Daniel Erkes

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-7592
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hines PJ, Hurtley SM, Jiang D, Uzogara E, Erkes DA, Grocholski B, Malo CS, Alderton G, Osborne IS, Ferrarelli LK, Smith HJ, Ray LB. In Science Journals. Science. 2023 Jan 06; 379(6627):37-39. PMID: 36603084.
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    2. Grocholski B, Lavine MS, Erkes DA, Dennis J, Stern P, Osborne IS, Vignieri S, Jiang D, Ash C, Maroso M, Ferrarelli LK. In Science Journals. Science. 2022 08 26; 377(6609):936-937. PMID: 36007023.
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    3. Hines PJ, Lopez B, Ash C, Yeston J, Ray LB, Smith OM, Suleymanov Y, Osborne IS, Foley JF, Erkes DA. In Science Journals. Science. 2022 06 10; 376(6598):1179-1181. PMID: 35679402.
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    4. Vignieri S, Stern P, Szuromi P, Grocholski B, Yeston J, Hodges K, Lopez B, Maroso M, Zahn LM, Jiang D, Scanlon ST, Lavine MS, Erkes DA, Ferrarelli LK, Lou XWD, Stajic J. In Science Journals. Science. 2022 05 13; 376(6594):708-710. PMID: 35549412.
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    5. Medina M, Stern P, Erkes DA, Lavine MS, Nusinovich Y, Jiang D, Smith KT, Yeston J, Ferrarelli LK, Zahn LM, Alderton G, Charneski CA, Szuromi P, Vignieri S, Ash C. In Science Journals. Science. 2022 04 29; 376(6592):471-473. PMID: 35482851.
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    6. Purnell BA, Grocholski B, Vinson V, Yeston J, Szuromi P, Czajka C, Osborne IS, Bouchard LS, Alderton G, Sugden AM, Hurtley SM, Stajic J, Nusinovich Y, Ferrarelli LK, Vignieri S, Erkes DA, McDowell J. In Science Journals. Science. 2022 04 22; 376(6591):364-366. PMID: 35446651.
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    7. Hodges K, Hines PJ, Suleymanov Y, Lavine MS, Osborne IS, Stajic J, Purnell BA, Erkes DA, Zahn LM, Vinson V, Grocholski B, Nusinovich Y, Malo CS, Ferrarelli LK, Ash C. In Science Journals. Science. 2022 04 08; 376(6589):148-150. PMID: 35389797.
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    8. Vinson V, Szuromi P, Lavine MS, Erkes DA, Osborne IS, Chemler S, Stern P, Yeston J, Zahn LM, Grocholski B, Alderton G, Ash C, Charneski CA, VanHook AM. In Science Journals. Science. 2022 03 25; 375(6587):1368-1370. PMID: 35324289.
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    9. Smith HJ, Zahn LM, Suleymanov Y, Lopez B, Grocholski B, Stajic J, Erkes DA, Maroso M, Alderton G, Stern P, Kelly PN, Smith KT, Yeston J, Jiang D, Funk MA, Wong W. In Science Journals. Science. 2022 Mar 18; 375(6586):1241-1243. PMID: 35298252.
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    10. Vignieri S, Yeston J, Lavine MS, Vinson V, Stajic J, Malo CS, Sugden AM, Nusinovich Y, Purnell BA, Ray LB, VanHook AM, Erkes DA, Hurtley SM. In Science Journals. Science. 2022 Feb 18; 375(6582):731-733. PMID: 35175815.
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    11. Vignieri S, Vinson V, Ferrarelli LK, Stajic J, Jiang D, Clauset A, Purnell BA, Hines PJ, Sugden AM, Erkes DA, Malo CS, Szuromi P. In Science Journals. Science. 2022 Jan 28; 375(6579):398-400. PMID: 35084983.
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    12. Maroso M, Stajic J, Yeston J, Smith KT, Erkes DA, Hurtley SM, Hines PJ, Alderton G, Ash C, Vinson V, Grocholski B, Osborne IS, Sugden AM, Nusinovich Y, Norton M, VanHook AM. In Science Journals. Science. 2022 Jan 14; 375(6577):155-157. PMID: 35025653.
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    13. Purnell BA, Stern P, Funk MA, Yeston J, Hodges K, Maroso M, Alderton G, Smith HJ, Lavine MS, Hines PJ, Scanlon ST, Suleymanov Y, Erkes DA, Wong W, Smith KT. In Science Journals. Science. 2021 Nov 05; 374(6568):704-706. PMID: 34735247.
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    14. Funk MA, Diesner J, Jiang D, Stajic J, Vinson V, Foley JF, Smith HJ, Osborne IS, Hurtley SM, Suleymanov Y, Smith KT, Purnell BA, Hines PJ, Erkes DA, Stern P, Maroso M. In Science Journals. Science. 2021 Sep 03; 373(6559):1100-1102. PMID: 34516869.
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    15. Knudson CJ, FĂ©rez M, Alves-Peixoto P, Erkes DA, Melo-Silva CR, Tang L, Snyder CM, Sigal LJ. Mechanisms of Antiviral Cytotoxic CD4 T Cell Differentiation. J Virol. 2021 09 09; 95(19):e0056621. PMID: 34260270.
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    16. Teh JLF, Erkes DA, Cheng PF, Tiago M, Wilski NA, Field CO, Chervoneva I, Levesque MP, Xu X, Dummer R, Aplin AE. Activation of CD8+ T Cells Contributes to Antitumor Effects of CDK4/6 Inhibitors plus MEK Inhibitors. Cancer Immunol Res. 2020 Sep; 8(9):1114-1121. PMID: 32661093.
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    17. Tiago M, Capparelli C, Erkes DA, Purwin TJ, Heilman SA, Berger AC, Davies MA, Aplin AE. Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma. Br J Cancer. 2020 Jan 14. PMID: 31932756.
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    18. Rosenbaum SR, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue PA, Chervoneva I, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin AE. FOXD3 Regulates VISTA Expression in Melanoma. Cell Rep. 2020 Jan 14; 30(2):510-524.e6. PMID: 31940493.
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    19. Erkes DA, Cai W, Sanchez IM, Purwin TJ, Rogers C, Field CO, Berger AC, Hartsough EJ, Rodeck U, Alnemri ES, Aplin AE. Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis. Cancer Discov. 2019 Dec 03. PMID: 31796433.
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    20. Erkes DA, Rosenbaum SR, Field CO, Chervoneva I, Villanueva J, Aplin AE. PLX3397 inhibits the accumulation of intra-tumoral macrophages and improves BET inhibitor efficacy in melanoma. Pigment Cell Melanoma Res. 2019 Nov 06. PMID: 31696640.
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    21. Sanchez IM, Purwin TJ, Chervoneva I, Erkes DA, Nguyen MQ, Davies MA, Nathanson KL, Kemper K, Peeper DS, Aplin AE. In vivo ERK1/2 reporter predictively models response and resistance to combined BRAF and MEK inhibitors in melanoma. Mol Cancer Ther. 2019 Jul 03. PMID: 31270153.
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    22. Erkes DA, Field CO, Capparelli C, Tiago M, Purwin TJ, Chervoneva I, Berger AC, Hartsough EJ, Villanueva J, Aplin AE. The next generation BET inhibitor, PLX51107, delays melanoma growth in a CD8-mediated manner. Pigment Cell Melanoma Res. 2019 May 07. PMID: 31063649.
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    23. Rogers C, Erkes DA, Nardone A, Aplin AE, Fernandes-Alnemri T, Alnemri ES. Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation. Nat Commun. 2019 04 11; 10(1):1689. PMID: 30976076.
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    24. Hartsough EJ, Weiss MB, Heilman SA, Purwin TJ, Kugel CH, Rosenbaum SR, Erkes DA, Tiago M, HooKim K, Chervoneva I, Aplin AE. CADM1 is a TWIST1-regulated suppressor of invasion and survival. Cell Death Dis. 2019 Mar 25; 10(4):281. PMID: 30911007.
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    25. Nikbakht N, Tiago M, Erkes DA, Chervoneva I, Aplin AE. BET inhibition modifies melanoma infiltrating T cells and enhances response to PD-L1 blockade. J Invest Dermatol. 2019 Jan 28. PMID: 30703359.
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    26. Erkes DA, Wilski NA, Snyder CM. Intratumoral infection by CMV may change the tumor environment by directly interacting with tumor-associated macrophages to promote cancer immunity. Hum Vaccin Immunother. 2017 Jun 12; 1-8. PMID: 28604162.
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    27. Erkes DA, Smith CJ, Wilski NA, Caldeira-Dantas S, Mohgbeli T, Snyder CM. Virus-Specific CD8+ T Cells Infiltrate Melanoma Lesions and Retain Function Independently of PD-1 Expression. J Immunol. 2017 Apr 01; 198(7):2979-2988. PMID: 28202614.
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    28. Erkes DA, Xu G, Daskalakis C, Zurbach KA, Wilski NA, Moghbeli T, Hill AB, Snyder CM. Intratumoral Infection with Murine Cytomegalovirus Synergizes with PD-L1 Blockade to Clear Melanoma Lesions and Induce Long-term Immunity. Mol Ther. 2016 Aug; 24(8):1444-55. PMID: 27434584.
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    29. Quinn M, Erkes DA, Snyder CM. Cytomegalovirus and immunotherapy: opportunistic pathogen, novel target for cancer and a promising vaccine vector. Immunotherapy. 2016 Feb; 8(2):211-21. PMID: 26786895.
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    30. Erkes DA, Selvan SR. Hapten-induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunity. J Immunol Res. 2014; 2014:175265. PMID: 24949488.
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