"gamma Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-functional catenin that is highly homologous to BETA CATENIN. Gamma catenin binds CADHERINS and helps link their cytoplasmic tails to ACTIN in the CYTOSKELETON via ALPHA CATENIN. It is also found in DESMOSOMES where it mediates the link between DESMOSOMAL CADHERINS and DESMOPLAKIN.
Descriptor ID |
D051185
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MeSH Number(s) |
D12.776.091.500 D12.776.220.145.750
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Concept/Terms |
gamma Catenin- gamma Catenin
- Catenin, gamma
- Desmoplakin III
- Junctional Plakoglobin
- Plakoglobin, Junctional
- Plakoglobin
- Junction Plakoglobin
- Plakoglobin, Junction
- gamma-Catenin
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Below are MeSH descriptors whose meaning is more general than "gamma Catenin".
Below are MeSH descriptors whose meaning is more specific than "gamma Catenin".
This graph shows the total number of publications written about "gamma Catenin" by people in this website by year, and whether "gamma Catenin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "gamma Catenin" by people in Profiles.
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Swope D, Cheng L, Gao E, Li J, Radice GL. Loss of cadherin-binding proteins ß-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis. Mol Cell Biol. 2012 Mar; 32(6):1056-67.
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Li J, Swope D, Raess N, Cheng L, Muller EJ, Radice GL. Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol. 2011 Mar; 31(6):1134-44.
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Leonard M, Chan Y, Menko AS. Identification of a novel intermediate filament-linked N-cadherin/gamma-catenin complex involved in the establishment of the cytoarchitecture of differentiated lens fiber cells. Dev Biol. 2008 Jul 15; 319(2):298-308.
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Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA. Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. Carcinogenesis. 2002 Jan; 23(1):107-14.