"Plakins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of related proteins that associate with cytoskeletal elements and junctional complexes at INTERCELLULAR JUNCTIONS. Plakins share a common plakin domain or a plakin repeat domain.
| Descriptor ID |
D051179
|
| MeSH Number(s) |
D12.776.220.790
|
| Concept/Terms |
Plakins- Plakins
- Cytoskeletal Adaptor Proteins
- Adaptor Proteins, Cytoskeletal
- Cytoskeletal Linker Proteins
- Cytolinker Proteins
|
Below are MeSH descriptors whose meaning is more general than "Plakins".
Below are MeSH descriptors whose meaning is more specific than "Plakins".
This graph shows the total number of publications written about "Plakins" by people in this website by year, and whether "Plakins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Plakins" by people in Profiles.
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Sevilla LM, Nachat R, Groot KR, Klement JF, Uitto J, Djian P, Määttä A, Watt FM. Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. J Cell Biol. 2007 Dec 31; 179(7):1599-612.
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McGrath JA. Inherited disorders of desmosomes. Australas J Dermatol. 2005 Nov; 46(4):221-9.
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Kalinin AE, Kalinin AE, Aho M, Uitto J, Aho S. Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region. J Invest Dermatol. 2005 Jan; 124(1):46-55.
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Aho S, Li K, Ryoo Y, McGee C, Ishida-Yamamoto A, Uitto J, Klement JF. Periplakin gene targeting reveals a constituent of the cornified cell envelope dispensable for normal mouse development. Mol Cell Biol. 2004 Jul; 24(14):6410-8.
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Kazerounian S, Uitto J, Aho S. Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentin. Exp Dermatol. 2002 Oct; 11(5):428-38.