"Insulator Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleic acid regulatory sequences that limit or oppose the action of ENHANCER ELEMENTS and define the boundary between differentially regulated gene loci.
| Descriptor ID |
D038101
|
| MeSH Number(s) |
G02.111.570.080.689.390 G05.360.080.689.390 G05.360.340.024.420
|
| Concept/Terms |
Insulator Elements- Insulator Elements
- Element, Insulator
- Elements, Insulator
- Insulator Element
Boundary Elements- Boundary Elements
- Boundary Element
- Element, Boundary
- Elements, Boundary
|
Below are MeSH descriptors whose meaning is more general than "Insulator Elements".
Below are MeSH descriptors whose meaning is more specific than "Insulator Elements".
This graph shows the total number of publications written about "Insulator Elements" by people in this website by year, and whether "Insulator Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Insulator Elements" by people in Profiles.
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Fujioka M, Ke W, Schedl P, Jaynes JB. The homie insulator has sub-elements with different insulating and long-range pairing properties. Genetics. 2025 04 17; 229(4).
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Fujioka M, Nezdyur A, Jaynes JB. An insulator blocks access to enhancers by an illegitimate promoter, preventing repression by transcriptional interference. PLoS Genet. 2021 04; 17(4):e1009536.
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De S, Gehred ND, Fujioka M, Chan FW, Jaynes JB, Kassis JA. Defining the Boundaries of Polycomb Domains in Drosophila. Genetics. 2020 11; 216(3):689-700.
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Chetverina D, Fujioka M, Erokhin M, Georgiev P, Jaynes JB, Schedl P. Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes. Bioessays. 2017 03; 39(3).
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Fujioka M, Mistry H, Schedl P, Jaynes JB. Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans. PLoS Genet. 2016 Feb; 12(2):e1005889.
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Ideraabdullah FY, Thorvaldsen JL, Myers JA, Bartolomei MS. Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region. Hum Mol Genet. 2014 Dec 01; 23(23):6246-59.
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Fujioka M, Sun G, Jaynes JB. The Drosophila eve insulator Homie promotes eve expression and protects the adjacent gene from repression by polycomb spreading. PLoS Genet. 2013 Oct; 9(10):e1003883.