"MAP Kinase Kinase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase kinase with specificity for JNK MITOGEN-ACTIVATED PROTEIN KINASES. It takes part in a SIGNAL TRANSDUCTION pathway that is activated in response to CYTOKINES.
| Descriptor ID |
D048688
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| MeSH Number(s) |
D08.811.913.696.620.682.700.565.700 D08.811.913.696.620.682.725.200.700 D12.644.360.440.700 D12.776.476.440.700
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| Concept/Terms |
MAP Kinase Kinase 7- MAP Kinase Kinase 7
- PRKMK7
- Mitogen-Activated Protein Kinase Kinase 7
- Mitogen Activated Protein Kinase Kinase 7
- MAPKK7 Protein Kinase
- Protein Kinase, MAPKK7
- MEK7 Protein Kinase
- Protein Kinase, MEK7
- SKK4 Protein Kinase
- Protein Kinase, SKK4
- JNK-Activating Kinase 2
- JNK Activating Kinase 2
- SEK2 Protein Kinase
- Protein Kinase, SEK2
|
Below are MeSH descriptors whose meaning is more general than "MAP Kinase Kinase 7".
Below are MeSH descriptors whose meaning is more specific than "MAP Kinase Kinase 7".
This graph shows the total number of publications written about "MAP Kinase Kinase 7" by people in this website by year, and whether "MAP Kinase Kinase 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "MAP Kinase Kinase 7" by people in Profiles.
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Ray D, Yun YC, Idris M, Cheng S, Boot A, Iain TBH, Rozen SG, Tan P, Epstein DM. A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation. Proc Natl Acad Sci U S A. 2020 07 14; 117(28):16391-16400.
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Thévenin AF, Zony CL, Bahnson BJ, Colman RF. Activation by phosphorylation and purification of human c-Jun N-terminal kinase (JNK) isoforms in milligram amounts. Protein Expr Purif. 2011 Feb; 75(2):138-46.
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Vasilevskaya IA, Selvakumaran M, O'Dwyer PJ. Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin. Mol Pharmacol. 2008 Jul; 74(1):246-54.