Synaptosomal-Associated Protein 25
"Synaptosomal-Associated Protein 25" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.
Descriptor ID |
D050825
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MeSH Number(s) |
D12.776.543.512.249.500.750.500 D12.776.543.512.249.500.875.500 D12.776.543.990.775.500.750.500 D12.776.543.990.775.500.875.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synaptosomal-Associated Protein 25".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomal-Associated Protein 25".
This graph shows the total number of publications written about "Synaptosomal-Associated Protein 25" by people in this website by year, and whether "Synaptosomal-Associated Protein 25" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2011 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptosomal-Associated Protein 25" by people in Profiles.
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Egbujo CN, Sinclair D, Borgmann-Winter KE, Arnold SE, Turetsky BI, Hahn CG. Molecular evidence for decreased synaptic efficacy in the postmortem olfactory bulb of individuals with schizophrenia. Schizophr Res. 2015 Oct; 168(1-2):554-62.
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Li F, Pincet F, Perez E, Giraudo CG, Tareste D, Rothman JE. Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state. Nat Struct Mol Biol. 2011 Jul 24; 18(8):941-6.
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Krishnakumar SS, Radoff DT, Kümmel D, Giraudo CG, Li F, Khandan L, Baguley SW, Coleman J, Reinisch KM, Pincet F, Rothman JE. A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion. Nat Struct Mol Biol. 2011 Jul 24; 18(8):934-40.
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Eletto D, Russo G, Passiatore G, Del Valle L, Giordano A, Khalili K, Gualco E, Peruzzi F. Inhibition of SNAP25 expression by HIV-1 Tat involves the activity of mir-128a. J Cell Physiol. 2008 Sep; 216(3):764-70.
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Takida S, Wedegaertner PB. Exocytic pathway-independent plasma membrane targeting of heterotrimeric G proteins. FEBS Lett. 2004 Jun 4; 567(2-3):209-13.