"Receptor, Muscarinic M2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor found in the lower BRAIN, the HEART and in SMOOTH MUSCLE-containing organs. Although present in smooth muscle the M2 muscarinic receptor appears not to be involved in contractile responses.
| Descriptor ID |
D043585
|
| MeSH Number(s) |
D12.776.543.750.695.475.200 D12.776.543.750.720.360.500.200
|
| Concept/Terms |
Receptor, Muscarinic M2- Receptor, Muscarinic M2
- M2 Receptor, Muscarinic
- Muscarinic M2 Receptor
- Receptors, Muscarinic M2
- M2 Receptors, Muscarinic
- Muscarinic M2 Receptors
- Muscarinic Receptor M2
- M2, Muscarinic Receptor
- Receptor M2, Muscarinic
- Muscarinic Receptors M2
- M2, Muscarinic Receptors
- Receptors M2, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M2 [D12.776.543.750.695.475.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M2 [D12.776.543.750.720.360.500.200]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M2".
This graph shows the total number of publications written about "Receptor, Muscarinic M2" by people in this website by year, and whether "Receptor, Muscarinic M2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptor, Muscarinic M2" by people in Profiles.
-
Pera T, Penn RB. Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airway. Curr Opin Pharmacol. 2014 Jun; 16:72-81.
-
Eisenman LM. Ethanol and vestibular stimulation reveal simple and complex aspects of cerebellar heterogeneity. Cerebellum. 2011 Sep; 10(3):475-83.
-
Vishnivetskiy SA, Hosey MM, Benovic JL, Gurevich VV. Mapping the arrestin-receptor interface. Structural elements responsible for receptor specificity of arrestin proteins. J Biol Chem. 2004 Jan 09; 279(2):1262-8.
-
Murthy KS, Zhou H, Grider JR, Brautigan DL, Eto M, Makhlouf GM. Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. Biochem J. 2003 Aug 15; 374(Pt 1):145-55.
-
Shui Z, Khan IA, Haga T, Benovic JL, Boyett MR. Control of the cardiac muscarinic K+ channel by beta-arrestin 2. J Biol Chem. 2001 Apr 13; 276(15):11691-7.
-
Mundell SJ, Loudon RP, Benovic JL. Characterization of G protein-coupled receptor regulation in antisense mRNA-expressing cells with reduced arrestin levels. Biochemistry. 1999 Jul 06; 38(27):8723-32.
-
Wang YX, Dhulipala PD, Li L, Benovic JL, Kotlikoff MI. Coupling of M2 muscarinic receptors to membrane ion channels via phosphoinositide 3-kinase gamma and atypical protein kinase C. J Biol Chem. 1999 May 14; 274(20):13859-64.
-
Hosey MM, Pals-Rylaarsdam R, Lee KB, Roseberry AG, Benovic JL, Gurevich VV, B?nemann M. Molecular events associated with the regulation of signaling by M2 muscarinic receptors. Life Sci. 1999; 64(6-7):363-8.
-
Wu G, Benovic JL, Hildebrandt JD, Lanier SM. Receptor docking sites for G-protein betagamma subunits. Implications for signal regulation. J Biol Chem. 1998 Mar 27; 273(13):7197-200.
-
Sharma VK, Colecraft HM, Rubin LE, Sheu SS. Does mammalian heart contain only the M2 muscarinic receptor subtype? Life Sci. 1997; 60(13-14):1023-9.