Insulin-Secreting Cells

"Insulin-Secreting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.

Descriptor ID	D050417
MeSH Number(s)	A03.734.414.131 A06.390.131 A06.407.414.087 A11.382.625.092 A11.436.294.092
Concept/Terms	Insulin-Secreting Cells Insulin-Secreting Cells Cell, Insulin-Secreting Cells, Insulin-Secreting Insulin Secreting Cells Insulin-Secreting Cell beta Cells, Pancreatic Pancreatic beta Cell beta Cell, Pancreatic Pancreatic B Cells B Cell, Pancreatic B Cells, Pancreatic Pancreatic B Cell Pancreatic beta Cells

Below are MeSH descriptors whose meaning is more general than "Insulin-Secreting Cells".

Anatomy [A]
Digestive System [A03]
Pancreas [A03.734]
Islets of Langerhans [A03.734.414]
Insulin-Secreting Cells [A03.734.414.131]
Endocrine System [A06]
Enteroendocrine Cells [A06.390]
Insulin-Secreting Cells [A06.390.131]
Endocrine Glands [A06.407]
Islets of Langerhans [A06.407.414]
Insulin-Secreting Cells [A06.407.414.087]
Cells [A11]
Endocrine Cells [A11.382]
Enteroendocrine Cells [A11.382.625]
Insulin-Secreting Cells [A11.382.625.092]
Epithelial Cells [A11.436]
Enteroendocrine Cells [A11.436.294]
Insulin-Secreting Cells [A11.436.294.092]

Below are MeSH descriptors whose meaning is related to "Insulin-Secreting Cells".

Below are MeSH descriptors whose meaning is more specific than "Insulin-Secreting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin-Secreting Cells" by people in this website by year, and whether "Insulin-Secreting Cells" was a major or minor topic of these publications.

Bar chart showing 18 publications over 11 distinct years, with a maximum of 4 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2006	1	0	1
2007	2	1	3
2008	1	0	1
2009	1	1	2
2010	1	0	1
2011	1	0	1
2012	4	0	4
2013	1	1	2
2017	1	0	1
2024	1	0	1

Below are the most recent publications written about "Insulin-Secreting Cells" by people in Profiles.

Varney MJ, Benovic JL. The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic ?-Cell Function and Diabetes. Pharmacol Rev. 2024 Feb 13; 76(2):267-299.

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Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, ?berg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Gr?nborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honor? C, Ahnfelt-R?nne J, Hecksher-S?rensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. The EndoC-?H1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates. Mol Metab. 2018 02; 8:144-157.

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Baldi JC, Manning PJ, Hofman PL, Walker RJ. Comment on: TODAY Study Group. Effects of metformin, metformin plus rosiglitazone, and metformin plus lifestyle on insulin sensitivity and ?-cell function in TODAY. Diabetes Care 2013;36:1749-1757. Diabetes Care. 2013 Dec; 36(12):e223.

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Muniyappa R, Sable S, Ouwerkerk R, Mari A, Gharib AM, Walter M, Courville A, Hall G, Chen KY, Volkow ND, Kunos G, Huestis MA, Skarulis MC. Metabolic effects of chronic cannabis smoking. Diabetes Care. 2013 Aug; 36(8):2415-22.

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Gadhia MM, Maliszewski AM, O'Meara MC, Thorn SR, Lavezzi JR, Limesand SW, Hay WW, Brown LD, Rozance PJ. Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase ?-cell mass in fetal sheep. Am J Physiol Endocrinol Metab. 2013 Feb 15; 304(4):E352-62.

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Waluk DP, Vielfort K, Derakhshan S, Aro H, Hunt MC. N-Acyl taurines trigger insulin secretion by increasing calcium flux in pancreatic ?-cells. Biochem Biophys Res Commun. 2013 Jan 04; 430(1):54-9.

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Lavezzi JR, Thorn SR, O'Meara MC, LoTurco D, Brown LD, Hay WW, Rozance PJ. Increased fetal insulin concentrations for one week fail to improve insulin secretion or ?-cell mass in fetal sheep with chronically reduced glucose supply. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 01; 304(1):R50-8.

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Zhou L, Pelengaris S, Abouna S, Young J, Epstein D, Herold J, Nattkemper TW, Nakhai H, Khan M. Re-expression of IGF-II is important for beta cell regeneration in adult mice. PLoS One. 2012; 7(9):e43623.

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Encina G, Ezquer F, Conget P, Israel Y. Insulin is secreted upon glucose stimulation by both gastrointestinal enteroendocrine K-cells and L-cells engineered with the preproinsulin gene. Biol Res. 2011; 44(3):301-5.

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Johansson JK, Voss U, Kesavan G, Kostetskii I, Wierup N, Radice GL, Semb H. N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover. Genesis. 2010 Jun; 48(6):374-81.

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