Mary Hunt

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records
Address1025 Walnut St.
Philadelphia PA 19107
Phone215-955-7562
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Galdino ACM, Viganor L, de Castro AA, da Cunha EFF, Mello TP, Mattos LM, Pereira MD, Hunt MC, O'Shaughnessy M, Howe O, Devereux M, McCann M, Ramalho TC, Branquinha MH, Santos ALS. Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione-Based Compounds: Elastase B (LasB) as a Chemotherapeutic Target. Front Microbiol. 2019; 10:1701. PMID: 31428062.
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    2. Hunt MC, Tillander V, Alexson SE. Regulation of peroxisomal lipid metabolism: the role of acyl-CoA and coenzyme A metabolizing enzymes. Biochimie. 2014 Mar; 98:45-55. PMID: 24389458.
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    3. Tillander V, Arvidsson Nordstr?m E, Reilly J, Strozyk M, Van Veldhoven PP, Hunt MC, Alexson SE. Acyl-CoA thioesterase 9 (ACOT9) in mouse may provide a novel link between fatty acid and amino acid metabolism in mitochondria. Cell Mol Life Sci. 2014 Mar; 71(5):933-48. PMID: 23864032.
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    4. Waluk DP, Vielfort K, Derakhshan S, Aro H, Hunt MC. N-Acyl taurines trigger insulin secretion by increasing calcium flux in pancreatic ?-cells. Biochem Biophys Res Commun. 2013 Jan 04; 430(1):54-9. PMID: 23159632.
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    5. Hunt MC, Siponen MI, Alexson SE. The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism. Biochim Biophys Acta. 2012 Sep; 1822(9):1397-410. PMID: 22465940.
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    6. Waluk DP, Sucharski F, Sipos L, Silberring J, Hunt MC. Reversible lysine acetylation regulates activity of human glycine N-acyltransferase-like 2 (hGLYATL2): implications for production of glycine-conjugated signaling molecules. J Biol Chem. 2012 May 11; 287(20):16158-67. PMID: 22408254.
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    7. Chatzakos V, Sl?tis K, Djureinovic T, Helleday T, Hunt MC. N-acyl taurines are anti-proliferative in prostate cancer cells. Lipids. 2012 Apr; 47(4):355-61. PMID: 22160494.
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    8. Waluk DP, Schultz N, Hunt MC. Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans. FASEB J. 2010 Aug; 24(8):2795-803. PMID: 20305126.
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    9. Buch C, Hunt MC, Alexson SE, Hallberg E. Localization of peroxisomal matrix proteins by photobleaching. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):355-9. PMID: 19666004.
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    10. Reilly SJ, Tillander V, Ofman R, Alexson SE, Hunt MC. The nudix hydrolase 7 is an Acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis. J Biochem. 2008 Nov; 144(5):655-63. PMID: 18799520.
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    11. Hunt MC, Alexson SE. Novel functions of acyl-CoA thioesterases and acyltransferases as auxiliary enzymes in peroxisomal lipid metabolism. Prog Lipid Res. 2008 Nov; 47(6):405-21. PMID: 18538142.
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    12. Westin MAK, Hunt MC, Alexson SEH. Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse. J Biol Chem. 2007 Sep 14; 282(37):26707-26716. PMID: 17613526.
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    13. Lund?sen T, Hunt MC, Nilsson LM, Sanyal S, Angelin B, Alexson SE, Rudling M. PPARalpha is a key regulator of hepatic FGF21. Biochem Biophys Res Commun. 2007 Aug 24; 360(2):437-40. PMID: 17601491.
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    14. Dongol B, Shah Y, Kim I, Gonzalez FJ, Hunt MC. The acyl-CoA thioesterase I is regulated by PPARalpha and HNF4alpha via a distal response element in the promoter. J Lipid Res. 2007 Aug; 48(8):1781-91. PMID: 17485727.
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    15. Reilly SJ, O'Shea EM, Andersson U, O'Byrne J, Alexson SE, Hunt MC. A peroxisomal acyltransferase in mouse identifies a novel pathway for taurine conjugation of fatty acids. FASEB J. 2007 Jan; 21(1):99-107. PMID: 17116739.
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    16. Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE. Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs. FASEB J. 2006 Sep; 20(11):1855-64. PMID: 16940157.
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    17. Westin MA, Hunt MC, Alexson SE. The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes. J Biol Chem. 2005 Nov 18; 280(46):38125-32. PMID: 16141203.
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    18. Hunt MC, Yamada J, Maltais LJ, Wright MW, Podesta EJ, Alexson SE. A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases. J Lipid Res. 2005 Sep; 46(9):2029-32. PMID: 16103133.
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    19. Solaas K, Kase BF, Pham V, Bamberg K, Hunt MC, Alexson SE. Differential regulation of cytosolic and peroxisomal bile acid amidation by PPAR alpha activation favors the formation of unconjugated bile acids. J Lipid Res. 2004 Jun; 45(6):1051-60. PMID: 15026425.
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    20. Westin MA, Alexson SE, Hunt MC. Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases. J Biol Chem. 2004 May 21; 279(21):21841-8. PMID: 15007068.
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    21. O'Byrne J, Hunt MC, Rai DK, Saeki M, Alexson SE. The human bile acid-CoA:amino acid N-acyltransferase functions in the conjugation of fatty acids to glycine. J Biol Chem. 2003 Sep 05; 278(36):34237-44. PMID: 12810727.
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    22. Hansson M, Ellis E, Hunt MC, Schmitz G, Babiker A. Marked induction of sterol 27-hydroxylase activity and mRNA levels during differentiation of human cultured monocytes into macrophages. Biochim Biophys Acta. 2003 Feb 17; 1593(2-3):283-9. PMID: 12581873.
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    23. Hunt MC, Alexson SE. The role Acyl-CoA thioesterases play in mediating intracellular lipid metabolism. Prog Lipid Res. 2002 Mar; 41(2):99-130. PMID: 11755680.
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    24. Hunt MC, Solaas K, Kase BF, Alexson SE. Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism. J Biol Chem. 2002 Jan 11; 277(2):1128-38. PMID: 11673457.
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