Allan Shaw

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address833 Chestnut Street
Philadelphia PA 19107
Phone215-640-0811
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Arag?n-Gonz?lez A, Shaw AC, Kok JR, Roussel FS, Santos Souza CD, Granger SM, Vetter T, de Diego Y, Meyer KC, Beal SN, Shaw PJ, Ferraiuolo L. C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity. Fluids Barriers CNS. 2024 Apr 11; 21(1):34. PMID: 38605366.
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    2. Harvey C, Weinreich M, Lee JAK, Shaw AC, Ferraiuolo L, Mortiboys H, Zhang S, Hop PJ, Zwamborn RAJ, van Eijk K, Julian TH, Moll T, Iacoangeli A, Al Khleifat A, Quinn JP, Pfaff AL, K?ks S, Poulton J, Battle SL, Arking DE, Snyder MP, Veldink JH, Kenna KP, Shaw PJ, Cooper-Knock J. Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis. Heliyon. 2024 Feb 15; 10(3):e24975. PMID: 38317984.
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    3. Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin YH, Smith EF, Illanes-?lvarez F, Higginbottom A, Shaw PJ, Azzouz M, Ferraiuolo L, Hautbergue GM, Grierson AJ, De Vos KJ. Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation. Front Cell Neurosci. 2022; 16:1061559. PMID: 36619668.
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    4. Marchi PM, Marrone L, Brasseur L, Coens A, Webster CP, Bousset L, Destro M, Smith EF, Walther CG, Alfred V, Marroccella R, Graves EJ, Robinson D, Shaw AC, Wan LM, Grierson AJ, Ebbens SJ, De Vos KJ, Hautbergue GM, Ferraiuolo L, Melki R, Azzouz M. C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons. Life Sci Alliance. 2022 09; 5(9). PMID: 35568435.
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    5. Gatto N, Dos Santos Souza C, Shaw AC, Bell SM, Myszczynska MA, Powers S, Meyer K, Castelli LM, Karyka E, Mortiboys H, Azzouz M, Hautbergue GM, M?rkus NM, Shaw PJ, Ferraiuolo L. Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease. Aging Cell. 2021 01; 20(1):e13281. PMID: 33314575.
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    6. Vernet E, Pedersen M?, Th?gersen H, Shaw AC. Engineering Xaa-Pro dipeptidyl aminopeptidase for specific cleavage of glucagon and glucagon-like peptide 1 from fusion proteins. Protein Expr Purif. 2020 06; 170:105590. PMID: 32007557.
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    7. Allen SP, Hall B, Woof R, Francis L, Gatto N, Shaw AC, Myszczynska M, Hemingway J, Coldicott I, Willcock A, Job L, Hughes RM, Boschian C, Bayatti N, Heath PR, Bandmann O, Mortiboys H, Ferraiuolo L, Shaw PJ. C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis. Brain. 2019 12 01; 142(12):3771-3790. PMID: 31647549.
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    8. Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, ?berg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Gr?nborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honor? C, Ahnfelt-R?nne J, Hecksher-S?rensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. The EndoC-?H1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates. Mol Metab. 2018 02; 8:144-157. PMID: 29307512.
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    9. Johansson E, Hansen JL, Hansen AM, Shaw AC, Becker P, Sch?ffer L, Reedtz-Runge S. Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography. J Biol Chem. 2016 Jun 24; 291(26):13689-98. PMID: 27189946.
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    10. Albertsen L, Shaw AC, Norrild JC, Str?mgaard K. Recombinant production of peptide C-terminal a-amides using an engineered intein. Bioconjug Chem. 2013 Nov 20; 24(11):1883-94. PMID: 24138202.
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    11. Kang L, Shaw AC, Xu D, Xia W, Zhang J, Deng J, W?ldike HF, Liu Y, Su J. Upregulation of MetC is essential for D-alanine-independent growth of an alr/dadX-deficient Escherichia coli strain. J Bacteriol. 2011 Mar; 193(5):1098-106. PMID: 21193606.
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    12. Andersen AS, Palmqvist E, Bang S, Shaw AC, Hubalek F, Ribel U, Hoeg-Jensen T. Backbone cyclic insulin. J Pept Sci. 2010 Sep; 16(9):473-9. PMID: 20641002.
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    13. Zhao X, Shaw AC, Wang J, Chang CC, Deng J, Su J. A novel high-throughput screening method for microbial transglutaminases with high specificity toward Gln141 of human growth hormone. J Biomol Screen. 2010 Feb; 15(2):206-12. PMID: 20086216.
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    14. Birkelund S, Morgan-Fisher M, Timmerman E, Gevaert K, Shaw AC, Christiansen G. Analysis of proteins in Chlamydia trachomatis L2 outer membrane complex, COMC. FEMS Immunol Med Microbiol. 2009 Mar; 55(2):187-95. PMID: 19187221.
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    15. Sch?ffer L, Brand CL, Hansen BF, Ribel U, Shaw AC, Slaaby R, Sturis J. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14; 376(2):380-3. PMID: 18782558.
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    16. Slaaby R, Sch?ffer L, Lautrup-Larsen I, Andersen AS, Shaw AC, Mathiasen IS, Brandt J. Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant. J Biol Chem. 2006 Sep 08; 281(36):25869-74. PMID: 16831875.
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    17. Luo Y, Zhang J, Liu Y, Shaw AC, Wang X, Wu S, Zeng X, Chen J, Gao Y, Zheng D. Comparative proteome analysis of breast cancer and normal breast. Mol Biotechnol. 2005 Mar; 29(3):233-44. PMID: 15767701.
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    18. Shaw AC, Larsen MR, Roepstorff P, Christiansen G, Birkelund S. Identification and characterization of a novel Chlamydia trachomatis reticulate body protein. FEMS Microbiol Lett. 2002 Jul 02; 212(2):193-202. PMID: 12113934.
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    19. Shaw AC, Vandahl BB, Larsen MR, Roepstorff P, Gevaert K, Vandekerckhove J, Christiansen G, Birkelund S. Characterization of a secreted Chlamydia protease. Cell Microbiol. 2002 Jul; 4(7):411-24. PMID: 12102687.
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    20. Shaw AC, Gevaert K, Demol H, Hoorelbeke B, Vandekerckhove J, Larsen MR, Roepstorff P, Holm A, Christiansen G, Birkelund S. Comparative proteome analysis of Chlamydia trachomatis serovar A, D and L2. Proteomics. 2002 Feb; 2(2):164-86. PMID: 11840563.
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