GTP-Binding Protein gamma Subunits
"GTP-Binding Protein gamma Subunits" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterotrimeric GTP-binding protein subunits that tightly associate with GTP-BINDING PROTEIN BETA SUBUNITS. A dimer of beta and gamma subunits is formed when the GTP-BINDING PROTEIN ALPHA SUBUNIT dissociates from the GTP-binding protein heterotrimeric complex. The beta-gamma dimer can play an important role in signal transduction by interacting with a variety of second messengers.
| Descriptor ID |
D044388
|
| MeSH Number(s) |
D12.644.360.360.730 D12.776.157.325.332.730 D12.776.476.375.730 D12.776.543.325.625
|
| Concept/Terms |
GTP-Binding Protein gamma Subunits- GTP-Binding Protein gamma Subunits
- GTP Binding Protein gamma Subunits
- G-Protein gamma Subunit
- G Protein gamma Subunit
- Subunit, G-Protein gamma
- gamma Subunit, G-Protein
- GTP-Binding Protein gamma Subunit
- GTP Binding Protein gamma Subunit
|
Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein gamma Subunits".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein gamma Subunits".
This graph shows the total number of publications written about "GTP-Binding Protein gamma Subunits" by people in this website by year, and whether "GTP-Binding Protein gamma Subunits" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein gamma Subunits" by people in Profiles.
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Klayman LM, Wedegaertner PB. Inducible Inhibition of Gß? Reveals Localization-dependent Functions at the Plasma Membrane and Golgi. J Biol Chem. 2017 Feb 03; 292(5):1773-1784.
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Völkers M, Weidenhammer C, Herzog N, Qiu G, Spaich K, von Wegner F, Peppel K, Müller OJ, Schinkel S, Rabinowitz JE, Hippe HJ, Brinks H, Katus HA, Koch WJ, Eckhart AD, Friedrich O, Most P. The inotropic peptide ßARKct improves ßAR responsiveness in normal and failing cardiomyocytes through G(ß?)-mediated L-type calcium current disinhibition. Circ Res. 2011 Jan 7; 108(1):27-39.
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Irannejad R, Wedegaertner PB. Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits. J Biol Chem. 2010 Oct 15; 285(42):32393-404.
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Li G, Shi Y, Huang H, Zhang Y, Wu K, Luo J, Sun Y, Lu J, Benovic JL, Zhou N. Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3. J Biol Chem. 2010 Jul 16; 285(29):22605-18.
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Crouthamel M, Thiyagarajan MM, Evanko DS, Wedegaertner PB. N-terminal polybasic motifs are required for plasma membrane localization of Galpha(s) and Galpha(q). Cell Signal. 2008 Oct; 20(10):1900-10.
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Marrari Y, Crouthamel M, Irannejad R, Wedegaertner PB. Assembly and trafficking of heterotrimeric G proteins. Biochemistry. 2007 Jul 3; 46(26):7665-77.
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Evanko DS, Thiyagarajan MM, Takida S, Wedegaertner PB. Loss of association between activated Galpha q and Gbetagamma disrupts receptor-dependent and receptor-independent signaling. Cell Signal. 2005 Oct; 17(10):1218-28.
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Evanko DS, Thiyagarajan MM, Siderovski DP, Wedegaertner PB. Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq. J Biol Chem. 2001 Jun 29; 276(26):23945-53.