Large-Conductance Calcium-Activated Potassium Channels
"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
| Descriptor ID |
D051036
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| MeSH Number(s) |
D12.776.157.530.400.600.150.500 D12.776.543.550.450.750.150.500 D12.776.543.585.400.750.150.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Al-Khazali HM, Christensen RH, Dodick DW, Chaudhry BA, Melchior AG, Burstein R, Ashina H. Hypersensitivity to BKCa channel opening in persistent post-traumatic headache. J Headache Pain. 2024 Jun 18; 25(1):102.
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Gururaja Rao S, Bednarczyk P, Towheed A, Shah K, Karekar P, Ponnalagu D, Jensen HN, Addya S, Reyes BAS, Van Bockstaele EJ, Szewczyk A, Wallace DC, Singh H. BKCa (Slo) Channel Regulates Mitochondrial Function and Lifespan in Drosophila melanogaster. Cells. 2019 08 21; 8(9).
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Levitan IB. Sugar and spice and potassium channel modulation. Channels (Austin). 2017 07 04; 11(4):263-264.
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Bisen S, Seleverstov O, Belani J, Rychnovsky S, Dopico AM, Bukiya AN. Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction. Biochim Biophys Acta. 2016 11; 1861(11):1756-1766.
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Jepson JE, Shahidullah M, Liu D, le Marchand SJ, Liu S, Wu MN, Levitan IB, Dalva MB, Koh K. Regulation of synaptic development and function by the Drosophila PDZ protein Dyschronic. Development. 2014 Dec; 141(23):4548-57.
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Jepson JE, Shahidullah M, Lamaze A, Peterson D, Pan H, Koh K. dyschronic, a Drosophila homolog of a deaf-blindness gene, regulates circadian output and Slowpoke channels. PLoS Genet. 2012; 8(4):e1002671.
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Tabak J, Tomaiuolo M, Gonzalez-Iglesias AE, Milescu LS, Bertram R. Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study. J Neurosci. 2011 Nov 16; 31(46):16855-63.
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Sheldon AL, Zhang J, Fei H, Levitan IB. SLOB, a SLOWPOKE channel binding protein, regulates insulin pathway signaling and metabolism in Drosophila. PLoS One. 2011; 6(8):e23343.
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Bukiya AN, Belani JD, Rychnovsky S, Dopico AM. Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions. J Gen Physiol. 2011 Jan; 137(1):93-110.
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Deshpande DA, Wang WC, McIlmoyle EL, Robinett KS, Schillinger RM, An SS, Sham JS, Liggett SB. Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. Nat Med. 2010 Nov; 16(11):1299-304.