Mitogen-Activated Protein Kinase 8
"Mitogen-Activated Protein Kinase 8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A c-jun amino-terminal kinase that is activated by environmental stress and pro-inflammatory cytokines. Several isoforms of the protein with molecular sizes of 43 and 48 KD exist due to multiple ALTERNATIVE SPLICING.
Descriptor ID |
D048055
|
MeSH Number(s) |
D08.811.913.696.620.682.700.567.374.500 D12.644.360.450.340.500 D12.776.476.450.340.500
|
Concept/Terms |
Mitogen-Activated Protein Kinase 8- Mitogen-Activated Protein Kinase 8
- Mitogen Activated Protein Kinase 8
- c-jun Kinase-1
- c jun Kinase 1
- SAP Kinase-1
- SAP Kinase 1
- Stress-Activated Protein Kinase gamma
- Stress Activated Protein Kinase gamma
- c-jun N-Terminal Kinase 1
- c jun N Terminal Kinase 1
- MAPK8 Mitogen-Activated Protein Kinase
- MAPK8 Mitogen Activated Protein Kinase
- JNK1 Kinase
- SAPK1 Mitogen-Activated Protein Kinase
- SAPK1 Mitogen Activated Protein Kinase
- Stress-Activated Protein Kinase 1
- Stress Activated Protein Kinase 1
- Stress-Activated Protein Kinase JNK1
- Stress Activated Protein Kinase JNK1
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 8".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 8".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 8" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 8" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2003 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2016 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Mitogen-Activated Protein Kinase 8" by people in Profiles.
-
Sen A, Hongpaisan J, Wang D, Nelson TJ, Alkon DL. Protein Kinase C? (PKC?) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95. J Biol Chem. 2016 08 05; 291(32):16462-76.
-
Vasilevskaya IA, Selvakumaran M, Roberts D, O'Dwyer PJ. JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy. Mol Cancer Res. 2016 08; 14(8):753-63.
-
Vasilevskaya IA, Selvakumaran M, Hierro LC, Goldstein SR, Winkler JD, O'Dwyer PJ. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents. Clin Cancer Res. 2015 Sep 15; 21(18):4143-52.
-
Thévenin AF, Zony CL, Bahnson BJ, Colman RF. GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Sci. 2011 May; 20(5):834-48.
-
Alexaki VI, Javelaud D, Mauviel A. JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis. Pigment Cell Melanoma Res. 2008 Aug; 21(4):429-38.
-
Zhang X, Schroeder A, Callahan EM, Coyle BM, Wang N, Erickson KA, Schuman JS, Fini ME. Constitutive signalling pathway activity in trabecular meshwork cells from glaucomatous eyes. Exp Eye Res. 2006 Jun; 82(6):968-73.
-
Wendling J, Marchand A, Mauviel A, Verrecchia F. 5-fluorouracil blocks transforming growth factor-beta-induced alpha 2 type I collagen gene (COL1A2) expression in human fibroblasts via c-Jun NH2-terminal kinase/activator protein-1 activation. Mol Pharmacol. 2003 Sep; 64(3):707-13.