"Syntaxin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neuronal cell membrane protein that combines with SNAP-25 and SYNAPTOBREVIN 2 to form a SNARE complex that leads to EXOCYTOSIS.
Descriptor ID |
D050827
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MeSH Number(s) |
D12.776.543.512.249.500.500.700 D12.776.543.990.775.500.500.700
|
Concept/Terms |
Syntaxin-2- Syntaxin-2
- Syntaxin 2
- Syntaxin-2 Protein
- Syntaxin 2 Protein
Syntaxin-1B- Syntaxin-1B
- Syntaxin 1B
- p35b Protein
- Syntaxin-1B Protein
- Syntaxin 1B Protein
- P35B Antigen
Syntaxin-1C- Syntaxin-1C
- Syntaxin 1C
- Syntaxin-1C Protein
- Syntaxin 1C Protein
Syntaxin-1A- Syntaxin-1A
- Syntaxin-1A Protein
- Syntaxin 1A Protein
- Syntaxin 1A
- HPC-1 Protein
- HPC 1 Protein
- Neuronal Cell Membrane Antigen, HPC-1
- Neuronal Cell Membrane Antigen, HPC 1
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Below are MeSH descriptors whose meaning is more general than "Syntaxin 1".
Below are MeSH descriptors whose meaning is more specific than "Syntaxin 1".
This graph shows the total number of publications written about "Syntaxin 1" by people in this website by year, and whether "Syntaxin 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2011 | 1 | 3 | 4 |
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Below are the most recent publications written about "Syntaxin 1" by people in Profiles.
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Shi L, Kümmel D, Coleman J, Melia TJ, Giraudo CG. Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex. Mol Biol Cell. 2011 Nov; 22(21):4150-60.
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Kümmel D, Krishnakumar SS, Radoff DT, Li F, Giraudo CG, Pincet F, Rothman JE, Reinisch KM. Complexin cross-links prefusion SNAREs into a zigzag array. Nat Struct Mol Biol. 2011 Jul 24; 18(8):927-33.
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Li F, Pincet F, Perez E, Giraudo CG, Tareste D, Rothman JE. Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state. Nat Struct Mol Biol. 2011 Jul 24; 18(8):941-6.
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Krishnakumar SS, Radoff DT, Kümmel D, Giraudo CG, Li F, Khandan L, Baguley SW, Coleman J, Reinisch KM, Pincet F, Rothman JE. A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion. Nat Struct Mol Biol. 2011 Jul 24; 18(8):934-40.
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Shen J, Tareste DC, Paumet F, Rothman JE, Melia TJ. Selective activation of cognate SNAREpins by Sec1/Munc18 proteins. Cell. 2007 Jan 12; 128(1):183-95.
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Cibulsky SM, Fei H, Levitan IB. Syntaxin-1A binds to and modulates the Slo calcium-activated potassium channel via an interaction that excludes syntaxin binding to calcium channels. J Neurophysiol. 2005 Mar; 93(3):1393-405.