJ, Meltzer PS. Recurrent epimutation of SDHC in gastrointestinal stromal tumors. Sci Transl Med. 2014 Dec 24; 6(268):268ra177. PMID: 25540324.
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    114. Solomon DA, Brohl AS, Khan J, Miettinen M. Clinicopathologic features of a second patient with Ewing-like sarcoma harboring CIC-FOXO4 gene fusion. Am J Surg Pathol. 2014 Dec; 38(12):1724-5. PMID: 25321332.
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    115. Gill AJ, Hes O, Papathomas T, ?edivcov? M, Tan PH, Agaimy A, Andresen PA, Kedziora A, Clarkson A, Toon CW, Sioson L, Watson N, Chou A, Paik J, Clifton-Bligh RJ, Robinson BG, Benn DE, Hills K, Maclean F, Niemeijer ND, Vlatkovic L, Hartmann A, Corssmit EP, van Leenders GJ, Przybycin C, McKenney JK, Magi-Galluzzi C, Yilmaz A, Yu D, Nicoll KD, Yong JL, Sibony M, Yakirevich E, Fleming S, Chow CW, Miettinen M, Michal M, Trpkov K. Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients. Am J Surg Pathol. 2014 Dec; 38(12):1588-602. PMID: 25025441.
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    116. Lasota J, Felisiak-Golabek A, Aly FZ, Wang ZF, Thompson LD, Miettinen M. Nuclear expression and gain-of-function ?-catenin mutation in glomangiopericytoma (sinonasal-type hemangiopericytoma): insight into pathogenesis and a diagnostic marker. Mod Pathol. 2015 May; 28(5):715-20. PMID: 25431235.
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    117. Miller AC, Miettinen M, Schrump DS, Hassan R. Malignant mesothelioma and central nervous system metastases. Report of two cases, pooled analysis, and systematic review. Ann Am Thorac Soc. 2014 Sep; 11(7):1075-81. PMID: 25079105.
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    118. Lasota J, Kowalik A, Wasag B, Wang ZF, Felisiak-Golabek A, Coates T, Kopczynski J, Gozdz S, Miettinen M. Detection of the BRAF V600E mutation in colon carcinoma: critical evaluation of the imunohistochemical approach. Am J Surg Pathol. 2014 Sep; 38(9):1235-41. PMID: 24832158.
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    119. Thompson LD, Bauer JL, Chiosea S, McHugh JB, Seethala RR, Miettinen M, M?ller S. Canalicular adenoma: a clinicopathologic and immunohistochemical analysis of 67 cases with a review of the literature. Head Neck Pathol. 2015 Jun; 9(2):181-95. PMID: 25141970.
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    120. Brohl AS, Solomon DA, Chang W, Wang J, Song Y, Sindiri S, Patidar R, Hurd L, Chen L, Shern JF, Liao H, Wen X, Gerard J, Kim JS, Lopez Guerrero JA, Machado I, Wai DH, Picci P, Triche T, Horvai AE, Miettinen M, Wei JS, Catchpool D, Llombart-Bosch A, Waldman T, Khan J. The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation. PLoS Genet. 2014 Jul; 10(7):e1004475. PMID: 25010205.
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    121. Hassan R, Sharon E, Thomas A, Zhang J, Ling A, Miettinen M, Kreitman RJ, Steinberg SM, Hollevoet K, Pastan I. Phase 1 study of the antimesothelin immunotoxin SS1P in combination with pemetrexed and cisplatin for front-line therapy of pleural mesothelioma and correlation of tumor response with serum mesothelin, megakaryocyte potentiating factor, and cancer antigen 125. Cancer. 2014 Nov 01; 120(21):3311-9. PMID: 24989332.
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    122. Limon J, Miettinen M, Lasota J. Rare cancers. Int J Biochem Cell Biol. 2014 Aug; 53:461. PMID: 24907398.
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    123. Miettinen M, Lasota J. Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review. Int J Biochem Cell Biol. 2014 Aug; 53:514-9. PMID: 24886695.
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    124. Alimchandani M, Wang ZF, Miettinen M. CD30 expression in malignant vascular tumors and its diagnostic and clinical implications: a study of 146 cases. Appl Immunohistochem Mol Morphol. 2014 May-Jun; 22(5):358-62. PMID: 24805132.
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    125. Thomas A, Lee JH, Abdullaev Z, Park KS, Pineda M, Saidkhodjaeva L, Miettinen M, Wang Y, Pack SD, Giaccone G. Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer. J Thorac Oncol. 2014 Apr; 9(4):567-71. PMID: 24736083.
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    126. Miettinen M, Wang Z, McCue PA, Sarlomo-Rikala M, Rys J, Biernat W, Lasota J, Lee YS. SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 2014 Mar; 38(3):410-20. PMID: 24525512.
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    127. Mardekian SK, Gandhe A, Miettinen M, Pack S, Curtis MT, Abdullaev Z. Two Cases of Spinal, Extraosseous, Intradural Ewing's sarcoma/Peripheral Neuroectodermal Tumor: Radiologic, Pathologic, and Molecular Analysis. J Clin Imaging Sci. 2014; 4:6. PMID: 24678438.
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    128. Miettinen M, McCue PA, Sarlomo-Rikala M, Rys J, Czapiewski P, Wazny K, Langfort R, Waloszczyk P, Biernat W, Lasota J, Wang Z. GATA3: a multispecific but potentially useful marker in surgical pathology: a systematic analysis of 2500 epithelial and nonepithelial tumors. Am J Surg Pathol. 2014 Jan; 38(1):13-22. PMID: 24145643.
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    129. Miettinen M. Smooth muscle tumors of soft tissue and non-uterine viscera: biology and prognosis. Mod Pathol. 2014 Jan; 27 Suppl 1:S17-29. PMID: 24384850.
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    130. Miettinen M, Sarlomo-Rikala M, McCue P, Czapiewski P, Langfort R, Waloszczyk P, Wazny K, Biernat W, Lasota J, Wang Z. Mapping of succinate dehydrogenase losses in 2258 epithelial neoplasms. Appl Immunohistochem Mol Morphol. 2014 Jan; 22(1):31-6. PMID: 23531856.
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    131. Laskin WB, Fetsch JF, Miettinen M. Myxoinflammatory fibroblastic sarcoma: a clinicopathologic analysis of 104 cases, with emphasis on predictors of outcome. Am J Surg Pathol. 2014 Jan; 38(1):1-12. PMID: 24121178.
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    132. Miettinen M. Immunohistochemistry of soft tissue tumours - review with emphasis on 10 markers. Histopathology. 2014 Jan; 64(1):101-18. PMID: 24111893.
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    133. Hassan R, Miller AC, Sharon E, Thomas A, Reynolds JC, Ling A, Kreitman RJ, Miettinen MM, Steinberg SM, Fowler DH, Pastan I. Major cancer regressions in mesothelioma after treatment with an anti-mesothelin immunotoxin and immune suppression. Sci Transl Med. 2013 Oct 23; 5(208):208ra147. PMID: 24154601.
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    134. Solomon DA, Kim JS, Bondaruk J, Shariat SF, Wang ZF, Elkahloun AG, Ozawa T, Gerard J, Zhuang D, Zhang S, Navai N, Siefker-Radtke A, Phillips JJ, Robinson BD, Rubin MA, Volkmer B, Hautmann R, K?fer R, Hogendoorn PC, Netto G, Theodorescu D, James CD, Czerniak B, Miettinen M, Waldman T. Frequent truncating mutations of STAG2 in bladder cancer. Nat Genet. 2013 Dec; 45(12):1428-30. PMID: 24121789.
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    135. Miettinen M, Wang Z, Sarlomo-Rikala M, Abdullaev Z, Pack SD, Fetsch JF. ERG expression in epithelioid sarcoma: a diagnostic pitfall. Am J Surg Pathol. 2013 Oct; 37(10):1580-5. PMID: 23774169.
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    136. Spencer KR, Miettinen MM, Maki RG, Mehnert JM. When Benign Tumors Mimic Malignancies: A Case of Lymphangiomatosis Masquerading as Metastatic Disease. Rare Cancers Ther. 2013; 1:21-27. PMID: 27182474.
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    137. Thompson LD, Penner C, Ho NJ, Foss RD, Miettinen M, Wieneke JA, Moskaluk CA, Stelow EB. Sinonasal tract and nasopharyngeal adenoid cystic carcinoma: a clinicopathologic and immunophenotypic study of 86 cases. Head Neck Pathol. 2014 Mar; 8(1):88-109. PMID: 24037641.
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    138. Alimchandani M, Lai JP, Aung PP, Khangura S, Kamal N, Gallin JI, Holland SM, Malech HL, Heller T, Miettinen M, Quezado MM. Gastrointestinal histopathology in chronic granulomatous disease: a study of 87 patients. Am J Surg Pathol. 2013 Sep; 37(9):1365-72. PMID: 23887163.
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    139. Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger PC, Eberhart CG, Rodriguez FJ, Raabe E, Nazarian J, Warren K, Quezado MM. Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas. Am J Surg Pathol. 2013 Sep; 37(9):1357-64. PMID: 24076776.
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    140. Lasota J, Xi L, Coates T, Dennis R, Evbuomwan MO, Wang ZF, Raffeld M, Miettinen M. No KRAS mutations found in gastrointestinal stromal tumors (GISTs): molecular genetic study of 514 cases. Mod Pathol. 2013 Nov; 26(11):1488-91. PMID: 23702733.
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    141. Kelly L, Bryan K, Kim SY, Janeway KA, Killian JK, Schildhaus HU, Miettinen M, Helman L, Meltzer PS, van de Rijn M, Debiec-Rychter M, O'Sullivan M. Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]. PLoS One. 2013; 8(5):e64102. PMID: 23717541.
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    142. Killian JK, Kim SY, Miettinen M, Smith C, Merino M, Tsokos M, Quezado M, Smith WI, Jahromi MS, Xekouki P, Szarek E, Walker RL, Lasota J, Raffeld M, Klotzle B, Wang Z, Jones L, Zhu Y, Wang Y, Waterfall JJ, O'Sullivan MJ, Bibikova M, Pacak K, Stratakis C, Janeway KA, Schiffman JD, Fan JB, Helman L, Meltzer PS. Succinate dehydrogenase mutation underlies global epigenomic divergence in gastrointestinal stromal tumor. Cancer Discov. 2013 Jun; 3(6):648-57. PMID: 23550148.
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    143. Miettinen M, Lasota J. Gastrointestinal stromal tumors. Gastroenterol Clin North Am. 2013 Jun; 42(2):399-415. PMID: 23639648.
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    144. Miettinen M, Killian JK, Wang ZF, Lasota J, Lau C, Jones L, Walker R, Pineda M, Zhu YJ, Kim SY, Helman L, Meltzer P. Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation. Am J Surg Pathol. 2013 Feb; 37(2):234-40. PMID: 23282968.
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    145. Lasota J, Wang Z, Kim SY, Helman L, Miettinen M. Expression of the receptor for type i insulin-like growth factor (IGF1R) in gastrointestinal stromal tumors: an immunohistochemical study of 1078 cases with diagnostic and therapeutic implications. Am J Surg Pathol. 2013 Jan; 37(1):114-9. PMID: 22892600.
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    146. Lai JP, Rosenberg AZ, Miettinen MM, Lee CC. NY-ESO-1 expression in sarcomas: A diagnostic marker and immunotherapy target. Oncoimmunology. 2012 Nov 01; 1(8):1409-1410. PMID: 23243610.
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    147. Barak S, Wang Z, Miettinen M. Immunoreactivity for calretinin and keratins in desmoid fibromatosis and other myofibroblastic tumors: a diagnostic pitfall. Am J Surg Pathol. 2012 Sep; 36(9):1404-9. PMID: 22531174.
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    148. Miettinen M. A simple method for generating multitissue blocks without special equipment. Appl Immunohistochem Mol Morphol. 2012 Jul; 20(4):410-2. PMID: 22495380.
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    149. Stockman DL, Miettinen M, Suster S, Spagnolo D, Dominguez-Malagon H, Hornick JL, Adsay V, Chou PM, Amanuel B, Vantuinen P, Zambrano EV. Malignant gastrointestinal neuroectodermal tumor: clinicopathologic, immunohistochemical, ultrastructural, and molecular analysis of 16 cases with a reappraisal of clear cell sarcoma-like tumors of the gastrointestinal tract. Am J Surg Pathol. 2012 Jun; 36(6):857-68. PMID: 22592145.
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    150. Miettinen M, Rikala MS, Rys J, Lasota J, Wang ZF. Vascular endothelial growth factor receptor 2 as a marker for malignant vascular tumors and mesothelioma: an immunohistochemical study of 262 vascular endothelial and 1640 nonvascular tumors. Am J Surg Pathol. 2012 Apr; 36(4):629-39. PMID: 22314185.
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    151. Lai JP, Robbins PF, Raffeld M, Aung PP, Tsokos M, Rosenberg SA, Miettinen MM, Lee CC. NY-ESO-1 expression in synovial sarcoma and other mesenchymal tumors: significance for NY-ESO-1-based targeted therapy and differential diagnosis. Mod Pathol. 2012 Jun; 25(6):854-8. PMID: 22388761.
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    152. Miettinen M, Wang ZF. Prox1 transcription factor as a marker for vascular tumors-evaluation of 314 vascular endothelial and 1086 nonvascular tumors. Am J Surg Pathol. 2012 Mar; 36(3):351-9. PMID: 22067331.
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    153. Aung PP, Sarlomo-Rikala M, Lasota J, Lai JP, Wang ZF, Miettinen M. KBA62 and PNL2: 2 new melanoma markers-immunohistochemical analysis of 1563 tumors including metastatic, desmoplastic, and mucosal melanomas and their mimics. Am J Surg Pathol. 2012 Feb; 36(2):265-72. PMID: 22067329.
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    154. Miettinen M. [Gastrointestinal stromal tumor]. Duodecim. 2012; 128(14):1441-50. PMID: 22937603.
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    155. Miettinen M, Lasota J. Histopathology of gastrointestinal stromal tumor. J Surg Oncol. 2011 Dec; 104(8):865-73. PMID: 22069171.
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    156. Voltaggio L, Murray R, Lasota J, Miettinen M. Gastric schwannoma: a clinicopathologic study of 51 cases and critical review of the literature. Hum Pathol. 2012 May; 43(5):650-9. PMID: 22137423.
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    157. Miettinen M, Sarlomo-Rikala M, Wang ZF. Claudin-5 as an immunohistochemical marker for angiosarcoma and hemangioendotheliomas. Am J Surg Pathol. 2011 Dec; 35(12):1848-56. PMID: 21959309.
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    158. Miettinen M, Wang ZF, Sarlomo-Rikala M, Osuch C, Rutkowski P, Lasota J. Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age. Am J Surg Pathol. 2011 Nov; 35(11):1712-21. PMID: 21997692.
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    159. Patil DT, Laskin WB, Fetsch JF, Miettinen M. Inguinal smooth muscle tumors in women-a dichotomous group consisting of M?llerian-type leiomyomas and soft tissue leiomyosarcomas: an analysis of 55 cases. Am J Surg Pathol. 2011 Mar; 35(3):315-24. PMID: 21297441.
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    160. Miettinen M, Wang ZF, Paetau A, Tan SH, Dobi A, Srivastava S, Sesterhenn I. ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma. Am J Surg Pathol. 2011 Mar; 35(3):432-41. PMID: 21317715.
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    161. Liang Q, Wei M, Hodge L, Fanburg-Smith JC, Nelson A, Miettinen M, Foss RD, Wang G. Quantitative analysis of activating alpha subunit of the G protein (Gsa) mutation by pyrosequencing in fibrous dysplasia and other bone lesions. J Mol Diagn. 2011 Mar; 13(2):137-42. PMID: 21354047.
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    162. Wang JH, Lasota J, Miettinen M. Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists. J Cancer. 2011 Feb 16; 2:90-3. PMID: 21479127.
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    163. Pelz AF, Agaimy A, Daniels M, Evert M, Schulz HU, L?ders P, M?ller G, Lasota J, R?pke A, Wieacker P, Miettinen M, Schneider-Stock R. Gastrointestinal stromal tumor presenting as a rectovaginal mass. Clinicopathologic and molecular-genetic characterization of a rare tumor with a literature review. Hum Pathol. 2011 Apr; 42(4):586-93. PMID: 21237497.
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    164. Deyrup AT, Miettinen M, North PE, Khoury JD, Tighiouart M, Spunt SL, Parham DM, Shehata BM, Weiss SW. Pediatric cutaneous angiosarcomas: a clinicopathologic study of 10 cases. Am J Surg Pathol. 2011 Jan; 35(1):70-5. PMID: 21164289.
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    165. Laskin WB, Fanburg-Smith JC, Burke AP, Kraszewska E, Fetsch JF, Miettinen M. Leiomyosarcoma of the inferior vena cava: clinicopathologic study of 40 cases. Am J Surg Pathol. 2010 Jun; 34(6):873-81. PMID: 20463568.
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    166. Kleist B, Lasota J, Miettinen M. Gastrointestinal stromal tumor and gastric adenocarcinoma collision tumors. Hum Pathol. 2010 Jul; 41(7):1034-9. PMID: 20381123.
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    167. Rubin BP, Blanke CD, Demetri GD, Dematteo RP, Fletcher CD, Goldblum JR, Lasota J, Lazar A, Maki RG, Miettinen M, Noffsinger A, Washington MK, Krausz T. Protocol for the examination of specimens from patients with gastrointestinal stromal tumor. Arch Pathol Lab Med. 2010 Feb; 134(2):165-70. PMID: 20121601.
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    168. Parkkila S, Lasota J, Fletcher JA, Ou WB, Kivel? AJ, Nuorva K, Parkkila AK, Ollikainen J, Sly WS, Waheed A, Pastorekova S, Pastorek J, Isola J, Miettinen M. Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors. Mod Pathol. 2010 May; 23(5):743-50. PMID: 20081808.
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    169. Miettinen M, Makhlouf HR, Sobin LH, Lasota J. Plexiform fibromyxoma: a distinctive benign gastric antral neoplasm not to be confused with a myxoid GIST. Am J Surg Pathol. 2009 Nov; 33(11):1624-32. PMID: 19675452.
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    170. Murphey MD, Ruble CM, Tyszko SM, Zbojniewicz AM, Potter BK, Miettinen M. From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 2009 Nov; 29(7):2143-73. PMID: 19926768.
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    171. Al-Daraji W, Lasota J, Foss R, Miettinen M. Synovial sarcoma involving the head: analysis of 36 cases with predilection to the parotid and temporal regions. Am J Surg Pathol. 2009 Oct; 33(10):1494-503. PMID: 19623036.
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    172. Miettinen M, Dow N, Lasota J, Sobin LH. A distinctive novel epitheliomesenchymal biphasic tumor of the stomach in young adults ("gastroblastoma"): a series of 3 cases. Am J Surg Pathol. 2009 Sep; 33(9):1370-7. PMID: 19718790.
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    173. Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors presenting as omental masses--a clinicopathologic analysis of 95 cases. Am J Surg Pathol. 2009 Sep; 33(9):1267-75. PMID: 19440146.
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    174. Miettinen M, Wang ZF, Lasota J. DOG1 antibody in the differential diagnosis of gastrointestinal stromal tumors: a study of 1840 cases. Am J Surg Pathol. 2009 Sep; 33(9):1401-8. PMID: 19606013.
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    175. Al-Daraji WI, Makhlouf HR, Miettinen M, Montgomery EA, Goodman ZD, Marwaha JS, Fanburg-Smith JC. Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. Am J Surg Pathol. 2009 Jun; 33(6):826-34. PMID: 19194282.
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    176. Lasota J, Wang ZF, Sobin LH, Miettinen M. Gain-of-function PDGFRA mutations, earlier reported in gastrointestinal stromal tumors, are common in small intestinal inflammatory fibroid polyps. A study of 60 cases. Mod Pathol. 2009 Aug; 22(8):1049-56. PMID: 19448595.
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    177. Miettinen M, Sobin LH, Lasota J. True smooth muscle tumors of the small intestine: a clinicopathologic, immunhistochemical, and molecular genetic study of 25 cases. Am J Surg Pathol. 2009 Mar; 33(3):430-6. PMID: 18971781.
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    178. Deyrup AT, Miettinen M, North PE, Khoury JD, Tighiouart M, Spunt SL, Parham D, Weiss SW, Shehata BM. Angiosarcomas arising in the viscera and soft tissue of children and young adults: a clinicopathologic study of 15 cases. Am J Surg Pathol. 2009 Feb; 33(2):264-9. PMID: 18987547.
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    179. Laskin WB, Miettinen M, Fetsch JF. Infantile digital fibroma/fibromatosis: a clinicopathologic and immunohistochemical study of 69 tumors from 57 patients with long-term follow-up. Am J Surg Pathol. 2009 Jan; 33(1):1-13. PMID: 18830128.
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    180. Tavora F, Miettinen M, Fanburg-Smith J, Franks TJ, Burke A. Pulmonary artery sarcoma: a histologic and follow-up study with emphasis on a subset of low-grade myofibroblastic sarcomas with a good long-term follow-up. Am J Surg Pathol. 2008 Dec; 32(12):1751-61. PMID: 18779732.
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    181. Lasota J, Kuban W, Wardelmann E, Debiec-Rychter M, Merkelbach-Bruse S, Sciot R, Rys J, Steigen SE, Iwanik K, Holden JA, Jerzak Vel Dobosz A, Schildhaus HU, Miettinen M. KIT codon 558 insertions in gastrointestinal stromal tumors. Analysis of 17 rare KIT mutants. Hum Pathol. 2008 Dec; 39(12):1728-36. PMID: 18715619.
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    182. Miettinen M, Finnell V, Fetsch JF. Ossifying fibromyxoid tumor of soft parts--a clinicopathologic and immunohistochemical study of 104 cases with long-term follow-up and a critical review of the literature. Am J Surg Pathol. 2008 Jul; 32(7):996-1005. PMID: 18469710.
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    183. Al-Daraji WI, Miettinen M. Superficial acral fibromyxoma: a clinicopathological analysis of 32 tumors including 4 in the heel. J Cutan Pathol. 2008 Nov; 35(11):1020-6. PMID: 18537858.
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    184. Paul SR, Hurford MT, Miettinen MM, Aronoff SC, Delvecchio M, Grewal H, Tuluc M. Polymorphous hemangioendothelioma in a child with acquired immunodeficiency syndrome (AIDS). Pediatr Blood Cancer. 2008 Mar; 50(3):663-5. PMID: 16991137.
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    185. Miettinen M, Kraszewska E, Sobin LH, Lasota J. A nonrandom association between gastrointestinal stromal tumors and myeloid leukemia. Cancer. 2008 Feb 01; 112(3):645-9. PMID: 18041070.
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    186. Lasota J, Corless CL, Heinrich MC, Debiec-Rychter M, Sciot R, Wardelmann E, Merkelbach-Bruse S, Schildhaus HU, Steigen SE, Stachura J, Wozniak A, Antonescu C, Daum O, Martin J, Del Muro JG, Miettinen M. Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases. Mod Pathol. 2008 Apr; 21(4):476-84. PMID: 18246046.
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    187. Makhlouf HR, Ahrens W, Agarwal B, Dow N, Marshalleck JJ, Lee EL, Dotto JE, Hui P, Sobin LH, Oliveira A, Miettinen M. Synovial sarcoma of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 10 cases. Am J Surg Pathol. 2008 Feb; 32(2):275-81. PMID: 18223331.
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    188. Lasota J, vel Dobosz AJ, Wasag B, Wozniak A, Kraszewska E, Michej W, Ptaszynski K, Rutkowski P, Sarlomo-Rikala M, Steigen SE, Schneider-Stock R, Stachura J, Chosia M, Ogun G, Ruka W, Siedlecki JA, Miettinen M. Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors. Lab Invest. 2007 Oct; 87(10):1029-41. PMID: 17632543.
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    189. Fetsch JF, Laskin WB, Hallman JR, Lupton GP, Miettinen M. Neurothekeoma: an analysis of 178 tumors with detailed immunohistochemical data and long-term patient follow-up information. Am J Surg Pathol. 2007 Jul; 31(7):1103-14. PMID: 17592278.
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    190. Burke A, Li L, Kling E, Kutys R, Virmani R, Miettinen M. Cardiac inflammatory myofibroblastic tumor: a "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death. Am J Surg Pathol. 2007 Jul; 31(7):1115-22. PMID: 17592279.
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    191. Ass?m?ki R, Sarlomo-Rikala M, Lopez-Guerrero JA, Lasota J, Andersson LC, Llombart-Bosch A, Miettinen M, Knuutila S. Array comparative genomic hybridization analysis of chromosomal imbalances and their target genes in gastrointestinal stromal tumors. Genes Chromosomes Cancer. 2007 Jun; 46(6):564-76. PMID: 17330260.
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    192. Lasota J, Miettinen M. KIT exon 11 deletion-inversions represent complex mutations in gastrointestinal stromal tumors. Cancer Genet Cytogenet. 2007 May; 175(1):69-72. PMID: 17498562.
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    193. Steigen SE, Eide TJ, Wasag B, Lasota J, Miettinen M. Mutations in gastrointestinal stromal tumors--a population-based study from Northern Norway. APMIS. 2007 Apr; 115(4):289-98. PMID: 17504295.
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    194. Lasota J, Wasag B, Steigen SE, Limon J, Miettinen M. Improved detection of KIT exon 11 duplications in formalin-fixed, paraffin-embedded gastrointestinal stromal tumors. J Mol Diagn. 2007 Feb; 9(1):89-94. PMID: 17251340.
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    195. Laskin WB, Miettinen M, Fetsch JF. Calcareous lesions of the distal extremities resembling tumoral calcinosis (tumoral calcinosislike lesions): clinicopathologic study of 43 cases emphasizing a pathogenesis-based approach to classification. Am J Surg Pathol. 2007 Jan; 31(1):15-25. PMID: 17197915.
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    196. Shilo K, Miettinen M, Travis WD, Timens W, Nogueira R, Franks TJ. Pulmonary microcystic fibromyxoma: Report of 3 cases. Am J Surg Pathol. 2006 Nov; 30(11):1432-5. PMID: 17063085.
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    197. Turaga KK, Silva-Lopez E, Sanger WG, Nelson M, Hunter WJ, Miettinen M, Gatalica Z. A (9;11)(q34;q13) translocation in a hibernoma. Cancer Genet Cytogenet. 2006 Oct 15; 170(2):163-6. PMID: 17011989.
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    198. Miettinen M, Lasota J. Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med. 2006 Oct; 130(10):1466-78. PMID: 17090188.
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    199. Lasota J, Miettinen M. A new familial GIST identified. Am J Surg Pathol. 2006 Oct; 30(10):1342. PMID: 17001171.
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    200. Laskin WB, Fetsch JF, Michal M, Miettinen M. Sclerotic (fibroma-like) lipoma: a distinctive lipoma variant with a predilection for the distal extremities. Am J Dermatopathol. 2006 Aug; 28(4):308-16. PMID: 16871033.
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    201. Michal M, Fanburg-Smith JC, Lasota J, Fetsch JF, Lichy J, Miettinen M. Minute synovial sarcomas of the hands and feet: a clinicopathologic study of 21 tumors less than 1 cm. Am J Surg Pathol. 2006 Jun; 30(6):721-6. PMID: 16723849.
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    202. Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol. 2006 May; 23(2):70-83. PMID: 17193820.
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    203. Agaimy A, W?nsch PH, Sobin LH, Lasota J, Miettinen M. Occurrence of other malignancies in patients with gastrointestinal stromal tumors. Semin Diagn Pathol. 2006 May; 23(2):120-9. PMID: 17193825.
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    204. Lasota J, Miettinen M. KIT and PDGFRA mutations in gastrointestinal stromal tumors (GISTs). Semin Diagn Pathol. 2006 May; 23(2):91-102. PMID: 17193822.
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    205. Dow N, Giblen G, Sobin LH, Miettinen M. Gastrointestinal stromal tumors: differential diagnosis. Semin Diagn Pathol. 2006 May; 23(2):111-9. PMID: 17193824.
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    206. Miettinen M, Fetsch JF. Reticulohistiocytoma (solitary epithelioid histiocytoma): a clinicopathologic and immunohistochemical study of 44 cases. Am J Surg Pathol. 2006 Apr; 30(4):521-8. PMID: 16625100.
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    207. Miettinen M, Makhlouf H, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the jejunum and ileum: a clinicopathologic, immunohistochemical, and molecular genetic study of 906 cases before imatinib with long-term follow-up. Am J Surg Pathol. 2006 Apr; 30(4):477-89. PMID: 16625094.
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    208. Lasota J, Stachura J, Miettinen M. GISTs with PDGFRA exon 14 mutations represent subset of clinically favorable gastric tumors with epithelioid morphology. Lab Invest. 2006 Jan; 86(1):94-100. PMID: 16258521.
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    209. Miettinen M, Fetsch JF, Sobin LH, Lasota J. Gastrointestinal stromal tumors in patients with neurofibromatosis 1: a clinicopathologic and molecular genetic study of 45 cases. Am J Surg Pathol. 2006 Jan; 30(1):90-6. PMID: 16330947.
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    210. Miettinen M. From morphological to molecular diagnosis of soft tissue tumors. Adv Exp Med Biol. 2006; 587:99-113. PMID: 17163160.
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    211. Fanburg-Smith JC, Majidi M, Miettinen M. Keratin expression in schwannoma; a study of 115 retroperitoneal and 22 peripheral schwannomas. Mod Pathol. 2006 Jan; 19(1):115-21. PMID: 16357842.
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    212. Fetsch JF, Laskin WB, Miettinen M. Nerve sheath myxoma: a clinicopathologic and immunohistochemical analysis of 57 morphologically distinctive, S-100 protein- and GFAP-positive, myxoid peripheral nerve sheath tumors with a predilection for the extremities and a high local recurrence rate. Am J Surg Pathol. 2005 Dec; 29(12):1615-24. PMID: 16327434.
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    213. Miettinen M, Lasota J, Sobin LH. Gastrointestinal stromal tumors of the stomach in children and young adults: a clinicopathologic, immunohistochemical, and molecular genetic study of 44 cases with long-term follow-up and review of the literature. Am J Surg Pathol. 2005 Oct; 29(10):1373-81. PMID: 16160481.
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    214. Miettinen M, Lasota J. KIT (CD117): a review on expression in normal and neoplastic tissues, and mutations and their clinicopathologic correlation. Appl Immunohistochem Mol Morphol. 2005 Sep; 13(3):205-20. PMID: 16082245.
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    215. Fetsch JF, Laskin WB, Miettinen M. Palmar-plantar fibromatosis in children and preadolescents: a clinicopathologic study of 56 cases with newly recognized demographics and extended follow-up information. Am J Surg Pathol. 2005 Aug; 29(8):1095-105. PMID: 16006806.
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    216. Lassus P, Ristim?ki A, Huuhtanen R, Tukiainen E, Asko-Seljavaara S, Andersson LC, Miettinen M, Blomqvist C, Haglund C, B?hling T. Cyclooxygenase-2 expression in human soft-tissue sarcomas is related to epithelial differentation. Anticancer Res. 2005 Jul-Aug; 25(4):2669-74. PMID: 16080510.
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    217. Vos JA, Abbondanzo SL, Barekman CL, Andriko JW, Miettinen M, Aguilera NS. Histiocytic sarcoma: a study of five cases including the histiocyte marker CD163. Mod Pathol. 2005 May; 18(5):693-704. PMID: 15696128.
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    218. Levy AD, Patel N, Dow N, Abbott RM, Miettinen M, Sobin LH. From the archives of the AFIP: abdominal neoplasms in patients with neurofibromatosis type 1: radiologic-pathologic correlation. Radiographics. 2005 Mar-Apr; 25(2):455-80. PMID: 15798063.
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    219. Levy AD, Quiles AM, Miettinen M, Sobin LH. Gastrointestinal schwannomas: CT features with clinicopathologic correlation. AJR Am J Roentgenol. 2005 Mar; 184(3):797-802. PMID: 15728600.
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    220. Lasota J, Wozniak A, Kopczynski J, Dansonka-Mieszkowska A, Wasag B, Mitsuhashi T, Sarlomo-Rikala M, Lee JR, Schneider-Stock R, Stachura J, Limon J, Miettinen M. Loss of heterozygosity on chromosome 22q in gastrointestinal stromal tumors (GISTs): a study on 50 cases. Lab Invest. 2005 Feb; 85(2):237-47. PMID: 15580284.
      Citations:    
    221. Padula A, Chin NW, Azeez S, Resetkova E, Andriko JA, Miettinen M. Primary gastrointestinal stromal tumor of the esophagus in an HIV-positive patient. Ann Diagn Pathol. 2005 Feb; 9(1):49-53. PMID: 15692952.
      Citations:    
    222. Schneider-Stock R, Boltze C, Lasota J, Peters B, Corless CL, Ruemmele P, Terracciano L, Pross M, Insabato L, Di Vizio D, Iesalnieks I, Dirnhofer S, Hartmann A, Heinrich M, Miettinen M, Roessner A, Tornillo L. Loss of p16 protein defines high-risk patients with gastrointestinal stromal tumors: a tissue microarray study. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1):638-45. PMID: 15701851.
      Citations:    
    223. Laskin WB, Fetsch JF, Lasota J, Miettinen M. Benign epithelioid peripheral nerve sheath tumors of the soft tissues: clinicopathologic spectrum of 33 cases. Am J Surg Pathol. 2005 Jan; 29(1):39-51. PMID: 15613855.
      Citations:    
    224. Miettinen M, Sobin LH, Lasota J. Gastrointestinal stromal tumors of the stomach: a clinicopathologic, immunohistochemical, and molecular genetic study of 1765 cases with long-term follow-up. Am J Surg Pathol. 2005 Jan; 29(1):52-68. PMID: 15613856.
      Citations:    
    225. Levy AD, Patel N, Abbott RM, Dow N, Miettinen M, Sobin LH. Gastrointestinal stromal tumors in patients with neurofibromatosis: imaging features with clinicopathologic correlation. AJR Am J Roentgenol. 2004 Dec; 183(6):1629-36. PMID: 15547202.
      Citations:    
    226. Fetsch JF, Laskin WB, Michal M, Remotti F, Heffner D, Ellis G, Furlong M, Miettinen M. Ectopic hamartomatous thymoma: a clinicopathologic and immunohistochemical analysis of 21 cases with data supporting reclassification as a branchial anlage mixed tumor. Am J Surg Pathol. 2004 Oct; 28(10):1360-70. PMID: 15371953.
      Citations:    
    227. Lasota J, Dansonka-Mieszkowska A, Sobin LH, Miettinen M. A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential. Lab Invest. 2004 Jul; 84(7):874-83. PMID: 15146165.
      Citations:    
    228. Levy AD, Cantisani V, Miettinen M. Abdominal lymphangiomas: imaging features with pathologic correlation. AJR Am J Roentgenol. 2004 Jun; 182(6):1485-91. PMID: 15149994.
      Citations:    
    229. Fetsch JF, Sesterhenn IA, Miettinen M, Davis CJ. Epithelioid hemangioma of the penis: a clinicopathologic and immunohistochemical analysis of 19 cases, with special reference to exuberant examples often confused with epithelioid hemangioendothelioma and epithelioid angiosarcoma. Am J Surg Pathol. 2004 Apr; 28(4):523-33. PMID: 15087672.
      Citations:    
    230. Velagaleti GV, Miettinen M, Gatalica Z. Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant triton tumor) with balanced t(7;9)(q11.2;p24) and unbalanced translocation der(16)t(1;16)(q23;q13). Cancer Genet Cytogenet. 2004 Feb; 149(1):23-7. PMID: 15104279.
      Citations:    
    231. Folpe AL, Fanburg-Smith JC, Billings SD, Bisceglia M, Bertoni F, Cho JY, Econs MJ, Inwards CY, Jan de Beur SM, Mentzel T, Montgomery E, Michal M, Miettinen M, Mills SE, Reith JD, O'Connell JX, Rosenberg AE, Rubin BP, Sweet DE, Vinh TN, Wold LE, Wehrli BM, White KE, Zaino RJ, Weiss SW. Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature. Am J Surg Pathol. 2004 Jan; 28(1):1-30. PMID: 14707860.
      Citations:    
    232. Fetsch JF, Davis CJ, Miettinen M, Sesterhenn IA. Leiomyosarcoma of the penis: a clinicopathologic study of 14 cases with review of the literature and discussion of the differential diagnosis. Am J Surg Pathol. 2004 01; 28(1):115-25. PMID: 14707873.
      Citations:    
    233. Lasota J, Dansonka-Mieszkowska A, Stachura T, Schneider-Stock R, Kallajoki M, Steigen SE, Sarlomo-Rikala M, Boltze C, Kordek R, Roessner A, Stachura J, Miettinen M. Gastrointestinal stromal tumors with internal tandem duplications in 3' end of KIT juxtamembrane domain occur predominantly in stomach and generally seem to have a favorable course. Mod Pathol. 2003 Dec; 16(12):1257-64. PMID: 14681327.
      Citations:    
    234. Lasota J, Kopczynski J, Sarlomo-Rikala M, Schneider-Stock R, Stachura T, Kordek R, Michal M, Boltze C, Roessner A, Stachura J, Miettinen M. KIT 1530ins6 mutation defines a subset of predominantly malignant gastrointestinal stromal tumors of intestinal origin. Hum Pathol. 2003 Dec; 34(12):1306-12. PMID: 14691917.
      Citations:    
    235. Bratthauer GL, Miettinen M, Tavassoli FA. Cytokeratin immunoreactivity in lobular intraepithelial neoplasia. J Histochem Cytochem. 2003 Nov; 51(11):1527-31. PMID: 14566024.
      Citations:    
    236. Laskin WB, Miettinen M. Epithelioid sarcoma: new insights based on an extended immunohistochemical analysis. Arch Pathol Lab Med. 2003 Sep; 127(9):1161-8. PMID: 12946229.
      Citations:    
    237. Lasota J, Wasag B, Dansonka-Mieszkowska A, Karcz D, Millward CL, Rys J, Stachura J, Sobin LH, Miettinen M. Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas: s study of 20 cases. Lab Invest. 2003 Sep; 83(9):1361-71. PMID: 13679444.
      Citations:    
    238. Levy AD, Remotti HE, Thompson WM, Sobin LH, Miettinen M. Anorectal gastrointestinal stromal tumors: CT and MR imaging features with clinical and pathologic correlation. AJR Am J Roentgenol. 2003 Jun; 180(6):1607-12. PMID: 12760929.
      Citations:    
    239. Thompson LD, Miettinen M, Wenig BM. Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol. 2003 Jun; 27(6):737-49. PMID: 12766577.
      Citations:    
    240. Miettinen M, Kopczynski J, Makhlouf HR, Sarlomo-Rikala M, Gyorffy H, Burke A, Sobin LH, Lasota J. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the duodenum: a clinicopathologic, immunohistochemical, and molecular genetic study of 167 cases. Am J Surg Pathol. 2003 May; 27(5):625-41. PMID: 12717247.
      Citations:    
    241. Schneider-Stock R, Boltze C, Lasota J, Miettinen M, Peters B, Pross M, Roessner A, G?nther T. High prognostic value of p16INK4 alterations in gastrointestinal stromal tumors. J Clin Oncol. 2003 May 01; 21(9):1688-97. PMID: 12721243.
      Citations:    
    242. Thompson LD, Wieneke JA, Miettinen M. Sinonasal tract and nasopharyngeal melanomas: a clinicopathologic study of 115 cases with a proposed staging system. Am J Surg Pathol. 2003 May; 27(5):594-611. PMID: 12717245.
      Citations:    
    243. Levy AD, Remotti HE, Thompson WM, Sobin LH, Miettinen M. Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics. 2003 Mar-Apr; 23(2):283-304, 456; quiz 532. PMID: 12640147.
      Citations:    
    244. Velagaleti GV, Tapper JK, Panova NE, Miettinen M, Gatalica Z. Cytogenetic findings in a case of nodular fasciitis of subclavicular region. Cancer Genet Cytogenet. 2003 Mar; 141(2):160-3. PMID: 12606136.
      Citations:    
    245. Miettinen M, Sarlomo-Rikala M. Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleura. Am J Surg Pathol. 2003 Feb; 27(2):150-8. PMID: 12548160.
      Citations:    
    246. Miettinen M, Lasota J. Gastrointestinal stromal tumors (GISTs): definition, occurrence, pathology, differential diagnosis and molecular genetics. Pol J Pathol. 2003; 54(1):3-24. PMID: 12817876.
      Citations:    
    247. Miettinen M, Majidi M, Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review. Eur J Cancer. 2002 Sep; 38 Suppl 5:S39-51. PMID: 12528772.
      Citations:    
    248. Lasota J, Kopczynski J, Majidi M, Miettinen M, Sarlomo-Rikala M. Apparent KIT Ser(715) deletion in GIST mRNA is not detectable in genomic DNA and represents a previously known splice variant of KIT transcript. Am J Pathol. 2002 Aug; 161(2):739-41. PMID: 12163399.
      Citations:    
    249. Sarlomo-Rikala M, Tsujimura T, Lendahl U, Miettinen M. Patterns of nestin and other intermediate filament expression distinguish between gastrointestinal stromal tumors, leiomyomas and schwannomas. APMIS. 2002 Jun; 110(6):499-507. PMID: 12193211.
      Citations:    
    250. Miettinen M, Paetau A. Mapping of the keratin polypeptides in meningiomas of different types: an immunohistochemical analysis of 463 cases. Hum Pathol. 2002 Jun; 33(6):590-8. PMID: 12152157.
      Citations:    
    251. Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O'Leary TJ, Remotti H, Rubin BP, Shmookler B, Sobin LH, Weiss SW. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol. 2002 May; 33(5):459-65. PMID: 12094370.
      Citations:    
    252. Miettinen M, El-Rifai W, H L Sobin L, Lasota J. Evaluation of malignancy and prognosis of gastrointestinal stromal tumors: a review. Hum Pathol. 2002 May; 33(5):478-83. PMID: 12094372.
      Citations:    
    253. Laskin WB, Miettinen M. Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues. Arch Pathol Lab Med. 2002 Apr; 126(4):425-31. PMID: 11900566.
      Citations:    
    254. Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O'Leary TJ, Remotti H, Rubin BP, Shmookler B, Sobin LH, Weiss SW. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Int J Surg Pathol. 2002 Apr; 10(2):81-9. PMID: 12075401.
      Citations:    
    255. Miettinen M, Paal E, Lasota J, Sobin LH. Gastrointestinal glomus tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 32 cases. Am J Surg Pathol. 2002 Mar; 26(3):301-11. PMID: 11859201.
      Citations:    
    256. Thompson LD, Wieneke JA, Miettinen M, Heffner DK. Spindle cell (sarcomatoid) carcinomas of the larynx: a clinicopathologic study of 187 cases. Am J Surg Pathol. 2002 Feb; 26(2):153-70. PMID: 11812937.
      Citations:    
    257. Miettinen M. New challenges in the identification of gastrointestinal stromal tumors and other possible KIT-driven tumors. Am J Clin Pathol. 2002 Feb; 117(2):183-5. PMID: 11863213.
      Citations:    
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