Macromolecular Substances
"Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure.
| Descriptor ID |
D046911
|
| MeSH Number(s) |
D05
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Macromolecular Substances".
Below are MeSH descriptors whose meaning is more specific than "Macromolecular Substances".
This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 9 | 9 |
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 10 | 10 |
| 2004 | 0 | 7 | 7 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 4 | 4 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Macromolecular Substances" by people in Profiles.
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Shen S, Davidson GA, Yang K, Zhuang Z. Photo-activatable Ub-PCNA probes reveal new structural features of the Saccharomyces cerevisiae Pol?/PCNA complex. Nucleic Acids Res. 2021 09 20; 49(16):9374-9388.
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Quinn CM, Wang M, Polenova T. NMR of Macromolecular Assemblies and Machines at 1 GHz and Beyond: New Transformative Opportunities for Molecular Structural Biology. Methods Mol Biol. 2018; 1688:1-35.
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Sydor AM, Czymmek KJ, Puchner EM, Mennella V. Super-Resolution Microscopy: From Single Molecules to Supramolecular Assemblies. Trends Cell Biol. 2015 Dec; 25(12):730-748.
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Luo T, He L, Theato P, Kiick KL. Thermoresponsive self-assembly of nanostructures from a collagen-like peptide-containing diblock copolymer. Macromol Biosci. 2015 Jan; 15(1):111-23.
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Gu L, Nusblat LM, Tishbi N, Noble SC, Pinson CM, Mintzer E, Roth CM, Uhrich KE. Cationic amphiphilic macromolecule (CAM)-lipid complexes for efficient siRNA gene silencing. J Control Release. 2014 Jun 28; 184:28-35.
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Kelley EG, Murphy RP, Seppala JE, Smart TP, Hann SD, Sullivan MO, Epps TH. Size evolution of highly amphiphilic macromolecular solution assemblies via a distinct bimodal pathway. Nat Commun. 2014 Apr 07; 5:3599.
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Seppala JE, Lewis RL, Epps TH. Spatial and orientation control of cylindrical nanostructures in ABA triblock copolymer thin films by raster solvent vapor annealing. ACS Nano. 2012 Nov 27; 6(11):9855-62.
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Opitz AW, Czymmek KJ, Wickstrom E, Wagner NJ. Uptake, efflux, and mass transfer coefficient of fluorescent PAMAM dendrimers into pancreatic cancer cells. Biochim Biophys Acta. 2013 Feb; 1828(2):294-301.
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Grieshaber SE, Farran AJ, Bai S, Kiick KL, Jia X. Tuning the properties of elastin mimetic hybrid copolymers via a modular polymerization method. Biomacromolecules. 2012 Jun 11; 13(6):1774-86.
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Steplewski A, Kasinskas A, Fertala A. Remodeling of the dermal-epidermal junction in bilayered skin constructs after silencing the expression of the p.R2622Q and p.G2623C collagen VII mutants. Connect Tissue Res. 2012; 53(5):379-89.