Insulin-Secreting Cells

"Insulin-Secreting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.

Descriptor ID	D050417
MeSH Number(s)	A03.734.414.131 A06.390.131 A06.407.414.087 A11.382.625.092 A11.436.294.092
Concept/Terms	Insulin-Secreting Cells Insulin-Secreting Cells Cell, Insulin-Secreting Cells, Insulin-Secreting Insulin Secreting Cells Insulin-Secreting Cell beta Cells, Pancreatic Pancreatic beta Cell beta Cell, Pancreatic Pancreatic B Cells B Cell, Pancreatic B Cells, Pancreatic Pancreatic B Cell Pancreatic beta Cells

Below are MeSH descriptors whose meaning is more general than "Insulin-Secreting Cells".

Anatomy [A]
Digestive System [A03]
Pancreas [A03.734]
Islets of Langerhans [A03.734.414]
Insulin-Secreting Cells [A03.734.414.131]
Endocrine System [A06]
Enteroendocrine Cells [A06.390]
Insulin-Secreting Cells [A06.390.131]
Endocrine Glands [A06.407]
Islets of Langerhans [A06.407.414]
Insulin-Secreting Cells [A06.407.414.087]
Cells [A11]
Endocrine Cells [A11.382]
Enteroendocrine Cells [A11.382.625]
Insulin-Secreting Cells [A11.382.625.092]
Epithelial Cells [A11.436]
Enteroendocrine Cells [A11.436.294]
Insulin-Secreting Cells [A11.436.294.092]

Below are MeSH descriptors whose meaning is related to "Insulin-Secreting Cells".

Below are MeSH descriptors whose meaning is more specific than "Insulin-Secreting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin-Secreting Cells" by people in this website by year, and whether "Insulin-Secreting Cells" was a major or minor topic of these publications.

Bar chart showing 26 publications over 13 distinct years, with a maximum of 4 publications in 2007 and 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2006	1	0	1
2007	3	1	4
2008	1	0	1
2009	1	2	3
2010	2	1	3
2011	1	0	1
2012	4	0	4
2013	2	2	4
2014	0	1	1
2015	0	1	1
2017	1	0	1
2024	1	0	1

Below are the most recent publications written about "Insulin-Secreting Cells" by people in Profiles.

Varney MJ, Benovic JL. The Role of G Protein-Coupled Receptors and Receptor Kinases in Pancreatic ?-Cell Function and Diabetes. Pharmacol Rev. 2024 Feb 13; 76(2):267-299.

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Black LA, Zorina T. Genetic profile considerations for induction of allogeneic chimerism as a therapeutic approach for type 1 diabetes mellitus. Drug Discov Today. 2020 08; 25(8):1293-1297.

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Tsonkova VG, Sand FW, Wolf XA, Grunnet LG, Kirstine Ringgaard A, Ingvorsen C, Winkel L, Kalisz M, Dalgaard K, Bruun C, Fels JJ, Helgstrand C, Hastrup S, ?berg FK, Vernet E, Sandrini MPB, Shaw AC, Jessen C, Gr?nborg M, Hald J, Willenbrock H, Madsen D, Wernersson R, Hansson L, Jensen JN, Plesner A, Alanentalo T, Petersen MBK, Grapin-Botton A, Honor? C, Ahnfelt-R?nne J, Hecksher-S?rensen J, Ravassard P, Madsen OD, Rescan C, Frogne T. The EndoC-?H1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates. Mol Metab. 2018 02; 8:144-157.

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Tavecchio M, Lisanti S, Bennett MJ, Languino LR, Altieri DC. Deletion of Cyclophilin D Impairs ?-Oxidation and Promotes Glucose Metabolism. Sci Rep. 2015 Oct 30; 5:15981.

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Filippone EJ, Abubacker F, Farber JL. Posttransplantation normoglycemic diabetic nephropathy: the role of the allograft insulin resistance--a case report. Transplant Proc. 2014 Sep; 46(7):2381-5.

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Baldi JC, Manning PJ, Hofman PL, Walker RJ. Comment on: TODAY Study Group. Effects of metformin, metformin plus rosiglitazone, and metformin plus lifestyle on insulin sensitivity and ?-cell function in TODAY. Diabetes Care 2013;36:1749-1757. Diabetes Care. 2013 Dec; 36(12):e223.

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Levetan C, Pozzilli P, Jovanovic L, Schatz D. Proposal for generating new beta cells in a muted immune environment for type 1 diabetes. Diabetes Metab Res Rev. 2013 Nov; 29(8):604-6.

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Muniyappa R, Sable S, Ouwerkerk R, Mari A, Gharib AM, Walter M, Courville A, Hall G, Chen KY, Volkow ND, Kunos G, Huestis MA, Skarulis MC. Metabolic effects of chronic cannabis smoking. Diabetes Care. 2013 Aug; 36(8):2415-22.

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Levetan CS, Pierce SM. Distinctions between the islets of mice and men: implications for new therapies for type 1 and 2 diabetes. Endocr Pract. 2013 Mar-Apr; 19(2):301-12.

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Gadhia MM, Maliszewski AM, O'Meara MC, Thorn SR, Lavezzi JR, Limesand SW, Hay WW, Brown LD, Rozance PJ. Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase ?-cell mass in fetal sheep. Am J Physiol Endocrinol Metab. 2013 Feb 15; 304(4):E352-62.

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