T-Lymphocytes, Regulatory

"T-Lymphocytes, Regulatory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

CD4-positive T cells that inhibit immunopathology or autoimmune disease in vivo. They inhibit the immune response by influencing the activity of other cell types. Regulatory T-cells include naturally occurring CD4+CD25+ cells, IL-10 secreting Tr1 cells, and Th3 cells.

Descriptor ID	D050378
MeSH Number(s)	A11.118.637.555.567.550.500.700 A11.118.637.555.567.569.200.700 A11.118.637.555.567.569.500.700 A15.145.229.637.555.567.550.500.700 A15.145.229.637.555.567.569.200.700 A15.145.229.637.555.567.569.500.700 A15.382.490.555.567.550.500.700 A15.382.490.555.567.569.200.700 A15.382.490.555.567.569.500.700
Concept/Terms	T-Lymphocytes, Regulatory T-Lymphocytes, Regulatory T Lymphocytes, Regulatory Regulatory T-Lymphocytes Regulatory T Lymphocytes Regulatory T-Lymphocyte T-Lymphocyte, Regulatory Regulatory T-Cells Regulatory T Cells T-Cells, Regulatory T Cells, Regulatory Treg Cells Cell, Treg Cells, Treg Treg Cell Th3 Cells Th3 Cells Cell, Th3 Cells, Th3 Th3 Cell Suppressor T-Lymphocytes, Naturally-Occurring Suppressor T-Lymphocytes, Naturally-Occurring Naturally-Occurring Suppressor T-Lymphocyte Naturally-Occurring Suppressor T-Lymphocytes Suppressor T Lymphocytes, Naturally Occurring Suppressor T-Lymphocyte, Naturally-Occurring Suppressor T-Cells, Naturally-Occurring Naturally-Occurring Suppressor T-Cell Naturally-Occurring Suppressor T-Cells Suppressor T Cells, Naturally Occurring Suppressor T-Cell, Naturally-Occurring T-Cell, Naturally-Occurring Suppressor T-Cells, Naturally-Occurring Suppressor Tr1 Cells Tr1 Cells Cell, Tr1 Cells, Tr1 Tr1 Cell

Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes, Regulatory".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
Lymphocyte Subsets [A11.118.637.555.567.550]
T-Lymphocyte Subsets [A11.118.637.555.567.550.500]
T-Lymphocytes, Regulatory [A11.118.637.555.567.550.500.700]
T-Lymphocytes [A11.118.637.555.567.569]
CD4-Positive T-Lymphocytes [A11.118.637.555.567.569.200]
T-Lymphocytes, Regulatory [A11.118.637.555.567.569.200.700]
T-Lymphocyte Subsets [A11.118.637.555.567.569.500]
T-Lymphocytes, Regulatory [A11.118.637.555.567.569.500.700]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
Lymphocyte Subsets [A15.145.229.637.555.567.550]
T-Lymphocyte Subsets [A15.145.229.637.555.567.550.500]
T-Lymphocytes, Regulatory [A15.145.229.637.555.567.550.500.700]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD4-Positive T-Lymphocytes [A15.145.229.637.555.567.569.200]
T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.200.700]
T-Lymphocyte Subsets [A15.145.229.637.555.567.569.500]
T-Lymphocytes, Regulatory [A15.145.229.637.555.567.569.500.700]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
Lymphocyte Subsets [A15.382.490.555.567.550]
T-Lymphocyte Subsets [A15.382.490.555.567.550.500]
T-Lymphocytes, Regulatory [A15.382.490.555.567.550.500.700]
T-Lymphocytes [A15.382.490.555.567.569]
CD4-Positive T-Lymphocytes [A15.382.490.555.567.569.200]
T-Lymphocytes, Regulatory [A15.382.490.555.567.569.200.700]
T-Lymphocyte Subsets [A15.382.490.555.567.569.500]
T-Lymphocytes, Regulatory [A15.382.490.555.567.569.500.700]

Below are MeSH descriptors whose meaning is related to "T-Lymphocytes, Regulatory".

Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes, Regulatory".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "T-Lymphocytes, Regulatory" by people in this website by year, and whether "T-Lymphocytes, Regulatory" was a major or minor topic of these publications.

Bar chart showing 54 publications over 17 distinct years, with a maximum of 8 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	2	0	2
2006	2	0	2
2007	3	0	3
2008	4	3	7
2009	6	2	8
2010	3	4	7
2011	3	2	5
2012	2	0	2
2013	1	0	1
2014	3	1	4
2015	1	1	2
2016	1	0	1
2018	0	1	1
2019	1	1	2
2020	1	1	2
2021	3	0	3
2022	1	1	2

Below are the most recent publications written about "T-Lymphocytes, Regulatory" by people in Profiles.

Yan Y, Huang L, Liu Y, Yi M, Chu Q, Jiao D, Wu K. Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity. J Hematol Oncol. 2022 08 10; 15(1):104.

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Piper M, Van Court B, Mueller A, Watanabe S, Bickett T, Bhatia S, Darragh LB, Mayeda M, Nguyen D, Gadwa J, Knitz M, Corbo S, Morgan R, Lee JJ, Dent A, Goodman K, Messersmith W, Schulick R, Del Chiaro M, Zhu Y, Kedl RM, Lenz L, Karam SD. Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma. Clin Cancer Res. 2022 Mar 01; 28(5):1013-1026.

View in: PubMed
Hwang D, Boehm A, Rostami A, Zhang GX, Ciric B. Oral D-mannose treatment suppresses experimental autoimmune encephalomyelitis via induction of regulatory T cells. J Neuroimmunol. 2022 01 15; 362:577778.

View in: PubMed
Ramos-Ramírez P, Malmhäll C, Tliba O, Rådinger M, Bossios A. Adiponectin/AdipoR1 Axis Promotes IL-10 Release by Human Regulatory T Cells. Front Immunol. 2021; 12:677550.

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Ni D, Tang T, Lu Y, Xu K, Shao Y, Saaoud F, Saredy J, Liu L, Drummer C, Sun Y, Hu W, Lopez-Pastrana J, Luo JJ, Jiang X, Choi ET, Wang H, Yang X. Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways. Front Immunol. 2021; 12:678201.

View in: PubMed
Podojil JR, Glaser AP, Baker D, Courtois ET, Fantini D, Yu Y, Eaton V, Sivajothi S, Chiang M, Das A, McLaughlin KA, Robson P, Miller SD, Meeks JJ. Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma. Oncoimmunology. 2020; 9(1):1744897.

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Chan AY, Leiding JW, Liu X, Logan BR, Burroughs LM, Allenspach EJ, Skoda-Smith S, Uzel G, Notarangelo LD, Slatter M, Gennery AR, Smith AR, Pai SY, Jordan MB, Marsh RA, Cowan MJ, Dvorak CC, Craddock JA, Prockop SE, Chandrakasan S, Kapoor N, Buckley RH, Parikh S, Chellapandian D, Oshrine BR, Bednarski JJ, Cooper MA, Shenoy S, Davila Saldana BJ, Forbes LR, Martinez C, Haddad E, Shyr DC, Chen K, Sullivan KE, Heimall J, Wright N, Bhatia M, Cuvelier GDE, Goldman FD, Meyts I, Miller HK, Seidel MG, Vander Lugt MT, Bacchetta R, Weinacht KG, Andolina JR, Caywood E, Chong H, de la Morena MT, Aquino VM, Shereck E, Walter JE, Dorsey MJ, Seroogy CM, Griffith LM, Kohn DB, Puck JM, Pulsipher MA, Torgerson TR. Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. Front Immunol. 2020; 11:239.

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Oweida AJ, Darragh L, Phan A, Binder D, Bhatia S, Mueller A, Court BV, Milner D, Raben D, Woessner R, Heasley L, Nemenoff R, Clambey E, Karam SD. STAT3 Modulation of Regulatory T Cells in Response to Radiation Therapy in Head and Neck Cancer. J Natl Cancer Inst. 2019 12 01; 111(12):1339-1349.

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Lennon S, Oweida A, Milner D, Phan AV, Bhatia S, Van Court B, Darragh L, Mueller AC, Raben D, Martínez-Torrecuadrada JL, Pitts TM, Somerset H, Jordan KR, Hansen KC, Williams J, Messersmith WA, Schulick RD, Owens P, Goodman KA, Karam SD. Pancreatic Tumor Microenvironment Modulation by EphB4-ephrinB2 Inhibition and Radiation Combination. Clin Cancer Res. 2019 06 01; 25(11):3352-3365.

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Cho H, Jaime H, de Oliveira RP, Kang B, Spolski R, Vaziri T, Myers TG, Thovarai V, Shen Z, Fox JG, Leonard WJ, Kelsall BL. Defective IgA response to atypical intestinal commensals in IL-21 receptor deficiency reshapes immune cell homeostasis and mucosal immunity. Mucosal Immunol. 2019 01; 12(1):85-96.

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