"Receptor, EphB4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eph family receptor found in a variety of adult and embryonic tissues. Unlike the majority of proteins in this class there is little or no expression of EphB4 receptor in the BRAIN. It has been found at high levels in developing mammary glands and in invasive mammary tumors.
| Descriptor ID |
D036224
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.850.750 D12.776.543.750.630.500.781
|
| Concept/Terms |
Receptor, EphB4- Receptor, EphB4
- EPHB4 Protein
- Hepatoma Transmembrane Kinase
- Kinase, Hepatoma Transmembrane
- Transmembrane Kinase, Hepatoma
- EphB4 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, EphB4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, EphB4".
This graph shows the total number of publications written about "Receptor, EphB4" by people in this website by year, and whether "Receptor, EphB4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 4 | 0 | 4 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, EphB4" by people in Profiles.
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Scalia P, Maurancy J, Giordano A, Williams SJ. Transcriptional and Post-Translational Control Mechanisms for EphB4 Expression in Physiology and Cancer Disease. Crit Rev Eukaryot Gene Expr. 2021; 31(2):83-88.
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Scalia P, Williams SJ, Giordano A. Core Element Cloning, Cis-Element Mapping and Serum Regulation of the Human EphB4 Promoter: A Novel TATA-Less Inr/MTE/DPE-Like Regulated Gene. Genes (Basel). 2019 12 02; 10(12).
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Scalia P, Pandini G, Carnevale V, Giordano A, Williams SJ. Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IRA axis in malignant mesothelioma. Oncogene. 2019 08; 38(31):5987-6001.
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Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD. Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination. Clin Cancer Res. 2019 06 01; 25(11):3352-3365.
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Bhatia S, Oweida A, Lennon S, Darragh LB, Milner D, Phan AV, Mueller AC, Van Court B, Raben D, Serkova NJ, Wang XJ, Jimeno A, Clambey ET, Pasquale EB, Karam SD. Inhibition of EphB4-Ephrin-B2 Signaling Reprograms the Tumor Immune Microenvironment in Head and Neck Cancers. Cancer Res. 2019 05 15; 79(10):2722-2735.
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Meijome TE, Ekwealor JTB, Hooker RA, Cheng YH, Ciovacco WA, Balamohan SM, Srinivasan TL, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA. C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis. J Cell Biochem. 2016 04; 117(4):959-69.
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Takasu MA, Dalva MB, Zigmond RE, Greenberg ME. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science. 2002 Jan 18; 295(5554):491-5.