Glutathione S-Transferase pi
"Glutathione S-Transferase pi" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glutathione transferase that catalyzes the conjugation of electrophilic substrates to GLUTATHIONE. This enzyme has been shown to provide cellular protection against redox-mediated damage by FREE RADICALS.
| Descriptor ID |
D051549
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| MeSH Number(s) |
D08.811.913.225.500.500
|
| Concept/Terms |
Glutathione Transferase P1-1- Glutathione Transferase P1-1
- Glutathione Transferase P1 1
- Transferase P1-1, Glutathione
- GSTP1 Glutathione D-Transferase
- D-Transferase, GSTP1 Glutathione
- GSTP1 Glutathione D Transferase
- Glutathione D-Transferase, GSTP1
|
Below are MeSH descriptors whose meaning is more general than "Glutathione S-Transferase pi".
Below are MeSH descriptors whose meaning is more specific than "Glutathione S-Transferase pi".
This graph shows the total number of publications written about "Glutathione S-Transferase pi" by people in this website by year, and whether "Glutathione S-Transferase pi" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2011 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutathione S-Transferase pi" by people in Profiles.
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Mian OY, Khattab MH, Hedayati M, Coulter J, Abubaker-Sharif B, Schwaninger JM, Veeraswamy RK, Brooks JD, Hopkins L, Shinohara DB, Cornblatt B, Nelson WG, Yegnasubramanian S, DeWeese TL. GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress. Prostate. 2016 Feb; 76(2):199-206.
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Korff A, Pfeiffer B, Smeyne M, Kocak M, Pfeiffer RF, Smeyne RJ. Alterations in glutathione S-transferase pi expression following exposure to MPP+ -induced oxidative stress in the blood of Parkinson's disease patients. Parkinsonism Relat Disord. 2011 Dec; 17(10):765-8.
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Thévenin AF, Zony CL, Bahnson BJ, Colman RF. GST pi modulates JNK activity through a direct interaction with JNK substrate, ATF2. Protein Sci. 2011 May; 20(5):834-48.
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Huang YC, Misquitta S, Blond SY, Adams E, Colman RF. Catalytically active monomer of glutathione S-transferase pi and key residues involved in the electrostatic interaction between subunits. J Biol Chem. 2008 Nov 21; 283(47):32880-8.
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Ralat LA, Misquitta SA, Manevich Y, Fisher AB, Colman RF. Characterization of the complex of glutathione S-transferase pi and 1-cysteine peroxiredoxin. Arch Biochem Biophys. 2008 Jun 1; 474(1):109-18.
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Smeyne M, Boyd J, Raviie Shepherd K, Jiao Y, Pond BB, Hatler M, Wolf R, Henderson C, Smeyne RJ. GSTpi expression mediates dopaminergic neuron sensitivity in experimental parkinsonism. Proc Natl Acad Sci U S A. 2007 Feb 6; 104(6):1977-82.
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Ralat LA, Colman RF. Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. Biochemistry. 2006 Oct 17; 45(41):12491-9.
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Ralat LA, Manevich Y, Fisher AB, Colman RF. Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes. Biochemistry. 2006 Jan 17; 45(2):360-72.
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Ralat LA, Colman RF. Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site. J Biol Chem. 2004 Nov 26; 279(48):50204-13.
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Ralat LA, Colman RF. Monobromobimane occupies a distinct xenobiotic substrate site in glutathione S-transferase pi. Protein Sci. 2003 Nov; 12(11):2575-87.