Jianping Li

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
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    Collapse Biography 
    Collapse education and training
    Peking Union Medical College and Tsinghua University, BeijingMD07/2010Hematology/Oncology
    Collapse awards and honors
    2024Charles W. Hevner Memorial Fund Research Award, Thomas Jefferson University
    2020 - 2021Young Investigator Grant, Rally Foundation for Childhood Cancer Research
    2019 - 2021Special Fellow, Leukemic & Lymphoma Society
    2019 - 2020Joint Grant Award of Rally and Bear Foundation, Rally Foundation for Childhood Cancer Research and Bear Necessities Pediatric Cancer Foundation
    201961st ASH Abstract Achievement Award, American Society of Hematology
    2018 60th ASH Abstract Achievement Award, American Society of Hematology
    2018UFHCC Poster Presentation Winner, University of Florida
    2017Outstanding Poster for Basic Research , University of Miami
    2017Award of the 8th Annual Postdoc Research Day poster presentation, University of Miami
    201660th ASH Abstract Achievement Award, American Society of Hematology

    Collapse Overview 
    Collapse webpage

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dupere-Richer D, Riva A, Barwick BG, Maji S, Casellas Roman H, Li J, De U, Sobh A, Quickstad G, Piper C, Kulis M, Ezponda T, Martín-Subero JI, Tonon G, Zhang W, Mitsiades CS, Boise LH, Bennett RL, Licht JD. KDM6A Regulates Immune Response Genes in Multiple Myeloma. Blood. 2024 Jul 24. PMID: 39046770.
      Citations:    
    2. Nie DY, Tabor JR, Li J, Kutera M, St-Germain J, Hanley RP, Wolf E, Paulakonis E, Kenney TMG, Duan S, Shrestha S, Owens DDG, Maitland MER, Pon A, Szewczyk M, Lamberto AJ, Menes M, Li F, Penn LZ, Barsyte-Lovejoy D, Brown NG, Barsotti AM, Stamford AW, Collins JL, Wilson DJ, Raught B, Licht JD, James LI, Arrowsmith CH. Recruitment of FBXO22 for targeted degradation of NSD2. Nat Chem Biol. 2024 Jul 04. PMID: 38965384.
      Citations:    
    3. Morozov VM, Riva A, Sarwar S, Kim WJ, Li J, Zhou L, Licht JD, Daaka Y, Ishov AM. HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers. Nucleic Acids Res. 2023 Oct 27; 51(19):10194-10217. PMID: 37638746.
      Citations:    
    4. Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Román HL, Posada LM, Gunaratne C, Li J, Dupéré-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks. Clin Cancer Res. 2022 Feb 15; 28(4):756-769. PMID: 34716195.
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    5. Li L, Sheng P, Li T, Fields CJ, Hiers NM, Wang Y, Li J, Guardia CM, Licht JD, Xie M. Widespread microRNA degradation elements in target mRNAs can assist the encoded proteins. Genes Dev. 2021 Dec 01; 35(23-24):1595-1609. PMID: 34819352.
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    6. Li J, Hlavka-Zhang J, Shrimp JH, Piper C, Dupéré-Richér D, Roth JS, Jing D, Casellas Román HL, Troche C, Swaroop A, Kulis M, Oyer JA, Will CM, Shen M, Riva A, Bennett RL, Ferrando AA, Hall MD, Lock RB, Licht JD. PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia. Cancer Discov. 2022 Jan; 12(1):186-203. PMID: 34417224.
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    7. Casellas Román HL, Venugopal K, Feng Y, Shabashvili DE, Posada LM, Li J, Guryanova OA. DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents. Leuk Res. 2020 Jul; 94:106372. PMID: 32445940.
      Citations:    
    8. Jiang Y, Gao R, Cao C, Forbes L, Li J, Freeberg S, Fredenburg KM, Justice JM, Silver NL, Wu L, Varma S, West R, Licht JD, Zajac-Kaye M, Kentsis A, Kaye FJ. MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma. Oral Oncol. 2019 Nov; 98:147-155. PMID: 31606723.
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    9. Xie Y, Shi X, Sheng K, Han G, Li W, Zhao Q, Jiang B, Feng J, Li J, Gu Y. PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review). Mol Med Rep. 2019 Feb; 19(2):783-791. PMID: 30535469.
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    10. Zhang P, Chen Z, Li R, Guo Y, Shi H, Bai J, Yang H, Sheng M, Li Z, Li Z, Li J, Chen S, Yuan W, Cheng T, Xu M, Zhou Y, Yang FC. Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates. Cell Discov. 2018; 4:4. PMID: 29423272.
      Citations:    
    11. Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, Zhou Y, Nimer SD, Harbour JW, Wahlestedt C, Xu M, Yang FC. Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. 2018 Jan 18; 131(3):328-341. PMID: 29113963.
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    12. Lu S, Ge M, Zheng Y, Li J, Feng X, Feng S, Huang J, Feng Y, Yang D, Shi J, Chen F, Han Z. CD106 is a novel mediator of bone marrow mesenchymal stem cells via NF-?B in the bone marrow failure of acquired aplastic anemia. Stem Cell Res Ther. 2017 Aug 01; 8(1):178. PMID: 28764810.
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    13. Li J, He F, Zhang P, Chen S, Shi H, Sun Y, Guo Y, Yang H, Man N, Greenblatt S, Li Z, Guo Z, Zhou Y, Wang L, Morey L, Williams S, Chen X, Wang QT, Nimer SD, Yu P, Wang QF, Xu M, Yang FC. Loss of Asxl2 leads to myeloid malignancies in mice. Nat Commun. 2017 Jun 08; 8:15456. PMID: 28593990.
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    14. Li Z, Zhang P, Yan A, Guo Z, Ban Y, Li J, Chen S, Yang H, He Y, Li J, Guo Y, Zhang W, Hajiramezanali E, An H, Fajardo D, Harbour JW, Ruan Y, Nimer SD, Yu P, Chen X, Xu M, Yang FC. ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis. Sci Adv. 2017 Jan; 3(1):e1601602. PMID: 28116354.
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    15. Li J, Yang S, Lu S, Zhao H, Feng J, Li W, Ma F, Ren Q, Liu B, Zhang L, Zheng Y, Han ZC. Differential gene expression profile associated with the abnormality of bone marrow mesenchymal stem cells in aplastic anemia. PLoS One. 2012; 7(11):e47764. PMID: 23144828.
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    16. Li J, Lu S, Yang S, Xing W, Feng J, Li W, Zhao Q, Wu H, Ge M, Ma F, Zhao H, Liu B, Zhang L, Zheng Y, Han ZC. Impaired immunomodulatory ability of bone marrow mesenchymal stem cells on CD4(+) T cells in aplastic anemia. Results Immunol. 2012; 2:142-7. PMID: 24371578.
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    17. Li J, Zhao Q, Xing W, Feng J, Wu H, Li H, Ge M, Tian K, Li X, Zhou J, Liu B, Zhang L, Zheng Y, Han ZC. Interleukin-27 enhances the production of tumour necrosis factor-a and interferon-? by bone marrow T lymphocytes in aplastic anaemia. Br J Haematol. 2011 Jun; 153(6):764-72. PMID: 21506940.
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    18. Li JP, Wu H, Xing W, Yang SG, Lu SH, Du WT, Yu JX, Chen F, Zhang L, Han ZC. Interleukin-27 as a negative regulator of human neutrophil function. Scand J Immunol. 2010 Oct; 72(4):284-92. PMID: 20883313.
      Citations:    
    19. Yu J, Zheng C, Ren X, Li J, Liu M, Zhang L, Liang L, Du W, Han ZC. Intravenous administration of bone marrow mesenchymal stem cells benefits experimental autoimmune myasthenia gravis mice through an immunomodulatory action. Scand J Immunol. 2010 Sep; 72(3):242-9. PMID: 20696022.
      Citations:    
    20. Li JP, Zheng CL, Han ZC. Abnormal immunity and stem/progenitor cells in acquired aplastic anemia. Crit Rev Oncol Hematol. 2010 Aug; 75(2):79-93. PMID: 20045349.
      Citations:    
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