"Heme Oxygenase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous stress-responsive enzyme that catalyzes the oxidative cleavage of HEME to yield IRON; CARBON MONOXIDE; and BILIVERDIN.
| Descriptor ID |
D051547
|
| MeSH Number(s) |
D08.811.682.690.708.410.500
|
| Concept/Terms |
Heme Oxygenase-1- Heme Oxygenase-1
- Heme Oxygenase 1
- Oxygenase-1, Heme
- Hemeoxygenase 1
|
Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase-1".
Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase-1".
This graph shows the total number of publications written about "Heme Oxygenase-1" by people in this website by year, and whether "Heme Oxygenase-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 3 | 6 |
| 2007 | 3 | 1 | 4 |
| 2008 | 2 | 3 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 1 | 3 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heme Oxygenase-1" by people in Profiles.
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Schutzman DL, Gatien E, Ajayi S, Wong RJ. Heme oxygenase-1 genetic variants and the conundrum of hyperbilirubinemia in African-American newborns. J Perinatol. 2018 04; 38(4):345-350.
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Hama M, Kirino Y, Takeno M, Takase K, Miyazaki T, Yoshimi R, Ueda A, Itoh-Nakadai A, Muto A, Igarashi K, Ishigatsubo Y. Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways. Arthritis Rheum. 2012 May; 64(5):1518-28.
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Chen-Roetling J, Liu W, Regan RF. Hemopexin decreases hemin accumulation and catabolism by neural cells. Neurochem Int. 2012 Apr; 60(5):488-94.
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Kwok SC, Samuel SP, Handal J. Atorvastatin activates heme oxygenase-1 at the stress response elements. J Cell Mol Med. 2012 Feb; 16(2):394-400.
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Chen-Roetling J, Liu W, Regan RF. Iron accumulation and neurotoxicity in cortical cultures treated with holotransferrin. Free Radic Biol Med. 2011 Dec 1; 51(11):1966-74.
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Metz R, Duhadaway JB, Rust S, Munn DH, Muller AJ, Mautino M, Prendergast GC. Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase. Mol Cancer Ther. 2010 Jun; 9(6):1864-71.
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Jaremko KM, Chen-Roetling J, Chen L, Regan RF. Accelerated hemolysis and neurotoxicity in neuron-glia-blood clot co-cultures. J Neurochem. 2010 Aug; 114(4):1063-73.
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Miyazaki T, Kirino Y, Takeno M, Samukawa S, Hama M, Tanaka M, Yamaji S, Ueda A, Tomita N, Fujita H, Ishigatsubo Y. Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1. Cancer Sci. 2010 Jun; 101(6):1409-16.
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Miyazaki T, Kirino Y, Takeno M, Hama M, Ushihama A, Watanabe R, Takase K, Tachibana T, Matsumoto K, Tanaka M, Yamaji S, Ideguchi H, Tomita N, Fujita H, Ohno S, Ueda A, Ishigatsubo Y. Serum HO-1 is useful to make differential diagnosis of secondary hemophagocytic syndrome from other similar hematological conditions. Int J Hematol. 2010 Mar; 91(2):229-37.
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Chen-Roetling J, Li Z, Chen M, Awe OO, Regan RF. Heme oxygenase activity and hemoglobin neurotoxicity are attenuated by inhibitors of the MEK/ERK pathway. Neuropharmacology. 2009 Apr; 56(5):922-8.