Glutathione S-Transferase pi
"Glutathione S-Transferase pi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glutathione transferase that catalyzes the conjugation of electrophilic substrates to GLUTATHIONE. This enzyme has been shown to provide cellular protection against redox-mediated damage by FREE RADICALS.
| Descriptor ID |
D051549
|
| MeSH Number(s) |
D08.811.913.225.500.500
|
| Concept/Terms |
Glutathione Transferase P1-1- Glutathione Transferase P1-1
- Glutathione Transferase P1 1
- Transferase P1-1, Glutathione
- GSTP1 Glutathione D-Transferase
- D-Transferase, GSTP1 Glutathione
- GSTP1 Glutathione D Transferase
- Glutathione D-Transferase, GSTP1
|
Below are MeSH descriptors whose meaning is more general than "Glutathione S-Transferase pi".
Below are MeSH descriptors whose meaning is more specific than "Glutathione S-Transferase pi".
This graph shows the total number of publications written about "Glutathione S-Transferase pi" by people in this website by year, and whether "Glutathione S-Transferase pi" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutathione S-Transferase pi" by people in Profiles.
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Karadag R, Bayram N, Oguztuzun S, Bozer B, Bayramlar H, Simsek GG, Rapuano CJ. Investigation of Glutathione S-Transferase Isoenzyme Protein Expression in Patients With Pterygium. Cornea. 2016 Aug; 35(8):1089-92.
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Mian OY, Khattab MH, Hedayati M, Coulter J, Abubaker-Sharif B, Schwaninger JM, Veeraswamy RK, Brooks JD, Hopkins L, Shinohara DB, Cornblatt B, Nelson WG, Yegnasubramanian S, DeWeese TL. GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress. Prostate. 2016 Feb; 76(2):199-206.
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Eisen HJ. Glutathione s-transferase Pi-1: a novel approach to mitigating adverse cardiac remodeling after myocardial infarction. J Card Fail. 2014 Feb; 20(2):146-7.
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Korff A, Pfeiffer B, Smeyne M, Kocak M, Pfeiffer RF, Smeyne RJ. Alterations in glutathione S-transferase pi expression following exposure to MPP+ -induced oxidative stress in the blood of Parkinson's disease patients. Parkinsonism Relat Disord. 2011 Dec; 17(10):765-8.
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Schroer KT, Gibson AM, Sivaprasad U, Bass SA, Ericksen MB, Wills-Karp M, Lecras T, Fitzpatrick AM, Brown LA, Stringer KF, Hershey GK. Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress. J Allergy Clin Immunol. 2011 Sep; 128(3):539-48.
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Thévenin AF, Zony CL, Bahnson BJ, Colman RF. GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Sci. 2011 May; 20(5):834-48.
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Yao S, Barlow WE, Albain KS, Choi JY, Zhao H, Livingston RB, Davis W, Rae JM, Yeh IT, Hutchins LF, Ravdin PM, Martino S, Lyss AP, Osborne CK, Abeloff M, Hortobagyi GN, Hayes DF, Ambrosone CB. Gene polymorphisms in cyclophosphamide metabolism pathway,treatment-related toxicity, and disease-free survival in SWOG 8897 clinical trial for breast cancer. Clin Cancer Res. 2010 Dec 15; 16(24):6169-76.
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Huang YC, Misquitta S, Blond SY, Adams E, Colman RF. Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. J Biol Chem. 2008 Nov 21; 283(47):32880-8.
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Ralat LA, Misquitta SA, Manevich Y, Fisher AB, Colman RF. Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Arch Biochem Biophys. 2008 Jun 1; 474(1):109-18.
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Smeyne M, Boyd J, Raviie Shepherd K, Jiao Y, Pond BB, Hatler M, Wolf R, Henderson C, Smeyne RJ. GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. Proc Natl Acad Sci U S A. 2007 Feb 6; 104(6):1977-82.