RNA-Binding Protein FUS

"RNA-Binding Protein FUS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.

Descriptor ID	D034702
MeSH Number(s)	D12.776.157.725.813.750.905 D12.776.624.664.700.915 D12.776.664.962.813.750.902
Concept/Terms	RNA-Binding Protein FUS RNA-Binding Protein FUS RNA Binding Protein FUS TLS Protein POMp75 Protein Translocated in Liposarcoma Protein FUS RNA-Binding Protein FUS RNA Binding Protein RNA-Binding Protein, FUS Fusion Protein in Myxoid Liposarcoma FUS Protein hnRNP P2

Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein FUS".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
RNA-Binding Proteins [D12.776.157.725]
RNA Recognition Motif Proteins [D12.776.157.725.813]
Heterogeneous-Nuclear Ribonucleoproteins [D12.776.157.725.813.750]
RNA-Binding Protein FUS [D12.776.157.725.813.750.905]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
RNA-Binding Protein FUS [D12.776.624.664.700.915]
Nucleoproteins [D12.776.664]
RNA-Binding Proteins [D12.776.664.962]
RNA Recognition Motif Proteins [D12.776.664.962.813]
Heterogeneous-Nuclear Ribonucleoproteins [D12.776.664.962.813.750]
RNA-Binding Protein FUS [D12.776.664.962.813.750.902]

Below are MeSH descriptors whose meaning is related to "RNA-Binding Protein FUS".

Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein FUS".

publications

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This graph shows the total number of publications written about "RNA-Binding Protein FUS" by people in this website by year, and whether "RNA-Binding Protein FUS" was a major or minor topic of these publications.

Bar chart showing 5 publications over 4 distinct years, with a maximum of 2 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	0	1
2011	1	0	1
2012	1	0	1
2017	1	1	2

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