beta-Adrenergic Receptor Kinases
"beta-Adrenergic Receptor Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
G-protein-coupled receptor kinases that mediate agonist-dependent PHOSPHORYLATION and desensitization of BETA-ADRENERGIC RECEPTORS.
| Descriptor ID |
D051552
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.364.049 D12.644.360.293.249 D12.776.476.293.249
|
| Concept/Terms |
beta-Adrenergic Receptor Kinases- beta-Adrenergic Receptor Kinases
- Receptor Kinases, beta-Adrenergic
- beta Adrenergic Receptor Kinases
- beta-AR Kinase
- beta AR Kinase
- beta-Adrenergic Receptor Kinase
- Receptor Kinase, beta-Adrenergic
- beta Adrenergic Receptor Kinase
|
Below are MeSH descriptors whose meaning is more general than "beta-Adrenergic Receptor Kinases".
Below are MeSH descriptors whose meaning is more specific than "beta-Adrenergic Receptor Kinases".
This graph shows the total number of publications written about "beta-Adrenergic Receptor Kinases" by people in this website by year, and whether "beta-Adrenergic Receptor Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 4 | 4 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Adrenergic Receptor Kinases" by people in Profiles.
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Katz MG, Fargnoli AS, Swain JD, Tomasulo CE, Ciccarelli M, Huang ZM, Rabinowitz JE, Bridges CR. AAV6-?ARKct gene delivery mediated by molecular cardiac surgery with recirculating delivery (MCARD) in sheep results in robust gene expression and increased adrenergic reserve. J Thorac Cardiovasc Surg. 2012 Mar; 143(3):720-726.e3.
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Vinge LE, Andressen KW, Attramadal T, Andersen GĂ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H. Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function. Mol Pharmacol. 2007 Sep; 72(3):582-91.
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Billington CK, Kong KC, Bhattacharyya R, Wedegaertner PB, Panettieri RA, Chan TO, Penn RB. Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth. Biochemistry. 2005 Nov 8; 44(44):14595-605.
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Wu JH, Goswami R, Kim LK, Miller WE, Peppel K, Freedman NJ. The platelet-derived growth factor receptor-beta phosphorylates and activates G protein-coupled receptor kinase-2. A mechanism for feedback inhibition. J Biol Chem. 2005 Sep 2; 280(35):31027-35.
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Hardy AR, Conley PB, Luo J, Benovic JL, Poole AW, Mundell SJ. P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms. Blood. 2005 May 1; 105(9):3552-60.
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Pao CS, Benovic JL. Structure/function analysis of alpha2A-adrenergic receptor interaction with G protein-coupled receptor kinase 2. J Biol Chem. 2005 Mar 25; 280(12):11052-8.
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Iwata K, Luo J, Penn RB, Benovic JL. Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2. J Biol Chem. 2005 Jan 21; 280(3):2197-204.
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Day PW, Tesmer JJ, Sterne-Marr R, Freeman LC, Benovic JL, Wedegaertner PB. Characterization of the GRK2 binding site of Galphaq. J Biol Chem. 2004 Dec 17; 279(51):53643-52.
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Hildreth KL, Wu JH, Barak LS, Exum ST, Kim LK, Peppel K, Freedman NJ. Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor. J Biol Chem. 2004 Oct 1; 279(40):41775-82.
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Luo J, Benovic JL. G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. J Biol Chem. 2003 Dec 19; 278(51):50908-14.