Hepatocyte Nuclear Factor 1-alpha
"Hepatocyte Nuclear Factor 1-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hepatocyte nuclear factor 1-alpha is a transcription factor found in the LIVER; PANCREAS; and KIDNEY that regulates HOMEOSTASIS of GLUCOSE.
| Descriptor ID |
D051538
|
| MeSH Number(s) |
D12.776.260.262.500.500 D12.776.260.400.218.500 D12.776.660.352.500.500 D12.776.930.318.500.500
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1-alpha- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1 alpha
- LFB1 Transcription Factor
- Liver-Specific Transcription Factor LF-B1
- Liver Specific Transcription Factor LF B1
- Albumin Proximal Factor
- HNF-1alpha
- HNF 1alpha
- Hepatocyte Nuclear Factor 1alpha
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1-alpha".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1-alpha".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in Profiles.
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Fahl SP, Contreras AV, Verma A, Qiu X, Harly C, Radtke F, Z??iga-Pfl?cker JC, Murre C, Xue HH, Sen JM, Wiest DL. The E protein-TCF1 axis controls ?d T?cell development and effector fate. Cell Rep. 2021 02 02; 34(5):108716.
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Schick UM, Auer PL, Bis JC, Lin H, Wei P, Pankratz N, Lange LA, Brody J, Stitziel NO, Kim DS, Carlson CS, Fornage M, Haessler J, Hsu L, Jackson RD, Kooperberg C, Leal SM, Psaty BM, Boerwinkle E, Tracy R, Ardissino D, Shah S, Willer C, Loos R, Melander O, Mcpherson R, Hovingh K, Reilly M, Watkins H, Girelli D, Fontanillas P, Chasman DI, Gabriel SB, Gibbs R, Nickerson DA, Kathiresan S, Peters U, Dupuis J, Wilson JG, Rich SS, Morrison AC, Benjamin EJ, Gross MD, Reiner AP. Association of exome sequences with plasma C-reactive protein levels in >9000 participants. Hum Mol Genet. 2015 Jan 15; 24(2):559-71.
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Gragnoli C. PSMD9 is linked to MODY3. J Cell Physiol. 2010 Apr; 223(1):1-5.
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Gragnoli C, Cockburn BN, Chiaramonte F, Gorini A, Marietti G, Marozzi G, Signorini AM. Early-onset Type II diabetes mellitus in Italian families due to mutations in the genes encoding hepatic nuclear factor 1 alpha and glucokinase. Diabetologia. 2001 Oct; 44(10):1326-9.
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Godart F, Bellanné-Chantelot C, Clauin S, Gragnoli C, Abderrahmani A, Blanché H, Boutin P, Chèvre JC, Froguel P, Bailleul B. Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients. Hum Mutat. 2000; 15(2):173-80.
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Gragnoli C, Lindner T, Cockburn BN, Kaisaki PJ, Gragnoli F, Marozzi G, Bell GI. Maturity-onset diabetes of the young due to a mutation in the hepatocyte nuclear factor-4 alpha binding site in the promoter of the hepatocyte nuclear factor-1 alpha gene. Diabetes. 1997 Oct; 46(10):1648-51.